Strain Name:
C57BL/6J-MtgxR9436Btlr/Mmmh
Stock Number:
069240-MU
Citation ID:
RRID:MMRRC_069240-MU
Other Names:
R9436 (G1)
Major Collection:

Strain Information

Sp4
Name: trans-acting transcription factor 4
Synonyms: HF-1b, HF1-b, 5730497N03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20688
VEGA: 12
Homologene: 2341
Mrtfb
Name: myocardin related transcription factor B
Synonyms: Mrtfb, Mkl2, MRTF-B, Gt4-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239719
Homologene: 40917
Ndrg3
Name: N-myc downstream regulated gene 3
Synonyms: Ndr3, 4833415O14Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 29812
Homologene: 40903
Npy5r
Name: neuropeptide Y receptor Y5
Synonyms: Y5R
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18168
HGNC: HGNC:7958
Homologene: 21241
Add1
Name: adducin 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11518
HGNC: HGNC:243
Homologene: 22758
Rps6ka1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: Rsk1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20111
Homologene: 55703
Rnmt
Name: RNA (guanine-7-) methyltransferase
Synonyms: 2610002P10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67897
Homologene: 2816
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224020
HGNC: HGNC:8983
Homologene: 11171
Ccdc93
Name: coiled-coil domain containing 93
Synonyms: 9230102M16Rik, 4633402D15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70829
Homologene: 10393
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, 2610021O03Rik, Apc1, Mcpr
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17222
Homologene: 7414
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: 9930018I23Rik, MAP1C, Swl, Dnec1, Loa, Dnchc1, dynein heavy chain, retrograde transport
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Hnrnph3
Name: heterogeneous nuclear ribonucleoprotein H3
Synonyms: Hnrph3, hnRNP 2H9
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432467
HGNC: HGNC:5043
Homologene: 11012
Chrm5
Name: cholinergic receptor, muscarinic 5
Synonyms: M5R, muscarinic acetylcholine receptor 5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 213788
HGNC: HGNC:1954
Homologene: 22697
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Rbp-3, Irbp
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Katnal1
Name: katanin p60 subunit A-like 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231912
Homologene: 12942
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 667663
HGNC: HGNC:7601
Homologene: 49486
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: LOC381311, Gm980, A230079K17Rik, Dnahc14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329178
Homologene: 122243
Slc7a1
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
Synonyms: Atrc1, Cat1, Rec-1, 4831426K01Rik, Rev-1, mCAT-1, Atrc-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11987
Homologene: 20658
Nlrp14
Name: NLR family, pyrin domain containing 14
Synonyms: GC-LRR, 4921520L01Rik, Nalp14, Nalp-iota
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76858
Homologene: 18531
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56552
Homologene: 135915
Adamts2
Name: ADAM metallopeptidase with thrombospondin type 1 motif 2
Synonyms: a disintegrin and metalloproteinase with thrombospondin repeats, procollagen N-proteinase, ADAM-TS2, hPCPNI
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216725
HGNC: HGNC:218
Homologene: 8597
Ankhd1
Name: ankyrin repeat and KH domain containing 1
Synonyms: 9130019P20Rik, 4933432B13Rik, A530027J04Rik, 1110004O12Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 108857
Homologene: 87006
Spag16
Name: sperm associated antigen 16
Synonyms: 4921511D23Rik, 4930585K05Rik, 4930524F24Rik, Pf20, Wdr29
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66722
Homologene: 11572
Snx19
Name: sorting nexin 19
Synonyms: 3526401K03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102607
VEGA: 9
Homologene: 8846
Hinfp
Name: histone H4 transcription factor
Synonyms: DKFZp434F162, Mizf
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102423
VEGA: 9
Homologene: 9174
Tmf1
Name: TATA element modulatory factor 1
Synonyms: LOC232286, 7030402D04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232286
Homologene: 133801
Ttc7
Name: tetratricopeptide repeat domain 7
Synonyms: fsn, 1110035E02Rik, 1700007L07Rik, hea
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 225049
Homologene: 12515
Whamm
Name: WAS protein homolog associated with actin, golgi membranes and microtubules
Synonyms: Whdc1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434204
Homologene: 45851
Krt17
Name: keratin 17
Synonyms: Krt1-17, K17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16667
HGNC: HGNC:6427
Homologene: 363
Ifi44
Name: interferon-induced protein 44
Synonyms: MTAP44, p44, A430056A10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99899
Homologene: 4683
Eme1
Name: essential meiotic structure-specific endonuclease 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268465
Homologene: 16123
Smr2l
Name: submaxillary gland androgen regulated protein 2 like
Synonyms: Gm7714
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665615
Tchp
Name: trichoplein, keratin filament binding
Synonyms: A930031F18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77832
Homologene: 12686
A1cf
Name: APOBEC1 complementation factor
Synonyms: apobec-1 complementation factor, 1810073H04Rik, ACF
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69865
VEGA: 19
Homologene: 16363
Zfp974
Name: zinc finger protein 974
Synonyms: 1700049G17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73430
Stk36
Name: serine/threonine kinase 36
Synonyms: 1700112N14Rik, Fused
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269209
Homologene: 49432
Zfp184
Name: zinc finger protein 184 (Kruppel-like)
Synonyms: 4930500C15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 193452
Homologene: 113602
Alpk1
Name: alpha-kinase 1
Synonyms: 8430410J10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71481
Homologene: 11849
Tmem132b
Name: transmembrane protein 132B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208151
Homologene: 28135
Tat
Name: tyrosine aminotransferase
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234724
Homologene: 37293
Smyd4
Name: SET and MYND domain containing 4
Synonyms: G430029E23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319822
Homologene: 35098
Nfkbib
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
Synonyms: IKappaBbeta, IkB
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18036
HGNC: HGNC:7798
Homologene: 37631
Or6c75
Name: olfactory receptor family 6 subfamily C member 75
Synonyms: Olfr790, GA_x6K02T2PULF-11179777-11180721, MOR112-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258935
Homologene: 74101
Clxn
Name: calaxin
Synonyms: 5430404L10Rik, Efcab1, 4930449A16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66793
VEGA: 16
Homologene: 11608
Kcnk12
Name: potassium channel, subfamily K, member 12
Synonyms: mntk1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210741
VEGA: 17
HGNC: HGNC:6274
Homologene: 11107
Rpl3l
Name: ribosomal protein L3-like
Synonyms: 1110057H16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66211
Homologene: 68434
Pcdhga3
Name: protocadherin gamma subfamily A, 3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93711
HGNC: HGNC:8701
Homologene: 75100
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to G, chromosome 1 at 66,693,805 bp (GRCm38)
  • C to T, chromosome 1 at 69,853,380 bp (GRCm38)
  • A to G, chromosome 1 at 74,611,113 bp (GRCm38)
  • C to T, chromosome 1 at 121,441,855 bp (GRCm38)
  • A to C, chromosome 1 at 181,680,783 bp (GRCm38)
  • T to A, chromosome 2 at 22,407,424 bp (GRCm38)
  • T to C, chromosome 2 at 76,941,919 bp (GRCm38)
  • T to C, chromosome 2 at 112,479,479 bp (GRCm38)
  • T to C, chromosome 2 at 128,676,125 bp (GRCm38)
  • C to A, chromosome 2 at 156,940,356 bp (GRCm38)
  • A to G, chromosome 3 at 127,685,275 bp (GRCm38)
  • T to C, chromosome 3 at 151,749,249 bp (GRCm38)
  • A to T, chromosome 4 at 133,848,652 bp (GRCm38)
  • A to T, chromosome 5 at 34,605,929 bp (GRCm38)
  • A to G, chromosome 5 at 88,282,398 bp (GRCm38)
  • G to T, chromosome 5 at 114,709,385 bp (GRCm38)
  • A to G, chromosome 5 at 125,698,569 bp (GRCm38)
  • A to T, chromosome 5 at 148,333,920 bp (GRCm38)
  • A to T, chromosome 5 at 148,878,951 bp (GRCm38)
  • T to C, chromosome 6 at 97,176,656 bp (GRCm38)
  • T to C, chromosome 6 at 124,025,867 bp (GRCm38)
  • A to T, chromosome 7 at 27,911,669 bp (GRCm38)
  • C to A, chromosome 7 at 28,766,375 bp (GRCm38)
  • G to T, chromosome 7 at 81,571,315 bp (GRCm38)
  • T to C, chromosome 7 at 107,181,899 bp (GRCm38)
  • A to G, chromosome 8 at 66,680,831 bp (GRCm38)
  • G to T, chromosome 8 at 109,991,860 bp (GRCm38)
  • A to G, chromosome 9 at 30,463,306 bp (GRCm38)
  • A to T, chromosome 9 at 44,297,979 bp (GRCm38)
  • T to A, chromosome 10 at 63,018,848 bp (GRCm38)
  • T to C, chromosome 10 at 129,501,100 bp (GRCm38)
  • G to T, chromosome 11 at 50,803,680 bp (GRCm38)
  • T to A, chromosome 11 at 75,402,191 bp (GRCm38)
  • G to A, chromosome 11 at 94,647,681 bp (GRCm38)
  • T to A, chromosome 11 at 100,257,499 bp (GRCm38)
  • T to C, chromosome 12 at 110,616,541 bp (GRCm38)
  • T to C, chromosome 12 at 118,238,265 bp (GRCm38)
  • A to G, chromosome 13 at 21,949,728 bp (GRCm38)
  • A to G, chromosome 14 at 33,955,277 bp (GRCm38)
  • T to A, chromosome 16 at 13,405,287 bp (GRCm38)
  • T to A, chromosome 16 at 14,917,677 bp (GRCm38)
  • T to A, chromosome 16 at 17,307,806 bp (GRCm38)
  • A to T, chromosome 17 at 24,728,326 bp (GRCm38)
  • T to C, chromosome 17 at 87,292,892 bp (GRCm38)
  • C to A, chromosome 17 at 87,797,452 bp (GRCm38)
  • C to A, chromosome 18 at 36,560,988 bp (GRCm38)
  • T to A, chromosome 18 at 36,641,601 bp (GRCm38)
  • G to A, chromosome 18 at 37,675,091 bp (GRCm38)
  • T to A, chromosome 18 at 68,309,339 bp (GRCm38)
  • A to G, chromosome 19 at 31,932,575 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9436 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069240-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.