Strain Name:
C57BL/6J-MtgxR0121Btlr/Mmmh
Stock Number:
038406-MU
Citation ID:
RRID:MMRRC_038406-MU
Other Names:
R0121 (G1), C57BL/6J-MtgxR0121Btlr
Major Collection:

Gene Information

Col1a1
Name: collagen, type I, alpha 1
Synonyms: Mov-13, Cola1, Col1a-1, Cola-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12842
HGNC: HGNC:2197
Homologene: 73874
Sbf2
Name: SET binding factor 2
Synonyms: B430219L04Rik, SBF2, 4833411B01Rik, mMTMH1, Mtmr13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Ubn2
Name: ubinuclein 2
Synonyms: D130059P03Rik, 6030408G03Rik, 2900060J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320538
Homologene: 45564
Gabra6
Name: gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
Synonyms: GABA-ARalpha6, Gabra-6, alpha6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14399
HGNC: HGNC:4080
Homologene: 20220
Abca12
Name: ATP-binding cassette, sub-family A (ABC1), member 12
Synonyms: 4832428G11Rik, 4833417A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74591
Homologene: 45441
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: 2810017C20Rik, E130319N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 215351
Homologene: 9196
Cct6a
Name: chaperonin containing Tcp1, subunit 6a (zeta)
Synonyms: Cct6, chaperonin containing TCP-1, Cctz-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12466
HGNC: HGNC:1620
Homologene: 1336
Tdrd3
Name: tudor domain containing 3
Synonyms: 4732418C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219249
Homologene: 12771
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 21819
Homologene: 2430
Arfip2
Name: ADP-ribosylation factor interacting protein 2
Synonyms: 2310002N04Rik, Arfaptin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76932
Homologene: 8234
Ccnh
Name: cyclin H
Synonyms: 6330408H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66671
HGNC: HGNC:1594
Homologene: 946
L3mbtl3
Name: L3MBTL3 histone methyl-lysine binding protein
Synonyms: MBT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237339
Homologene: 18226
Foxi2
Name: forkhead box I2
Synonyms: B130055A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 270004
Homologene: 18838
Tmtc3
Name: transmembrane and tetratricopeptide repeat containing 3
Synonyms: B130008E12Rik, mSmile, 9130014E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237500
Homologene: 27616
Cul7
Name: cullin 7
Synonyms: p185, p193, 2510004L20Rik, C230011P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66515
Homologene: 56683
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: Gpr125, 3830613O22Rik, Tem5-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70693
Homologene: 19235
Grhl3
Name: grainyhead like transcription factor 3
Synonyms: ct, Som, Get1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230824
Homologene: 18864
Anxa7
Name: annexin A7
Synonyms: synexin, Anx7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 11750
VEGA: 14
HGNC: HGNC:545
Homologene: 36149
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: 4432416O06Rik, DHC2, b2b414Clo, Dnchc2, m407Asp, m152Asp, D030010H02Rik, D330044F14Rik, DHC1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Sptbn2
Name: spectrin beta, non-erythrocytic 2
Synonyms: Spnb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20743
VEGA: 19
Homologene: 48482
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, Odz3, 2610100B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 23965
Homologene: 22673
Asph
Name: aspartate-beta-hydroxylase
Synonyms: Junctin, cI-37, junctate, calsequestrin-binding protein, aspartyl beta-hydroxylase, 3110001L23Rik, jumbug, 2310005F16Rik, BAH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 65973
HGNC: HGNC:757
Homologene: 20910
Nolc1
Name: nucleolar and coiled-body phosphoprotein 1
Synonyms: NOPP140, 3230402K17Rik, P130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 70769
VEGA: 19
Ubac1
Name: ubiquitin associated domain containing 1
Synonyms: 1110033G07Rik, Ubadc1, Kpc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98766
Homologene: 9409
Kel
Name: Kell blood group
Synonyms: CD238
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 23925
HGNC: HGNC:6308
Homologene: 362
Atp4a
Name: ATPase, H+/K+ exchanging, gastric, alpha polypeptide
Synonyms: H+K+-transporting alpha 1, H+/K+-ATPase alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11944
HGNC: HGNC:819
Homologene: 68081
Optn
Name: optineurin
Synonyms: 4930441O07Rik, TFIIIA-INTP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71648
Homologene: 11085
Clec4b2
Name: C-type lectin domain family 4, member b2
Synonyms: mDCAR1, F830043G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 381809
Homologene: 128249
Arhgap20
Name: Rho GTPase activating protein 20
Synonyms: 6530403F17Rik, A530023E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244867
Homologene: 18938
Ephb2
Name: Eph receptor B2
Synonyms: Hek5, eteck, Prkm5, Nuk, Tyro5, Drt, Erk, Cek5, Qek5, Sek3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13844
HGNC: HGNC:3393
Homologene: 37925
Gm4847
Name: predicted gene 4847
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226604
Homologene: 101040
Cyp2b13
Name: cytochrome P450, family 2, subfamily b, polypeptide 13
Synonyms: phenobarbital inducible, type c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13089
Homologene: 74933
Csf3r
Name: colony stimulating factor 3 receptor (granulocyte)
Synonyms: Cd114, Csfgr, G-CSFR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12986
HGNC: HGNC:2439
Homologene: 601
Serpinb1a
Name: serine (or cysteine) peptidase inhibitor, clade B, member 1a
Synonyms: EIA, MNEI, M/NEI, LEI, ovalbumin, 1190005M04Rik, ELANH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66222
HGNC: HGNC:3311
Homologene: 133768
Atp2a1
Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Synonyms: SERCA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11937
HGNC: HGNC:811
Homologene: 7635
Mamdc2
Name: MAM domain containing 2
Synonyms: mamcan, 1200015L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 71738
VEGA: 19
Homologene: 17722
Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms: Atpa-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98660
HGNC: HGNC:800
Homologene: 47947
Gtdc1
Name: glycosyltransferase-like domain containing 1
Synonyms: E330008O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227835
Homologene: 32590
Olfr1085
Name: olfactory receptor 1085
Synonyms: MOR191-1, GA_x6K02T2Q125-48147264-48146323
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258583
Olfr1153
Name: olfactory receptor 1153
Synonyms: MOR177-7, GA_x6K02T2Q125-49395950-49396882
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258633
Homologene: 27230
Olfr1277
Name: olfactory receptor 1277
Synonyms: GA_x6K02T2Q125-72321818-72320907, MOR248-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258391
Homologene: 105176
Slc2a9
Name: solute carrier family 2 (facilitated glucose transporter), member 9
Synonyms: Glut9, SLC2A9B, SLC2a9A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 117591
Homologene: 69290
Tecpr1
Name: tectonin beta-propeller repeat containing 1
Synonyms: 2210010N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70381
Homologene: 9120
B4galnt3
Name: beta-1,4-N-acetyl-galactosaminyl transferase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330406
Homologene: 18328
Olfr937
Name: olfactory receptor 937
Synonyms: GA_x6K02T2PVTD-32756567-32755632, MOR171-24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258431
VEGA: 9
Homologene: 27167
Tcf21
Name: transcription factor 21
Synonyms: podocyte-expressed 1, Pod-1, epicardin, capsulin, bHLHa23, epc, Pod1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 21412
VEGA: 10
Homologene: 2414
Pbld1
Name: phenazine biosynthesis-like protein domain containing 1
Synonyms: Pbld, 0610038K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 68371
VEGA: 10
Homologene: 41470
Prl8a9
Name: prolactin family8, subfamily a, member 9
Synonyms: PLP-Cbeta, 1600019F10Rik, Prlpc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 67310
Homologene: 11344
Edn1
Name: endothelin 1
Synonyms: ET-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13614
VEGA: 13
HGNC: HGNC:3176
Homologene: 1476
Zfp944
Name: zinc finger protein 944
Synonyms: 6330416L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 319615
VEGA: 17
Homologene: 133237
Nudt12
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 12
Synonyms: 0610016O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67993
Homologene: 44188
Ccdc178
Name: coiled coil domain containing 178
Synonyms: 4921528I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70950
VEGA: 18
Homologene: 12373
Fam111a
Name: family with sequence similarity 111, member A
Synonyms: 4632417K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107373
Homologene: 49696
Twnk
Name: twinkle mtDNA helicase
Synonyms: twinkle, D19Ertd626e, Peo1, Twinl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226153
VEGA: 19
HGNC: HGNC:1160
Homologene: 11052
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 71,259,786 bp
  • T to C, chromosome 1 at 166,642,288 bp
  • T to A, chromosome 1 at 172,289,342 bp
  • C to T, chromosome 2 at 5,024,115 bp
  • A to G, chromosome 2 at 26,008,859 bp
  • T to C, chromosome 2 at 44,565,538 bp
  • A to G, chromosome 2 at 86,657,819 bp
  • A to G, chromosome 2 at 87,897,090 bp
  • A to T, chromosome 2 at 111,270,314 bp
  • T to C, chromosome 4 at 9,635,918 bp
  • A to G, chromosome 4 at 126,029,849 bp
  • A to G, chromosome 4 at 135,552,549 bp
  • A to G, chromosome 4 at 136,771,057 bp
  • T to C, chromosome 5 at 38,398,743 bp
  • T to C, chromosome 5 at 50,025,786 bp
  • T to A, chromosome 5 at 129,791,570 bp
  • C to T, chromosome 5 at 144,210,199 bp
  • T to C, chromosome 6 at 38,452,858 bp
  • A to C, chromosome 6 at 41,702,064 bp
  • C to T, chromosome 6 at 120,215,038 bp
  • A to G, chromosome 6 at 123,204,172 bp
  • G to A, chromosome 7 at 26,086,585 bp
  • C to G, chromosome 7 at 30,720,101 bp
  • A to G, chromosome 7 at 105,636,371 bp
  • A to G, chromosome 7 at 110,489,219 bp
  • A to G, chromosome 7 at 126,457,944 bp
  • C to A, chromosome 7 at 135,411,911 bp
  • G to A, chromosome 8 at 48,342,659 bp
  • A to T, chromosome 9 at 7,001,327 bp
  • T to A, chromosome 9 at 39,059,760 bp
  • A to G, chromosome 9 at 51,838,951 bp
  • A to G, chromosome 9 at 80,116,670 bp
  • T to C, chromosome 10 at 22,819,807 bp
  • C to T, chromosome 10 at 26,313,870 bp
  • C to T, chromosome 10 at 63,071,503 bp
  • A to G, chromosome 10 at 100,458,908 bp
  • A to G, chromosome 11 at 42,314,971 bp
  • A to G, chromosome 11 at 83,321,967 bp
  • A to G, chromosome 11 at 94,938,069 bp
  • T to G, chromosome 13 at 27,560,606 bp
  • T to A, chromosome 13 at 32,848,771 bp
  • A to G, chromosome 13 at 42,305,265 bp
  • T to A, chromosome 13 at 85,206,193 bp
  • A to T, chromosome 14 at 20,460,159 bp
  • A to T, chromosome 14 at 87,539,479 bp
  • A to T, chromosome 15 at 66,740,781 bp
  • T to A, chromosome 17 at 22,339,268 bp
  • C to T, chromosome 17 at 46,663,373 bp
  • A to T, chromosome 17 at 59,007,639 bp
  • T to A, chromosome 17 at 67,798,513 bp
  • C to A, chromosome 18 at 21,845,024 bp
  • T to C, chromosome 19 at 4,745,293 bp
  • T to A, chromosome 19 at 12,584,080 bp
  • T to A, chromosome 19 at 23,310,859 bp
  • T to C, chromosome 19 at 45,009,265 bp
  • G to A, chromosome 19 at 46,081,378 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0121 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038406-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.