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Strain Name:
C57BL/6J-MtgxR9799Btlr/Mmmh
Stock Number:
070044-MU
Citation ID:
RRID:MMRRC_070044-MU
Other Names:
R9799 (G1)
Major Collection:

Strain Information

Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Emx2
Name: empty spiracles homeobox 2
Synonyms: Pdo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13797
HGNC: HGNC:3341
Homologene: 3023
Gcm2
Name: glial cells missing homolog 2
Synonyms: Gcm1-rs2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107889
VEGA: 13
HGNC: HGNC:4198
Homologene: 3490
Arid4b
Name: AT-rich interaction domain 4B
Synonyms: RBBP1L1, SAP180, BRCAA1, Rbp1l1, 6720480E17Rik, 6330417L24Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 94246
Homologene: 12847
Tiparp
Name: TCDD-inducible poly(ADP-ribose) polymerase
Synonyms: DDF1, PARP-7, PARP7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99929
Homologene: 9167
Arhgef10
Name: Rho guanine nucleotide exchange factor 10
Synonyms: 6430549H08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234094
Homologene: 22827
Gnai2
Name: G protein subunit alpha i2
Synonyms: Gia, Gnai-2, Galphai2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14678
HGNC: HGNC:4385
Homologene: 55539
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 6,244,902 bp (GRCm38)
  • T to C, chromosome 1 at 53,518,809 bp (GRCm38)
  • T to A, chromosome 1 at 86,126,514 bp (GRCm38)
  • T to C, chromosome 1 at 93,135,348 bp (GRCm38)
  • T to G, chromosome 1 at 107,047,162 bp (GRCm38)
  • A to G, chromosome 1 at 127,930,752 bp (GRCm38)
  • T to A, chromosome 1 at 195,160,680 bp (GRCm38)
  • C to T, chromosome 2 at 22,600,169 bp (GRCm38)
  • A to T, chromosome 2 at 86,483,388 bp (GRCm38)
  • G to T, chromosome 2 at 131,074,021 bp (GRCm38)
  • T to A, chromosome 2 at 160,721,486 bp (GRCm38)
  • A to G, chromosome 3 at 63,698,170 bp (GRCm38)
  • A to T, chromosome 3 at 65,547,552 bp (GRCm38)
  • A to G, chromosome 3 at 79,670,875 bp (GRCm38)
  • T to C, chromosome 3 at 133,149,630 bp (GRCm38)
  • A to G, chromosome 5 at 75,957,092 bp (GRCm38)
  • T to A, chromosome 6 at 29,417,506 bp (GRCm38)
  • G to A, chromosome 6 at 34,356,343 bp (GRCm38)
  • A to T, chromosome 7 at 103,309,858 bp (GRCm38)
  • A to G, chromosome 7 at 114,523,378 bp (GRCm38)
  • A to G, chromosome 7 at 114,551,972 bp (GRCm38)
  • A to G, chromosome 7 at 120,533,775 bp (GRCm38)
  • A to G, chromosome 7 at 126,390,567 bp (GRCm38)
  • A to T, chromosome 7 at 140,850,793 bp (GRCm38)
  • G to T, chromosome 8 at 3,618,182 bp (GRCm38)
  • T to C, chromosome 8 at 4,327,799 bp (GRCm38)
  • T to C, chromosome 8 at 14,940,268 bp (GRCm38)
  • G to T, chromosome 8 at 47,868,560 bp (GRCm38)
  • A to G, chromosome 8 at 70,070,418 bp (GRCm38)
  • C to T, chromosome 9 at 107,635,181 bp (GRCm38)
  • G to T, chromosome 9 at 107,685,363 bp (GRCm38)
  • T to G, chromosome 10 at 12,709,992 bp (GRCm38)
  • A to T, chromosome 10 at 62,634,033 bp (GRCm38)
  • T to A, chromosome 10 at 64,089,970 bp (GRCm38)
  • T to C, chromosome 10 at 121,306,169 bp (GRCm38)
  • A to G, chromosome 11 at 60,046,348 bp (GRCm38)
  • T to C, chromosome 11 at 78,501,799 bp (GRCm38)
  • A to G, chromosome 12 at 16,562,399 bp (GRCm38)
  • T to C, chromosome 13 at 14,184,382 bp (GRCm38)
  • C to T, chromosome 13 at 34,076,624 bp (GRCm38)
  • T to C, chromosome 13 at 41,105,448 bp (GRCm38)
  • T to C, chromosome 13 at 66,914,716 bp (GRCm38)
  • T to C, chromosome 13 at 68,620,842 bp (GRCm38)
  • T to A, chromosome 13 at 68,657,370 bp (GRCm38)
  • T to C, chromosome 13 at 76,056,517 bp (GRCm38)
  • T to C, chromosome 13 at 103,834,876 bp (GRCm38)
  • T to A, chromosome 14 at 66,916,560 bp (GRCm38)
  • T to C, chromosome 14 at 105,258,965 bp (GRCm38)
  • A to G, chromosome 16 at 17,209,777 bp (GRCm38)
  • T to C, chromosome 16 at 64,478,309 bp (GRCm38)
  • C to T, chromosome 17 at 9,669,185 bp (GRCm38)
  • C to T, chromosome 17 at 24,823,600 bp (GRCm38)
  • A to C, chromosome 17 at 29,526,258 bp (GRCm38)
  • A to C, chromosome 17 at 74,024,540 bp (GRCm38)
  • G to T, chromosome 17 at 87,717,505 bp (GRCm38)
  • A to G, chromosome 19 at 4,041,901 bp (GRCm38)
  • A to G, chromosome 19 at 6,975,457 bp (GRCm38)
  • A to G, chromosome 19 at 59,459,604 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9799 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070044-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.