Strain Name:
C57BL/6J-MtgxR0152Btlr/Mmmh
Stock Number:
038435-MU
Citation ID:
RRID:MMRRC_038435-MU
Other Names:
R0152 (G1), C57BL/6J-MtgxR0152Btlr
Major Collection:

Gene Information

Cd4
Name: CD4 antigen
Synonyms: L3T4, Ly-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12504
HGNC: HGNC:1678
Homologene: 513
Pdpk1
Name: 3-phosphoinositide dependent protein kinase 1
Synonyms: Pkb kinase, Pdk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18607
HGNC: HGNC:8816
Homologene: 37643
Ldb2
Name: LIM domain binding 2
Synonyms: Ldb3, CLIM-1b, CLP-36, CLIM-1a, CLIM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16826
HGNC: HGNC:6533
Homologene: 989
Dst
Name: dystonin
Synonyms: Macf2, Bpag, athetoid, bullous pemphigoid antigen 1, nmf339, 2310001O04Rik, nmf203, A830042E19Rik, ah, Bpag1, BPAG1, BPAG1-n, bullous pemphigoid antigen 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Ercc6
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: CS group B correcting gene, CSB, C130058G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 319955
VEGA: 14
HGNC: HGNC:3438
Homologene: 133552
Eif3e
Name: eukaryotic translation initiation factor 3, subunit E
Synonyms: eIF3-p46, Eif3s6, Int6, eIF3-p48, 48kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16341
VEGA: 15
HGNC: HGNC:3277
Homologene: 1205
Arfip2
Name: ADP-ribosylation factor interacting protein 2
Synonyms: 2310002N04Rik, Arfaptin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76932
Homologene: 8234
Snapc1
Name: small nuclear RNA activating complex, polypeptide 1
Synonyms: 9630050P21Rik, 2700033G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75627
VEGA: 12
Homologene: 2317
Rbm26
Name: RNA binding motif protein 26
Synonyms: Pro1777, C230097K14Rik, 1700009P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 74213
Homologene: 41468
Aqr
Name: aquarius
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11834
Homologene: 7629
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: NMHC II-C, 2400004E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71960
Homologene: 23480
Pgr
Name: progesterone receptor
Synonyms: ENSMUSG00000074510, PR-A, 9930019P03Rik, NR3C3, PR-B, PR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18667
HGNC: HGNC:8910
Homologene: 713
Pum2
Name: pumilio RNA-binding family member 2
Synonyms: Pumm2, 5730503J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 80913
Homologene: 69183
Zfp68
Name: zinc finger protein 68
Synonyms: Zfp68, KRAZ2, Zfp70, KRAB3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 24135
Homologene: 56605
Recql5
Name: RecQ protein-like 5
Synonyms: Recq5b, Recql5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 170472
HGNC: HGNC:9950
Homologene: 31232
U2af1
Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
Synonyms: 35kDa, 2010107D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 108121
VEGA: 17
Homologene: 14345
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4921518A06Rik, 4933421G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Arhgap44
Name: Rho GTPase activating protein 44
Synonyms: AU040829
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216831
Homologene: 65284
Wdcp
Name: WD repeat and coiled coil containing
Synonyms: BC068281
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238037
VEGA: 12
Homologene: 49822
Fam169b
Name: family with sequence similarity 169, member B
Synonyms: EG434197
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434197
Homologene: 79038
Slc9a2
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 2
Synonyms: NHE2, 4932415O19Rik, 2210416H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226999
Homologene: 20661
Itga2
Name: integrin alpha 2
Synonyms: CD49B, DX5, VLA-2 receptor, alpha 2 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16398
VEGA: 13
HGNC: HGNC:6137
Homologene: 1662
Pram1
Name: PML-RAR alpha-regulated adaptor molecule 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 378460
Homologene: 12963
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Tub
Name: tubby bipartite transcription factor
Synonyms: rd5, tub
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22141
Homologene: 31147
Hmcn1
Name: hemicentin 1
Synonyms: EG545370, LOC240793
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Mfsd12
Name: major facilitator superfamily domain containing 12
Synonyms: F630110N24Rik, gr, Wdt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73822
Homologene: 45488
Exph5
Name: exophilin 5
Synonyms: AC079869.22gm5, slac2-b, Slac2b, B130009M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320051
Homologene: 9007
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Vmn2r1
Name: vomeronasal 2, receptor 1
Synonyms: V2r83, EG56544
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56544
Homologene: 84832
Slco1a1
Name: solute carrier organic anion transporter family, member 1a1
Synonyms: Oatp1a1, Slc21a1, Oatp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 28248
Homologene: 137261
Olfr293
Name: olfactory receptor 293
Synonyms: GA_x6K02T2NHDJ-9457744-9456734, MOR221-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257906
Homologene: 79385
Zbtb38
Name: zinc finger and BTB domain containing 38
Synonyms: Zenon homolog, A930014K01Rik, CIBZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245007
Homologene: 19529
Slc17a3
Name: solute carrier family 17 (sodium phosphate), member 3
Synonyms: Npt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105355
Homologene: 21319
Olfr1331
Name: olfactory receptor 1331
Synonyms: GA_x6K02T2QD9B-18670866-18669913, MOR259-3P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258159
Homologene: 134082
Vars2
Name: valyl-tRNA synthetase 2, mitochondrial
Synonyms: 1190004I24Rik, Vars2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68915
Homologene: 57502
Rims4
Name: regulating synaptic membrane exocytosis 4
Synonyms: Rim4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241770
Homologene: 18123
Olfr948
Name: olfactory receptor 948
Synonyms: MOR171-51, MOR171-45, GA_x6K02T2PVTD-33016899-33015934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 257912
VEGA: 9
Homologene: 79377
Mgarp
Name: mitochondria localized glutamic acid rich protein
Synonyms: 4930583H14Rik, Osap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67749
Homologene: 49858
Olfr372
Name: olfactory receptor 372
Synonyms: MOR282-1, GA_x6K02T2NUPS-191522-192466
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 404315
Homologene: 17287
Arhgef26
Name: Rho guanine nucleotide exchange factor (GEF) 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 622434
Homologene: 9204
Usp3
Name: ubiquitin specific peptidase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235441
Homologene: 4766
Pdhx
Name: pyruvate dehydrogenase complex, component X
Synonyms: Pdx1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27402
Homologene: 55757
Aass
Name: aminoadipate-semialdehyde synthase
Synonyms: LOR/SDH, Lorsdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 30956
Homologene: 4212
Clip3
Name: CAP-GLY domain containing linker protein 3
Synonyms: 1500005P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76686
Homologene: 9176
Eri2
Name: exoribonuclease 2
Synonyms: 4933424N09Rik, Exod1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71151
Homologene: 12383
Kbtbd11
Name: kelch repeat and BTB (POZ) domain containing 11
Synonyms: 2900016B01Rik, 4930465M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74901
Homologene: 28701
Car5a
Name: carbonic anhydrase 5a, mitochondrial
Synonyms: Car5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12352
HGNC: HGNC:1377
Homologene: 68200
Zmynd10
Name: zinc finger, MYND domain containing 10
Synonyms: Blu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114602
Homologene: 9293
Slc26a4
Name: solute carrier family 26, member 4
Synonyms: pendrin, Pds
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 23985
VEGA: 12
HGNC: HGNC:8818
Homologene: 20132
Cgrrf1
Name: cell growth regulator with ring finger domain 1
Synonyms: 1810009H17Rik, 1110038G02Rik, CGR19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68755
Homologene: 4789
H2-M2
Name: histocompatibility 2, M region locus 2
Synonyms: H-2M2, Thy19.4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14990
Homologene: 133732
Olfr1448
Name: olfactory receptor 1448
Synonyms: GA_x6K02T2RE5P-3249780-3248836, MOR202-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258696
Homologene: 64904
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 34,189,119 bp
  • A to G, chromosome 1 at 40,742,804 bp
  • A to T, chromosome 1 at 150,663,879 bp
  • A to G, chromosome 2 at 103,028,280 bp
  • T to A, chromosome 2 at 114,159,010 bp
  • C to T, chromosome 2 at 163,863,929 bp
  • T to C, chromosome 3 at 51,388,963 bp
  • T to C, chromosome 3 at 62,423,544 bp
  • T to C, chromosome 3 at 64,081,819 bp
  • T to A, chromosome 4 at 118,868,886 bp
  • T to C, chromosome 5 at 44,541,799 bp
  • T to C, chromosome 5 at 138,606,613 bp
  • T to C, chromosome 6 at 23,074,689 bp
  • G to A, chromosome 6 at 124,867,746 bp
  • A to G, chromosome 6 at 141,911,942 bp
  • G to A, chromosome 7 at 30,303,432 bp
  • A to T, chromosome 7 at 44,623,181 bp
  • A to G, chromosome 7 at 68,321,919 bp
  • A to T, chromosome 7 at 86,664,511 bp
  • G to A, chromosome 7 at 105,637,223 bp
  • A to T, chromosome 7 at 109,020,927 bp
  • A to G, chromosome 7 at 119,790,383 bp
  • T to C, chromosome 8 at 15,027,428 bp
  • C to T, chromosome 8 at 72,058,400 bp
  • T to A, chromosome 8 at 121,916,446 bp
  • A to T, chromosome 9 at 8,965,022 bp
  • A to G, chromosome 9 at 39,319,461 bp
  • T to A, chromosome 9 at 53,353,204 bp
  • T to C, chromosome 9 at 66,540,150 bp
  • T to C, chromosome 9 at 96,686,280 bp
  • A to G, chromosome 9 at 107,550,945 bp
  • G to T, chromosome 10 at 81,357,799 bp
  • T to A, chromosome 11 at 9,581,724 bp
  • T to C, chromosome 11 at 59,052,576 bp
  • G to T, chromosome 11 at 65,011,919 bp
  • A to G, chromosome 11 at 115,894,673 bp
  • A to G, chromosome 12 at 4,851,583 bp
  • T to A, chromosome 12 at 8,728,754 bp
  • T to C, chromosome 12 at 31,529,498 bp
  • C to T, chromosome 12 at 73,975,032 bp
  • C to T, chromosome 13 at 23,855,858 bp
  • C to T, chromosome 13 at 114,866,314 bp
  • C to G, chromosome 14 at 32,546,905 bp
  • G to A, chromosome 14 at 46,853,913 bp
  • G to A, chromosome 14 at 105,176,769 bp
  • T to C, chromosome 15 at 8,319,443 bp
  • G to A, chromosome 15 at 43,252,236 bp
  • C to T, chromosome 17 at 24,106,946 bp
  • G to A, chromosome 17 at 31,655,069 bp
  • T to C, chromosome 17 at 33,642,119 bp
  • A to G, chromosome 17 at 35,660,027 bp
  • A to G, chromosome 17 at 37,483,433 bp
  • A to G, chromosome 19 at 12,920,108 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0152 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038435-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.