Strain Name:
C57BL/6J-MtgxR0288Btlr/Mmmh
Stock Number:
038507-MU
Citation ID:
RRID:MMRRC_038507-MU
Other Names:
R0288 (G1), C57BL/6J-MtgxR0288Btlr
Major Collection:

Strain Information

Plekhj1
Name: pleckstrin homology domain containing, family J member 1
Synonyms: 9530063M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78670
VEGA: 10
Homologene: 11389
Pmel
Name: premelanosome protein
Synonyms: Pmel17, gp100, gp87, D12S53Eh, D10H12S53E, Si
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20431
VEGA: 10
Homologene: 5048
Vldlr
Name: very low density lipoprotein receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 22359
Homologene: 443
Rictor
Name: RPTOR independent companion of MTOR, complex 2
Synonyms: 6030405M08Rik, D530039E11Rik, 4921505C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78757
VEGA: 15
Homologene: 34317
Dnmbp
Name: dynamin binding protein
Synonyms: 2410003M15Rik, Tuba, 2410003L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71972
Homologene: 9061
Slc29a1
Name: solute carrier family 29 (nucleoside transporters), member 1
Synonyms: ENT1, NBMPR-sensitive equilibrative nucleoside transporter, 1200014D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 63959
Homologene: 37985
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Kif1b
Name: kinesin family member 1B
Synonyms: D4Mil1e, Kif1b alpha, Kif1b beta, KIF1Bp130, KIF1Bp204, N-3 kinesin, A530096N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16561
Homologene: 99835
Zfp280d
Name: zinc finger protein 280D
Synonyms: Suhw4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235469
Homologene: 17151
Hdac4
Name: histone deacetylase 4
Synonyms: 4932408F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208727
Homologene: 55946
Ankle2
Name: ankyrin repeat and LEM domain containing 2
Synonyms: 1110001J12Rik, D5Ertd585e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71782
Homologene: 35424
Top2a
Name: topoisomerase (DNA) II alpha
Synonyms: DNA Topoisomerase II alpha, Top-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21973
Homologene: 830
Sltm
Name: SAFB-like, transcription modulator
Synonyms: 5730455C01Rik, 9130215G10Rik, 5730555F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66660
VEGA: 9
Homologene: 11696
Rif1
Name: replication timing regulatory factor 1
Synonyms: 5730435J01Rik, 6530403D07Rik, D2Ertd145e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Cyfip2
Name: cytoplasmic FMR1 interacting protein 2
Synonyms: Pir121, 6430511D02Rik, 1500004I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76884
Homologene: 7936
Psip1
Name: PC4 and SFRS1 interacting protein 1
Synonyms: Psip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 101739
HGNC: HGNC:9527
Homologene: 13242
Slc6a3
Name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Synonyms: DAT, Dat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13162
VEGA: 13
Homologene: 55547
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Rsbn1l
Name: round spermatid basic protein 1-like
Synonyms: 8430412F05Rik, C330002G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242860
Homologene: 19435
Chmp1a
Name: charged multivesicular body protein 1A
Synonyms: 2900018H07Rik, Pcoln3, chromatin modifying protein 1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234852
HGNC: HGNC:8740
Homologene: 56240
Camkv
Name: CaM kinase-like vesicle-associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235604
Homologene: 56983
Tbl3
Name: transducin (beta)-like 3
Synonyms: 9430070M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 213773
Homologene: 4711
Amigo2
Name: adhesion molecule with Ig like domain 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105827
VEGA: 15
Homologene: 18649
Dennd1c
Name: DENN/MADD domain containing 1C
Synonyms: 4432409M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70785
VEGA: 17
Homologene: 11773
Ndst3
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Synonyms: 4930511P15Rik, 4921531K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83398
HGNC: HGNC:7682
Homologene: 3513
Klhl14
Name: kelch-like 14
Synonyms: 6330403N15Rik, printor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225266
Homologene: 28121
Vmn1r28
Name: vomeronasal 1 receptor 28
Synonyms: V1rc25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171198
Homologene: 138094
Pkd1l3
Name: polycystic kidney disease 1 like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244646
Homologene: 14627
Miox
Name: myo-inositol oxygenase
Synonyms: RSOR, 0610009I10Rik, C85427, Aldrl6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 56727
Homologene: 9732
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna-1, erythroid, ihj, Spna1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20739
Homologene: 74460
Stk32a
Name: serine/threonine kinase 32A
Synonyms: YANK1, A930015B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269019
VEGA: 18
Homologene: 65357
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: PRIP, ASC2, RAP250, AIB3, NRC, ASC-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56406
Homologene: 137337
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244484
Homologene: 12460
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Cfap44
Name: cilia and flagella associated protein 44
Synonyms: 6330444M21Rik, D16Ertd642e, Wdr52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 212517
Homologene: 75085
Nlrp2
Name: NLR family, pyrin domain containing 2
Synonyms: PYPAF2, E330007A02Rik, Nalp2, Pan1, Nbs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232827
Homologene: 56789
Nhsl1
Name: NHS-like 1
Synonyms: A630035H13Rik, D10Bwg0940e, 5730409E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215819
Homologene: 27834
Ces2c
Name: carboxylesterase 2C
Synonyms: Ces2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234671
HGNC: HGNC:1864
Homologene: 138298
Slc36a1
Name: solute carrier family 36 (proton/amino acid symporter), member 1
Synonyms: Pat1, 5830411H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 215335
Homologene: 121860
Tmem144
Name: transmembrane protein 144
Synonyms: 1110057I03Rik, 5730537D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70652
Homologene: 41250
Gnptab
Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Synonyms: EG432486
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432486
Homologene: 32576
Adgrg3
Name: adhesion G protein-coupled receptor G3
Synonyms: Pb99, A030001G24Rik, Gpr97
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54672
Homologene: 18129
Coil
Name: coilin
Synonyms: p80-coilin, Cln80
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12812
HGNC: HGNC:2184
Homologene: 3413
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-a, Slp2, Slp2-d, Slp2-c, Slp2-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83671
Homologene: 131343
Cyp4f39
Name: cytochrome P450, family 4, subfamily f, polypeptide 39
Synonyms: 4732474A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 320997
VEGA: 17
Homologene: 69814
Zfp36
Name: zinc finger protein 36
Synonyms: Nup475, Zfp-36, Tristetraprolin, Tis11, Ttp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22695
Homologene: 2558
Pcdhb15
Name: protocadherin beta 15
Synonyms: Pcdhb7, PcdhbO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93886
HGNC: HGNC:8692
Homologene: 32429
Cfhr3
Name: complement factor H-related 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 624286
Homologene: 138664
Zfp618
Name: zinc finger protein 618
Synonyms: D430033D05Rik, 2810040O04Rik, 2810031P15Rik, Nedd10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72701
Homologene: 18975
Kcnk3
Name: potassium channel, subfamily K, member 3
Synonyms: cTBAK-1, Task-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16527
HGNC: HGNC:6278
Homologene: 1692
Pdcl2
Name: phosducin-like 2
Synonyms: 1700016K07Rik, 1700010B22Rik, Mgcphlp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 79455
Homologene: 74832
Slc15a5
Name: solute carrier family 15, member 5
Synonyms: 9830102E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 277898
Homologene: 65333
Vmn2r28
Name: vomeronasal 2, receptor 28
Synonyms: EG665255
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 665255
Homologene: 129605
Capn9
Name: calpain 9
Synonyms: GC36, nCL-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73647
HGNC: HGNC:1486
Homologene: 38208
Colq
Name: collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 382864
HGNC: HGNC:2226
Pla2g6
Name: phospholipase A2, group VI
Synonyms: iPLA2, iPLA2beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 53357
HGNC: HGNC:9039
Homologene: 2635
Slc5a7
Name: solute carrier family 5 (choline transporter), member 7
Synonyms: CHT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 63993
VEGA: 17
Homologene: 32516
Dsc2
Name: desmocollin 2
Synonyms: Dsc2b, Dsc2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13506
HGNC: HGNC:3036
Homologene: 8397
Marveld1
Name: MARVEL (membrane-associating) domain containing 1
Synonyms: Mrvldc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 277010
Homologene: 12881
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Dffry, Fafl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 107868
Homologene: 68408
Sry
Name: sex determining region of Chr Y
Synonyms: Tdf, Tdy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 21674
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 91,971,006 bp
  • A to G, chromosome 1 at 139,597,687 bp
  • T to C, chromosome 1 at 174,243,179 bp
  • T to C, chromosome 2 at 52,110,013 bp
  • TGC to TGCGC, chromosome 2 at 155,408,291 bp
  • G to A, chromosome 3 at 79,839,273 bp
  • A to T, chromosome 3 at 123,672,194 bp
  • A to T, chromosome 4 at 63,132,934 bp
  • T to C, chromosome 4 at 83,464,959 bp
  • A to T, chromosome 4 at 149,199,338 bp
  • T to C, chromosome 5 at 20,920,040 bp
  • T to C, chromosome 5 at 30,588,420 bp
  • T to C, chromosome 5 at 76,312,497 bp
  • T to A, chromosome 5 at 110,236,390 bp
  • G to A, chromosome 6 at 58,265,717 bp
  • A to G, chromosome 6 at 138,017,916 bp
  • A to G, chromosome 7 at 5,328,545 bp
  • A to G, chromosome 7 at 5,488,021 bp
  • A to G, chromosome 7 at 28,378,241 bp
  • T to C, chromosome 7 at 90,403,020 bp
  • C to T, chromosome 8 at 54,693,096 bp
  • A to G, chromosome 8 at 95,039,940 bp
  • A to G, chromosome 8 at 104,849,744 bp
  • G to A, chromosome 8 at 109,646,499 bp
  • G to T, chromosome 8 at 123,208,006 bp
  • A to G, chromosome 8 at 124,600,491 bp
  • T to C, chromosome 9 at 67,927,366 bp
  • T to C, chromosome 9 at 70,579,351 bp
  • A to T, chromosome 9 at 72,331,339 bp
  • A to G, chromosome 9 at 107,946,356 bp
  • A to G, chromosome 10 at 18,524,046 bp
  • A to T, chromosome 10 at 80,796,610 bp
  • G to A, chromosome 10 at 88,433,105 bp
  • T to C, chromosome 10 at 128,714,306 bp
  • A to G, chromosome 11 at 46,253,972 bp
  • G to A, chromosome 11 at 55,219,087 bp
  • A to T, chromosome 11 at 66,025,134 bp
  • G to A, chromosome 11 at 88,981,868 bp
  • A to G, chromosome 11 at 99,016,423 bp
  • C to T, chromosome 12 at 7,990,779 bp
  • G to T, chromosome 13 at 73,560,928 bp
  • T to C, chromosome 14 at 31,543,992 bp
  • A to G, chromosome 15 at 6,786,540 bp
  • A to C, chromosome 15 at 79,286,906 bp
  • C to T, chromosome 15 at 89,336,274 bp
  • G to T, chromosome 15 at 97,245,679 bp
  • T to A, chromosome 16 at 44,415,894 bp
  • G to A, chromosome 17 at 24,701,807 bp
  • A to G, chromosome 17 at 32,492,436 bp
  • G to A, chromosome 17 at 45,589,804 bp
  • A to T, chromosome 17 at 54,293,018 bp
  • A to T, chromosome 17 at 57,076,870 bp
  • T to C, chromosome 18 at 20,033,120 bp
  • G to A, chromosome 18 at 21,565,563 bp
  • T to C, chromosome 18 at 37,475,398 bp
  • T to A, chromosome 18 at 43,304,995 bp
  • G to A, chromosome 19 at 27,240,651 bp
  • T to C, chromosome 19 at 42,147,826 bp
  • T to C, chromosome 19 at 43,902,459 bp
  • A to T, chromosome Y at 1,333,606 bp
  • A to T, chromosome Y at 2,662,818 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0288 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038507-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.