Strain Name:
C57BL/6J-MtgxR0507Btlr/Mmmh
Stock Number:
038702-MU
Citation ID:
RRID:MMRRC_038702-MU
Other Names:
R0507 (G1), C57BL/6J-MtgxR0507Btlr
Major Collection:

Strain Information

Uchl3
Name: ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50933
VEGA: 14
Homologene: 4377
Dicer1
Name: dicer 1, ribonuclease type III
Synonyms: 1110006F08Rik, D12Ertd7e, Dicer1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 192119
VEGA: 12
Homologene: 13251
Egf
Name: epidermal growth factor
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13645
HGNC: HGNC:3229
Homologene: 1483
Wdr73
Name: WD repeat domain 73
Synonyms: 1200011I23Rik, 2410008B13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71968
Homologene: 41899
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, Zap3, A930013E17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56531
Homologene: 87707
Uhmk1
Name: U2AF homology motif (UHM) kinase 1
Synonyms: KIS, Kist, OTTMUSG00000021542, C820018A03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16589
Homologene: 7801
Pard3
Name: par-3 family cell polarity regulator
Synonyms: ASIP, D8Ertd580e, PAR-3, Par3, Pard3a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 93742
Homologene: 10489
Cpne3
Name: copine III
Synonyms: PRO1071, CPN3, 5730450C07Rik, 5430428M23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70568
HGNC: HGNC:2316
Homologene: 20839
Cep97
Name: centrosomal protein 97
Synonyms: 4932439K18Rik, E130116N02Rik, 2810403B08Rik, Lrriq2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74201
Homologene: 11579
Xpo1
Name: exportin 1
Synonyms: Crm1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103573
Homologene: 2554
Cct2
Name: chaperonin containing TCP1 subunit 2
Synonyms: Cctb
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12461
VEGA: 10
HGNC: HGNC:1615
Homologene: 4696
Akap9
Name: A kinase anchor protein 9
Synonyms: AKAP450, 5730481H23Rik, G1-448-15, repro12, mei2-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Ttk
Name: Ttk protein kinase
Synonyms: Esk1, Mps1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22137
Homologene: 2489
Bsx
Name: brain specific homeobox
Synonyms: Bsx1b, Bsx1a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244813
Homologene: 65347
Dcdc2a
Name: doublecortin domain containing 2a
Synonyms: RU2, Dcdc2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 195208
Homologene: 9483
Twf1
Name: twinfilin actin binding protein 1
Synonyms: A6, actin monomer-binding protein, twinfilin, Twinfilin-1, Ptk9
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19230
HGNC: HGNC:9620
Homologene: 48140
Themis
Name: thymocyte selection associated
Synonyms: E430004N04Rik, Tsepa, Gasp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 210757
Homologene: 72287
Sec13
Name: SEC13 homolog, nuclear pore and COPII coat complex component
Synonyms: 1110003H02Rik, Sec13r, Sec13l1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 110379
Homologene: 6479
Ralbp1
Name: ralA binding protein 1
Synonyms: Rip1, RLIP76
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19765
VEGA: 17
HGNC: HGNC:9841
Homologene: 4940
Ddx17
Name: DEAD box helicase 17
Synonyms: A430025E01Rik, LOC381024, 2610007K22Rik, p72, DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67040
VEGA: 15
HGNC: HGNC:2740
Homologene: 101101
Ppp1r13l
Name: protein phosphatase 1, regulatory subunit 13 like
Synonyms: NFkB interacting protein 1, wa3, IASPP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 333654
Homologene: 84635
Pi16
Name: peptidase inhibitor 16
Synonyms: 1200009H11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74116
Homologene: 134317
Thsd1
Name: thrombospondin, type I, domain 1
Synonyms: 4833423O18Rik, Tmtsp
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 56229
Homologene: 10264
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Cx3cr1
Name: C-X3-C motif chemokine receptor 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13051
VEGA: 9
HGNC: HGNC:2558
Homologene: 20350
Steap3
Name: STEAP family member 3
Synonyms: 1010001D01Rik, pHyde
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68428
Homologene: 10084
Myof
Name: myoferlin
Synonyms: 2310051D19Rik, E030042N20Rik, Fer1l3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80892
Homologene: 23477
Fyb1
Name: FYN binding protein 1
Synonyms: FYB-120/130, ADAP, B630013F22Rik, Fyb
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 23880
HGNC: HGNC:4036
Homologene: 22664
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: CD169, Siglec-1, Sn
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20612
Homologene: 124458
Or9q1
Name: olfactory receptor family 9 subfamily Q member 1
Synonyms: GA_x6K02T2RE5P-4160554-4159619, MOR212-4P, Olfr1500
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258097
Homologene: 72644
Slc4a3
Name: solute carrier family 4 (anion exchanger), member 3
Synonyms: Ae3, A930038D23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20536
Homologene: 129474
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329178
Homologene: 122243
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212167
Homologene: 45504
Gucy2d
Name: guanylate cyclase 2d
Synonyms: guanylyl cyclase D
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14918
Homologene: 71540
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242627
Homologene: 135888
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Mbd6
Name: methyl-CpG binding domain protein 6
Synonyms: D10Wsu93e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 110962
Homologene: 14171
Adamts16
Name: ADAM metallopeptidase with thrombospondin type 1 motif 16
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 271127
Homologene: 15146
Or5b105
Name: olfactory receptor family 5 subfamily B member 105
Synonyms: GA_x6K02T2RE5P-3430689-3429787, MOR202-24, EG667271, Olfr1458
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 667271
HGNC: HGNC:8324
Cdkl4
Name: cyclin dependent kinase like 4
Synonyms: LOC381113
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381113
VEGA: 17
Homologene: 28725
Or6c1b
Name: olfactory receptor family 6 subfamily C member 1B
Synonyms: GA_x6K02T2PULF-11116958-11117896, MOR111-5, Olfr786
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258542
HGNC: HGNC:8355
Homologene: 133582
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628870
Homologene: 46008
Mroh3
Name: maestro heat-like repeat family member 3
Synonyms: 2310006M14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76422
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 435626
Homologene: 52359
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, D10Bwg1379e, BIG3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Tgm6
Name: transglutaminase 6
Synonyms: TGM3L
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241636
Homologene: 27970
Gbp2
Name: guanylate binding protein 2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14469
Homologene: 10289
Palm3
Name: paralemmin 3
Synonyms: 4432412L15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74337
Homologene: 53493
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: NACK, D8Ertd82e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244418
Homologene: 18256
Matcap1
Name: microtubule associated tyrosine carboxypeptidase 1
Synonyms: MATCAP, 4931428F04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74356
Homologene: 47588
Icam4
Name: intercellular adhesion molecule 4, Landsteiner-Wiener blood group
Synonyms: Cd242, 1810015M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 78369
VEGA: 9
HGNC: HGNC:5347
Homologene: 74401
Cep250
Name: centrosomal protein 250
Synonyms: Inmp, B230210E21Rik, Cep2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Zfp512b
Name: zinc finger protein 512B
Synonyms: LOC269401, Znf512b
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269401
Homologene: 69314
Vps16
Name: VSP16 CORVET/HOPS core subunit
Synonyms: 1810074M16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 80743
Homologene: 7116
Vmn1r200
Name: vomeronasal 1 receptor 200
Synonyms: V1rh3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171246
Homologene: 110880
Negr1
Name: neuronal growth regulator 1
Synonyms: 5330422G01Rik, Ntra, neurotractin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320840
Homologene: 41447
Rpe
Name: ribulose-5-phosphate-3-epimerase
Synonyms: 5730518J08Rik, 2810429B02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66646
Homologene: 12005
Vash2
Name: vasohibin 2
Synonyms: B130052G07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226841
Homologene: 57005
Or52n4b
Name: olfactory receptor family 52 subfamily N member 4B
Synonyms: GA_x6K02T2PBJ9-10874315-10875286, MOR34-9, MOR34-8P, MOR34-12, MOR34-9, Olfr1548, Olfr503
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259143
Homologene: 121509
Abca7
Name: ATP-binding cassette, sub-family A member 7
Synonyms: Abc51
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Lyz1
Name: lysozyme 1
Synonyms: Lzp-s, renal amyloidosis, Lyz
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17110
VEGA: 10
HGNC: HGNC:6740
Homologene: 121490
Smyd4
Name: SET and MYND domain containing 4
Synonyms: G430029E23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319822
Homologene: 35098
Rnf182
Name: ring finger protein 182
Synonyms: C630023L15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 328234
Homologene: 17656
Ncald
Name: neurocalcin delta
Synonyms: D030020D09Rik, D15Ertd412e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 52589
HGNC: HGNC:7655
Homologene: 49978
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 66,527,893 bp
  • C to T, chromosome 1 at 66,715,141 bp
  • T to C, chromosome 1 at 74,146,716 bp
  • T to A, chromosome 1 at 75,556,081 bp
  • C to T, chromosome 1 at 120,241,583 bp
  • A to T, chromosome 1 at 136,190,980 bp
  • A to G, chromosome 1 at 170,207,191 bp
  • G to T, chromosome 1 at 190,966,918 bp
  • G to A, chromosome 2 at 130,138,831 bp
  • T to C, chromosome 2 at 130,437,712 bp
  • C to T, chromosome 2 at 131,074,525 bp
  • T to A, chromosome 2 at 150,268,124 bp
  • C to T, chromosome 2 at 155,992,532 bp
  • A to T, chromosome 2 at 177,314,532 bp
  • C to A, chromosome 2 at 181,584,964 bp
  • C to T, chromosome 3 at 5,400,988 bp
  • T to C, chromosome 3 at 129,681,179 bp
  • G to T, chromosome 3 at 142,630,033 bp
  • T to A, chromosome 3 at 156,562,225 bp
  • C to T, chromosome 4 at 19,532,544 bp
  • T to C, chromosome 4 at 113,567,930 bp
  • G to A, chromosome 5 at 4,069,043 bp
  • C to T, chromosome 5 at 21,269,963 bp
  • A to T, chromosome 6 at 113,735,119 bp
  • T to C, chromosome 7 at 19,375,814 bp
  • T to C, chromosome 7 at 80,891,846 bp
  • C to A, chromosome 7 at 98,459,002 bp
  • T to C, chromosome 7 at 108,545,085 bp
  • T to C, chromosome 8 at 16,185,344 bp
  • T to A, chromosome 8 at 22,258,679 bp
  • A to G, chromosome 8 at 36,104,123 bp
  • A to G, chromosome 8 at 84,028,329 bp
  • T to C, chromosome 8 at 105,284,719 bp
  • T to A, chromosome 8 at 127,371,486 bp
  • C to A, chromosome 9 at 21,029,503 bp
  • A to G, chromosome 9 at 40,876,500 bp
  • T to G, chromosome 9 at 83,868,067 bp
  • C to A, chromosome 9 at 120,051,956 bp
  • T to C, chromosome 10 at 18,591,621 bp
  • T to A, chromosome 10 at 28,781,832 bp
  • A to G, chromosome 10 at 74,621,297 bp
  • T to A, chromosome 10 at 80,002,821 bp
  • A to G, chromosome 10 at 107,866,740 bp
  • A to T, chromosome 10 at 117,055,246 bp
  • A to T, chromosome 10 at 117,289,117 bp
  • A to G, chromosome 10 at 127,283,520 bp
  • A to T, chromosome 10 at 129,437,288 bp
  • T to C, chromosome 11 at 23,294,682 bp
  • T to C, chromosome 11 at 59,029,341 bp
  • T to A, chromosome 11 at 75,399,708 bp
  • T to A, chromosome 12 at 85,029,112 bp
  • A to G, chromosome 12 at 104,691,658 bp
  • G to A, chromosome 13 at 22,395,548 bp
  • A to G, chromosome 13 at 25,102,589 bp
  • T to G, chromosome 13 at 43,668,347 bp
  • T to C, chromosome 13 at 70,768,647 bp
  • T to A, chromosome 14 at 101,667,007 bp
  • A to G, chromosome 15 at 6,634,816 bp
  • T to G, chromosome 15 at 37,397,284 bp
  • A to T, chromosome 15 at 76,172,783 bp
  • A to G, chromosome 15 at 79,537,557 bp
  • A to G, chromosome 15 at 94,585,530 bp
  • A to T, chromosome 16 at 32,751,069 bp
  • A to T, chromosome 16 at 55,905,882 bp
  • G to A, chromosome 17 at 29,327,852 bp
  • G to A, chromosome 17 at 65,849,960 bp
  • T to C, chromosome 17 at 80,543,808 bp
  • G to A, chromosome 19 at 13,103,278 bp
  • T to A, chromosome 19 at 13,827,776 bp
  • A to G, chromosome 19 at 37,901,277 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0507 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038702-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.