Strain Name:
C57BL/6J-MtgxR9751Btlr/Mmmh
Stock Number:
069997-MU
Citation ID:
RRID:MMRRC_069997-MU
Other Names:
R9751 (G1)
Major Collection:

Strain Information

Tyrp1
Name: tyrosinase-related protein 1
Synonyms: TRP1, TRP-1, Oca3, isa, Tyrp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22178
Homologene: 464
Rptor
Name: regulatory associated protein of MTOR, complex 1
Synonyms: Rap, 4932417H02Rik, raptor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74370
Homologene: 80210
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Csf2
Name: colony stimulating factor 2 (granulocyte-macrophage)
Synonyms: Gm-CSf, GMCSF, MGI-IGM, Csfgm
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12981
HGNC: HGNC:2434
Homologene: 600
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: EGF-TM7, Ly71, F4/80, Emr1, TM7LN3, DD7A5-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Egf
Name: epidermal growth factor
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13645
HGNC: HGNC:3229
Homologene: 1483
Rtn4rl2
Name: reticulon 4 receptor-like 2
Synonyms: Ngrh1, Ngr2, Ngrl3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269295
Homologene: 18683
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224273
Homologene: 28544
Ube2g2
Name: ubiquitin-conjugating enzyme E2G 2
Synonyms: D10Xrf369, Ubc7p, 1110003O05Rik, UBC7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22213
Homologene: 6599
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: GMAP-210, TRIP230, 3110031G15Rik, 6030460N08Rik, 2610511G22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 109181
Homologene: 20897
Brwd1
Name: bromodomain and WD repeat domain containing 1
Synonyms: Wdr9, D530019K20Rik, G1-403-16, 5330419I02Rik, repro5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 93871
Homologene: 23130
Nap1l4
Name: nucleosome assembly protein 1-like 4
Synonyms: D7Wsu30e, Nap2, 2810410H14Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17955
HGNC: HGNC:7640
Homologene: 133933
Bltp1
Name: bridge-like lipid transfer protein family member 1
Synonyms: Tweek, FSA, 4932438A13Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229227
Homologene: 52105
Tbc1d5
Name: TBC1 domain family, member 5
Synonyms: 1600014N05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72238
VEGA: 17
Homologene: 8834
Dpp8
Name: dipeptidylpeptidase 8
Synonyms: 4932434F09Rik, 2310004I03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74388
VEGA: 9
Homologene: 57098
Med13
Name: mediator complex subunit 13
Synonyms: 1110067M05Rik, Trap240, Thrap1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327987
Homologene: 21067
Paxbp1
Name: PAX3 and PAX7 binding protein 1
Synonyms: Pax3/7bp, 1810007M14Rik, Gcfc1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67367
Homologene: 9604
Csnk1g2
Name: casein kinase 1, gamma 2
Synonyms: 2810429I12Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103236
VEGA: 10
HGNC: HGNC:2455
Homologene: 100845
Ncapg
Name: non-SMC condensin I complex, subunit G
Synonyms: 5730507H05Rik, Hcapg, MFT.M05.13
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54392
Homologene: 44071
Cachd1
Name: cache domain containing 1
Synonyms: Vwcd1, 1190007F10Rik, B430218L07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320508
Homologene: 10854
Dync2i1
Name: dynein 2 intermediate chain 1
Synonyms: Wdr60, D430033N04Rik, Dync2l1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217935
VEGA: 12
Homologene: 23067
Igflr1
Name: IGF-like family receptor 1
Synonyms: F630003I17Rik, Tmem149
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101883
Homologene: 49779
Myof
Name: myoferlin
Synonyms: Fer1l3, E030042N20Rik, 2310051D19Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Bmper
Name: BMP-binding endothelial regulator
Synonyms: 3110056H04Rik, Cv2, CV-2, crossveinless-2, Crim3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73230
VEGA: 9
Homologene: 12494
Fam20a
Name: FAM20A, golgi associated secretory pathway pseudokinase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 208659
Homologene: 9719
Abca4
Name: ATP-binding cassette, sub-family A member 4
Synonyms: Rim protein, RmP, D430003I15Rik, Abc10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Slc35f4
Name: solute carrier family 35, member F4
Synonyms: 4930550L21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75288
Homologene: 45939
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: LOC381311, Gm980, A230079K17Rik, Dnahc14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Pip4p1
Name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
Synonyms: Tmem55b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219024
Homologene: 10279
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Gm11639
Name: predicted gene 11639
Synonyms: Gm11639, Efcab15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 105242472
Ankrd7
Name: ankyrin repeat domain 7
Synonyms: 4930532L20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 75196
Homologene: 35506
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235505
Homologene: 25183
Plce1
Name: phospholipase C, epsilon 1
Synonyms: PLCepsilon, 4933403A21Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 74055
Homologene: 9478
Hycc1
Name: hyccin PI4KA lipid kinase complex subunit 1
Synonyms: hyccin, Fam126a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 84652
Homologene: 57175
Or5d40
Name: olfactory receptor family 5 subfamily D member 40
Synonyms: Olfr1168, GA_x6K02T2Q125-49669483-49670421, MOR174-13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258524
Homologene: 128091
Or4c119
Name: olfactory receptor family 4 subfamily C member 119
Synonyms: Olfr1224, GA_x6K02T2Q125-50635980-50635046, MOR233-15
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258026
Trim65
Name: tripartite motif-containing 65
Synonyms: 4732463G12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 338364
Homologene: 27844
Map3k6
Name: mitogen-activated protein kinase kinase kinase 6
Synonyms: Ask2, MEKK6, MAPKKK6
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 53608
HGNC: HGNC:6858
Homologene: 3435
Styk1
Name: serine/threonine/tyrosine kinase 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243659
Homologene: 49545
Or5p68
Name: olfactory receptor family 5 subfamily P member 68
Synonyms: MOR204-35, Olfr493, GA_x6K02T2PBJ9-10676998-10676054
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258307
Homologene: 17188
Meioc
Name: meiosis specific with coiled-coil domain
Synonyms: LOC380729, LOC268491, Gm1564
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268491
Homologene: 19559
Tas2r115
Name: taste receptor, type 2, member 115
Synonyms: Tas2r15, T2R15, mGR15, mt2r49
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 353325
Or4c10b
Name: olfactory receptor family 4 subfamily C member 10B
Synonyms: GA_x6K02T2Q125-51319458-51320387, Olfr1257, MOR232-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258984
Homologene: 115501
C1s2
Name: complement component 1, s subcomponent 2
Synonyms: Gm5077
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 317677
HGNC: HGNC:1247
Homologene: 1314
Mcpt4
Name: mast cell protease 4
Synonyms: Mcp-4, MMCP-4B, MMCP-4A, MMCP-4, myonase, Mcp4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17227
VEGA: 14
Homologene: 130645
Krt79
Name: keratin 79
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223917
Homologene: 89169
Clstn2
Name: calsyntenin 2
Synonyms: Cst-2, CSTN2, CS2, 2900042C18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 64085
Homologene: 49698
Dlg2
Name: discs large MAGUK scaffold protein 2
Synonyms: Gm21505, A330103J02Rik, PSD93, Chapsyn-110, B330007M19Rik, B230218P12Rik, Dlgh2, LOC382816
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23859
HGNC: HGNC:2901
Homologene: 1046
Cacng4
Name: calcium channel, voltage-dependent, gamma subunit 4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54377
HGNC: HGNC:1408
Homologene: 8674
Or5d39
Name: olfactory receptor family 5 subfamily D member 39
Synonyms: MOR174-16, Olfr1167, GA_x6K02T2Q125-49641892-49640942
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258291
Homologene: 138307
Eif1ad19
Name: eukaryotic translation initiation factor 1A domain containing 19
Synonyms: Gm21319
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 100861908
Homologene: 103865
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 181,792,045 bp (GRCm38)
  • T to C, chromosome 2 at 82,987,897 bp (GRCm38)
  • T to G, chromosome 2 at 84,880,695 bp (GRCm38)
  • T to A, chromosome 2 at 88,149,270 bp (GRCm38)
  • T to A, chromosome 2 at 88,184,916 bp (GRCm38)
  • C to T, chromosome 2 at 89,156,438 bp (GRCm38)
  • C to T, chromosome 2 at 89,881,612 bp (GRCm38)
  • A to G, chromosome 3 at 37,011,740 bp (GRCm38)
  • A to G, chromosome 3 at 122,087,477 bp (GRCm38)
  • C to A, chromosome 3 at 129,754,889 bp (GRCm38)
  • A to G, chromosome 4 at 80,840,775 bp (GRCm38)
  • G to A, chromosome 4 at 100,966,241 bp (GRCm38)
  • A to G, chromosome 4 at 133,251,857 bp (GRCm38)
  • C to T, chromosome 5 at 23,991,750 bp (GRCm38)
  • T to C, chromosome 5 at 45,693,853 bp (GRCm38)
  • G to A, chromosome 6 at 18,868,025 bp (GRCm38)
  • T to C, chromosome 6 at 84,186,468 bp (GRCm38)
  • G to T, chromosome 6 at 124,625,594 bp (GRCm38)
  • CTCTTCATGATTTTCTT to CTCTT, chromosome 6 at 131,301,649 bp (GRCm38)
  • A to G, chromosome 6 at 132,737,955 bp (GRCm38)
  • A to T, chromosome 7 at 30,567,228 bp (GRCm38)
  • C to A, chromosome 7 at 90,915,523 bp (GRCm38)
  • T to C, chromosome 7 at 108,346,438 bp (GRCm38)
  • A to C, chromosome 7 at 143,534,395 bp (GRCm38)
  • C to T, chromosome 9 at 23,406,713 bp (GRCm38)
  • C to T, chromosome 9 at 65,053,171 bp (GRCm38)
  • C to A, chromosome 9 at 78,698,160 bp (GRCm38)
  • A to T, chromosome 9 at 89,089,517 bp (GRCm38)
  • A to G, chromosome 9 at 97,457,650 bp (GRCm38)
  • G to A, chromosome 10 at 77,644,473 bp (GRCm38)
  • T to A, chromosome 10 at 80,637,911 bp (GRCm38)
  • A to T, chromosome 11 at 54,249,594 bp (GRCm38)
  • T to C, chromosome 11 at 86,299,158 bp (GRCm38)
  • T to A, chromosome 11 at 102,675,593 bp (GRCm38)
  • G to A, chromosome 11 at 104,893,085 bp (GRCm38)
  • A to G, chromosome 11 at 107,735,193 bp (GRCm38)
  • T to A, chromosome 11 at 109,675,166 bp (GRCm38)
  • C to A, chromosome 11 at 116,130,738 bp (GRCm38)
  • A to G, chromosome 11 at 119,887,138 bp (GRCm38)
  • T to C, chromosome 12 at 87,773,756 bp (GRCm38)
  • C to T, chromosome 12 at 101,884,506 bp (GRCm38)
  • T to A, chromosome 12 at 116,241,783 bp (GRCm38)
  • A to G, chromosome 14 at 49,298,834 bp (GRCm38)
  • A to G, chromosome 14 at 50,927,979 bp (GRCm38)
  • A to G, chromosome 14 at 56,060,054 bp (GRCm38)
  • T to G, chromosome 15 at 101,930,761 bp (GRCm38)
  • A to T, chromosome 16 at 59,557,524 bp (GRCm38)
  • A to G, chromosome 16 at 91,027,300 bp (GRCm38)
  • A to T, chromosome 16 at 95,993,815 bp (GRCm38)
  • A to G, chromosome 17 at 50,874,652 bp (GRCm38)
  • G to A, chromosome 17 at 57,450,101 bp (GRCm38)
  • T to C, chromosome 19 at 37,936,370 bp (GRCm38)
  • C to T, chromosome 19 at 38,728,970 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9751 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069997-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.