Strain Name:
C57BL/6J-MtgxR0034Btlr/Mmmh
Stock Number:
038328-MU
Citation ID:
RRID:MMRRC_038328-MU
Other Names:
R0034 (G1), C57BL/6J-MtgxR0034Btlr
Major Collection:

Strain Information

Kifc2
Name: kinesin family member C2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16581
VEGA: 15
Homologene: 7800
Ubn2
Name: ubinuclein 2
Synonyms: D130059P03Rik, 2900060J04Rik, 6030408G03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320538
Homologene: 45564
Chrna7
Name: cholinergic receptor, nicotinic, alpha polypeptide 7
Synonyms: alpha7-nAChR, alpha7 nicotinic receptor, alpha7, Acra7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11441
Homologene: 593
Cd14
Name: CD14 antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12475
VEGA: 18
HGNC: HGNC:1628
Homologene: 493
Pax4
Name: paired box 4
Synonyms: Pax-4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18506
HGNC: HGNC:8618
Homologene: 4515
Sgpl1
Name: sphingosine phosphate lyase 1
Synonyms: D10Xrf456
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20397
Homologene: 2897
Gnb1
Name: guanine nucleotide binding protein (G protein), beta 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14688
HGNC: HGNC:4396
Homologene: 55532
Map2k4
Name: mitogen-activated protein kinase kinase 4
Synonyms: Serk1, JNKK1, Sek1, MKK4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26398
HGNC: HGNC:6844
Homologene: 48159
Sbno2
Name: strawberry notch 2
Synonyms: Stno
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216161
VEGA: 10
Homologene: 8981
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 2900036C23Rik, 2810413I22Rik, 2410152H17Rik, 6030449K19Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66315
Homologene: 10778
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: AP-3, Hps2, beta3A, recombination induced mutation 2, rim2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Kif15
Name: kinesin family member 15
Synonyms: 3930402I10Rik, 3110023M17Rik, HKLP2, N-10 kinesin, Knsl7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 209737
VEGA: 9
Homologene: 23210
Heatr5a
Name: HEAT repeat containing 5A
Synonyms: D930036F22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320487
VEGA: 12
Homologene: 19635
Rapgef1
Name: Rap guanine nucleotide exchange factor (GEF) 1
Synonyms: Grf2, 4932418O06Rik, C3G
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 107746
HGNC: HGNC:4568
Homologene: 50501
Gabpb1
Name: GA repeat binding protein, beta 1
Synonyms: E4Tf1B, GABPB1-2, NRF2B1, E4TF1, NRF2B2, GABPB1-1, BABPB2, E4TF1-53, E4TF1-47
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14391
HGNC: HGNC:4074
Homologene: 7723
Klf12
Name: Kruppel-like transcription factor 12
Synonyms: B130052C06Rik, AP-2rep, D530033K05Rik, 2700063E05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16597
VEGA: 14
HGNC: HGNC:6346
Homologene: 21417
Kif26a
Name: kinesin family member 26A
Synonyms: N-11 kinesin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 668303
Homologene: 18970
Tfrc
Name: transferrin receptor
Synonyms: Mtvr-1, TfR1, Mtvr1, p90, CD71, 2610028K12Rik, E430033M20Rik, Trfr
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 22042
Homologene: 2429
Eef1d
Name: eukaryotic translation elongation factor 1 delta
Synonyms: 5730529A16Rik, 1700026P12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66656
HGNC: HGNC:3211
Homologene: 23404
Sec1
Name: secretory blood group 1
Synonyms: GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase FUT-III, Fut3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56546
Homologene: 431
Sgk3
Name: serum/glucocorticoid regulated kinase 3
Synonyms: A330005P07Rik, cytokine-independent survival kinase, 2510015P22Rik, fy, Cisk
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170755
Homologene: 56582
Cd300lb
Name: CD300 molecule like family member B
Synonyms: LOC217304, Clm7, LMIR5, CLM-7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217304
Homologene: 18374
Rbm43
Name: RNA binding motif protein 43
Synonyms: 0610033I05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71684
Homologene: 12715
Trap1
Name: TNF receptor-associated protein 1
Synonyms: 2410002K23Rik, HSP75
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 68015
Homologene: 9457
Zfp949
Name: zinc finger protein 949
Synonyms: 4930422I07Rik, Nczf
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71640
Homologene: 129930
Zfta
Name: zinc finger translocation associated
Synonyms: 2700081O15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 108899
Homologene: 52179
Cep152
Name: centrosomal protein 152
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99100
Homologene: 37159
Stra6
Name: stimulated by retinoic acid gene 6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20897
Homologene: 7554
Tsku
Name: tsukushi, small leucine rich proteoglycan
Synonyms: 9530051K01Rik, Lrrc54
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244152
Homologene: 41045
Gata4
Name: GATA binding protein 4
Synonyms: Gata-4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14463
HGNC: HGNC:4173
Homologene: 1551
Kcng3
Name: potassium voltage-gated channel, subfamily G, member 3
Synonyms: Kv10.1a, KV6.3, Kv10.1b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 225030
VEGA: 17
Homologene: 15168
Trpc1
Name: transient receptor potential cation channel, subfamily C, member 1
Synonyms: Mtrp1, Trp1, Trrp1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22063
Homologene: 2478
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: b2b1554Clo, A2mr, CD91
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
C030017K20Rik
Name: RIKEN cDNA C030017K20 gene
Synonyms: LOC381581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Col28a1
Name: collagen, type XXVIII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213945
Homologene: 66345
Plcz1
Name: phospholipase C, zeta 1
Synonyms: 1700041H07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 114875
Homologene: 23815
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Ltbp1
Name: latent transforming growth factor beta binding protein 1
Synonyms: 9430031G15Rik, LTBP-1, b2b1000Clo, Ltbp1L
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268977
HGNC: HGNC:6714
Homologene: 522
Plb1
Name: phospholipase B1
Synonyms: 4632413E21Rik, 4930433E17Rik, 4930539A06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665270
Homologene: 82108
Aplp1
Name: amyloid beta precursor like protein 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11803
HGNC: HGNC:597
Homologene: 68447
Usp50
Name: ubiquitin specific peptidase 50
Synonyms: 4930511O11Rik, 1700086G18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75083
Homologene: 75281
Dnaaf9
Name: dynein axonemal assembly factor 9
Synonyms: 4930402H24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228602
Homologene: 12623
Angpt4
Name: angiopoietin 4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11602
HGNC: HGNC:487
Homologene: 36302
Vmn2r1
Name: vomeronasal 2, receptor 1
Synonyms: EG56544, V2r83
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56544
Homologene: 84832
Trim14
Name: tripartite motif-containing 14
Synonyms: 5830400N10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74735
Homologene: 13241
Zscan20
Name: zinc finger and SCAN domains 20
Synonyms: Zfp31
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269585
Homologene: 51463
Poln
Name: DNA polymerase N
Synonyms: POL4P
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 272158
Homologene: 131253
Ppp2r2c
Name: protein phosphatase 2, regulatory subunit B, gamma
Synonyms: IMYPNO1, PR52, 6330548O06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269643
HGNC: HGNC:9306
Homologene: 36386
Exoc1l
Name: exocyst complex component 1 like
Synonyms: Gm7271
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 639545
Asns
Name: asparagine synthetase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27053
HGNC: HGNC:753
Homologene: 69113
Nat8f5
Name: N-acetyltransferase 8 (GCN5-related) family member 5
Synonyms: 1810018F03Rik, Cml5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69049
Homologene: 87019
Uroc1
Name: urocanase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243537
Homologene: 76629
Vmn1r69
Name: vomeronasal 1 receptor 69
Synonyms: V1re9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 252904
Homologene: 120153
Gm5114
Name: predicted gene 5114
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330513
Homologene: 45597
Or51m1
Name: olfactory receptor family 51 subfamily M member 1
Synonyms: MOR3-1, GA_x6K02T2PBJ9-6662699-6663658, Olfr631
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258961
Homologene: 64935
9430038I01Rik
Name: RIKEN cDNA 9430038I01 gene
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77252
Homologene: 130777
Poteg
Name: POTE ankyrin domain family, member G
Synonyms: 4921537P18Rik, 4930456F22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70952
Homologene: 134158
Kif9
Name: kinesin family member 9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16578
Homologene: 65620
Samd3
Name: sterile alpha motif domain containing 3
Synonyms: LOC268288
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 268288
VEGA: 10
Homologene: 67991
Haspin
Name: histone H3 associated protein kinase
Synonyms: Gsg2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14841
Homologene: 49236
Faap100
Name: Fanconi anemia core complex associated protein 100
Synonyms: 2310003H01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71885
Homologene: 69394
Tmem30b
Name: transmembrane protein 30B
Synonyms: 9130011B11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238257
VEGA: 12
Homologene: 133755
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: X83337, ESTM15, 1810073P09Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75607
Homologene: 19155
Atxn7
Name: ataxin 7
Synonyms: A430107N12Rik, ataxin-7, Sca7
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 246103
VEGA: 14
Homologene: 30967
Rhobtb2
Name: Rho-related BTB domain containing 2
Synonyms: E130206H14Rik, Dbc2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 246710
VEGA: 14
Homologene: 22873
Farp1
Name: FERM, ARH/RhoGEF and pleckstrin domain protein 1
Synonyms: Cdep
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 223254
HGNC: HGNC:3591
Homologene: 38098
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Pcdhb5
Name: protocadherin beta 5
Synonyms: Pcdhb4A, PcdhbE
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93876
HGNC: HGNC:8689
Homologene: 75103
Slc22a26
Name: solute carrier family 22 (organic cation transporter), member 26
Synonyms: BC014805
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 236149
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 9,885,677 bp
  • C to A, chromosome 2 at 29,724,768 bp
  • A to T, chromosome 2 at 51,925,710 bp
  • C to T, chromosome 2 at 125,583,893 bp
  • C to T, chromosome 2 at 126,658,534 bp
  • T to C, chromosome 2 at 126,777,975 bp
  • T to C, chromosome 2 at 130,736,572 bp
  • C to T, chromosome 2 at 151,929,391 bp
  • T to A, chromosome 3 at 64,090,014 bp
  • A to G, chromosome 4 at 46,523,627 bp
  • T to C, chromosome 4 at 128,585,662 bp
  • C to T, chromosome 4 at 155,460,887 bp
  • T to A, chromosome 4 at 155,551,689 bp
  • G to T, chromosome 5 at 32,273,113 bp
  • A to C, chromosome 5 at 34,115,418 bp
  • A to G, chromosome 5 at 36,927,539 bp
  • A to G, chromosome 5 at 76,516,530 bp
  • G to A, chromosome 6 at 7,676,299 bp
  • T to A, chromosome 6 at 8,175,708 bp
  • T to C, chromosome 6 at 28,442,449 bp
  • T to C, chromosome 6 at 38,491,406 bp
  • C to A, chromosome 6 at 85,817,886 bp
  • T to C, chromosome 6 at 90,345,310 bp
  • A to T, chromosome 6 at 140,020,448 bp
  • T to A, chromosome 7 at 10,580,811 bp
  • A to C, chromosome 7 at 30,444,442 bp
  • A to G, chromosome 7 at 39,408,858 bp
  • A to G, chromosome 7 at 45,679,335 bp
  • T to G, chromosome 7 at 63,148,606 bp
  • T to C, chromosome 7 at 98,352,663 bp
  • T to C, chromosome 7 at 103,929,501 bp
  • C to T, chromosome 7 at 137,387,592 bp
  • A to G, chromosome 8 at 27,462,077 bp
  • G to A, chromosome 9 at 58,151,469 bp
  • A to T, chromosome 9 at 88,567,640 bp
  • A to G, chromosome 9 at 95,749,761 bp
  • G to A, chromosome 9 at 110,519,611 bp
  • A to T, chromosome 9 at 122,999,285 bp
  • G to A, chromosome 10 at 26,271,500 bp
  • A to T, chromosome 10 at 61,102,613 bp
  • A to C, chromosome 10 at 80,058,340 bp
  • A to T, chromosome 10 at 127,545,651 bp
  • A to G, chromosome 11 at 65,719,611 bp
  • G to A, chromosome 11 at 73,138,218 bp
  • C to T, chromosome 11 at 114,928,399 bp
  • A to T, chromosome 11 at 120,372,147 bp
  • A to G, chromosome 12 at 51,925,172 bp
  • T to C, chromosome 12 at 73,546,005 bp
  • T to C, chromosome 12 at 112,168,963 bp
  • G to T, chromosome 13 at 49,068,080 bp
  • T to C, chromosome 13 at 94,479,885 bp
  • A to T, chromosome 14 at 14,100,846 bp
  • C to A, chromosome 14 at 63,201,484 bp
  • T to C, chromosome 14 at 69,788,688 bp
  • A to G, chromosome 14 at 99,987,429 bp
  • A to G, chromosome 14 at 121,255,429 bp
  • G to A, chromosome 15 at 44,504,009 bp
  • T to C, chromosome 15 at 75,902,959 bp
  • G to T, chromosome 15 at 76,667,100 bp
  • A to T, chromosome 16 at 4,069,030 bp
  • T to A, chromosome 16 at 32,615,396 bp
  • A to C, chromosome 16 at 56,153,570 bp
  • T to A, chromosome 17 at 75,047,568 bp
  • T to A, chromosome 17 at 83,588,383 bp
  • A to G, chromosome 18 at 31,960,860 bp
  • A to G, chromosome 18 at 36,726,235 bp
  • A to G, chromosome 18 at 37,322,084 bp
  • C to A, chromosome 19 at 7,420,359 bp
  • A to G, chromosome 19 at 7,802,253 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0034 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038328-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.