Strain Name:
C57BL/6J-MtgxR0029Btlr/Mmmh
Stock Number:
038323-MU
Citation ID:
RRID:MMRRC_038323-MU
Other Names:
R0029 (G1), C57BL/6J-MtgxR0029Btlr
Major Collection:

Gene Information

Sulf2
Name: sulfatase 2
Synonyms: 2010004N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72043
Homologene: 10313
4930415O20Rik
Name: RIKEN cDNA 4930415O20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 73863
VEGA: 15
HGNC: null
Homologene: 19174
Pard3
Name: par-3 family cell polarity regulator
Synonyms: Pard3a, PAR-3, Par3, ASIP, D8Ertd580e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 93742
Homologene: 10489
Polk
Name: polymerase (DNA directed), kappa
Synonyms: Dinb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 27015
VEGA: 13
HGNC: HGNC:9183
Homologene: 32140
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 4432404J10Rik, 2010005B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66691
Homologene: 32637
Psmb7
Name: proteasome (prosome, macropain) subunit, beta type 7
Synonyms: MC14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19177
HGNC: HGNC:9544
Homologene: 2093
Axin2
Name: axin 2
Synonyms: Axil, Conductin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12006
HGNC: HGNC:904
Homologene: 3420
Cpt1a
Name: carnitine palmitoyltransferase 1a, liver
Synonyms: L-CPT I, Cpt1, CPTI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12894
VEGA: 19
HGNC: HGNC:2328
Homologene: 1413
Crebbp
Name: CREB binding protein
Synonyms: KAT3A, CBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12914
HGNC: HGNC:2348
Homologene: 68393
Lmo7
Name: LIM domain only 7
Synonyms: FBXO20, LOC380928
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Cpa4
Name: carboxypeptidase A4
Synonyms: 1110019K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 71791
Homologene: 56753
Dpy19l2
Name: dpy-19-like 2 (C. elegans)
Synonyms: 4932443J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320752
VEGA: 9
Homologene: 77569
Kirrel2
Name: kirre like nephrin family adhesion molecule 2
Synonyms: NEPH3, C330019F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243911
Homologene: 35249
Hk1
Name: hexokinase 1
Synonyms: Hk1-s, Hk-1, mHk1-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Srpk2
Name: serine/arginine-rich protein specific kinase 2
Synonyms: mSRPK2, WBP6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20817
Homologene: 101663
Abt1
Name: activator of basal transcription 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 30946
Homologene: 134288
Exosc7
Name: exosome component 7
Synonyms: 2610002K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66446
Homologene: 8994
Ubac1
Name: ubiquitin associated domain containing 1
Synonyms: 1110033G07Rik, Ubadc1, Kpc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98766
Homologene: 9409
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225115
Homologene: 25090
Stk38
Name: serine/threonine kinase 38
Synonyms: Ndr1, 5830476G13Rik, 9530097A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 106504
Homologene: 56033
Itga2
Name: integrin alpha 2
Synonyms: DX5, CD49B, VLA-2 receptor, alpha 2 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16398
VEGA: 13
HGNC: HGNC:6137
Homologene: 1662
Mboat4
Name: membrane bound O-acyltransferase domain containing 4
Synonyms: LOC234155, GOAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234155
Homologene: 19272
Ccn4
Name: cellular communication network factor 4
Synonyms: CCN4, Wisp1, Elm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 22402
Homologene: 2883
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Nell1
Name: NEL-like 1
Synonyms: B230343H07Rik, l7R6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 338352
HGNC: HGNC:7750
Homologene: 4486
Avl9
Name: AVL9 cell migration associated
Synonyms: 5830411G16Rik, D730049P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 78937
Homologene: 62425
Ralgps1
Name: Ral GEF with PH domain and SH3 binding motif 1
Synonyms: RALGEF2, 5830418G11Rik, RALGPS1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241308
Homologene: 65163
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: A930015H12Rik, SPACR, IMP150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Per2
Name: period circadian clock 2
Synonyms: mPer2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18627
HGNC: HGNC:8846
Homologene: 7885
Tmem63a
Name: transmembrane protein 63a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 208795
Homologene: 101673
Ciz1
Name: CDKN1A interacting zinc finger protein 1
Synonyms: 2900056O04Rik, 0610038H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68379
Homologene: 8112
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269356
Homologene: 12931
Vmn2r2
Name: vomeronasal 2, receptor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 100125586
HGNC: null
Homologene: 129753
Prmt6
Name: protein arginine N-methyltransferase 6
Synonyms: Hrmt1l6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99890
Homologene: 10024
Lrpap1
Name: low density lipoprotein receptor-related protein associated protein 1
Synonyms: RAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16976
HGNC: HGNC:6701
Homologene: 37612
Tcaf2
Name: TRPM8 channel-associated factor 2
Synonyms: Fam115c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232748
Homologene: 17147
Il23r
Name: interleukin 23 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 209590
Homologene: 16930
Fgd5
Name: FYVE, RhoGEF and PH domain containing 5
Synonyms: ZFYVE23, C330025N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232237
Homologene: 27798
Usp29
Name: ubiquitin specific peptidase 29
Synonyms: Ocat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57775
Homologene: 49641
Sult2a3
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
Synonyms: Gm6955
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 629203
Homologene: 37741
Vmn1r179
Name: vomeronasal 1 receptor 179
Synonyms: V1rd17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 404286
HGNC: null
Homologene: 134022
Abca15
Name: ATP-binding cassette, sub-family A (ABC1), member 15
Synonyms: 4930500I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320631
HGNC: null
Homologene: 87255
Nadsyn1
Name: NAD synthetase 1
Synonyms: 9130012B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 78914
Homologene: 6098
Olfr955
Name: olfactory receptor 955
Synonyms: GA_x6K02T2PVTD-33167297-33166353, MOR171-34, MOR171-50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258242
VEGA: 9
HGNC: null
Homologene: 133698
Fbxw28
Name: F-box and WD-40 domain protein 28
Synonyms: Gm9337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 668758
Homologene: 110776
Anapc15-ps
Name: anaphase prompoting complex C subunit 15, pseudogene
Synonyms: Gm6843
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 628119
VEGA: 10
HGNC: null
Homologene: null
Gas7
Name: growth arrest specific 7
Synonyms: B230343A10Rik, Gas7-cb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14457
HGNC: HGNC:4169
Homologene: 69015
Tmem132e
Name: transmembrane protein 132E
Synonyms: LOC270893
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 270893
Homologene: 41524
Vmn1r204
Name: vomeronasal 1 receptor 204
Synonyms: Gm11301
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 632793
HGNC: null
Homologene: 110880
Phf11c
Name: PHD finger protein 11C
Synonyms: Gm6907
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 628705
Homologene: 87807
Olfr209
Name: olfactory receptor 209
Synonyms: GA_x54KRFPKG5P-55580232-55579315, Olfr208, MOR182-6, MOR182-6, GA_x54KRFPKG5P-55590495-55589578
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 404311
HGNC: null
Homologene: 133040
Slc26a2
Name: solute carrier family 26 (sulfate transporter), member 2
Synonyms: ST-OB, Dtd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13521
Homologene: 73876
Lipm
Name: lipase, family member M
Synonyms: Lipl3, 4632427C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 78753
VEGA: 19
Homologene: 28267
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 91,423,712 bp
  • A to G, chromosome 1 at 180,962,466 bp
  • G to T, chromosome 2 at 26,021,443 bp
  • A to G, chromosome 2 at 32,371,419 bp
  • A to T, chromosome 2 at 33,141,019 bp
  • T to A, chromosome 2 at 34,678,141 bp
  • T to A, chromosome 2 at 38,633,907 bp
  • T to C, chromosome 2 at 76,766,506 bp
  • A to G, chromosome 2 at 130,688,054 bp
  • T to C, chromosome 2 at 166,116,973 bp
  • T to C, chromosome 3 at 64,116,944 bp
  • T to C, chromosome 3 at 110,249,898 bp
  • T to A, chromosome 5 at 23,565,101 bp
  • T to C, chromosome 5 at 35,097,677 bp
  • A to G, chromosome 6 at 30,585,045 bp
  • A to T, chromosome 6 at 42,630,159 bp
  • G to T, chromosome 6 at 56,736,483 bp
  • A to C, chromosome 6 at 67,478,945 bp
  • A to G, chromosome 6 at 92,067,558 bp
  • T to C, chromosome 7 at 6,961,581 bp
  • T to A, chromosome 7 at 14,073,074 bp
  • A to T, chromosome 7 at 23,929,205 bp
  • A to G, chromosome 7 at 30,453,165 bp
  • G to A, chromosome 7 at 50,120,715 bp
  • T to C, chromosome 7 at 120,346,002 bp
  • G to C, chromosome 7 at 143,806,078 bp
  • T to G, chromosome 8 at 34,120,209 bp
  • G to T, chromosome 8 at 127,426,758 bp
  • T to A, chromosome 9 at 24,558,101 bp
  • T to A, chromosome 9 at 39,470,660 bp
  • T to C, chromosome 9 at 80,398,371 bp
  • T to A, chromosome 9 at 109,328,289 bp
  • A to T, chromosome 9 at 123,119,237 bp
  • T to C, chromosome 10 at 62,315,394 bp
  • A to G, chromosome 10 at 95,672,995 bp
  • A to G, chromosome 11 at 67,643,337 bp
  • A to T, chromosome 11 at 82,444,761 bp
  • A to G, chromosome 11 at 108,924,047 bp
  • A to G, chromosome 13 at 22,556,418 bp
  • A to T, chromosome 13 at 23,422,508 bp
  • G to A, chromosome 13 at 96,516,670 bp
  • G to A, chromosome 13 at 114,870,496 bp
  • T to C, chromosome 14 at 59,384,915 bp
  • T to C, chromosome 14 at 101,933,921 bp
  • C to T, chromosome 15 at 66,912,864 bp
  • T to C, chromosome 15 at 98,585,309 bp
  • T to C, chromosome 16 at 4,117,443 bp
  • T to C, chromosome 16 at 59,361,541 bp
  • T to C, chromosome 17 at 28,982,138 bp
  • C to A, chromosome 18 at 5,063,286 bp
  • G to A, chromosome 18 at 61,202,310 bp
  • A to G, chromosome 19 at 3,381,674 bp
  • T to C, chromosome 19 at 34,116,548 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0029 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038323-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.