Strain Name:
C57BL/6J-MtgxR9736Btlr/Mmmh
Stock Number:
069982-MU
Citation ID:
RRID:MMRRC_069982-MU
Other Names:
R9736 (G1)
Major Collection:

Strain Information

Grin3a
Name: glutamate receptor ionotropic, NMDA3A
Synonyms: NR3A, NMDAR-L, A830097C19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242443
Homologene: 128613
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Wwp1
Name: WW domain containing E3 ubiquitin protein ligase 1
Synonyms: Tiul1, 8030445B08Rik, AIP5, SDRP1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 107568
Homologene: 21385
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103554
Homologene: 113742
Micu1
Name: mitochondrial calcium uptake 1
Synonyms: Cbara1, C730016L05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216001
HGNC: HGNC:1530
Homologene: 4431
Ctnnd1
Name: catenin delta 1
Synonyms: Catns, Ctnnd, catenin (cadherin associated protein), delta 1, p120-catenin, P120
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12388
HGNC: HGNC:2515
Homologene: 1017
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: 8030453L17Rik, KMT2H, chromatin remodeling factor, E430018P19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Wdr37
Name: WD repeat domain 37
Synonyms: 3110035P10Rik, 4933417A01Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 207615
Homologene: 40914
Crygb
Name: crystallin, gamma B
Synonyms: DGcry-3, Cryg-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12965
HGNC: HGNC:2409
Homologene: 3816
Ptprm
Name: protein tyrosine phosphatase receptor type M
Synonyms: RPTPmu
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19274
VEGA: 17
HGNC: HGNC:9675
Homologene: 37694
Lmo7
Name: LIM domain only 7
Synonyms: LOC380928, FBXO20
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Cntfr
Name: ciliary neurotrophic factor receptor
Synonyms: Cntfralpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12804
HGNC: HGNC:2170
Homologene: 9619
Apc
Name: APC, WNT signaling pathway regulator
Synonyms: adenomatosis polyposis coli, Min, CC1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 11789
HGNC: HGNC:583
Homologene: 30950
Qser1
Name: glutamine and serine rich 1
Synonyms: 4732486I23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99003
Homologene: 11710
Atp10a
Name: ATPase, class V, type 10A
Synonyms: pfatp, Atp10c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11982
Homologene: 56461
Fat2
Name: FAT atypical cadherin 2
Synonyms: EMI2, mKIAA0811, LOC245827, Fath2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Fhod1
Name: formin homology 2 domain containing 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234686
Homologene: 136406
Mab21l4
Name: mab-21-like 4
Synonyms: 2310007B03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71874
Homologene: 11761
Gucy2d
Name: guanylate cyclase 2d
Synonyms: guanylyl cyclase D
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14918
Homologene: 71540
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: Myhs-f, MyHC-IIa, MHC2A, Myhsf1, Myhs-f1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
Cdhr2
Name: cadherin-related family member 2
Synonyms: Pcdh24, LOC268663
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 268663
Homologene: 134510
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235505
Homologene: 25183
Irs2
Name: insulin receptor substrate 2
Synonyms: Irs-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 384783
HGNC: HGNC:6126
Homologene: 2778
Dpp10
Name: dipeptidylpeptidase 10
Synonyms: DPRP3, 6430601K09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269109
Homologene: 41400
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: 3110047P20Rik, B830017A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319807
Homologene: 14974
Gsdma
Name: gasdermin A
Synonyms: H312E, Gsdm1, Gsdm, Gsdma1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 57911
Homologene: 10962
Zbbx
Name: zinc finger, B-box domain containing
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213234
Homologene: 11661
Pon3
Name: paraoxonase 3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 269823
HGNC: HGNC:9206
Homologene: 37371
Gopc
Name: golgi associated PDZ and coiled-coil motif containing
Synonyms: 2210402P09Rik, GOPC1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 94221
VEGA: 10
Homologene: 10695
D6Ertd527e
Name: DNA segment, Chr 6, ERATO Doi 527, expressed
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 52372
Or5an1c
Name: olfactory receptor family 5 subfamily AN member 1C
Synonyms: MOR214-9, Olfr262, GA_x6K02T2N4A9-18144-19082, MOR214-1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258683
Calhm2
Name: calcium homeostasis modulator family member 2
Synonyms: 2810048G17Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72691
Homologene: 9303
Cpox
Name: coproporphyrinogen oxidase
Synonyms: Cpo, M100835, clone 560, cac, nct
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12892
VEGA: 16
HGNC: HGNC:2321
Homologene: 76
Or4k45
Name: olfactory receptor family 4 subfamily K member 45
Synonyms: MOR248-10, GA_x6K02T2Q125-72616944-72616006, Olfr1295
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258398
Homologene: 74058
Cage1
Name: cancer antigen 1
Synonyms: Ctag3, 4933427I01Rik, CAGE1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71213
Homologene: 18484
Adgrf2
Name: adhesion G protein-coupled receptor F2
Synonyms: Gpr111, PGR20
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 435529
Homologene: 45213
Or5al5
Name: olfactory receptor family 5 subfamily AL member 5
Synonyms: Olfr1517, MOR185-9P, MOR185-5, MOR185-5, MOR185-5, Olfr1039, GA_x6K02T2Q125-47600809-47599850
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257950
Homologene: 79382
Dmgdh
Name: dimethylglycine dehydrogenase precursor
Synonyms: 1200014D15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 74129
Homologene: 8372
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 65,080,548 bp (GRCm38)
  • A to G, chromosome 1 at 93,159,939 bp (GRCm38)
  • T to A, chromosome 1 at 123,334,359 bp (GRCm38)
  • T to C, chromosome 2 at 84,612,086 bp (GRCm38)
  • T to A, chromosome 2 at 86,131,296 bp (GRCm38)
  • A to G, chromosome 2 at 104,789,643 bp (GRCm38)
  • A to T, chromosome 2 at 111,565,281 bp (GRCm38)
  • A to G, chromosome 3 at 75,061,434 bp (GRCm38)
  • A to G, chromosome 3 at 88,984,426 bp (GRCm38)
  • T to A, chromosome 4 at 19,631,202 bp (GRCm38)
  • T to C, chromosome 4 at 41,658,290 bp (GRCm38)
  • C to A, chromosome 4 at 49,672,472 bp (GRCm38)
  • A to G, chromosome 5 at 63,794,257 bp (GRCm38)
  • A to G, chromosome 6 at 5,232,339 bp (GRCm38)
  • G to C, chromosome 6 at 87,111,857 bp (GRCm38)
  • T to A, chromosome 7 at 58,824,330 bp (GRCm38)
  • G to A, chromosome 7 at 98,443,476 bp (GRCm38)
  • G to A, chromosome 8 at 11,008,217 bp (GRCm38)
  • G to A, chromosome 8 at 105,332,965 bp (GRCm38)
  • C to T, chromosome 9 at 78,712,636 bp (GRCm38)
  • A to T, chromosome 10 at 52,353,462 bp (GRCm38)
  • C to T, chromosome 10 at 59,863,301 bp (GRCm38)
  • T to A, chromosome 11 at 30,847,411 bp (GRCm38)
  • T to A, chromosome 11 at 55,303,925 bp (GRCm38)
  • T to C, chromosome 11 at 67,173,173 bp (GRCm38)
  • C to T, chromosome 11 at 98,676,343 bp (GRCm38)
  • C to A, chromosome 13 at 8,861,100 bp (GRCm38)
  • A to C, chromosome 13 at 38,023,417 bp (GRCm38)
  • T to C, chromosome 13 at 54,724,228 bp (GRCm38)
  • T to G, chromosome 13 at 93,706,650 bp (GRCm38)
  • A to G, chromosome 14 at 101,920,493 bp (GRCm38)
  • A to G, chromosome 14 at 103,197,416 bp (GRCm38)
  • A to G, chromosome 16 at 58,674,383 bp (GRCm38)
  • A to G, chromosome 17 at 42,711,321 bp (GRCm38)
  • T to A, chromosome 17 at 66,690,567 bp (GRCm38)
  • T to A, chromosome 18 at 34,317,770 bp (GRCm38)
  • A to T, chromosome 19 at 12,241,556 bp (GRCm38)
  • G to A, chromosome 19 at 47,133,158 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9736 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069982-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.