Strain Name:
C57BL/6J-MtgxR0367Btlr/Mmmh
Stock Number:
038573-MU
Citation ID:
RRID:MMRRC_038573-MU
Other Names:
R0367 (G1), C57BL/6J-MtgxR0367Btlr
Major Collection:

Gene Information

Limch1
Name: LIM and calponin homology domains 1
Synonyms: 3732412D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77569
Homologene: 18953
Htr2a
Name: 5-hydroxytryptamine (serotonin) receptor 2A
Synonyms: 5-HT2A receptor, Htr-2, Htr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 15558
VEGA: 14
HGNC: HGNC:5293
Homologene: 68073
Ccne2
Name: cyclin E2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12448
HGNC: HGNC:1590
Homologene: 7660
Aasdh
Name: aminoadipate-semialdehyde dehydrogenase
Synonyms: A230062G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231326
Homologene: 71711
Map3k4
Name: mitogen-activated protein kinase kinase kinase 4
Synonyms: MTK1, MAPKKK4, D17Rp17, RP17, D17Rp17e, Mekk4, T-associated sex reversal, Tas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26407
VEGA: 17
HGNC: HGNC:6856
Homologene: 31346
Tm9sf2
Name: transmembrane 9 superfamily member 2
Synonyms: P76, 1500001N15Rik, D14Ertd64e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68059
Homologene: 21004
Gstcd
Name: glutathione S-transferase, C-terminal domain containing
Synonyms: 4933434L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67553
Homologene: 11693
Cpt1c
Name: carnitine palmitoyltransferase 1c
Synonyms: CPT I-C, 9630004I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78070
Homologene: 17561
Samd4b
Name: sterile alpha motif domain containing 4B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233033
Homologene: 35268
G3bp1
Name: GTPase activating protein (SH3 domain) binding protein 1
Synonyms: GAP SH3 binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27041
Homologene: 38096
Setdb1
Name: SET domain, bifurcated 1
Synonyms: ESET, KMT1E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 84505
Homologene: 32157
Lmtk2
Name: lemur tyrosine kinase 2
Synonyms: 2900041G10Rik, KPI-2, cprk, KPI2, A330101P12Rik, BREK, AATYK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231876
Homologene: 8948
Zfp292
Name: zinc finger protein 292
Synonyms: Zn-16, Zn-15, Krox-10, Zfp-15, 9430062L07Rik, 5730450D02Rik, Zfp15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
Lpin2
Name: lipin 2
Synonyms: 2610511G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 64898
Homologene: 8769
Rab5b
Name: RAB5B, member RAS oncogene family
Synonyms: C030027M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19344
VEGA: 10
HGNC: HGNC:9784
Homologene: 104027
Cdc42bpg
Name: CDC42 binding protein kinase gamma (DMPK-like)
Synonyms: MRCKgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240505
Homologene: 28384
Rims2
Name: regulating synaptic membrane exocytosis 2
Synonyms: RIM2, 2810036I15Rik, Syt3-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 116838
VEGA: 15
Homologene: 81639
Alx4
Name: aristaless-like homeobox 4
Synonyms: Aristaless-like 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11695
HGNC: HGNC:450
Homologene: 7229
Syt13
Name: synaptotagmin XIII
Synonyms: 5730409J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 80976
Homologene: 10823
Setd1a
Name: SET domain containing 1A
Synonyms: KMT2F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233904
Homologene: 52251
Strip2
Name: striatin interacting protein 2
Synonyms: Myoscape, D330017J20Rik, Fam40b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320609
Homologene: 66198
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Arhgap19
Name: Rho GTPase activating protein 19
Synonyms: 4933411B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71085
Homologene: 13159
Fads1
Name: fatty acid desaturase 1
Synonyms: 0710001O03Rik, A930006B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76267
VEGA: 19
HGNC: HGNC:3574
Homologene: 22753
Dusp27
Name: dual specificity phosphatase 27 (putative)
Synonyms: C130085G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240892
Homologene: 18949
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Gp2
Name: glycoprotein 2 (zymogen granule membrane)
Synonyms: 2310037I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67133
HGNC: HGNC:4441
Homologene: 133790
Scnn1g
Name: sodium channel, nonvoltage-gated 1 gamma
Synonyms: ENaC gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20278
Homologene: 20280
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, diminished cone electroretinogram, dice, Cpfl8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Fat2
Name: FAT atypical cadherin 2
Synonyms: LOC245827, mKIAA0811, Fath2, EMI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: 1700096C21Rik, sba
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240411
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip-rs6, Naip2, Birc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Antxr2
Name: anthrax toxin receptor 2
Synonyms: cI-35, CMG-2, CMG2, 2310046B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71914
Homologene: 43236
Lyzl6
Name: lysozyme-like 6
Synonyms: 1700023H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69444
Homologene: 10709
Cfap44
Name: cilia and flagella associated protein 44
Synonyms: 6330444M21Rik, D16Ertd642e, Wdr52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 212517
Homologene: 75085
C8a
Name: complement component 8, alpha polypeptide
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230558
HGNC: HGNC:1352
Homologene: 472
Edem1
Name: ER degradation enhancer, mannosidase alpha-like 1
Synonyms: A130059K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 192193
Homologene: 33836
Mocs3
Name: molybdenum cofactor synthesis 3
Synonyms: 1700020H17Rik, Uba4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69372
Homologene: 6108
C130026I21Rik
Name: RIKEN cDNA C130026I21 gene
Synonyms: OTTMUSG00000029174
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 620078
Homologene: 131208
Scamp1
Name: secretory carrier membrane protein 1
Synonyms: 4930505M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 107767
Homologene: 37975
Kcnt1
Name: potassium channel, subfamily T, member 1
Synonyms: slo2, Slack, C030030G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227632
Homologene: 11055
Ddx60
Name: DExD/H box helicase 60
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234311
Homologene: 23031
Slc2a7
Name: solute carrier family 2 (facilitated glucose transporter), member 7
Synonyms: OTTMUSG00000010396
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435818
Homologene: 72470
Hipk3
Name: homeodomain interacting protein kinase 3
Synonyms: DYRK6, FIST3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15259
HGNC: HGNC:4915
Homologene: 55923
Zfp518a
Name: zinc finger protein 518A
Synonyms: 6330417C12Rik, 2810401C22Rik, Zfp518
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72672
VEGA: 19
Homologene: 19378
Olfr859
Name: olfactory receptor 859
Synonyms: GA_x6K02T2PVTD-13548326-13549255, MOR146-3, MOR146-10_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258519
Homologene: 134093
Kcnt2
Name: potassium channel, subfamily T, member 2
Synonyms: E330038N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240776
Homologene: 16121
Pdzrn4
Name: PDZ domain containing RING finger 4
Synonyms: SAMCAP3L, LNX4, 1110017D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239618
VEGA: 15
Homologene: 85433
Myrf
Name: myelin regulatory factor
Synonyms: LOC225908, LOC386531, Gm98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Gpr161
Name: G protein-coupled receptor 161
Synonyms: LOC240888, vl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240888
Homologene: 17824
Olfr1263
Name: olfactory receptor 1263
Synonyms: GA_x6K02T2Q125-51447049-51447969, MOR234-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258790
Homologene: 45043
Lrrc34
Name: leucine rich repeat containing 34
Synonyms: 1700007J06Rik, Spata34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71827
Homologene: 27419
Vmn2r49
Name: vomeronasal 2, receptor 49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 625605
Homologene: 113703
Cend1
Name: cell cycle exit and neuronal differentiation 1
Synonyms: BM88, 1500001H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57754
Homologene: 137316
Dapk2
Name: death-associated protein kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13143
HGNC: HGNC:2675
Homologene: 74940
Olfr51
Name: olfactory receptor 51
Synonyms: ID7, MOR129-3, GA_x6K02T2QP88-4431129-4430206
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18351
Homologene: 133578
Elp5
Name: elongator acetyltransferase complex subunit 5
Synonyms: Clone 13u, Rai12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 54351
Homologene: 10291
Pcare
Name: photoreceptor cilium actin regulator
Synonyms: BC027072
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225004
VEGA: 17
Homologene: 19792
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 85,270,103 bp
  • A to T, chromosome 1 at 140,351,225 bp
  • T to C, chromosome 1 at 165,317,236 bp
  • T to A, chromosome 1 at 166,100,763 bp
  • G to A, chromosome 2 at 25,907,628 bp
  • A to C, chromosome 2 at 90,015,772 bp
  • C to A, chromosome 2 at 92,915,251 bp
  • T to A, chromosome 2 at 93,668,608 bp
  • A to T, chromosome 2 at 104,431,249 bp
  • C to T, chromosome 2 at 168,231,682 bp
  • A to T, chromosome 3 at 30,629,993 bp
  • A to G, chromosome 3 at 95,349,881 bp
  • G to A, chromosome 3 at 132,986,377 bp
  • T to A, chromosome 4 at 11,201,426 bp
  • T to C, chromosome 4 at 34,808,227 bp
  • A to C, chromosome 4 at 104,862,594 bp
  • T to C, chromosome 4 at 150,166,366 bp
  • G to A, chromosome 5 at 66,857,954 bp
  • A to G, chromosome 5 at 76,902,114 bp
  • T to C, chromosome 5 at 98,029,596 bp
  • C to T, chromosome 5 at 144,174,285 bp
  • A to T, chromosome 6 at 29,937,651 bp
  • T to A, chromosome 6 at 108,846,752 bp
  • T to G, chromosome 6 at 146,234,008 bp
  • A to T, chromosome 7 at 9,976,430 bp
  • C to T, chromosome 7 at 28,423,448 bp
  • T to C, chromosome 7 at 44,959,575 bp
  • C to T, chromosome 7 at 119,454,568 bp
  • T to C, chromosome 7 at 121,746,579 bp
  • T to G, chromosome 7 at 127,788,186 bp
  • C to A, chromosome 7 at 141,427,895 bp
  • C to T, chromosome 8 at 15,917,270 bp
  • A to G, chromosome 8 at 45,024,313 bp
  • T to G, chromosome 8 at 62,017,749 bp
  • G to T, chromosome 9 at 19,808,543 bp
  • C to T, chromosome 9 at 66,268,886 bp
  • C to T, chromosome 10 at 128,682,903 bp
  • A to G, chromosome 11 at 51,007,077 bp
  • A to T, chromosome 11 at 55,292,093 bp
  • T to C, chromosome 11 at 55,498,626 bp
  • A to G, chromosome 11 at 69,975,141 bp
  • A to G, chromosome 11 at 103,636,752 bp
  • A to G, chromosome 12 at 75,880,177 bp
  • T to C, chromosome 13 at 94,210,580 bp
  • A to C, chromosome 13 at 100,161,782 bp
  • A to T, chromosome 14 at 74,642,209 bp
  • T to C, chromosome 14 at 122,155,368 bp
  • G to T, chromosome 15 at 39,462,615 bp
  • A to G, chromosome 15 at 92,757,657 bp
  • T to C, chromosome 16 at 44,433,476 bp
  • A to C, chromosome 17 at 12,258,041 bp
  • A to T, chromosome 17 at 71,215,022 bp
  • G to T, chromosome 17 at 71,750,476 bp
  • C to T, chromosome 18 at 77,425,757 bp
  • G to A, chromosome 19 at 6,311,395 bp
  • C to T, chromosome 19 at 10,183,065 bp
  • G to C, chromosome 19 at 10,218,162 bp
  • A to T, chromosome 19 at 40,912,221 bp
  • C to A, chromosome 19 at 41,801,978 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0367 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038573-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.