Strain Name:
C57BL/6J-MtgxR1102Btlr/Mmmh
Stock Number:
039175-MU
Citation ID:
RRID:MMRRC_039175-MU
Other Names:
R1102 (G1), C57BL/6J-MtgxR1102Btlr
Major Collection:

Strain Information

Ppp5c
Name: protein phosphatase 5, catalytic subunit
Synonyms: ANP receptor, PP5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19060
HGNC: HGNC:9322
Homologene: 4550
Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: 9930031C03Rik, brain spectrin, elf1, spectrin G, beta fodrin, Spnb2, non-erythrocytic, Spnb-2, elf3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20742
Homologene: 2354
Cd36
Name: CD36 molecule
Synonyms: Scarb3, FAT, fatty acid translocase
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12491
HGNC: HGNC:1663
Homologene: 73871
Trdmt1
Name: tRNA aspartic acid methyltransferase 1
Synonyms: Dnmt2, Rnmt2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13434
HGNC: HGNC:2977
Homologene: 3249
Galnt10
Name: polypeptide N-acetylgalactosaminyltransferase 10
Synonyms: C330012K04Rik, GalNAc-T10, Galnt9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171212
Homologene: 14924
Ndrg1
Name: N-myc downstream regulated gene 1
Synonyms: Ndr1, CMT4D, Ndrl, CAP43, TDD5, DRG1, Tdd5, PROXY1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17988
HGNC: HGNC:7679
Homologene: 55953
Rfx3
Name: regulatory factor X, 3 (influences HLA class II expression)
Synonyms: C230093O12Rik, MRFX3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19726
HGNC: HGNC:9984
Homologene: 7917
Oxtr
Name: oxytocin receptor
Synonyms: OTR
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18430
HGNC: HGNC:8529
Homologene: 20255
Sacm1l
Name: SAC1 suppressor of actin mutations 1-like (yeast)
Synonyms: Sac1p, SAC1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83493
VEGA: 9
Homologene: 6320
Cct2
Name: chaperonin containing TCP1 subunit 2
Synonyms: Cctb
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12461
VEGA: 10
HGNC: HGNC:1615
Homologene: 4696
Pdzd4
Name: PDZ domain containing 4
Synonyms: Kiaa1444-hp, PDZD4, PDZRN4L, Xlu, LU1, Pdzk4, D130075J17Rik, Pdzrnk4l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245469
Homologene: 13046
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: 2610042O15Rik, C86341, Mms19, Mms19l
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72199
Homologene: 41480
Emsy
Name: EMSY, BRCA2-interacting transcriptional repressor
Synonyms: 2210018M11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233545
Homologene: 32465
Cep350
Name: centrosomal protein 350
Synonyms: 4933409L06Rik, 6430546F08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74081
Homologene: 8879
Tmem245
Name: transmembrane protein 245
Synonyms: D730040F13Rik, A630051L19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242474
HGNC: HGNC:1363
Homologene: 41841
Ccdc6
Name: coiled-coil domain containing 6
Synonyms: 2810012H18Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76551
Homologene: 34786
Icam1
Name: intercellular adhesion molecule 1
Synonyms: Ly-47, Icam-1, MALA-2, CD54
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15894
VEGA: 9
HGNC: HGNC:5344
Homologene: 168
Uty
Name: ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
Synonyms: Hydb
Type: Gene
Species: Mouse
Chromosome: Y
NCBI: 22290
Drd3
Name: dopamine receptor D3
Synonyms: D3R, D3 receptor
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13490
VEGA: 16
HGNC: HGNC:3024
Homologene: 623
Tnc
Name: tenascin C
Synonyms: C130033P17Rik, TN, hexabrachion, Hxb, cytotactin, tenascin-C, TN-C
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, Dnahc8, P1-Loop
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Gle1
Name: GLE1 RNA export mediator
Synonyms: 4933405K21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74412
HGNC: HGNC:4315
Homologene: 20379
Pnpla7
Name: patatin-like phospholipase domain containing 7
Synonyms: NRE, E430013P11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241274
Homologene: 62431
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Rbp-3, Irbp
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: E030034C22Rik, Dnahc1, G1-415-19, MDHC7, ferf1, B230373P09Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Skic2
Name: SKI2 subunit of superkiller complex
Synonyms: Ski2w, 4930534J06Rik, Skiv2l
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 108077
Homologene: 123971
Epha5
Name: Eph receptor A5
Synonyms: Rek7, Cek7, bsk, Hek7, Ehk1, Els1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13839
HGNC: HGNC:3389
Homologene: 55824
Med12l
Name: mediator complex subunit 12-like
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329650
Homologene: 43143
Or4a78
Name: olfactory receptor family 4 subfamily A member 78
Synonyms: GA_x6K02T2Q125-51109312-51108356, Olfr1251, MOR231-24_p, MOR231-15P
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259145
Homologene: 74065
1700010I14Rik
Name: RIKEN cDNA 1700010I14 gene
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66931
Homologene: 49841
Vmn2r19
Name: vomeronasal 2, receptor 19
Synonyms: EG232358
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232358
Homologene: 84037
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Naip-rs4, Birc1f, Naip-rs4A
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Slc5a3
Name: solute carrier family 5 (inositol transporters), member 3
Synonyms: Smit1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 53881
Homologene: 31412
Rint1
Name: RAD50 interactor 1
Synonyms: 2810450M21Rik, 1500019C06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72772
Homologene: 11070
Il4ra
Name: interleukin 4 receptor, alpha
Synonyms: IL-4 receptor alpha chain, CD124, Il4r
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16190
HGNC: HGNC:6015
Homologene: 7784
Or1e1c
Name: olfactory receptor family 1 subfamily E member 1C
Synonyms: MOR135-12, GA_x6K02T2P1NL-3535075-3536028, Olfr376
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258924
Homologene: 133579
Thsd7a
Name: thrombospondin, type I, domain containing 7A
Synonyms: LOC330267
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330267
Homologene: 46582
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637908
Homologene: 104040
Ccna1
Name: cyclin A1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12427
HGNC: HGNC:1577
Homologene: 31203
Mmp13
Name: matrix metallopeptidase 13
Synonyms: interstitial collagenase, collagenase-1, Collagenase-3, Clg, MMP-13, Mmp1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17386
VEGA: 9
HGNC: HGNC:7159
Homologene: 20548
Or5b118
Name: olfactory receptor family 5 subfamily B member 118
Synonyms: MOR202-42, GA_x6K02T2RE5P-3803583-3804527, MOR202-26P, Olfr1474
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258123
Homologene: 79417
Mrc2
Name: mannose receptor, C type 2
Synonyms: uPARAP, novel lectin, Endo180
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17534
Homologene: 4408
Gpr137b
Name: G protein-coupled receptor 137B
Synonyms: C80741, 2310041G17Rik, Tm7sf1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 83924
VEGA: 13
Homologene: 2454
Sipa1
Name: signal-induced proliferation associated gene 1
Synonyms: SPA-1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20469
VEGA: 19
Homologene: 7940
Acy3
Name: aminoacylase 3
Synonyms: AA3, 0610006H10Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 71670
VEGA: 19
Homologene: 12401
Shox2
Name: SHOX homeobox 2
Synonyms: 6330543G17Rik, Prx3, Og12x
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20429
Homologene: 68535
4933416C03Rik
Name: RIKEN cDNA 4933416C03 gene
Type: Gene
Species: Mouse
Chromosome: 10
Ctnna3
Name: catenin alpha 3
Synonyms: Catna3, 4930429L08Rik, catenin (cadherin associated protein), alpha 3, alphaT-catenin, Vr22
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216033
HGNC: HGNC:2511
Homologene: 56583
Spata31e4
Name: spermatogenesis associated 31 subfamily E member 4
Synonyms: Gm8765
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 667693
Homologene: 134512
Cimip1
Name: ciliary microtubule inner protein 1
Synonyms: 1700021F07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72221
Homologene: 82371
Vdr
Name: vitamin D (1,25-dihydroxyvitamin D3) receptor
Synonyms: Nr1i1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22337
Homologene: 37297
Popdc3
Name: popeye domain containing 3
Synonyms: Pop3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 78977
Homologene: 32540
Ido1
Name: indoleamine 2,3-dioxygenase 1
Synonyms: Ido, Indo
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 15930
HGNC: HGNC:6059
Homologene: 48082
Or5b3
Name: olfactory receptor family 5 subfamily B member 3
Synonyms: Olfr1469, MOR202-11, GA_x6K02T2RE5P-3743369-3744289
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258690
HGNC: HGNC:8324
Homologene: 133675
Vps45
Name: vacuolar protein sorting 45
Synonyms: mVps45
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22365
Homologene: 5250
Ezhip
Name: EZH inhibitory protein
Synonyms: AU022751
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 102991
Fbxo10
Name: F-box protein 10
Synonyms: LOC269529, FBX10
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269529
Homologene: 19544
Gsta1
Name: glutathione S-transferase, alpha 1 (Ya)
Synonyms: Gst2-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14857
Homologene: 74378
Reep6
Name: receptor accessory protein 6
Synonyms: Dp1l1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70335
Homologene: 133833
Ssr1
Name: signal sequence receptor, alpha
Synonyms: TRAPalpha, SSR
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107513
VEGA: 13
Homologene: 2368
Tmem74
Name: transmembrane protein 74
Synonyms: B230382K22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239408
VEGA: 15
Homologene: 17684
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 155,931,518 bp
  • T to G, chromosome 2 at 13,523,414 bp
  • G to T, chromosome 2 at 24,996,165 bp
  • T to G, chromosome 2 at 29,944,054 bp
  • A to T, chromosome 2 at 89,667,470 bp
  • T to A, chromosome 2 at 173,522,723 bp
  • T to C, chromosome 3 at 55,050,860 bp
  • T to A, chromosome 3 at 59,244,836 bp
  • A to T, chromosome 3 at 66,978,295 bp
  • A to G, chromosome 3 at 96,042,941 bp
  • A to G, chromosome 4 at 45,043,672 bp
  • T to C, chromosome 4 at 56,903,200 bp
  • T to C, chromosome 4 at 64,020,468 bp
  • A to G, chromosome 5 at 17,814,213 bp
  • A to G, chromosome 5 at 23,805,567 bp
  • A to G, chromosome 5 at 84,233,575 bp
  • T to C, chromosome 6 at 12,555,702 bp
  • C to T, chromosome 6 at 112,477,177 bp
  • T to A, chromosome 6 at 123,336,173 bp
  • T to C, chromosome 7 at 12,598,483 bp
  • A to G, chromosome 7 at 17,022,443 bp
  • T to C, chromosome 7 at 98,602,589 bp
  • G to A, chromosome 7 at 125,574,717 bp
  • T to A, chromosome 8 at 24,593,140 bp
  • A to G, chromosome 9 at 7,272,952 bp
  • G to A, chromosome 9 at 21,027,836 bp
  • T to C, chromosome 9 at 78,242,495 bp
  • T to G, chromosome 9 at 123,582,298 bp
  • A to G, chromosome 10 at 45,316,546 bp
  • A to T, chromosome 10 at 64,585,995 bp
  • C to A, chromosome 10 at 70,187,806 bp
  • A to G, chromosome 10 at 80,335,246 bp
  • T to C, chromosome 10 at 116,113,394 bp
  • A to T, chromosome 10 at 117,060,640 bp
  • G to T, chromosome 11 at 30,120,785 bp
  • T to C, chromosome 11 at 57,781,045 bp
  • G to A, chromosome 11 at 73,374,874 bp
  • A to G, chromosome 11 at 105,340,821 bp
  • T to C, chromosome 13 at 13,365,031 bp
  • G to T, chromosome 13 at 37,987,615 bp
  • A to G, chromosome 13 at 50,703,082 bp
  • T to C, chromosome 13 at 100,304,415 bp
  • G to T, chromosome 14 at 31,296,457 bp
  • A to G, chromosome 14 at 33,956,356 bp
  • T to C, chromosome 15 at 43,866,790 bp
  • T to C, chromosome 15 at 66,944,836 bp
  • T to C, chromosome 15 at 97,859,121 bp
  • T to C, chromosome 16 at 43,762,483 bp
  • G to T, chromosome 16 at 92,077,877 bp
  • C to T, chromosome 17 at 8,992,628 bp
  • T to A, chromosome 17 at 30,854,764 bp
  • T to C, chromosome 17 at 34,840,106 bp
  • C to T, chromosome 19 at 3,987,850 bp
  • T to C, chromosome 19 at 5,652,754 bp
  • G to A, chromosome 19 at 13,411,090 bp
  • T to C, chromosome 19 at 13,471,407 bp
  • A to G, chromosome 19 at 27,867,600 bp
  • T to C, chromosome 19 at 41,950,845 bp
  • GTCATCATCATCATC to GTCATCATCATCATCATC, chromosome X at 6,082,591 bp
  • G to A, chromosome X at 73,795,446 bp
  • A to T, chromosome Y at 1,174,741 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1102 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039175-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.