Strain Name:
C57BL/6J-MtgxR6901Btlr/Mmmh
Stock Number:
044995-MU
Citation ID:
RRID:MMRRC_044995-MU
Other Names:
R6901 (G1)
Major Collection:

Strain Information

Hnrnpab
Name: heterogeneous nuclear ribonucleoprotein A/B
Synonyms: CBF-A, Hnrpab, Cgbfa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15384
HGNC: HGNC:5034
Homologene: 74950
Pex7
Name: peroxisomal biogenesis factor 7
Synonyms: peroxisome biogenesis factor 7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18634
HGNC: HGNC:8860
Homologene: 242
Nbea
Name: neurobeachin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 26422
HGNC: HGNC:7648
Homologene: 69190
Gse1
Name: genetic suppressor element 1, coiled-coil protein
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382034
Homologene: 40964
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: rim2, AP-3, Hps2, recombination induced mutation 2, beta3A
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki-67, Ki67, D630048A14Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Arid4a
Name: AT-rich interaction domain 4A
Synonyms: Rbbp1, A630067N03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238247
HGNC: HGNC:9885
Homologene: 11303
Abhd5
Name: abhydrolase domain containing 5
Synonyms: 1300003D03Rik, 2010002J10Rik, CGI-58, IECN5, NCIE2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67469
Homologene: 41088
Map3k12
Name: mitogen-activated protein kinase kinase kinase 12
Synonyms: DLK, Zpk, MUK
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 26404
HGNC: HGNC:6851
Homologene: 4592
Ubxn11
Name: UBX domain protein 11
Synonyms: Soci, 4930506L07Rik, Ubxd5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67586
Homologene: 12159
Rcor1
Name: REST corepressor 1
Synonyms: D12Wsu95e, 6720480E22Rik, Rocr1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217864
Homologene: 32246
Etv6
Name: ets variant 6
Synonyms: Tel, translocation-ets-leukemia
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14011
HGNC: HGNC:3495
Homologene: 37560
Dkk2
Name: dickkopf WNT signaling pathway inhibitor 2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56811
HGNC: HGNC:2892
Homologene: 8681
Gpc6
Name: glypican 6
Synonyms: 6720429C22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 23888
HGNC: HGNC:4454
Homologene: 55922
Map2
Name: microtubule-associated protein 2
Synonyms: G1-397-34, Mtap2, repro4, MAP-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Cebpg
Name: CCAAT/enhancer binding protein gamma
Synonyms: GPE1-BP, Ig/EBP, Gpe1bp, C/EBPgamma
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12611
HGNC: HGNC:1837
Homologene: 1368
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, b2b414Clo, Dnchc2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, m152Asp, m407Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Zfp266
Name: zinc finger protein 266
Synonyms: 5730601F06Rik, 5330440G10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77519
Homologene: 105676
Lyrm4
Name: LYR motif containing 4
Synonyms: LOC380840
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 380840
VEGA: 13
Homologene: 41373
Pde4a
Name: phosphodiesterase 4A, cAMP specific
Synonyms: Dpde2, dunce, D9Ertd60e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18577
HGNC: HGNC:8780
Homologene: 4520
Tgm3
Name: transglutaminase 3, E polypeptide
Synonyms: we, TG E
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21818
Homologene: 20690
Fli1
Name: Friend leukemia integration 1
Synonyms: Sic1, EWSR2, SIC-1, Fli-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14247
HGNC: HGNC:3749
Homologene: 55624
Hyal4
Name: hyaluronoglucosaminidase 4
Synonyms: 4632428M18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 77042
HGNC: HGNC:5323
Homologene: 69117
Trim9
Name: tripartite motif-containing 9
Synonyms: C030048G07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 94090
VEGA: 12
Homologene: 9045
Snx7
Name: sorting nexin 7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76561
Homologene: 22941
Ttc8
Name: tetratricopeptide repeat domain 8
Synonyms: 0610012F22Rik, BBS8
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76260
Homologene: 14988
Prl8a6
Name: prolactin family 8, subfamily a, member 6
Synonyms: PLP-calpha, PLP-Ca, Prlpc, Prlpc1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19112
Pkd1l3
Name: polycystic kidney disease 1 like 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244646
Homologene: 14627
Cdh12
Name: cadherin 12
Synonyms: Br-cadherin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 215654
HGNC: HGNC:1751
Homologene: 37873
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: Naptb, beta3B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Arhgef5
Name: Rho guanine nucleotide exchange factor 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54324
Homologene: 66300
Vmn1r48
Name: vomeronasal 1 receptor 48
Synonyms: V1ra3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113845
Homologene: 137651
Zfp385c
Name: zinc finger protein 385C
Synonyms: A930006D11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 278304
Homologene: 65334
Ephx4
Name: epoxide hydrolase 4
Synonyms: LOC384214, Abhd7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384214
Homologene: 62402
Cdh4
Name: cadherin 4
Synonyms: R-cadherin, Rcad, R-Cadh
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12561
HGNC: HGNC:1763
Homologene: 48044
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
Cyp2c54
Name: cytochrome P450, family 2, subfamily c, polypeptide 54
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 404195
VEGA: 19
Homologene: 137231
Masp1
Name: MBL associated serine protease 1
Synonyms: Crarf
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17174
VEGA: 16
HGNC: HGNC:6901
Homologene: 88793
Vwa5b1
Name: von Willebrand factor A domain containing 5B1
Synonyms: 4931403E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75718
Homologene: 19431
Krt42
Name: keratin 42
Synonyms: ecat6, K17n, 2410039E07Rik, Ka22
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68239
Homologene: 107091
Ttc28
Name: tetratricopeptide repeat domain 28
Synonyms: 2310015L07Rik, TPRBK
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 209683
Homologene: 41023
Slc22a27
Name: solute carrier family 22, member 27
Synonyms: mOAT6 related protein, AB056442
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 171405
Homologene: 77136
Arhgef40
Name: Rho guanine nucleotide exchange factor 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268739
Homologene: 19560
Or2ag1b
Name: olfactory receptor family 2 subfamily AG member 1B
Synonyms: GA_x6K02T2PBJ9-9067220-9066273, MOR283-9, Olfr694
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258444
Homologene: 79345
Ces4a
Name: carboxylesterase 4A
Synonyms: Ces8
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234677
Homologene: 71949
Dyrk1b
Name: dual-specificity tyrosine phosphorylation regulated kinase 1b
Synonyms: Mirk
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13549
HGNC: HGNC:3092
Homologene: 31253
Ttll13
Name: tubulin tyrosine ligase-like family, member 13
Synonyms: 1700111A04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269954
Homologene: 136186
Ift56
Name: intraflagellar transport 56
Synonyms: hpy, hop, hydrocephalic-polydactyl, 9430097H08Rik, Ttc26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 264134
Homologene: 11786
Kcna3
Name: potassium voltage-gated channel, shaker-related subfamily, member 3
Synonyms: Kv1.3, Kca1-3, Mk-3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 16491
HGNC: HGNC:6221
Homologene: 128570
Vmn1r74
Name: vomeronasal 1 receptor 74
Synonyms: V1rg5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171240
Homologene: 110796
Zfp936
Name: zinc finger protein 936
Synonyms: Gm9272, EG435970, I1C0022H11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 668620
Redic1
Name: regulator of DNA class I crossover intermediates 1
Synonyms: Gm5807, CN725425
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545126
Uba1y
Name: ubiquitin-activating enzyme, Chr Y
Synonyms: Sby, A1s9Y-1, Ube1y1, Ube-2, Ube1y-1
Type: Gene
Species: Mouse
Chromosome: Y
NCBI: 22202
Homologene: 129435
Anxa10
Name: annexin A10
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 26359
HGNC: HGNC:534
Homologene: 21409
Or6b2
Name: olfactory receptor family 6 subfamily B member 2
Synonyms: Olfr1416, MOR103-3, GA_x6K02T2R7CC-81277975-81278913
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 259040
Homologene: 17472
Hdac1-ps
Name: histone deacetylase 1, pseudogene
Synonyms: Gm10093, EG15181
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15181
VEGA: 17
Zfp362
Name: zinc finger protein 362
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230761
Homologene: 77409
Mrap
Name: melanocortin 2 receptor accessory protein
Synonyms: 1110025G12Rik, C21ORF61
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 77037
HGNC: HGNC:1304
Homologene: 12669
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 66,421,773 bp
  • G to T, chromosome 1 at 92,480,605 bp
  • C to T, chromosome 2 at 130,041,970 bp
  • G to A, chromosome 2 at 179,860,194 bp
  • A to C, chromosome 3 at 56,019,415 bp
  • C to T, chromosome 3 at 107,036,568 bp
  • G to A, chromosome 3 at 117,829,636 bp
  • T to A, chromosome 3 at 132,175,126 bp
  • C to T, chromosome 4 at 128,786,015 bp
  • G to A, chromosome 4 at 134,126,264 bp
  • G to A, chromosome 4 at 138,586,569 bp
  • T to C, chromosome 5 at 107,413,561 bp
  • C to A, chromosome 5 at 111,277,025 bp
  • A to G, chromosome 6 at 24,756,191 bp
  • G to A, chromosome 6 at 38,401,144 bp
  • T to A, chromosome 6 at 43,273,298 bp
  • A to G, chromosome 6 at 90,036,568 bp
  • A to G, chromosome 6 at 134,266,458 bp
  • T to C, chromosome 7 at 11,847,441 bp
  • T to A, chromosome 7 at 28,185,117 bp
  • A to T, chromosome 7 at 35,050,777 bp
  • T to A, chromosome 7 at 43,190,043 bp
  • C to A, chromosome 7 at 44,505,355 bp
  • T to C, chromosome 7 at 80,250,182 bp
  • T to C, chromosome 7 at 81,484,912 bp
  • T to C, chromosome 7 at 106,689,189 bp
  • A to T, chromosome 7 at 135,708,760 bp
  • T to C, chromosome 8 at 62,096,782 bp
  • G to A, chromosome 8 at 105,146,698 bp
  • A to T, chromosome 8 at 109,614,614 bp
  • A to G, chromosome 8 at 120,229,822 bp
  • A to G, chromosome 9 at 7,131,855 bp
  • G to T, chromosome 9 at 20,499,599 bp
  • A to G, chromosome 9 at 21,204,970 bp
  • T to A, chromosome 9 at 32,429,925 bp
  • T to A, chromosome 9 at 122,368,155 bp
  • C to T, chromosome 10 at 19,860,994 bp
  • T to C, chromosome 11 at 51,601,848 bp
  • C to T, chromosome 11 at 100,269,716 bp
  • T to C, chromosome 11 at 100,632,759 bp
  • T to C, chromosome 12 at 70,346,639 bp
  • A to G, chromosome 12 at 71,067,137 bp
  • T to A, chromosome 12 at 98,961,476 bp
  • A to T, chromosome 12 at 111,108,888 bp
  • A to T, chromosome 13 at 27,437,047 bp
  • A to T, chromosome 13 at 36,117,124 bp
  • A to G, chromosome 13 at 94,418,142 bp
  • A to G, chromosome 14 at 51,997,368 bp
  • G to T, chromosome 14 at 117,951,217 bp
  • A to G, chromosome 15 at 21,583,786 bp
  • C to A, chromosome 15 at 91,240,763 bp
  • G to T, chromosome 15 at 102,500,629 bp
  • G to T, chromosome 15 at 102,500,630 bp
  • T to C, chromosome 16 at 23,513,834 bp
  • C to G, chromosome 16 at 90,749,305 bp
  • A to G, chromosome 17 at 78,492,660 bp
  • A to T, chromosome 19 at 7,926,579 bp
  • A to G, chromosome 19 at 40,070,259 bp
  • T to G, chromosome Y at 825,496 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6901 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044995-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.