Strain Name:
C57BL/6J-MtgxR0079Btlr/Mmmh
Stock Number:
038366-MU
Citation ID:
RRID:MMRRC_038366-MU
Other Names:
R0079 (G1), C57BL/6J-MtgxR0079Btlr
Major Collection:

Gene Information

Mitf
Name: melanogenesis associated transcription factor
Synonyms: BCC2, mi, wh, bHLHe32, Gsfbcc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17342
HGNC: HGNC:7105
Homologene: 4892
Nsmf
Name: NMDA receptor synaptonuclear signaling and neuronal migration factor
Synonyms: Nelf, Jacob
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56876
Homologene: 10648
Ank2
Name: ankyrin 2, brain
Synonyms: Ank-2, ankyrin B, Gm4392, Ankyrin-2, Ankyrin-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Dhrs3
Name: dehydrogenase/reductase (SDR family) member 3
Synonyms: retSDR1, Rsdr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20148
Homologene: 20994
Cep55
Name: centrosomal protein 55
Synonyms: 2700032M20Rik, 1200008O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74107
VEGA: 19
HGNC: HGNC:1161
Homologene: 10019
Clasp1
Name: CLIP associating protein 1
Synonyms: CLASP1, B130045P17Rik, CLASP1alpha, mCLASP1, 1700030C23Rik, 5730583A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76707
Homologene: 41024
Ranbp17
Name: RAN binding protein 17
Synonyms: 4932704E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66011
Homologene: 36409
Tgds
Name: TDP-glucose 4,6-dehydratase
Synonyms: 2610025M23Rik, 2610017J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 76355
VEGA: 14
Homologene: 129708
Tm9sf4
Name: transmembrane 9 superfamily protein member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99237
Homologene: 21620
Denr
Name: density-regulated protein
Synonyms: 1500003K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68184
HGNC: HGNC:2769
Homologene: 6275
Zfp341
Name: zinc finger protein 341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228807
Homologene: 13127
Taf1d
Name: TATA-box binding protein associated factor, RNA polymerase I, D
Synonyms: 4930553M18Rik, Josd3, TAF(I)41, TAFI41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75316
VEGA: 9
Homologene: 11472
Eif4enif1
Name: eukaryotic translation initiation factor 4E nuclear import factor 1
Synonyms: 2610509L04Rik, A930019J01Rik, D11Ertd166e, Clast4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74203
Homologene: 10522
Xdh
Name: xanthine dehydrogenase
Synonyms: Xor, XO, Xox1, Xox-1, xanthine oxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19876
Homologene: 2206
Lyn
Name: LYN proto-oncogene, Src family tyrosine kinase
Synonyms: Yamaguchi sarcoma viral (v-yes-1) oncogene homolog, Hck-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17096
HGNC: HGNC:6735
Homologene: 55649
Strip2
Name: striatin interacting protein 2
Synonyms: D330017J20Rik, Fam40b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320609
Homologene: 66198
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: 2610100B16Rik, Ten-m3, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Cep152
Name: centrosomal protein 152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99100
Homologene: 37159
Zscan22
Name: zinc finger and SCAN domain containing 22
Synonyms: D530006B18Rik, Hkr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232878
HGNC: HGNC:4929
Homologene: 68122
Mctp2
Name: multiple C2 domains, transmembrane 2
Synonyms: LOC244049
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244049
Homologene: 69254
Kcnv1
Name: potassium channel, subfamily V, member 1
Synonyms: 2700023A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67498
VEGA: 15
Homologene: 22811
Spink5
Name: serine peptidase inhibitor, Kazal type 5
Synonyms: LEKT1, 2310065D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 72432
Homologene: 4987
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Trak2
Name: trafficking protein, kinesin binding 2
Synonyms: OIP98, 4733401O11Rik, Als2cr3, GRIF1, CALS-C, GRIF-1, 2900022D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70827
Homologene: 22861
Vmn1r28
Name: vomeronasal 1 receptor 28
Synonyms: V1rc25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171198
Homologene: 138094
Miox
Name: myo-inositol oxygenase
Synonyms: Aldrl6, RSOR, C85427, 0610009I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 56727
Homologene: 9732
Il12rb2
Name: interleukin 12 receptor, beta 2
Synonyms: Ifnm, IL-12RB2, A930027I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16162
HGNC: HGNC:5972
Homologene: 1197
Gckr
Name: glucokinase regulatory protein
Synonyms: GKRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231103
HGNC: HGNC:4196
Homologene: 1139
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Glt6d1
Name: glycosyltransferase 6 domain containing 1
Synonyms: 4933411C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71103
Homologene: 18826
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: AIB3, NRC, ASC-2, ASC2, PRIP, RAP250
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56406
Homologene: 137337
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78309
Homologene: 56696
Sntg1
Name: syntrophin, gamma 1
Synonyms: SYN4, G1SYN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71096
Homologene: 56834
Nlrp2
Name: NLR family, pyrin domain containing 2
Synonyms: Nalp2, E330007A02Rik, PYPAF2, Nbs1, Pan1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232827
Homologene: 56789
Wdr64
Name: WD repeat domain 64
Synonyms: 4930511H01Rik, 4930415O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75820
Homologene: 51634
Adamts3
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
Synonyms: 1100001H14Rik, 6330442E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: Myhs-f, Myhs-f2, MyHC-IId/x, IId, Myhsf2, IId/x, myosin heavy chain 2X, MYHC-IIX, A530084A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Nsun7
Name: NOL1/NOP2/Sun domain family, member 7
Synonyms: 4921525L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70918
Homologene: 11653
Gm9839
Name: predicted gene 9839
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 408192
Homologene: 130042
Ildr2
Name: immunoglobulin-like domain containing receptor 2
Synonyms: D1Ertd471e, Dbsm1, 3110063L10Rik, OTTMUSG00000021748, 2810478N18Rik, ENSMUSG00000040612
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100039795
Homologene: 52388
Phf19
Name: PHD finger protein 19
Synonyms: 3321402G02Rik, 3110009G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74016
Homologene: 12524
Cytip
Name: cytohesin 1 interacting protein
Synonyms: Pscdbp, Cbp, A130053M09Rik, Cybr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227929
HGNC: HGNC:9506
Homologene: 3167
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329421
Homologene: 51393
Olfr1168
Name: olfactory receptor 1168
Synonyms: GA_x6K02T2Q125-49669483-49670421, MOR174-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258524
Homologene: 128091
Gm5843
Name: predicted gene 5843
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 545507
Trnau1ap
Name: tRNA selenocysteine 1 associated protein 1
Synonyms: Trspap1, 1110007F05Rik, SECp43
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71787
Homologene: 49509
Chd5
Name: chromodomain helicase DNA binding protein 5
Synonyms: 4930532L22Rik, B230399N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269610
Homologene: 56712
Hpd
Name: 4-hydroxyphenylpyruvic acid dioxygenase
Synonyms: Hppd, Fla, Flp, Laf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15445
HGNC: HGNC:5147
Homologene: 1620
Vmn1r20
Name: vomeronasal 1 receptor 20
Synonyms: Gm5569
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434017
Homologene: 79462
Egr4
Name: early growth response 4
Synonyms: pAT133, NGF1-C, NGFI-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13656
HGNC: HGNC:3241
Homologene: 1485
Vmn1r170
Name: vomeronasal 1 receptor 170
Synonyms: Gm5999
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546944
Homologene: 128341
Olfr679
Name: olfactory receptor 679
Synonyms: GA_x6K02T2PBJ9-7714499-7715446, MOR40-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259046
Homologene: 81538
Olfr394
Name: olfactory receptor 394
Synonyms: GA_x6K02T2P1NL-4043306-4042374, MOR135-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259009
Homologene: 133669
2410004P03Rik
Name: RIKEN cDNA 2410004P03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73667
Homologene: 77698
Zfp641
Name: zinc finger protein 641
Synonyms: 9930016F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239652
VEGA: 15
Homologene: 17548
Olfr1564
Name: olfactory receptor 1564
Synonyms: Gm4461
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100043474
Homologene: 133726
Vars2
Name: valyl-tRNA synthetase 2, mitochondrial
Synonyms: 1190004I24Rik, Vars2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68915
Homologene: 57502
Mrpl21
Name: mitochondrial ribosomal protein L21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 353242
Homologene: 32936
Snx15
Name: sorting nexin 15
Synonyms: 1500032B08Rik, E130013C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69024
Homologene: 12294
Thoc2
Name: THO complex 2
Synonyms: LOC382210, D130005M13Rik, 6330441O12Rik, LOC386493
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 331401
Homologene: 69669
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 8,679,062 bp
  • A to G, chromosome 1 at 32,519,915 bp
  • A to T, chromosome 1 at 58,926,724 bp
  • T to C, chromosome 1 at 118,543,304 bp
  • A to T, chromosome 1 at 166,307,720 bp
  • T to C, chromosome 1 at 175,795,102 bp
  • T to C, chromosome 2 at 25,059,084 bp
  • C to A, chromosome 2 at 25,794,727 bp
  • T to C, chromosome 2 at 34,895,954 bp
  • T to A, chromosome 2 at 58,159,994 bp
  • A to G, chromosome 2 at 70,095,158 bp
  • A to T, chromosome 2 at 88,185,354 bp
  • T to A, chromosome 2 at 125,618,453 bp
  • T to A, chromosome 2 at 153,191,145 bp
  • T to A, chromosome 2 at 154,624,994 bp
  • TGC to TGCGC, chromosome 2 at 155,408,291 bp
  • G to T, chromosome 3 at 14,724,128 bp
  • G to T, chromosome 3 at 126,934,615 bp
  • A to G, chromosome 4 at 3,746,768 bp
  • A to G, chromosome 4 at 132,314,345 bp
  • A to T, chromosome 4 at 144,920,048 bp
  • A to G, chromosome 4 at 152,385,749 bp
  • A to G, chromosome 5 at 31,306,539 bp
  • C to T, chromosome 5 at 66,295,513 bp
  • G to C, chromosome 5 at 89,693,053 bp
  • T to C, chromosome 5 at 123,181,481 bp
  • T to G, chromosome 5 at 123,924,845 bp
  • T to C, chromosome 6 at 29,920,533 bp
  • A to T, chromosome 6 at 57,431,792 bp
  • G to A, chromosome 6 at 58,265,717 bp
  • A to T, chromosome 6 at 67,361,905 bp
  • A to T, chromosome 6 at 85,512,769 bp
  • A to C, chromosome 6 at 97,996,440 bp
  • T to A, chromosome 7 at 5,327,730 bp
  • T to C, chromosome 7 at 12,904,087 bp
  • T to A, chromosome 7 at 23,606,310 bp
  • T to A, chromosome 7 at 72,214,116 bp
  • T to C, chromosome 7 at 105,085,928 bp
  • A to G, chromosome 8 at 48,343,345 bp
  • C to T, chromosome 9 at 15,309,944 bp
  • C to T, chromosome 11 at 3,242,676 bp
  • G to A, chromosome 11 at 9,293,493 bp
  • A to C, chromosome 11 at 33,500,682 bp
  • T to A, chromosome 11 at 67,213,411 bp
  • T to G, chromosome 11 at 73,887,737 bp
  • T to A, chromosome 12 at 17,007,182 bp
  • G to A, chromosome 13 at 74,283,024 bp
  • A to T, chromosome 14 at 118,116,235 bp
  • T to C, chromosome 15 at 45,113,333 bp
  • C to T, chromosome 15 at 89,336,274 bp
  • T to C, chromosome 15 at 98,289,089 bp
  • A to G, chromosome 16 at 72,933,342 bp
  • G to A, chromosome 17 at 33,216,105 bp
  • A to T, chromosome 17 at 35,659,156 bp
  • C to A, chromosome 17 at 46,537,663 bp
  • G to A, chromosome 17 at 73,891,218 bp
  • G to T, chromosome 18 at 43,977,764 bp
  • T to C, chromosome 19 at 3,284,807 bp
  • A to G, chromosome 19 at 6,123,913 bp
  • C to T, chromosome 19 at 38,060,321 bp
  • G to T, chromosome X at 41,864,108 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0079 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038366-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.