Strain Name:
C57BL/6J-MtgxR6562Btlr/Mmmh
Stock Number:
044686-MU
Citation ID:
RRID:MMRRC_044686-MU
Other Names:
R6562 (G1)
Major Collection:

Strain Information

Kcnmb4
Name: potassium large conductance calcium-activated channel, subfamily M, beta member 4
Synonyms: 2900045G12Rik, Slowpoke beta 4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 58802
HGNC: HGNC:6289
Homologene: 8721
Plin2
Name: perilipin 2
Synonyms: Adfp, adipophilin, Adrp, ADPH
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11520
HGNC: HGNC:248
Homologene: 872
Ankrd13a
Name: ankyrin repeat domain 13a
Synonyms: 1100001D10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68420
Homologene: 23814
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: LOC237877, C130052G03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237877
Homologene: 32611
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320365
Homologene: 113770
Akap12
Name: A kinase anchor protein 12
Synonyms: Tsga12, SSeCKS, Srcs5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83397
VEGA: 10
HGNC: HGNC:370
Homologene: 3740
Tead1
Name: TEA domain family member 1
Synonyms: TEF-1, B230114H05Rik, mTEF-1, Gtrgeo5, Tcf13, TEAD-1, 2610024B07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21676
Homologene: 2418
Lamb2
Name: laminin, beta 2
Synonyms: Lams, npht, Lamb-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16779
HGNC: HGNC:6487
Homologene: 1723
Lrmda
Name: leucine rich melanocyte differentiation associated
Synonyms: Oca7, 1700112E06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 76633
Homologene: 49975
Ctnnd1
Name: catenin delta 1
Synonyms: catenin (cadherin associated protein), delta 1, P120, Catns, p120-catenin, Ctnnd
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12388
HGNC: HGNC:2515
Homologene: 1017
Actr8
Name: ARP8 actin-related protein 8
Synonyms: 5730542K05Rik, ARP8
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56249
VEGA: 14
Homologene: 11286
Dock7
Name: dedicator of cytokinesis 7
Synonyms: LOC242555, 3110056M06Rik, m
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67299
Homologene: 23566
Ankrd13c
Name: ankyrin repeat domain 13c
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 433667
Homologene: 41804
Ube2d1
Name: ubiquitin-conjugating enzyme E2D 1
Synonyms: UBCH5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216080
Homologene: 20714
Zfp451
Name: zinc finger protein 451
Synonyms: Kiaa0576-hp, 4933435G09Rik, 4930515K21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98403
Homologene: 9188
Fcrl2
Name: Fc receptor like 2
Synonyms: Msr2, Fcrls, Fcrh2, IFGP2, 2810439C17Rik, moFcRH2sc
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80891
Homologene: 57117
Abt1
Name: activator of basal transcription 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 30946
Homologene: 134288
Nutf2
Name: nuclear transport factor 2
Synonyms: Ntf2, PP15, 2700067I02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68051
Homologene: 110745
Arhgef3
Name: Rho guanine nucleotide exchange factor 3
Synonyms: 1200004I24Rik, 9830169H03Rik, C76747
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71704
VEGA: 14
HGNC: HGNC:683
Homologene: 41329
Kat6a
Name: K(lysine) acetyltransferase 6A
Synonyms: 9930021N24Rik, MOZ, Myst3, Zfp220
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244349
Homologene: 4924
Siglecg
Name: sialic acid binding Ig-like lectin G
Synonyms: A630096C01Rik, mSiglec-G
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243958
Homologene: 13228
Arhgef28
Name: Rho guanine nucleotide exchange factor 28
Synonyms: D13Bwg1089e, p190RhoGEF, RIP2, Rho specific exchange factor, RhoGEF, 9230110L08Rik, Rgnef
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110596
VEGA: 13
Homologene: 8078
Rel
Name: reticuloendotheliosis oncogene
Synonyms: c-Rel
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19696
HGNC: HGNC:9954
Homologene: 2182
Ndst3
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Synonyms: 4921531K01Rik, 4930511P15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83398
HGNC: HGNC:7682
Homologene: 3513
Zcchc14
Name: zinc finger, CCHC domain containing 14
Synonyms: Bdg29
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 142682
Homologene: 9037
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Gm17067
Name: predicted gene 17067
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 115486519
Entpd5
Name: ectonucleoside triphosphate diphosphohydrolase 5
Synonyms: Cd39l4, NTPDase-5, mNTPase, NTPDase5, ER-UDPase, Pcph
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12499
HGNC: HGNC:3367
Homologene: 37457
Krt6a
Name: keratin 6A
Synonyms: mK6[a], Krt2-6c, MK6a, Krt2-6a
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16687
VEGA: 15
Homologene: 136794
Spata31e2
Name: spermatogenesis associated 31 subfamily E member 2
Synonyms: 4931408C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210940
Homologene: 86827
Gbgt1
Name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227671
Homologene: 110677
Prdm8
Name: PR domain containing 8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77630
Homologene: 129760
L3mbtl1
Name: L3MBTL1 histone methyl-lysine binding protein
Synonyms: L3MBTL1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241764
Homologene: 41846
Vwde
Name: von Willebrand factor D and EGF domains
Synonyms: LOC232585
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232585
Homologene: 35456
Slc9a3
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3
Synonyms: NHE-3, NHE3, 9030624O13Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105243
VEGA: 13
Homologene: 55804
Or6c211
Name: olfactory receptor family 6 subfamily C member 211
Synonyms: GA_x6K02T2PULF-11349138-11348182, MOR110-10, Olfr801
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258282
Homologene: 138306
Pik3r3
Name: phosphoinositide-3-kinase regulatory subunit 3
Synonyms: p55pik, p55
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18710
HGNC: HGNC:8981
Homologene: 2690
Trim12c
Name: tripartite motif-containing 12C
Synonyms: Trim12-2, 9230105E10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319236
Homologene: 75345
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18080
Homologene: 40632
Slc39a10
Name: solute carrier family 39 (zinc transporter), member 10
Synonyms: 2900042E17Rik, Zip10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227059
Homologene: 34076
Ccdc158
Name: coiled-coil domain containing 158
Synonyms: 4932413O14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320696
Homologene: 18560
Ovgp1
Name: oviductal glycoprotein 1
Synonyms: mucin 9, MOGP, Chit5, OGP, muc9, oviductin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12659
HGNC: HGNC:8524
Homologene: 74442
Cenpu
Name: centromere protein U
Synonyms: Mlf1ip, 1700029A22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71876
Homologene: 11629
Pkn3
Name: protein kinase N3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 263803
Homologene: 50980
Tmem67
Name: transmembrane protein 67
Synonyms: b2b1291.1Clo, 5330408M12Rik, b2b1163.1Clo
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329795
Homologene: 71886
Slc13a1
Name: solute carrier family 13 (sodium/sulfate symporters), member 1
Synonyms: Nas1, NaSi-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 55961
Homologene: 31893
Bbs12
Name: Bardet-Biedl syndrome 12
Synonyms: LOC386537, LOC241950, LOC241950
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241950
Homologene: 17634
Vmn2r24
Name: vomeronasal 2, receptor 24
Synonyms: EG243628
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243628
Homologene: 135915
Pgghg
Name: protein glucosylgalactosylhydroxylysine glucosidase
Synonyms: 5730511L01Rik, Athl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212974
Homologene: 16023
Sult2b1
Name: sulfotransferase family, cytosolic, 2B, member 1
Synonyms: Gm5897, SULT2B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54200
Homologene: 49487
Dcpp3
Name: demilune cell and parotid protein 3
Synonyms: EG620253
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 620253
VEGA: 17
Homologene: 103921
Ehd2
Name: EH-domain containing 2
Synonyms: C130052H20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259300
HGNC: HGNC:3243
Homologene: 22825
Cd200l1
Name: CD200 molecule like 1
Synonyms: Gm609, iSEC1, LOC208166, LOC385647
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208166
Homologene: 86707
4933434E20Rik
Name: RIKEN cDNA 4933434E20 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99650
Homologene: 41041
Ccdc169
Name: coiled-coil domain containing 169
Synonyms: A730037C10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320604
Homologene: 77607
Wdr54
Name: WD repeat domain 54
Synonyms: 1700030E05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 75659
Homologene: 11382
Lysmd2
Name: LysM, putative peptidoglycan-binding, domain containing 2
Synonyms: 2210402C18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70082
VEGA: 9
Homologene: 12347
Cnrip1
Name: cannabinoid receptor interacting protein 1
Synonyms: 3110054C06Rik, 1500041B16Rik, 5330437A18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380686
Homologene: 9153
Frmpd2
Name: FERM and PDZ domain containing 2
Synonyms: Gm626, LOC380890, ENSMUSG00000071536, LOC268729, Frmpd2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268729
Homologene: 51854
Gm5565
Name: predicted gene 5565
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433961
Homologene: 86127
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 26,682,362 bp
  • C to A, chromosome 1 at 33,762,179 bp
  • T to A, chromosome 1 at 46,835,564 bp
  • A to T, chromosome 2 at 28,504,886 bp
  • G to T, chromosome 2 at 30,080,687 bp
  • A to G, chromosome 2 at 84,624,308 bp
  • C to T, chromosome 2 at 162,970,204 bp
  • A to G, chromosome 3 at 37,320,240 bp
  • A to G, chromosome 3 at 55,150,814 bp
  • A to C, chromosome 3 at 87,257,328 bp
  • A to G, chromosome 3 at 90,063,236 bp
  • A to G, chromosome 3 at 105,980,273 bp
  • A to G, chromosome 3 at 123,552,532 bp
  • T to A, chromosome 3 at 157,999,672 bp
  • A to G, chromosome 4 at 12,053,445 bp
  • A to T, chromosome 4 at 86,658,595 bp
  • A to T, chromosome 4 at 98,991,410 bp
  • C to T, chromosome 4 at 116,299,809 bp
  • T to G, chromosome 5 at 92,662,722 bp
  • T to C, chromosome 5 at 98,183,343 bp
  • C to A, chromosome 5 at 114,804,392 bp
  • G to T, chromosome 5 at 146,158,154 bp
  • T to C, chromosome 5 at 150,326,149 bp
  • T to A, chromosome 6 at 13,193,123 bp
  • T to A, chromosome 6 at 24,150,793 bp
  • A to T, chromosome 6 at 83,155,068 bp
  • A to T, chromosome 6 at 123,780,427 bp
  • C to A, chromosome 7 at 15,957,567 bp
  • A to T, chromosome 7 at 42,708,729 bp
  • A to G, chromosome 7 at 43,409,057 bp
  • A to C, chromosome 7 at 45,742,246 bp
  • A to T, chromosome 7 at 104,345,134 bp
  • A to G, chromosome 7 at 112,861,443 bp
  • A to G, chromosome 7 at 140,946,593 bp
  • T to C, chromosome 8 at 22,911,787 bp
  • T to C, chromosome 8 at 46,572,823 bp
  • G to T, chromosome 8 at 105,875,626 bp
  • A to T, chromosome 8 at 121,604,103 bp
  • C to T, chromosome 9 at 75,635,409 bp
  • A to T, chromosome 9 at 108,487,008 bp
  • G to T, chromosome 10 at 4,356,141 bp
  • C to T, chromosome 10 at 71,262,241 bp
  • A to T, chromosome 10 at 116,473,184 bp
  • G to A, chromosome 10 at 129,670,139 bp
  • G to A, chromosome 11 at 17,078,539 bp
  • C to A, chromosome 11 at 23,757,026 bp
  • T to C, chromosome 11 at 80,133,206 bp
  • T to C, chromosome 12 at 70,055,954 bp
  • T to C, chromosome 12 at 84,386,200 bp
  • T to G, chromosome 13 at 23,423,588 bp
  • T to A, chromosome 13 at 74,155,161 bp
  • A to G, chromosome 13 at 97,988,139 bp
  • T to C, chromosome 14 at 22,598,186 bp
  • A to T, chromosome 14 at 27,152,996 bp
  • A to G, chromosome 14 at 29,986,454 bp
  • T to A, chromosome 14 at 33,571,915 bp
  • T to A, chromosome 15 at 101,691,659 bp
  • C to T, chromosome 16 at 45,444,079 bp
  • AGGCCATGCTGGCC to AGGCC, chromosome 17 at 23,917,598 bp
  • T to A, chromosome 19 at 18,838,042 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6562 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044686-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.