Strain Name:
C57BL/6J-MtgxR9602Btlr/Mmmh
Stock Number:
069395-MU
Citation ID:
RRID:MMRRC_069395-MU
Other Names:
R9602 (G1)
Major Collection:

Strain Information

Hcn2
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2
Synonyms: HAC1, trls
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15166
HGNC: HGNC:4846
Homologene: 31022
Epb41l1
Name: erythrocyte membrane protein band 4.1 like 1
Synonyms: 4.1N, Epb4.1l1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13821
HGNC: HGNC:3378
Homologene: 8126
Spen
Name: spen family transcription repressor
Synonyms: Mint
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56381
Homologene: 124461
Mov10
Name: Mov10 RISC complex RNA helicase
Synonyms: Mov-10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 17454
HGNC: HGNC:7200
Homologene: 10365
Arhgap39
Name: Rho GTPase activating protein 39
Synonyms: D15Wsu169e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223666
Homologene: 27825
Arhgef12
Name: Rho guanine nucleotide exchange factor 12
Synonyms: 2310014B11Rik, LARG
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69632
VEGA: 9
Homologene: 9088
Mllt10
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
Synonyms: Af10, D630001B22Rik, B130021D15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17354
Homologene: 20973
Cenpp
Name: centromere protein P
Synonyms: 4921518G09Rik, 1700022C02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66336
VEGA: 13
Homologene: 23543
Rbm5
Name: RNA binding motif protein 5
Synonyms: D030069N10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83486
HGNC: HGNC:9902
Homologene: 21177
Gtf2h1
Name: general transcription factor II H, polypeptide 1
Synonyms: 62kDa, p62
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14884
HGNC: HGNC:4655
Homologene: 3885
Prr11
Name: proline rich 11
Synonyms: B930067F20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 270906
Homologene: 10123
Socs7
Name: suppressor of cytokine signaling 7
Synonyms: Nap4, 2310063P06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192157
Homologene: 16331
Secisbp2l
Name: SECIS binding protein 2-like
Synonyms: 3110001I20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70354
Homologene: 18923
Rnf114
Name: ring finger protein 114
Synonyms: Zfp313, 1110008J21Rik, Znf228
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 81018
Homologene: 10265
Bcar1
Name: breast cancer anti-estrogen resistance 1
Synonyms: Crkas, Cas, p130Cas
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12927
HGNC: HGNC:971
Homologene: 7674
Rreb1
Name: ras responsive element binding protein 1
Synonyms: 1110037N09Rik, B930013M22Rik, sao
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68750
Homologene: 2218
Rasa3
Name: RAS p21 protein activator 3
Synonyms: R-Ras gap, scat, GAPIII activator 3, GAPIII, Ras GTPase-activating protein III, hlb381
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19414
Homologene: 7217
Fmnl2
Name: formin-like 2
Synonyms: man, 5430425K04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71409
Homologene: 70871
Zfp655
Name: zinc finger protein 655
Synonyms: 2700038I16Rik, 9030409O18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72611
Homologene: 12473
Klhl2
Name: kelch-like 2, Mayven
Synonyms: ABP-KELCH, Mav, 6030411N21Rik, 8530402H02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 77113
HGNC: HGNC:6353
Homologene: 21416
Smg5
Name: SMG5 nonsense mediated mRNA decay factor
Synonyms: Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229512
Homologene: 9095
Wnt5a
Name: wingless-type MMTV integration site family, member 5A
Synonyms: Wnt-5a, 8030457G12Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22418
Homologene: 20720
Tek
Name: TEK receptor tyrosine kinase
Synonyms: tie-2, Hyk, Cd202b, Tie2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21687
Homologene: 397
Abca3
Name: ATP-binding cassette, sub-family A member 3
Synonyms: Abc3, ABC-C, 1810036E22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Bbs1
Name: Bardet-Biedl syndrome 1
Synonyms: D19Ertd609e
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 52028
VEGA: 19
HGNC: HGNC:966
Homologene: 11641
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Brinp3
Name: bone morphogenetic protein/retinoic acid inducible neural specific 3
Synonyms: Fam5c, B830045N13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 215378
Homologene: 17786
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: 2300002I04Rik, MUC5, MUC9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Col14a1
Name: collagen, type XIV, alpha 1
Synonyms: 5730412L22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12818
HGNC: HGNC:2191
Homologene: 18741
Vmn2r88
Name: vomeronasal 2, receptor 88
Synonyms: V2r13, V2r3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 669149
Homologene: 129606
Rmdn2
Name: regulator of microtubule dynamics 2
Synonyms: Fam82a1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381110
VEGA: 17
Homologene: 71930
Gata3
Name: GATA binding protein 3
Synonyms: jal, Gata-3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14462
HGNC: HGNC:4172
Homologene: 1550
Zpr1
Name: ZPR1 zinc finger
Synonyms: Zfp259, ZPR1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22687
Homologene: 2900
Vmn2r82
Name: vomeronasal 2, receptor 82
Synonyms: EG624845
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 624845
Homologene: 83483
Adam5
Name: a disintegrin and metallopeptidase domain 5
Synonyms: tMDCII
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11499
HGNC: HGNC:212
Homologene: 49138
Fbxw10
Name: F-box and WD-40 domain protein 10
Synonyms: SM25H2, SM2SH2, Fbw10
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 213980
Homologene: 32757
Myo15b
Name: myosin XVB
Synonyms: LOC217328, E330039G21Rik, LOC380737
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217328
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330222
Homologene: 27395
Cdh20
Name: cadherin 20
Synonyms: Cdh7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23836
HGNC: HGNC:1760
Homologene: 8015
Yipf5
Name: Yip1 domain family, member 5
Synonyms: Yip1a, 2610311I19Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67180
VEGA: 18
Homologene: 56969
Vmn2r101
Name: vomeronasal 2, receptor 101
Synonyms: EG627576
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627576
Homologene: 115024
Prx
Name: periaxin
Synonyms: L-Periaxin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19153
Homologene: 76542
Nudt7
Name: nudix hydrolase 7
Synonyms: 1300007B24Rik, 2210404C19Rik, nudix (nucleoside diphosphate linked moiety X)-type motif 7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67528
HGNC: HGNC:8054
Homologene: 41564
Ugt2b34
Name: UDP glucuronosyltransferase 2 family, polypeptide B34
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100727
Homologene: 117389
Mn1
Name: meningioma 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433938
HGNC: HGNC:7180
Homologene: 37620
Kctd20
Name: potassium channel tetramerisation domain containing 20
Synonyms: D17Ertd562e, 2410004N11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66989
Homologene: 12063
Pabpn1l
Name: poly(A)binding protein nuclear 1-like
Synonyms: LOC382035, ePABP2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382035
Homologene: 19736
Slc22a6
Name: solute carrier family 22 (organic anion transporter), member 6
Synonyms: mOat1, Oat1, Orctl1, NKT
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18399
VEGA: 19
Homologene: 16813
Upk3a
Name: uroplakin 3A
Synonyms: 1110017C07Rik, Upk3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22270
VEGA: 15
Homologene: 5066
Slc14a1
Name: solute carrier family 14 (urea transporter), member 1
Synonyms: UT-B, 3021401A05Rik, 2610507K20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 108052
Homologene: 9285
Cox6a1
Name: cytochrome c oxidase subunit 6A1
Synonyms: subunit VIaL (liver-type), VIaL
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12861
HGNC: HGNC:2277
Homologene: 3219
4930563M21Rik
Name: RIKEN cDNA 4930563M21 gene
Synonyms: Rfpl3s
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75258
VEGA: 9
Homologene: 138467
Ptcd1
Name: pentatricopeptide repeat domain 1
Synonyms: 1110069M14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71799
Homologene: 33161
Gpr31b
Name: G protein-coupled receptor 31, D17Leh66b region
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 436440
VEGA: 17
HGNC: HGNC:4486
Homologene: 48337
Or6c5b
Name: olfactory receptor family 6 subfamily C member 5B
Synonyms: Olfr785-ps1, GA_x6K02T2PULF-11089673-11090600, EG546488, MOR111-8P, MOR111-14_i, Olfr785, Gm44444
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 546488
Gm14406
Name: predicted gene 14406
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100504328
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 90,803,775 bp (GRCm38)
  • A to T, chromosome 1 at 104,941,098 bp (GRCm38)
  • C to T, chromosome 1 at 146,746,496 bp (GRCm38)
  • T to A, chromosome 2 at 9,858,486 bp (GRCm38)
  • T to C, chromosome 2 at 18,207,039 bp (GRCm38)
  • T to C, chromosome 2 at 53,123,575 bp (GRCm38)
  • C to T, chromosome 2 at 76,885,013 bp (GRCm38)
  • A to T, chromosome 2 at 125,767,436 bp (GRCm38)
  • G to T, chromosome 2 at 156,525,148 bp (GRCm38)
  • T to A, chromosome 2 at 167,511,242 bp (GRCm38)
  • C to T, chromosome 2 at 177,569,235 bp (GRCm38)
  • T to C, chromosome 3 at 88,342,907 bp (GRCm38)
  • A to T, chromosome 3 at 104,800,968 bp (GRCm38)
  • C to G, chromosome 4 at 94,827,731 bp (GRCm38)
  • T to C, chromosome 4 at 141,477,872 bp (GRCm38)
  • T to C, chromosome 5 at 86,906,304 bp (GRCm38)
  • A to T, chromosome 5 at 111,417,583 bp (GRCm38)
  • G to A, chromosome 5 at 115,348,875 bp (GRCm38)
  • A to T, chromosome 5 at 142,085,598 bp (GRCm38)
  • A to G, chromosome 5 at 145,159,638 bp (GRCm38)
  • T to A, chromosome 5 at 145,244,663 bp (GRCm38)
  • T to A, chromosome 7 at 27,519,020 bp (GRCm38)
  • T to A, chromosome 7 at 46,806,795 bp (GRCm38)
  • G to T, chromosome 7 at 141,863,474 bp (GRCm38)
  • T to C, chromosome 8 at 13,631,844 bp (GRCm38)
  • T to C, chromosome 8 at 24,813,386 bp (GRCm38)
  • A to T, chromosome 8 at 64,752,662 bp (GRCm38)
  • C to T, chromosome 8 at 111,713,866 bp (GRCm38)
  • T to C, chromosome 8 at 114,151,759 bp (GRCm38)
  • T to A, chromosome 8 at 122,620,362 bp (GRCm38)
  • A to G, chromosome 9 at 42,984,380 bp (GRCm38)
  • A to G, chromosome 9 at 46,273,365 bp (GRCm38)
  • G to A, chromosome 9 at 56,002,977 bp (GRCm38)
  • A to G, chromosome 9 at 107,751,953 bp (GRCm38)
  • A to G, chromosome 10 at 79,379,046 bp (GRCm38)
  • A to G, chromosome 10 at 79,726,294 bp (GRCm38)
  • A to T, chromosome 10 at 129,409,933 bp (GRCm38)
  • A to G, chromosome 11 at 59,090,559 bp (GRCm38)
  • G to T, chromosome 11 at 62,859,956 bp (GRCm38)
  • C to T, chromosome 11 at 87,097,172 bp (GRCm38)
  • A to G, chromosome 11 at 97,377,011 bp (GRCm38)
  • G to A, chromosome 11 at 115,878,443 bp (GRCm38)
  • T to C, chromosome 13 at 37,930,501 bp (GRCm38)
  • T to C, chromosome 13 at 49,647,573 bp (GRCm38)
  • C to A, chromosome 14 at 28,518,338 bp (GRCm38)
  • T to A, chromosome 14 at 51,413,732 bp (GRCm38)
  • C to A, chromosome 15 at 55,487,949 bp (GRCm38)
  • A to C, chromosome 15 at 76,726,754 bp (GRCm38)
  • C to T, chromosome 15 at 85,021,263 bp (GRCm38)
  • C to T, chromosome 17 at 13,051,884 bp (GRCm38)
  • T to A, chromosome 17 at 19,611,518 bp (GRCm38)
  • T to C, chromosome 17 at 24,398,404 bp (GRCm38)
  • T to C, chromosome 17 at 28,961,468 bp (GRCm38)
  • G to A, chromosome 17 at 79,668,011 bp (GRCm38)
  • T to C, chromosome 18 at 40,212,081 bp (GRCm38)
  • C to A, chromosome 18 at 78,109,592 bp (GRCm38)
  • G to A, chromosome 19 at 4,891,055 bp (GRCm38)
  • G to T, chromosome 19 at 8,621,196 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9602 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069395-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.