Strain Name:
C57BL/6J-MtgxR8771Btlr/Mmmh
Stock Number:
068602-MU
Citation ID:
RRID:MMRRC_068602-MU
Other Names:
R8771 (G1)
Major Collection:

Strain Information

Ptprf
Name: protein tyrosine phosphatase receptor type F
Synonyms: RPTP-LAR, LAR
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19268
HGNC: HGNC:9670
Homologene: 20623
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: 1500002J22Rik, repro8, G1-419-52, eIF4GII, 4930523M17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Baz1b
Name: bromodomain adjacent to zinc finger domain, 1B
Synonyms: WSTF, Wbscr9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22385
HGNC: HGNC:961
Homologene: 22651
Dnmt3b
Name: DNA methyltransferase 3B
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13436
HGNC: HGNC:2979
Homologene: 56000
Ptpn2
Name: protein tyrosine phosphatase, non-receptor type 2
Synonyms: TC-PTP, Ptpt
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19255
HGNC: HGNC:9650
Homologene: 7497
Trip12
Name: thyroid hormone receptor interactor 12
Synonyms: Gtl6, 1110036I07Rik, 6720416K24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14897
Homologene: 44226
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: 2610036I19Rik, Acinus, 2610510L13Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56215
Homologene: 22853
Tmtc3
Name: transmembrane and tetratricopeptide repeat containing 3
Synonyms: mSmile, 9130014E20Rik, B130008E12Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237500
Homologene: 27616
D5Ertd579e
Name: DNA segment, Chr 5, ERATO Doi 579, expressed
Synonyms: 9030221A05Rik, A930018H20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320661
Homologene: 19716
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329252
Homologene: 49680
Zfp148
Name: zinc finger protein 148
Synonyms: ZBP-89, BFCOL1, BERF-1, 2210405J08Rik, beta enolase repressor factor 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 22661
VEGA: 16
Homologene: 8003
Nbeal1
Name: neurobeachin like 1
Synonyms: A530050O19Rik, 2310076G13Rik, ALS2CR17, A530083I02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269198
Homologene: 16453
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: crash, Adgrc1, Crsh, Scy
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Abca4
Name: ATP-binding cassette, sub-family A member 4
Synonyms: Rim protein, RmP, D430003I15Rik, Abc10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Or5p76
Name: olfactory receptor family 5 subfamily P member 76
Synonyms: GA_x6K02T2PBJ9-10853935-10852991, MOR204-8, Olfr502
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258734
Homologene: 72021
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329178
Homologene: 122243
Vmn2r61
Name: vomeronasal 2, receptor 61
Synonyms: Gprc2a-rs2, EG637873, Casr-rs2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637873
Homologene: 129683
Synpo2l
Name: synaptopodin 2-like
Synonyms: Chap, 1110054M18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 68760
Homologene: 23499
Tdrd7
Name: tudor domain containing 7
Synonyms: 5730495N10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100121
Homologene: 8618
Zfp775
Name: zinc finger protein 775
Synonyms: C130032F08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243372
Homologene: 37089
Or5m10b
Name: olfactory receptor family 5 subfamily M member 10B
Synonyms: MOR196-1, Olfr1022, GA_x6K02T2Q125-47347069-47348016
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258582
Homologene: 128086
Mfsd13a
Name: major facilitator superfamily domain containing 13a
Synonyms: 4930538D17Rik, Tmem180, 4930449A08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 75146
Homologene: 12592
Myo1c
Name: myosin IC
Synonyms: mm1beta, C80397, myr2, myosin-Ibeta
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224833
Homologene: 138294
Mroh5
Name: maestro heat-like repeat family member 5
Synonyms: LOC268816, Gm628
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 268816
Tmem132c
Name: transmembrane protein 132C
Synonyms: 4632425D07Rik, 2810482M11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208213
Homologene: 76567
Ces5a
Name: carboxylesterase 5A
Synonyms: cauxin, LOC244598, 1700122C07Rik, Ces7, 1700081L16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67935
Homologene: 74305
Serpina3m
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3M
Synonyms: MMCM7, Spi-2l, contrapsin-like, Spi2-rs1, alpha-1 antiproteinase, 3e46, antitrypsin, Spi-2rs1, Spi2.4, MMSPi2.4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20717
HGNC: HGNC:16
Homologene: 111129
Krt87
Name: keratin 87
Synonyms: Krt2-25, Krt83
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 406219
VEGA: 15
Homologene: 133804
Minar2
Name: membrane integral NOTCH2 associated receptor 2
Synonyms: A730017C20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225583
Homologene: 18350
Ano5
Name: anoctamin 5
Synonyms: Tmem16e, Gdd1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233246
Homologene: 100071
Sorcs2
Name: sortilin-related VPS10 domain containing receptor 2
Synonyms: VPS10 domain receptor protein
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 81840
Homologene: 56899
Mrc2
Name: mannose receptor, C type 2
Synonyms: uPARAP, novel lectin, Endo180
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17534
Homologene: 4408
Hhatl
Name: hedgehog acyltransferase-like
Synonyms: Mitsugumin 56, Mg56, 1110011D13Rik, Gup1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74770
VEGA: 9
Homologene: 19287
Etnppl
Name: ethanolamine phosphate phospholyase
Synonyms: Agxt2l1, 1300019H02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71760
Homologene: 69440
Vmn2r16
Name: vomeronasal 2, receptor 16
Synonyms: EG384220
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384220
Homologene: 104825
Ttll6
Name: tubulin tyrosine ligase-like family, member 6
Synonyms: D11Moh44e, 4932418K24Rik, D11Moh43e, t8130b59
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237930
Homologene: 18229
Sprr1a
Name: small proline-rich protein 1A
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20753
Homologene: 105698
Or4c12
Name: olfactory receptor family 4 subfamily C member 12
Synonyms: Olfr1259, GA_x6K02T2Q125-51376062-51375133, MOR232-9
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258338
Homologene: 128115
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 627569
Homologene: 129606
Lrriq3
Name: leucine-rich repeats and IQ motif containing 3
Synonyms: 4930438B07Rik, 4930511J15Rik, 4933403H06Rik, Lrrc44
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74435
Homologene: 23668
Or5aq6
Name: olfactory receptor family 5 subfamily AQ member 6
Synonyms: GA_x6K02T2Q125-48586461-48585523, MOR172-5, Olfr1109
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258762
Homologene: 86672
Cdh22
Name: cadherin 22
Synonyms: PB-cadherin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 104010
Homologene: 23148
Prl7a1
Name: prolactin family 7, subfamily a, member 1
Synonyms: PLP-G, Prlpe, PLP-E, Prlpg
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19113
Homologene: 136279
Sptssa
Name: serine palmitoyltransferase, small subunit A
Synonyms: 1110002B05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104725
VEGA: 12
Homologene: 15889
Igkv5-37
Name: immunoglobulin kappa variable 5-37
Synonyms: IgVk 23-37, LOC384417
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 384417
Raet1e
Name: retinoic acid early transcript 1E
Synonyms: Rae-1 epsilon
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 379043
Homologene: 134115
Vmn1r142
Name: vomeronasal 1 receptor 142
Synonyms: Gm8647
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 667464
Homologene: 104166
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 60,261,584 bp
  • A to G, chromosome 1 at 66,646,395 bp
  • A to T, chromosome 1 at 84,743,297 bp
  • A to T, chromosome 1 at 135,005,691 bp
  • T to G, chromosome 2 at 85,869,368 bp
  • T to C, chromosome 2 at 87,092,950 bp
  • T to C, chromosome 2 at 89,943,221 bp
  • C to T, chromosome 2 at 153,662,814 bp
  • A to T, chromosome 2 at 165,146,769 bp
  • T to A, chromosome 3 at 92,484,682 bp
  • T to C, chromosome 3 at 122,086,671 bp
  • T to A, chromosome 3 at 130,620,375 bp
  • G to A, chromosome 3 at 155,193,633 bp
  • T to C, chromosome 4 at 46,010,800 bp
  • A to G, chromosome 4 at 118,211,790 bp
  • C to T, chromosome 4 at 138,180,537 bp
  • T to C, chromosome 5 at 36,031,280 bp
  • T to A, chromosome 5 at 36,604,596 bp
  • T to G, chromosome 5 at 109,092,086 bp
  • C to T, chromosome 5 at 109,340,365 bp
  • C to T, chromosome 5 at 127,360,128 bp
  • T to A, chromosome 5 at 135,244,297 bp
  • A to T, chromosome 6 at 48,619,972 bp
  • A to G, chromosome 6 at 69,963,439 bp
  • T to C, chromosome 7 at 22,163,312 bp
  • C to A, chromosome 7 at 42,266,770 bp
  • C to A, chromosome 7 at 51,566,347 bp
  • C to T, chromosome 7 at 51,570,299 bp
  • T to A, chromosome 7 at 108,523,425 bp
  • A to G, chromosome 8 at 93,528,621 bp
  • G to A, chromosome 9 at 121,788,710 bp
  • G to T, chromosome 10 at 22,181,142 bp
  • A to G, chromosome 10 at 100,450,318 bp
  • A to G, chromosome 11 at 75,665,883 bp
  • A to G, chromosome 11 at 96,151,936 bp
  • A to G, chromosome 11 at 105,349,770 bp
  • A to G, chromosome 12 at 54,656,426 bp
  • A to G, chromosome 12 at 104,391,582 bp
  • A to T, chromosome 13 at 27,635,828 bp
  • A to G, chromosome 14 at 20,660,423 bp
  • T to C, chromosome 14 at 54,643,039 bp
  • A to T, chromosome 15 at 73,821,354 bp
  • A to T, chromosome 15 at 85,903,974 bp
  • A to G, chromosome 15 at 101,487,898 bp
  • A to G, chromosome 16 at 33,497,286 bp
  • T to C, chromosome 17 at 47,466,758 bp
  • T to C, chromosome 18 at 59,066,980 bp
  • G to T, chromosome 18 at 67,672,589 bp
  • T to C, chromosome 19 at 46,372,229 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8771 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068602-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.