Strain Name:
C57BL/6J-MtgxR0067Btlr/Mmmh
Stock Number:
038358-MU
Citation ID:
RRID:MMRRC_038358-MU
Other Names:
R0067 (G1), C57BL/6J-MtgxR0067Btlr
Major Collection:

Strain Information

Limch1
Name: LIM and calponin homology domains 1
Synonyms: 3732412D22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77569
Homologene: 18953
Satb1
Name: special AT-rich sequence binding protein 1
Synonyms: 2610306G12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20230
Homologene: 2232
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, trabeculin alpha, Acf7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Glo1
Name: glyoxalase 1
Synonyms: Glo1-s, Qglo, 1110008E19Rik, Glo1-r, 2510049H23Rik, 0610009E22Rik, Glo-1s, Glo-1r, Glo-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 109801
VEGA: 17
HGNC: HGNC:4323
Homologene: 4880
Cep97
Name: centrosomal protein 97
Synonyms: 2810403B08Rik, E130116N02Rik, 4932439K18Rik, Lrriq2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74201
Homologene: 11579
Ticrr
Name: TOPBP1-interacting checkpoint and replication regulator
Synonyms: 5730590G19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77011
Homologene: 67120
Ube3c
Name: ubiquitin protein ligase E3C
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100763
Homologene: 8783
Clasp2
Name: CLIP associating protein 2
Synonyms: CLASP2beta, 1500004F14Rik, CLASP2gamma, 8030404L10Rik, CLASP2alpha, CLASP2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76499
VEGA: 9
Homologene: 24944
Ptbp2
Name: polypyrimidine tract binding protein 2
Synonyms: brPTB
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56195
Homologene: 23162
Hdac4
Name: histone deacetylase 4
Synonyms: 4932408F19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208727
Homologene: 55946
Hunk
Name: hormonally upregulated Neu-associated kinase
Synonyms: Mak-v, Bstk1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 26559
VEGA: 16
Homologene: 8742
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: 2810431N21Rik, PEPP2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 109135
Homologene: 10377
Mtrex
Name: Mtr4 exosome RNA helicase
Synonyms: Skiv2l2, 2610528A15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72198
VEGA: 13
Homologene: 6257
Rps6ka5
Name: ribosomal protein S6 kinase, polypeptide 5
Synonyms: 6330404E13Rik, 3110005L17Rik, MSK1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73086
VEGA: 12
Homologene: 48302
Tshr
Name: thyroid stimulating hormone receptor
Synonyms: hyt, pet, hypothroid
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 22095
Homologene: 315
Rasgrp1
Name: RAS guanyl releasing protein 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19419
HGNC: HGNC:9878
Homologene: 4195
Slitrk6
Name: SLIT and NTRK-like family, member 6
Synonyms: 4832410J21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239250
VEGA: 14
Homologene: 12986
Mc5r
Name: melanocortin 5 receptor
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17203
VEGA: 18
HGNC: HGNC:6933
Homologene: 4321
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: 2310001H13Rik, hyrt
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67095
Homologene: 25103
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: NMHC II-C, 2400004E04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71960
Homologene: 23480
Zzz3
Name: zinc finger, ZZ domain containing 3
Synonyms: 6430567E01Rik, 3110065C23Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 108946
Homologene: 9182
Mcf2l
Name: mcf.2 transforming sequence-like
Synonyms: C130040G20Rik, Dbs
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17207
Homologene: 11804
Eva1c
Name: eva-1 homolog C
Synonyms: 4931408A02Rik, Fam176c, 1700092M14Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70967
Homologene: 14383
Map2
Name: microtubule-associated protein 2
Synonyms: Mtap2, G1-397-34, repro4, MAP-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Gps2
Name: G protein pathway suppressor 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56310
HGNC: HGNC:4550
Homologene: 49599
Spats2
Name: spermatogenesis associated, serine-rich 2
Synonyms: 2700012F11Rik, 59kDa, Scr59, p59scr
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72572
VEGA: 15
Homologene: 11314
Memo1
Name: mediator of cell motility 1
Synonyms: 0610016J10Rik, D930048L02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 76890
VEGA: 17
Homologene: 6272
AW209491
Name: expressed sequence AW209491
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105351
VEGA: 13
Homologene: 11439
Rnf214
Name: ring finger protein 214
Synonyms: D130054N24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235315
Homologene: 109357
Zfc3h1
Name: zinc finger, C3H1-type containing
Synonyms: Psrc2, Ccdc131
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216345
Homologene: 17017
Dennd1c
Name: DENN domain containing 1C
Synonyms: 4432409M07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70785
VEGA: 17
Homologene: 11773
Fam151b
Name: family with sequence similarity 151, member B
Synonyms: 4930405M20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73942
VEGA: 13
Homologene: 17853
Ush2a
Name: usherin
Synonyms: MUSH2A, A930037M10Rik, LOC381317, LOC269160, Ushrn, A930011D15Rik, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 545030
Homologene: 83473
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: Cchl1a, D-LTCC, Cacnl1a2, 8430418G19Rik, Cav1.3alpha1, Cchl1a2, C79217
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Slc36a2
Name: solute carrier family 36 (proton/amino acid symporter), member 2
Synonyms: A530067G19Rik, Tramd1, PAT2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246049
Homologene: 72100
Eml1
Name: echinoderm microtubule associated protein like 1
Synonyms: ELP79, heco, 1110008N23Rik, A930030P13Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68519
HGNC: HGNC:3330
Homologene: 20931
Unc79
Name: unc-79 homolog
Synonyms: 9030205A07Rik, Mlca3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217843
Homologene: 41397
Adamts9
Name: ADAM metallopeptidase with thrombospondin type 1 motif 9
Synonyms: 1810011L16Rik, E030027K14Rik, 8430403M15Rik, UND3, UND4, Mhdaund3, Mhdaund4, Gsfund3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101401
Homologene: 18821
Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Synonyms: D430008P04Rik, tie-1, TIE
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21846
Homologene: 3957
Sp140l2
Name: Sp140 nuclear body protein like 2
Synonyms: OTTMUSG00000029174, C130026I21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 620078
Homologene: 131208
Trmt1l
Name: tRNA methyltransferase 1 like
Synonyms: Trm1-like, 1190005F20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98685
Homologene: 12801
Stkld1
Name: serine/threonine kinase-like domain containing 1
Synonyms: LOC279029, Gm711
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 279029
Homologene: 19586
Gm13941
Name: predicted gene 13941
Type: Gene
Species: Mouse
Chromosome: 2
L3mbtl1
Name: L3MBTL1 histone methyl-lysine binding protein
Synonyms: L3MBTL1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241764
Homologene: 41846
Skint10
Name: selection and upkeep of intraepithelial T cells 10
Synonyms: A030001H23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230613
Homologene: 136292
Rtn2
Name: reticulon 2 (Z-band associated protein)
Synonyms: Nspl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20167
Homologene: 32180
Coq8b
Name: coenzyme Q8B
Synonyms: 0610012P18Rik, Adck4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76889
Homologene: 86731
Unc13a
Name: unc-13 homolog A
Synonyms: Munc13-1, 2410078G03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382018
Homologene: 11279
Tbc1d9
Name: TBC1 domain family, member 9
Synonyms: C76116, 4933431N12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71310
Homologene: 57079
Myf6
Name: myogenic factor 6
Synonyms: bHLHc4, herculin, MRF4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17878
VEGA: 10
HGNC: HGNC:7566
Homologene: 1850
Rflnb
Name: refilin B
Synonyms: RefilinB, 1500005K14Rik, cfm, Fam101b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76566
Homologene: 18809
Gm11360
Name: predicted gene 11360
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100041036
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: Cryabp1, alphaA-CRYBP1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
Zcchc9
Name: zinc finger, CCHC domain containing 9
Synonyms: 1810019C21Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69085
Homologene: 12999
Scamp1
Name: secretory carrier membrane protein 1
Synonyms: 4930505M11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107767
Homologene: 37975
Pbk
Name: PDZ binding kinase
Synonyms: D14Ertd732e, 2810434B10Rik, TOPK
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 52033
Homologene: 32415
Cacna1i
Name: calcium channel, voltage-dependent, alpha 1I subunit
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239556
HGNC: HGNC:1396
Homologene: 69331
Vmn2r93
Name: vomeronasal 2, receptor 93
Synonyms: EG627132
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627132
Homologene: 129750
Slc8a1
Name: solute carrier family 8 (sodium/calcium exchanger), member 1
Synonyms: Ncx1, D930008O12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20541
VEGA: 17
Homologene: 69090
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 66,413,163 bp
  • T to A, chromosome 1 at 85,270,052 bp
  • G to A, chromosome 1 at 92,029,984 bp
  • T to C, chromosome 1 at 151,448,380 bp
  • A to T, chromosome 1 at 188,964,846 bp
  • A to T, chromosome 2 at 26,949,340 bp
  • T to C, chromosome 2 at 111,059,416 bp
  • C to A, chromosome 2 at 117,294,820 bp
  • A to G, chromosome 2 at 162,948,828 bp
  • T to C, chromosome 3 at 119,720,641 bp
  • A to G, chromosome 3 at 152,428,403 bp
  • A to T, chromosome 4 at 112,711,556 bp
  • A to G, chromosome 4 at 118,476,280 bp
  • T to C, chromosome 4 at 123,475,248 bp
  • A to G, chromosome 5 at 29,598,938 bp
  • A to G, chromosome 5 at 66,974,622 bp
  • T to C, chromosome 6 at 84,063,331 bp
  • T to A, chromosome 6 at 92,890,167 bp
  • C to T, chromosome 6 at 140,524,903 bp
  • T to A, chromosome 7 at 19,294,471 bp
  • T to C, chromosome 7 at 27,233,481 bp
  • C to T, chromosome 7 at 28,911,570 bp
  • G to A, chromosome 7 at 44,623,127 bp
  • A to T, chromosome 7 at 79,677,410 bp
  • A to G, chromosome 8 at 13,013,060 bp
  • A to C, chromosome 8 at 71,634,658 bp
  • A to G, chromosome 8 at 80,503,081 bp
  • A to G, chromosome 8 at 83,234,243 bp
  • A to G, chromosome 9 at 45,867,498 bp
  • A to T, chromosome 9 at 113,860,141 bp
  • G to C, chromosome 9 at 121,472,907 bp
  • A to T, chromosome 10 at 107,493,479 bp
  • G to T, chromosome 10 at 115,423,474 bp
  • A to G, chromosome 11 at 55,162,640 bp
  • C to T, chromosome 11 at 69,914,781 bp
  • A to T, chromosome 11 at 76,022,161 bp
  • A to G, chromosome 12 at 91,505,283 bp
  • T to A, chromosome 12 at 100,616,083 bp
  • A to G, chromosome 12 at 103,059,518 bp
  • A to G, chromosome 12 at 108,463,527 bp
  • A to T, chromosome 13 at 14,637,743 bp
  • T to A, chromosome 13 at 27,956,231 bp
  • T to A, chromosome 13 at 42,158,656 bp
  • T to C, chromosome 13 at 91,797,249 bp
  • T to C, chromosome 13 at 92,473,996 bp
  • T to C, chromosome 13 at 94,204,150 bp
  • C to T, chromosome 13 at 112,886,862 bp
  • A to T, chromosome 14 at 30,075,010 bp
  • G to A, chromosome 14 at 33,162,751 bp
  • G to A, chromosome 14 at 65,815,226 bp
  • A to T, chromosome 14 at 110,749,932 bp
  • A to T, chromosome 15 at 80,381,172 bp
  • C to A, chromosome 15 at 99,212,287 bp
  • A to T, chromosome 16 at 55,915,561 bp
  • A to G, chromosome 16 at 90,447,312 bp
  • A to T, chromosome 16 at 90,866,417 bp
  • A to T, chromosome 17 at 18,326,410 bp
  • A to T, chromosome 17 at 30,594,271 bp
  • T to C, chromosome 17 at 51,804,336 bp
  • T to C, chromosome 17 at 57,075,465 bp
  • A to G, chromosome 17 at 74,225,458 bp
  • A to G, chromosome 17 at 81,437,759 bp
  • T to A, chromosome 18 at 68,339,566 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0067 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038358-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.