Strain Name:
C57BL/6J-MtgxR0166Btlr/Mmmh
Stock Number:
038442-MU
Citation ID:
RRID:MMRRC_038442-MU
Other Names:
R0166 (G1), C57BL/6J-MtgxR0166Btlr
Major Collection:

Strain Information

Drd1
Name: dopamine receptor D1
Synonyms: D1 receptor, Gpcr15, Drd-1, C030036C15Rik, Drd1a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13488
VEGA: 13
HGNC: HGNC:3020
Homologene: 30992
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Tet1
Name: tet methylcytosine dioxygenase 1
Synonyms: 2510010B09Rik, D10Ertd17e, Cxxc6, BB001228
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52463
Homologene: 12735
Cnot7
Name: CCR4-NOT transcription complex, subunit 7
Synonyms: Caf1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18983
Homologene: 49011
Llgl2
Name: LLGL2 scribble cell polarity complex component
Synonyms: 9130006H11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217325
HGNC: HGNC:6629
Homologene: 3323
Gpr55
Name: G protein-coupled receptor 55
Synonyms: LOC227326, CTFL
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227326
HGNC: HGNC:4511
Homologene: 36184
Carmil1
Name: capping protein regulator and myosin 1 linker 1
Synonyms: 1110037D04Rik, Lrrc16, Carmil, Lrrc16a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68732
Homologene: 9757
Atp2a2
Name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Synonyms: sarco/endoplasmic reticulum Ca2+-ATPase 2, SERCA2, 9530097L16Rik, D5Wsu150e, SERCA2B, Serca2a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11938
HGNC: HGNC:812
Homologene: 80167
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: 4930528H02Rik, Zfp294, Listerin, Rnf160
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Proser1
Name: proline and serine rich 1
Synonyms: 2810046L04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 212127
Homologene: 13463
Flnb
Name: filamin, beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Plxna1
Name: plexin A1
Synonyms: NOV, Plxn1, 2600013D04Rik, PlexA1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18844
HGNC: HGNC:9099
Homologene: 56426
Pkn2
Name: protein kinase N2
Synonyms: PRK2, 6030436C20Rik, Stk7, Prkcl2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109333
HGNC: HGNC:9406
Homologene: 2054
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212285
Homologene: 9064
Slc38a2
Name: solute carrier family 38, member 2
Synonyms: 5033402L14Rik, SNAT2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67760
VEGA: 15
Homologene: 23132
Dcaf4
Name: DDB1 and CUL4 associated factor 4
Synonyms: 1110018E21Rik, Wdr21
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73828
VEGA: 12
Homologene: 9210
Ttk
Name: Ttk protein kinase
Synonyms: Esk1, Mps1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22137
Homologene: 2489
Fubp1
Name: far upstream element (FUSE) binding protein 1
Synonyms: FBP, Fubp, Fubp4, 9530027K12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 51886
HGNC: HGNC:4004
Homologene: 48253
Slc49a4
Name: solute carrier family 49 member 4
Synonyms: RCC4, Dirc2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224132
Homologene: 13137
Pus10
Name: pseudouridylate synthase 10
Synonyms: 2810013G11Rik, 4933435A13Rik, Ccdc139
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74467
Homologene: 12566
Efna1
Name: ephrin A1
Synonyms: B61, Epl1, EFL-1, LERK-1, Lerk1, Eplg1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13636
HGNC: HGNC:3221
Homologene: 3262
Tnc
Name: tenascin C
Synonyms: Hxb, TN-C, TN, C130033P17Rik, tenascin-C, cytotactin, hexabrachion
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Kif22
Name: kinesin family member 22
Synonyms: Kif22a, Kid
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 110033
HGNC: HGNC:6391
Homologene: 32011
Azi2
Name: 5-azacytidine induced gene 2
Synonyms: AZ2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 27215
Homologene: 8443
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171395
Homologene: 51376
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Cyp7b1
Name: cytochrome P450, family 7, subfamily b, polypeptide 1
Synonyms: hct-1, D3Ertd552e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13123
HGNC: HGNC:2652
Homologene: 3544
Akap6
Name: A kinase anchor protein 6
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Ttn
Name: titin
Synonyms: connectin, L56, 1100001C23Rik, mdm, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Vmn1r28
Name: vomeronasal 1 receptor 28
Synonyms: V1rc25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171198
Homologene: 138094
Miox
Name: myo-inositol oxygenase
Synonyms: RSOR, 0610009I10Rik, C85427, Aldrl6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 56727
Homologene: 9732
Prdm1
Name: PR domain containing 1, with ZNF domain
Synonyms: PRDI-BF1, Blimp1, Blimp-1, b2b1765Clo
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12142
HGNC: HGNC:9346
Homologene: 925
Fsd1l
Name: fibronectin type III and SPRY domain containing 1-like
Synonyms: A230072O16Rik, Csdufd1, Ccdc10, Fsd1nl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 319636
Homologene: 45825
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: PRIP, ASC2, RAP250, AIB3, NRC, ASC-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56406
Homologene: 137337
Gbp5
Name: guanylate binding protein 5
Synonyms: 5330409J06Rik, Gbp5a
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229898
Homologene: 14183
Sctr
Name: secretin receptor
Synonyms: 6530402O03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319229
Homologene: 68290
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Macc1
Name: metastasis associated in colon cancer 1
Synonyms: 4732474O15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238455
Homologene: 18813
Adamts7
Name: ADAM metallopeptidase with thrombospondin type 1 motif 7
Synonyms: ADAM-TS7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 108153
HGNC: HGNC:223
Homologene: 22803
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Unc79
Name: unc-79 homolog
Synonyms: 9030205A07Rik, Mlca3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217843
Homologene: 41397
Spic
Name: Spi-C transcription factor (Spi-1/PU.1 related)
Synonyms: Spi-C, Prf, C76795
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20728
Homologene: 7953
Abcb1b
Name: ATP-binding cassette, sub-family B member 1B
Synonyms: Mdr1, Mdr1b, mdr, Pgy1, Pgy-1, Abcb1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18669
HGNC: HGNC:40
Homologene: 69084
Slc5a3
Name: solute carrier family 5 (inositol transporters), member 3
Synonyms: Smit1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 53881
Homologene: 31412
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Lyplal1
Name: lysophospholipase-like 1
Synonyms: Q96AVO
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226791
Homologene: 13683
Mdm1
Name: MDM1 nuclear protein
Synonyms: Mdm-1, transformed mouse 3T3 cell double minute 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17245
VEGA: 10
Homologene: 9692
Atp6v0d2
Name: ATPase, H+ transporting, lysosomal V0 subunit D2
Synonyms: 1620401A02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242341
Homologene: 72090
Pramel22
Name: PRAME like 22
Synonyms: Gm13088
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 277668
Homologene: 129883
Ttc28
Name: tetratricopeptide repeat domain 28
Synonyms: 2310015L07Rik, TPRBK
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 209683
Homologene: 41023
AC163025.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Cntnap5b
Name: contactin associated protein-like 5B
Synonyms: Caspr5-2, C230078M14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241175
Homologene: 104295
Cst7
Name: cystatin F (leukocystatin)
Synonyms: cystatin-like metastasis-associated protein, CMAP, Leukocystatin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13011
HGNC: HGNC:2479
Homologene: 37832
Impa1
Name: inositol (myo)-1(or 4)-monophosphatase 1
Synonyms: lithium-sensitive myo-inositol monophosphatase A1, 2610002K09Rik, 2900059K10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 55980
HGNC: HGNC:6050
Homologene: 4043
Nr0b2
Name: nuclear receptor subfamily 0, group B, member 2
Synonyms: small heterodimer partner, SHP-1, SHP
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 23957
HGNC: HGNC:7961
Homologene: 8030
Zfp467
Name: zinc finger protein 467
Synonyms: MNCb-3350, EZI, 1190001I08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68910
Homologene: 10758
Spib
Name: Spi-B transcription factor (Spi-1/PU.1 related)
Synonyms: Spi-B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 272382
Homologene: 79220
Tph1
Name: tryptophan hydroxylase 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21990
Homologene: 121565
Mrpl23
Name: mitochondrial ribosomal protein L23
Synonyms: L23mrp, Rpl23l
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19935
Homologene: 7922
Ddx28
Name: DEAD box helicase 28
Synonyms: Mddx28, 2410004K13Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71986
Homologene: 10164
Or8b53
Name: olfactory receptor family 8 subfamily B member 53
Synonyms: GA_x6K02T2PVTD-32458442-32459374, MOR165-6, Olfr920
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258783
VEGA: 9
Rpl27
Name: ribosomal protein L27
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19942
Homologene: 105144
Akr1c21
Name: aldo-keto reductase family 1, member C21
Synonyms: 9430025F20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 77337
Homologene: 134114
Ildr1
Name: immunoglobulin-like domain containing receptor 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106347
Homologene: 15892
Pcdhb14
Name: protocadherin beta 14
Synonyms: Pcdhb17, PcdhbN, 2210006M07Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93885
Homologene: 70876
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 21,272,734 bp
  • A to G, chromosome 1 at 85,941,136 bp
  • A to G, chromosome 1 at 100,274,361 bp
  • A to T, chromosome 1 at 120,055,394 bp
  • A to T, chromosome 1 at 186,088,746 bp
  • T to C, chromosome 2 at 76,867,492 bp
  • T to C, chromosome 2 at 150,575,727 bp
  • TGC to TGCGC, chromosome 2 at 155,408,291 bp
  • C to T, chromosome 3 at 10,328,960 bp
  • T to A, chromosome 3 at 18,097,366 bp
  • C to A, chromosome 3 at 53,480,617 bp
  • A to T, chromosome 3 at 89,272,830 bp
  • T to A, chromosome 3 at 142,506,919 bp
  • T to A, chromosome 3 at 142,830,625 bp
  • T to A, chromosome 3 at 152,220,204 bp
  • G to A, chromosome 4 at 19,910,768 bp
  • A to G, chromosome 4 at 53,647,664 bp
  • T to C, chromosome 4 at 63,962,162 bp
  • A to G, chromosome 4 at 133,553,738 bp
  • T to A, chromosome 4 at 143,654,511 bp
  • T to C, chromosome 5 at 8,853,468 bp
  • A to C, chromosome 5 at 62,676,018 bp
  • T to C, chromosome 5 at 111,225,634 bp
  • T to C, chromosome 5 at 122,466,838 bp
  • T to C, chromosome 6 at 48,438,681 bp
  • G to A, chromosome 6 at 58,265,717 bp
  • A to G, chromosome 6 at 89,333,019 bp
  • G to T, chromosome 7 at 44,529,900 bp
  • G to A, chromosome 7 at 46,304,231 bp
  • A to G, chromosome 7 at 46,647,596 bp
  • G to A, chromosome 7 at 127,034,036 bp
  • C to T, chromosome 7 at 142,535,114 bp
  • A to G, chromosome 8 at 16,233,022 bp
  • A to T, chromosome 8 at 40,507,453 bp
  • G to A, chromosome 8 at 106,010,289 bp
  • T to A, chromosome 9 at 38,756,188 bp
  • A to G, chromosome 9 at 83,862,330 bp
  • A to G, chromosome 9 at 90,193,692 bp
  • A to T, chromosome 9 at 118,055,841 bp
  • C to T, chromosome 10 at 44,440,091 bp
  • T to A, chromosome 10 at 62,840,279 bp
  • T to C, chromosome 10 at 88,675,717 bp
  • T to A, chromosome 10 at 118,166,680 bp
  • C to T, chromosome 11 at 8,856,357 bp
  • T to A, chromosome 11 at 23,667,358 bp
  • T to A, chromosome 11 at 101,445,320 bp
  • T to C, chromosome 11 at 115,844,854 bp
  • T to C, chromosome 12 at 53,140,924 bp
  • G to A, chromosome 12 at 83,535,988 bp
  • T to A, chromosome 12 at 84,786,358 bp
  • T to C, chromosome 12 at 103,156,553 bp
  • A to T, chromosome 12 at 119,447,080 bp
  • T to A, chromosome 13 at 4,581,264 bp
  • C to T, chromosome 13 at 24,099,049 bp
  • T to A, chromosome 13 at 54,053,581 bp
  • G to A, chromosome 13 at 74,283,024 bp
  • T to A, chromosome 14 at 7,896,115 bp
  • C to T, chromosome 15 at 89,336,274 bp
  • CAA to CA, chromosome 15 at 96,693,351 bp
  • G to A, chromosome 16 at 35,719,314 bp
  • A to T, chromosome 16 at 36,715,635 bp
  • G to A, chromosome 16 at 87,405,519 bp
  • G to A, chromosome 16 at 92,077,693 bp
  • T to C, chromosome 17 at 57,444,995 bp
  • A to T, chromosome 18 at 37,448,489 bp
  • C to T, chromosome 19 at 9,005,725 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0166 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038442-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.