Strain Name:
C57BL/6J-MtgxR9799Btlr/Mmmh
Stock Number:
070044-MU
Citation ID:
RRID:MMRRC_070044-MU
Other Names:
R9799 (G1)
Major Collection:

Strain Information

Utrn
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Emx2
Name: empty spiracles homeobox 2
Synonyms: Pdo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13797
HGNC: HGNC:3341
Homologene: 3023
Gcm2
Name: glial cells missing homolog 2
Synonyms: Gcm1-rs2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107889
VEGA: 13
HGNC: HGNC:4198
Homologene: 3490
Arid4b
Name: AT-rich interaction domain 4B
Synonyms: Rbp1l1, 6330417L24Rik, RBBP1L1, 6720480E17Rik, SAP180, BRCAA1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 94246
Homologene: 12847
Tiparp
Name: TCDD-inducible poly(ADP-ribose) polymerase
Synonyms: DDF1, PARP-7, PARP7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99929
Homologene: 9167
Arhgef10
Name: Rho guanine nucleotide exchange factor 10
Synonyms: 6430549H08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234094
Homologene: 22827
Gnai2
Name: G protein subunit alpha i2
Synonyms: Gnai-2, Galphai2, Gia
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14678
HGNC: HGNC:4385
Homologene: 55539
Top1
Name: topoisomerase (DNA) I
Synonyms: D130064I21Rik, Top-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21969
Homologene: 2467
Ppp1r14b
Name: protein phosphatase 1, regulatory inhibitor subunit 14B
Synonyms: Png, PLCB3N, PHI-1, AOM172
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18938
VEGA: 19
HGNC: HGNC:9057
Homologene: 7483
Ddx50
Name: DExD box helicase 50
Synonyms: 4933429B04Rik, 8430408E17Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 50, RH-II/Gubeta, GU2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 94213
VEGA: 10
Homologene: 56986
Sema3f
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
Synonyms: Semak, Sema IV
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20350
Homologene: 20885
Psmd1
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
Synonyms: P112, S1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70247
HGNC: HGNC:9554
Homologene: 2100
Erbin
Name: Erbb2 interacting protein
Synonyms: 1700028E05Rik, Erbb2ip, Erbin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 59079
Homologene: 41282
Msh2
Name: mutS homolog 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17685
HGNC: HGNC:7325
Homologene: 210
Wwc2
Name: WW, C2 and coiled-coil domain containing 2
Synonyms: D8Ertd594e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52357
Homologene: 32618
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Pemt
Name: phosphatidylethanolamine N-methyltransferase
Synonyms: Pempt, Pempt2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18618
HGNC: HGNC:8830
Homologene: 6291
Lpin1
Name: lipin 1
Synonyms: Lipin1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14245
VEGA: 12
Homologene: 9266
Lrrtm3
Name: leucine rich repeat transmembrane neuronal 3
Synonyms: 9630044H04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216028
Homologene: 37110
Sugp1
Name: SURP and G patch domain containing 1
Synonyms: Sf4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70616
Homologene: 12360
Ndfip2
Name: Nedd4 family interacting protein 2
Synonyms: 0710001O20Rik, 9130207N19Rik, N4wbp5a
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 76273
Homologene: 12636
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Cyp2r1
Name: cytochrome P450, family 2, subfamily r, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244209
Homologene: 75210
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: CD169, Siglec-1, Sn
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20612
Homologene: 124458
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 667663
HGNC: HGNC:7601
Homologene: 49486
Rb1cc1
Name: RB1-inducible coiled-coil 1
Synonyms: Fip200, 2900055E04Rik, 5930404L04Rik, Cc1, LaXp180
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12421
Homologene: 7659
Pabpc6
Name: poly(A) binding protein, cytoplasmic 6
Synonyms: 4932702K14Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67543
VEGA: 17
Homologene: 129776
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Arhgef38
Name: Rho guanine nucleotide exchange factor 38
Synonyms: D630013G24Rik, 9130221D24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77669
Homologene: 137396
Cimap1a
Name: ciliary microtubule associated protein 1A
Synonyms: Odf3, 1700011O04Rik, SHIPPO1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69287
Homologene: 12306
Xab2
Name: XPA binding protein 2
Synonyms: 0610041O14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67439
Homologene: 5738
Rxfp1
Name: relaxin/insulin-like family peptide receptor 1
Synonyms: LOC381489, Lgr7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 381489
Homologene: 11007
Kdr
Name: kinase insert domain protein receptor
Synonyms: VEGF receptor-2, VEGFR-2, VEGFR2, orv, vascular endothelial growth factor receptor- 2, Flk-1, Flk1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16542
HGNC: HGNC:6307
Homologene: 55639
Nfatc2ip
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
Synonyms: NIP45, D7Ertd304e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18020
Homologene: 7862
Meiob
Name: meiosis specific with OB domains
Synonyms: 4930528F23Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 75178
VEGA: 17
Homologene: 102013
Gstp2
Name: glutathione S-transferase, pi 2
Synonyms: Gst p-2, GSTpiA, Gst3, Gst-3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14869
HGNC: HGNC:4638
Homologene: 660
Tmem217
Name: transmembrane protein 217
Synonyms: EG622644, 4933413N12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71138
VEGA: 17
Homologene: 51671
Pde3b
Name: phosphodiesterase 3B, cGMP-inhibited
Synonyms: 9830102A01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18576
HGNC: HGNC:8779
Homologene: 709
Tubb2a
Name: tubulin, beta 2A class IIA
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 22151
VEGA: 13
Homologene: 134314
Or8k41
Name: olfactory receptor family 8 subfamily K member 41
Synonyms: Olfr1071, GA_x6K02T2Q125-47962802-47962551, MOR189-3, Olfr228, GA_x6K02T0101M-139-669
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258400
Homologene: 17233
Rimbp3
Name: RIMS binding protein 3
Synonyms: LOC385766, LOC239731, RIM-BP3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239731
Homologene: 77940
Akr1b8
Name: aldo-keto reductase family 1, member B8
Synonyms: Fgrp, Fgfrp
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14187
Homologene: 116462
Serpinb3a
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
Synonyms: Sqn5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20248
Homologene: 76659
Plch1
Name: phospholipase C, eta 1
Synonyms: Plcl3, PLCeta1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269437
Homologene: 88833
Cr2
Name: complement receptor 2
Synonyms: CD35, Cr-2, Cr1, C3DR, CD21, Cr-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Ccdc136
Name: coiled-coil domain containing 136
Synonyms: 4921511K06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232664
Homologene: 23378
Ccl25
Name: C-C motif chemokine ligand 25
Synonyms: CKb15, Scya25, TECK
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20300
Homologene: 4109
Csnka2ip
Name: casein kinase 2, alpha prime interacting protein
Synonyms: Ckt2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224291
Homologene: 77570
Or52e19
Name: olfactory receptor family 52 subfamily E member 19
Synonyms: ENSMUSG00000073953, Olfr596-ps1, Gm15117, GA_x6K02T2PBJ9-6019769-6019943, Olfr596
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100041187
Homologene: 121535
Mterf3
Name: mitochondrial transcription termination factor 3
Synonyms: 2410017I18Rik, Mterfd1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66410
Homologene: 9310
Vtn
Name: vitronectin
Synonyms: Vn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22370
Homologene: 532
Rab3gap1
Name: RAB3 GTPase activating protein subunit 1
Synonyms: p130, 1700003B17Rik, 4732493F09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226407
Homologene: 45617
Srd5a2
Name: steroid 5 alpha-reductase 2
Synonyms: 5ART2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 94224
VEGA: 17
Homologene: 37292
Agxt
Name: alanine-glyoxylate aminotransferase
Synonyms: Agt1, Agxt1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11611
HGNC: HGNC:341
Homologene: 37251
Gpr150
Name: G protein-coupled receptor 150
Synonyms: C030001A19Rik, PGR11
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238725
Homologene: 18457
Pnma2
Name: paraneoplastic antigen MA2
Synonyms: A830049P17Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239157
HGNC: HGNC:9159
Homologene: 5249
Tbc1d30
Name: TBC1 domain family, member 30
Synonyms: 4930505D03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74694
VEGA: 10
Homologene: 18930
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 6,244,902 bp (GRCm38)
  • T to C, chromosome 1 at 53,518,809 bp (GRCm38)
  • T to A, chromosome 1 at 86,126,514 bp (GRCm38)
  • T to C, chromosome 1 at 93,135,348 bp (GRCm38)
  • T to G, chromosome 1 at 107,047,162 bp (GRCm38)
  • A to G, chromosome 1 at 127,930,752 bp (GRCm38)
  • T to A, chromosome 1 at 195,160,680 bp (GRCm38)
  • C to T, chromosome 2 at 22,600,169 bp (GRCm38)
  • A to T, chromosome 2 at 86,483,388 bp (GRCm38)
  • G to T, chromosome 2 at 131,074,021 bp (GRCm38)
  • T to A, chromosome 2 at 160,721,486 bp (GRCm38)
  • A to G, chromosome 3 at 63,698,170 bp (GRCm38)
  • A to T, chromosome 3 at 65,547,552 bp (GRCm38)
  • A to G, chromosome 3 at 79,670,875 bp (GRCm38)
  • T to C, chromosome 3 at 133,149,630 bp (GRCm38)
  • A to G, chromosome 5 at 75,957,092 bp (GRCm38)
  • T to A, chromosome 6 at 29,417,506 bp (GRCm38)
  • G to A, chromosome 6 at 34,356,343 bp (GRCm38)
  • A to T, chromosome 7 at 103,309,858 bp (GRCm38)
  • A to G, chromosome 7 at 114,523,378 bp (GRCm38)
  • A to G, chromosome 7 at 114,551,972 bp (GRCm38)
  • A to G, chromosome 7 at 120,533,775 bp (GRCm38)
  • A to G, chromosome 7 at 126,390,567 bp (GRCm38)
  • A to T, chromosome 7 at 140,850,793 bp (GRCm38)
  • G to T, chromosome 8 at 3,618,182 bp (GRCm38)
  • T to C, chromosome 8 at 4,327,799 bp (GRCm38)
  • T to C, chromosome 8 at 14,940,268 bp (GRCm38)
  • G to T, chromosome 8 at 47,868,560 bp (GRCm38)
  • A to G, chromosome 8 at 70,070,418 bp (GRCm38)
  • C to T, chromosome 9 at 107,635,181 bp (GRCm38)
  • G to T, chromosome 9 at 107,685,363 bp (GRCm38)
  • T to G, chromosome 10 at 12,709,992 bp (GRCm38)
  • A to T, chromosome 10 at 62,634,033 bp (GRCm38)
  • T to A, chromosome 10 at 64,089,970 bp (GRCm38)
  • T to C, chromosome 10 at 121,306,169 bp (GRCm38)
  • A to G, chromosome 11 at 60,046,348 bp (GRCm38)
  • T to C, chromosome 11 at 78,501,799 bp (GRCm38)
  • A to G, chromosome 12 at 16,562,399 bp (GRCm38)
  • T to C, chromosome 13 at 14,184,382 bp (GRCm38)
  • C to T, chromosome 13 at 34,076,624 bp (GRCm38)
  • T to C, chromosome 13 at 41,105,448 bp (GRCm38)
  • T to C, chromosome 13 at 66,914,716 bp (GRCm38)
  • T to C, chromosome 13 at 68,620,842 bp (GRCm38)
  • T to A, chromosome 13 at 68,657,370 bp (GRCm38)
  • T to C, chromosome 13 at 76,056,517 bp (GRCm38)
  • T to C, chromosome 13 at 103,834,876 bp (GRCm38)
  • T to A, chromosome 14 at 66,916,560 bp (GRCm38)
  • T to C, chromosome 14 at 105,258,965 bp (GRCm38)
  • A to G, chromosome 16 at 17,209,777 bp (GRCm38)
  • T to C, chromosome 16 at 64,478,309 bp (GRCm38)
  • C to T, chromosome 17 at 9,669,185 bp (GRCm38)
  • C to T, chromosome 17 at 24,823,600 bp (GRCm38)
  • A to C, chromosome 17 at 29,526,258 bp (GRCm38)
  • A to C, chromosome 17 at 74,024,540 bp (GRCm38)
  • G to T, chromosome 17 at 87,717,505 bp (GRCm38)
  • A to G, chromosome 19 at 4,041,901 bp (GRCm38)
  • A to G, chromosome 19 at 6,975,457 bp (GRCm38)
  • A to G, chromosome 19 at 59,459,604 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9799 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070044-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.