Strain Name:
C57BL/6J-MtgxR0029Btlr/Mmmh
Stock Number:
038323-MU
Citation ID:
RRID:MMRRC_038323-MU
Other Names:
R0029 (G1), C57BL/6J-MtgxR0029Btlr
Major Collection:

Strain Information

Sulf2
Name: sulfatase 2
Synonyms: 2010004N24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72043
Homologene: 10313
Spmip11
Name: sperm microtubule inner protein 11
Synonyms: Tex49, 4930415O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73863
VEGA: 15
Homologene: 19174
Pard3
Name: par-3 family cell polarity regulator
Synonyms: ASIP, PAR-3, D8Ertd580e, Pard3a, Par3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 93742
Homologene: 10489
Polk
Name: polymerase (DNA directed), kappa
Synonyms: Dinb1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 27015
VEGA: 13
HGNC: HGNC:9183
Homologene: 32140
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 4432404J10Rik, 2010005B09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66691
Homologene: 32637
Psmb7
Name: proteasome (prosome, macropain) subunit, beta type 7
Synonyms: MC14
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19177
HGNC: HGNC:9544
Homologene: 2093
Axin2
Name: axin 2
Synonyms: Conductin, Axil
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12006
HGNC: HGNC:904
Homologene: 3420
Cpt1a
Name: carnitine palmitoyltransferase 1a, liver
Synonyms: L-CPT I, Cpt1, CPTI
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12894
VEGA: 19
HGNC: HGNC:2328
Homologene: 1413
Crebbp
Name: CREB binding protein
Synonyms: KAT3A, CBP
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12914
HGNC: HGNC:2348
Homologene: 68393
Lmo7
Name: LIM domain only 7
Synonyms: LOC380928, FBXO20
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Cpa4
Name: carboxypeptidase A4
Synonyms: 1110019K20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71791
Homologene: 56753
Dpy19l2
Name: dpy-19 like 2
Synonyms: 4932443J21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320752
VEGA: 9
Homologene: 77569
Kirrel2
Name: kirre like nephrin family adhesion molecule 2
Synonyms: NEPH3, C330019F22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243911
Homologene: 35249
Hk1
Name: hexokinase 1
Synonyms: Hk-1, mHk1-s, Hk1-s
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Srpk2
Name: serine/arginine-rich protein specific kinase 2
Synonyms: WBP6, mSRPK2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20817
Homologene: 101663
Abt1
Name: activator of basal transcription 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 30946
Homologene: 134288
Exosc7
Name: exosome component 7
Synonyms: 2610002K22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66446
Homologene: 8994
Ubac1
Name: ubiquitin associated domain containing 1
Synonyms: 1110033G07Rik, Kpc2, Ubadc1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98766
Homologene: 9409
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225115
Homologene: 25090
Stk38
Name: serine/threonine kinase 38
Synonyms: 5830476G13Rik, 9530097A09Rik, Ndr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106504
Homologene: 56033
Itga2
Name: integrin alpha 2
Synonyms: DX5, VLA-2 receptor, alpha 2 subunit, CD49B
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16398
VEGA: 13
HGNC: HGNC:6137
Homologene: 1662
Mboat4
Name: membrane bound O-acyltransferase domain containing 4
Synonyms: GOAT, LOC234155
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234155
Homologene: 19272
Ccn4
Name: cellular communication network factor 4
Synonyms: Elm1, Wisp1, CCN4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22402
Homologene: 2883
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Nell1
Name: NEL-like 1
Synonyms: l7R6, B230343H07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 338352
HGNC: HGNC:7750
Homologene: 4486
Avl9
Name: AVL9 cell migration associated
Synonyms: D730049P16Rik, 5830411G16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78937
Homologene: 62425
Ralgps1
Name: Ral GEF with PH domain and SH3 binding motif 1
Synonyms: RALGPS1A, RALGEF2, 5830418G11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241308
Homologene: 65163
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: A930015H12Rik, IMP150, SPACR
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Per2
Name: period circadian clock 2
Synonyms: mPer2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18627
HGNC: HGNC:8846
Homologene: 7885
Tmem63a
Name: transmembrane protein 63a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208795
Homologene: 101673
Ciz1
Name: CDKN1A interacting zinc finger protein 1
Synonyms: 0610038H21Rik, 2900056O04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68379
Homologene: 8112
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269356
Homologene: 12931
Vmn2r2
Name: vomeronasal 2, receptor 2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100125586
Homologene: 129753
Prmt6
Name: protein arginine N-methyltransferase 6
Synonyms: Hrmt1l6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99890
Homologene: 10024
Lrpap1
Name: low density lipoprotein receptor-related protein associated protein 1
Synonyms: RAP
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16976
HGNC: HGNC:6701
Homologene: 37612
Tcaf2
Name: TRPM8 channel-associated factor 2
Synonyms: Fam115c
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232748
Homologene: 17147
Il23r
Name: interleukin 23 receptor
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209590
Homologene: 16930
Fgd5
Name: FYVE, RhoGEF and PH domain containing 5
Synonyms: ZFYVE23, C330025N11Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232237
Homologene: 27798
Usp29
Name: ubiquitin specific peptidase 29
Synonyms: Ocat
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57775
Homologene: 49641
Sult2a3
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
Synonyms: Gm6955
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 629203
Homologene: 37741
Vmn1r179
Name: vomeronasal 1 receptor 179
Synonyms: V1rd17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404286
Homologene: 134022
Abca15
Name: ATP-binding cassette, sub-family A member 15
Synonyms: 4930500I12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320631
Homologene: 87255
Nadsyn1
Name: NAD synthetase 1
Synonyms: 9130012B15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78914
Homologene: 6098
Or8g35
Name: olfactory receptor family 8 subfamily G member 35
Synonyms: MOR171-34, MOR171-50, GA_x6K02T2PVTD-33167297-33166353, Olfr955
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258242
VEGA: 9
Homologene: 133698
Fbxw28
Name: F-box and WD-40 domain protein 28
Synonyms: Gm9337
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 668758
Homologene: 110776
Anapc15-ps
Name: anaphase promoting complex C subunit 15, pseudogene
Synonyms: Gm6843
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628119
VEGA: 10
Gas7
Name: growth arrest specific 7
Synonyms: Gas7-cb, B230343A10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14457
HGNC: HGNC:4169
Homologene: 69015
Tmem132e
Name: transmembrane protein 132E
Synonyms: LOC270893
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 270893
Homologene: 41524
Vmn1r204
Name: vomeronasal 1 receptor 204
Synonyms: Gm11301
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 632793
Homologene: 110880
Phf11c
Name: PHD finger protein 11C
Synonyms: Gm6907
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 628705
Homologene: 87807
Or5ac25
Name: olfactory receptor family 5 subfamily AC member 25
Synonyms: GA_x54KRFPKG5P-55590495-55589578, GA_x54KRFPKG5P-55570276-55569359, MOR182-6, GA_x54KRFPKG5P-55580232-55579315, MOR182-6, MOR182-9, Olfr209, Olfr208, Olfr207
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 404311
Homologene: 133040
Slc26a2
Name: solute carrier family 26 (sulfate transporter), member 2
Synonyms: Dtd, ST-OB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13521
Homologene: 73876
Lipm
Name: lipase, family member M
Synonyms: Lipl3, 4632427C23Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78753
VEGA: 19
Homologene: 28267
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 91,423,712 bp
  • A to G, chromosome 1 at 180,962,466 bp
  • G to T, chromosome 2 at 26,021,443 bp
  • A to G, chromosome 2 at 32,371,419 bp
  • A to T, chromosome 2 at 33,141,019 bp
  • T to A, chromosome 2 at 34,678,141 bp
  • T to A, chromosome 2 at 38,633,907 bp
  • T to C, chromosome 2 at 76,766,506 bp
  • A to G, chromosome 2 at 130,688,054 bp
  • T to C, chromosome 2 at 166,116,973 bp
  • T to C, chromosome 3 at 64,116,944 bp
  • T to C, chromosome 3 at 110,249,898 bp
  • T to A, chromosome 5 at 23,565,101 bp
  • T to C, chromosome 5 at 35,097,677 bp
  • A to G, chromosome 6 at 30,585,045 bp
  • A to T, chromosome 6 at 42,630,159 bp
  • G to T, chromosome 6 at 56,736,483 bp
  • A to C, chromosome 6 at 67,478,945 bp
  • A to G, chromosome 6 at 92,067,558 bp
  • T to C, chromosome 7 at 6,961,581 bp
  • T to A, chromosome 7 at 14,073,074 bp
  • A to T, chromosome 7 at 23,929,205 bp
  • A to G, chromosome 7 at 30,453,165 bp
  • G to A, chromosome 7 at 50,120,715 bp
  • T to C, chromosome 7 at 120,346,002 bp
  • G to C, chromosome 7 at 143,806,078 bp
  • T to G, chromosome 8 at 34,120,209 bp
  • G to T, chromosome 8 at 127,426,758 bp
  • T to A, chromosome 9 at 24,558,101 bp
  • T to A, chromosome 9 at 39,470,660 bp
  • T to C, chromosome 9 at 80,398,371 bp
  • T to A, chromosome 9 at 109,328,289 bp
  • A to T, chromosome 9 at 123,119,237 bp
  • T to C, chromosome 10 at 62,315,394 bp
  • A to G, chromosome 10 at 95,672,995 bp
  • A to G, chromosome 11 at 67,643,337 bp
  • A to T, chromosome 11 at 82,444,761 bp
  • A to G, chromosome 11 at 108,924,047 bp
  • A to G, chromosome 13 at 22,556,418 bp
  • A to T, chromosome 13 at 23,422,508 bp
  • G to A, chromosome 13 at 96,516,670 bp
  • G to A, chromosome 13 at 114,870,496 bp
  • T to C, chromosome 14 at 59,384,915 bp
  • T to C, chromosome 14 at 101,933,921 bp
  • C to T, chromosome 15 at 66,912,864 bp
  • T to C, chromosome 15 at 98,585,309 bp
  • T to C, chromosome 16 at 4,117,443 bp
  • T to C, chromosome 16 at 59,361,541 bp
  • T to C, chromosome 17 at 28,982,138 bp
  • C to A, chromosome 18 at 5,063,286 bp
  • G to A, chromosome 18 at 61,202,310 bp
  • A to G, chromosome 19 at 3,381,674 bp
  • T to C, chromosome 19 at 34,116,548 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0029 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038323-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.