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Strain Name:
C57BL/6J-MtgxR9618Btlr/Mmmh
Stock Number:
069411-MU
Citation ID:
RRID:MMRRC_069411-MU
Other Names:
R9618 (G1)
Major Collection:

Strain Information

Pygb
Name: brain glycogen phosphorylase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110078
HGNC: HGNC:9723
Homologene: 100930
Pcnt
Name: pericentrin (kendrin)
Synonyms: Pcnt2, m275Asp, m239Asp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18541
VEGA: 10
Eefsec
Name: eukaryotic elongation factor, selenocysteine-tRNA-specific
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 65967
Homologene: 11073
Zc3h13
Name: zinc finger CCCH type containing 13
Synonyms: C87618, 4930570G11Rik, 2600010B19Rik, 3110050K21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67302
VEGA: 14
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108989
Homologene: 37753
Ergic1
Name: endoplasmic reticulum-golgi intermediate compartment 1
Synonyms: 1200007D18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67458
Homologene: 41667
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, XAP8, Hbxap, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 3,670,978 bp (GRCm38)
  • T to C, chromosome 1 at 34,536,479 bp (GRCm38)
  • G to A, chromosome 1 at 63,062,183 bp (GRCm38)
  • A to G, chromosome 1 at 67,157,816 bp (GRCm38)
  • G to T, chromosome 1 at 150,446,228 bp (GRCm38)
  • G to A, chromosome 1 at 157,462,008 bp (GRCm38)
  • A to T, chromosome 2 at 29,783,334 bp (GRCm38)
  • A to T, chromosome 2 at 89,977,999 bp (GRCm38)
  • T to A, chromosome 2 at 107,296,029 bp (GRCm38)
  • G to T, chromosome 2 at 127,510,892 bp (GRCm38)
  • T to C, chromosome 2 at 140,159,794 bp (GRCm38)
  • C to T, chromosome 2 at 150,815,088 bp (GRCm38)
  • T to A, chromosome 3 at 59,115,830 bp (GRCm38)
  • T to A, chromosome 3 at 64,271,303 bp (GRCm38)
  • C to T, chromosome 3 at 68,870,069 bp (GRCm38)
  • C to A, chromosome 4 at 73,950,697 bp (GRCm38)
  • A to T, chromosome 4 at 96,525,848 bp (GRCm38)
  • T to C, chromosome 4 at 98,765,495 bp (GRCm38)
  • A to T, chromosome 4 at 134,055,654 bp (GRCm38)
  • T to A, chromosome 4 at 147,945,416 bp (GRCm38)
  • G to A, chromosome 5 at 30,134,167 bp (GRCm38)
  • A to G, chromosome 5 at 76,856,770 bp (GRCm38)
  • T to G, chromosome 6 at 9,247,108 bp (GRCm38)
  • T to A, chromosome 6 at 22,297,892 bp (GRCm38)
  • G to T, chromosome 6 at 22,297,893 bp (GRCm38)
  • T to C, chromosome 6 at 88,297,699 bp (GRCm38)
  • A to T, chromosome 6 at 138,055,781 bp (GRCm38)
  • A to G, chromosome 7 at 15,555,699 bp (GRCm38)
  • G to GACGGCGGCC, chromosome 7 at 97,579,909 bp (GRCm38)
  • A to G, chromosome 8 at 12,984,320 bp (GRCm38)
  • A to G, chromosome 8 at 33,572,369 bp (GRCm38)
  • T to C, chromosome 9 at 13,796,019 bp (GRCm38)
  • G to A, chromosome 9 at 20,260,343 bp (GRCm38)
  • T to C, chromosome 9 at 62,850,829 bp (GRCm38)
  • T to C, chromosome 9 at 122,856,723 bp (GRCm38)
  • A to C, chromosome 10 at 41,327,631 bp (GRCm38)
  • A to G, chromosome 10 at 76,352,960 bp (GRCm38)
  • T to C, chromosome 11 at 8,961,420 bp (GRCm38)
  • A to T, chromosome 11 at 33,554,342 bp (GRCm38)
  • T to A, chromosome 11 at 69,839,384 bp (GRCm38)
  • T to C, chromosome 11 at 73,120,345 bp (GRCm38)
  • A to T, chromosome 14 at 50,320,303 bp (GRCm38)
  • G to T, chromosome 14 at 75,330,102 bp (GRCm38)
  • A to T, chromosome 16 at 4,849,554 bp (GRCm38)
  • T to G, chromosome 16 at 20,733,628 bp (GRCm38)
  • T to A, chromosome 17 at 7,771,481 bp (GRCm38)
  • A to T, chromosome 17 at 19,522,321 bp (GRCm38)
  • T to C, chromosome 17 at 20,776,783 bp (GRCm38)
  • G to A, chromosome 17 at 26,608,645 bp (GRCm38)
  • GGGGTGGGCATAGATCCTGAGGCAGAGCTGGATGCAGTGGTGGTCAGGGTGGG to GGGGTGGG, chromosome 17 at 35,622,043 bp (GRCm38)
  • T to A, chromosome 17 at 71,750,822 bp (GRCm38)
  • T to C, chromosome 17 at 78,491,685 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9618 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069411-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.