Strain Name:
C57BL/6J-MtgxR9683Btlr/Mmmh
Stock Number:
069476-MU
Citation ID:
RRID:MMRRC_069476-MU
Other Names:
R9683 (G1)
Major Collection:

Strain Information

Npl
Name: N-acetylneuraminate pyruvate lyase
Synonyms: 0610033B02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74091
Homologene: 12533
Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: 4432411E13Rik, Edd1, Edd
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70790
VEGA: 15
Homologene: 9295
Bicral
Name: BRD4 interacting chromatin remodeling complex associated protein like
Synonyms: Gltscr1l, BC032203
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210982
VEGA: 17
Homologene: 19366
Cnot6
Name: CCR4-NOT transcription complex, subunit 6
Synonyms: A230103N10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104625
Homologene: 69187
Anln
Name: anillin, actin binding protein
Synonyms: Scraps, 2900037I21Rik, 1110037A17Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68743
VEGA: 9
Homologene: 41281
Ankrd11
Name: ankyrin repeat domain 11
Synonyms: Yod, 9530048I21Rik, 3010027A04Rik, 2410104C19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 77087
Homologene: 69134
Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
Synonyms: D10Ertd625e, 1200015F06Rik, 5730577I22Rik, Mypt1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17931
VEGA: 10
HGNC: HGNC:7618
Homologene: 1855
Top2a
Name: topoisomerase (DNA) II alpha
Synonyms: DNA Topoisomerase II alpha, Top-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21973
Homologene: 830
Heatr1
Name: HEAT repeat containing 1
Synonyms: B130016L12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 217995
VEGA: 13
Homologene: 34562
Sgk1
Name: serum/glucocorticoid regulated kinase 1
Synonyms: Sgk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20393
Homologene: 48364
Spag9
Name: sperm associated antigen 9
Synonyms: 4733401I23Rik, syd1, 4831406C20Rik, Mapk8ip4, JIP4, 3110018C07Rik, JLP
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70834
Homologene: 2954
Mindy1
Name: MINDY lysine 48 deubiquitinase 1
Synonyms: 1810005H09Rik, NF-E2 inducible protein, 4930504E06Rik, cI-40, Fam63a
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75007
Homologene: 32409
Rsrc1
Name: arginine/serine-rich coiled-coil 1
Synonyms: SRrp53, 1200013F24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66880
Homologene: 41147
Tiprl
Name: TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
Synonyms: 1810011K17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226591
Homologene: 7140
Slain1
Name: SLAIN motif family, member 1
Synonyms: 9630044O09Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105439
Homologene: 16943
Znrf3
Name: zinc and ring finger 3
Synonyms: LOC382477
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 407821
Homologene: 46592
Rerg
Name: RAS-like, estrogen-regulated, growth-inhibitor
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232441
Homologene: 50026
Gpr155
Name: G protein-coupled receptor 155
Synonyms: F730029F15Rik, DEPDC3, PGR22, 1110017O10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68526
Homologene: 16584
Acr
Name: acrosin prepropeptide
Synonyms: preproacrosin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 11434
VEGA: 15
HGNC: HGNC:126
Homologene: 855
Nutm2
Name: NUT family member 2
Synonyms: LOC328250, Gm806
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 328250
Homologene: 128615
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: CD169, Siglec-1, Sn
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20612
Homologene: 124458
Kmt5b
Name: lysine methyltransferase 5B
Synonyms: C630029K18Rik, Suv4-20h1, Suv420h1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225888
Homologene: 32351
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: Gm980, LOC381311, A230079K17Rik, Dnahc14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Plekhg4
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Synonyms: 4931414L13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102075
Homologene: 18516
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329628
Homologene: 14377
Fbn2
Name: fibrillin 2
Synonyms: Fib-2, Sne, sy
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Col9a3
Name: collagen, type IX, alpha 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12841
HGNC: HGNC:2219
Homologene: 20438
Astn1
Name: astrotactin 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Cass4
Name: Cas scaffolding protein family member 4
Synonyms: F730031O20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320664
Homologene: 75128
Tdrd7
Name: tudor domain containing 7
Synonyms: 5730495N10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100121
Homologene: 8618
Ahnak
Name: AHNAK nucleoprotein
Synonyms: 2310047C17Rik, DY6, 1110004P15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
L3mbtl1
Name: L3MBTL1 histone methyl-lysine binding protein
Synonyms: L3MBTL1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241764
Homologene: 41846
Rp1l1
Name: retinitis pigmentosa 1 homolog like 1
Synonyms: Rp1hl1, Dcdc4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 271209
VEGA: 14
Homologene: 105870
Or1e1c
Name: olfactory receptor family 1 subfamily E member 1C
Synonyms: Olfr376, GA_x6K02T2P1NL-3535075-3536028, MOR135-12
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258924
Homologene: 133579
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50720
1700006A11Rik
Name: RIKEN cDNA 1700006A11 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71824
Cfap52
Name: cilia and flagella associated protein 52
Synonyms: 4933417B11Rik, Wdr16, 1700019F09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71860
Homologene: 12416
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: flamingo, Adgrc3, Fmi1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Twnk
Name: twinkle mtDNA helicase
Synonyms: twinkle, Twinl, D19Ertd626e, Peo1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226153
VEGA: 19
HGNC: HGNC:1160
Homologene: 11052
Psg20
Name: pregnancy-specific beta-1-glycoprotein 20
Synonyms: cea7, EG434540
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434540
Homologene: 110989
Aox4
Name: aldehyde oxidase 4
Synonyms: 2310003G12Rik, AOH2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71872
Homologene: 70273
Zfp955a
Name: zinc finger protein 955A
Synonyms: AI842447
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77652
VEGA: 17
Homologene: 104925
Ppfia3
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
Synonyms: 2410127E16Rik, Liprin-alpha3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76787
HGNC: HGNC:9247
Homologene: 37833
Adam6b
Name: a disintegrin and metallopeptidase domain 6B
Synonyms: 4930523C11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238405
Homologene: 128362
Hscb
Name: HscB iron-sulfur cluster co-chaperone
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100900
Homologene: 13945
Vmn2r16
Name: vomeronasal 2, receptor 16
Synonyms: EG384220
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384220
Homologene: 104825
Slc9a9
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 9
Synonyms: 5730527A11Rik, Nhe9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 331004
Homologene: 69753
Setd7
Name: SET domain containing (lysine methyltransferase) 7
Synonyms: 1600028F23Rik, Set7, KMT7, Set7/9
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 73251
Homologene: 12741
Recql
Name: RecQ protein-like
Synonyms: RecQ1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19691
HGNC: HGNC:9948
Homologene: 56279
Itgb5
Name: integrin beta 5
Synonyms: [b]5B, beta-5, [b]5A, beta5, [b]5, ESTM23, [b]-5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16419
HGNC: HGNC:6160
Homologene: 20511
Or52ae7
Name: olfactory receptor family 52 subfamily AE member 7
Synonyms: Olfr608, MOR26-3, GA_x6K02T2PBJ9-6191595-6192545
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258751
Tpp1
Name: tripeptidyl peptidase I
Synonyms: Cln2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12751
HGNC: HGNC:2073
Homologene: 335
Mos
Name: Moloney sarcoma oncogene
Synonyms: c-mos
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17451
HGNC: HGNC:7199
Homologene: 3919
Gm8369
Name: predicted gene 8369
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 666926
Zfp810
Name: zinc finger protein 810
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235050
VEGA: 9
Homologene: 138299
Mmel1
Name: membrane metallo-endopeptidase-like 1
Synonyms: SEP, NEPLP alpha, NEPLP beta, Nl1, NEPLP gamma, Mell1, Nep2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 27390
Homologene: 22778
C1qbp
Name: complement component 1, q subcomponent binding protein
Synonyms: P32, HABP1, D11Wsu182e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12261
HGNC: HGNC:1243
Homologene: 31023
Glrx2
Name: glutaredoxin 2
Synonyms: Grx2, 1700010P22Rik, thioltransferase
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 69367
Homologene: 41098
Slc25a10
Name: solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
Synonyms: Dic
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 27376
Homologene: 6519
Tmem185b
Name: transmembrane protein 185B
Synonyms: 2500001K11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226351
Homologene: 15760
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 58,239,303 bp (GRCm38)
  • G to C, chromosome 1 at 119,527,018 bp (GRCm38)
  • A to G, chromosome 1 at 143,746,554 bp (GRCm38)
  • A to C, chromosome 1 at 153,545,284 bp (GRCm38)
  • A to G, chromosome 1 at 158,664,049 bp (GRCm38)
  • A to G, chromosome 1 at 165,222,578 bp (GRCm38)
  • A to G, chromosome 1 at 181,598,944 bp (GRCm38)
  • A to G, chromosome 2 at 73,362,436 bp (GRCm38)
  • T to A, chromosome 2 at 131,079,316 bp (GRCm38)
  • A to T, chromosome 2 at 162,970,308 bp (GRCm38)
  • C to T, chromosome 2 at 172,426,736 bp (GRCm38)
  • G to A, chromosome 2 at 180,606,529 bp (GRCm38)
  • A to G, chromosome 3 at 38,889,183 bp (GRCm38)
  • A to T, chromosome 3 at 51,542,690 bp (GRCm38)
  • T to A, chromosome 3 at 67,349,995 bp (GRCm38)
  • A to T, chromosome 3 at 95,294,865 bp (GRCm38)
  • C to T, chromosome 3 at 124,406,446 bp (GRCm38)
  • T to C, chromosome 4 at 3,871,186 bp (GRCm38)
  • T to A, chromosome 4 at 46,025,946 bp (GRCm38)
  • A to T, chromosome 4 at 154,892,828 bp (GRCm38)
  • T to A, chromosome 5 at 109,363,811 bp (GRCm38)
  • T to C, chromosome 5 at 110,836,015 bp (GRCm38)
  • T to C, chromosome 5 at 137,464,514 bp (GRCm38)
  • A to G, chromosome 6 at 137,056,254 bp (GRCm38)
  • C to T, chromosome 6 at 142,359,920 bp (GRCm38)
  • T to A, chromosome 7 at 18,682,583 bp (GRCm38)
  • T to A, chromosome 7 at 45,356,575 bp (GRCm38)
  • A to G, chromosome 7 at 103,469,950 bp (GRCm38)
  • A to G, chromosome 7 at 105,748,897 bp (GRCm38)
  • T to C, chromosome 8 at 105,376,291 bp (GRCm38)
  • C to T, chromosome 8 at 122,890,943 bp (GRCm38)
  • T to C, chromosome 9 at 22,278,503 bp (GRCm38)
  • A to T, chromosome 9 at 22,372,240 bp (GRCm38)
  • T to G, chromosome 9 at 94,670,182 bp (GRCm38)
  • T to A, chromosome 9 at 108,827,323 bp (GRCm38)
  • AAGA to AAGAGA, chromosome 10 at 21,992,391 bp (GRCm38)
  • T to A, chromosome 10 at 108,260,886 bp (GRCm38)
  • T to C, chromosome 11 at 5,444,465 bp (GRCm38)
  • A to T, chromosome 11 at 49,689,337 bp (GRCm38)
  • T to A, chromosome 11 at 67,931,813 bp (GRCm38)
  • G to A, chromosome 11 at 70,982,923 bp (GRCm38)
  • G to A, chromosome 11 at 73,374,985 bp (GRCm38)
  • A to C, chromosome 11 at 94,097,742 bp (GRCm38)
  • G to A, chromosome 11 at 98,996,857 bp (GRCm38)
  • A to G, chromosome 11 at 120,495,486 bp (GRCm38)
  • G to T, chromosome 12 at 113,490,556 bp (GRCm38)
  • T to C, chromosome 13 at 12,434,259 bp (GRCm38)
  • C to A, chromosome 13 at 50,474,981 bp (GRCm38)
  • T to A, chromosome 14 at 61,213,432 bp (GRCm38)
  • A to G, chromosome 14 at 64,031,677 bp (GRCm38)
  • A to T, chromosome 14 at 103,688,185 bp (GRCm38)
  • C to T, chromosome 15 at 37,978,027 bp (GRCm38)
  • T to A, chromosome 15 at 89,573,237 bp (GRCm38)
  • T to A, chromosome 16 at 33,919,965 bp (GRCm38)
  • A to G, chromosome 17 at 33,242,613 bp (GRCm38)
  • T to C, chromosome 17 at 46,812,018 bp (GRCm38)
  • C to T, chromosome 18 at 58,053,027 bp (GRCm38)
  • T to A, chromosome 19 at 3,815,587 bp (GRCm38)
  • T to C, chromosome 19 at 9,007,355 bp (GRCm38)
  • T to C, chromosome 19 at 11,511,733 bp (GRCm38)
  • T to A, chromosome 19 at 45,010,183 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9683 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069476-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.