Strain Name:
C57BL/6J-MtgxR0564Btlr/Mmmh
Stock Number:
038755-MU
Citation ID:
RRID:MMRRC_038755-MU
Other Names:
R0564 (G1), C57BL/6J-MtgxR0564Btlr
Major Collection:

Gene Information

Sema3e
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: Semah
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20349
Homologene: 8247
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: b2b1562Clo, my, 6030440P17Rik, ne, 8430406N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242022
Homologene: 18454
Top1
Name: topoisomerase (DNA) I
Synonyms: D130064I21Rik, Top-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 21969
Homologene: 2467
Cwc27
Name: CWC27 spliceosome-associated protein
Synonyms: 3110009E13Rik, NY-CO-10, Sdccag10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 67285
Homologene: 21192
Pdk1
Name: pyruvate dehydrogenase kinase, isoenzyme 1
Synonyms: D530020C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228026
HGNC: HGNC:8809
Homologene: 134437
Apbb2
Name: amyloid beta (A4) precursor protein-binding, family B, member 2
Synonyms: TR2L, Zfra, Rirl1, 2310007D03Rik, FE65L1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11787
HGNC: HGNC:582
Homologene: 32079
Srrm1
Name: serine/arginine repetitive matrix 1
Synonyms: SRm160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 51796
Ankib1
Name: ankyrin repeat and IBR domain containing 1
Synonyms: 2310061P20Rik, 4631416I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70797
Homologene: 19076
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, D630005A10Rik, A430040A19Rik, Bruce, A430032G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12211
Homologene: 7248
Dip2b
Name: disco interacting protein 2 homolog B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239667
Homologene: 72227
Esf1
Name: ESF1 nucleolar pre-rRNA processing protein homolog
Synonyms: 2610101J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66580
Homologene: 5717
Mfn2
Name: mitofusin 2
Synonyms: hypertension related protein 1, D630023P19Rik, Fzo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 170731
Homologene: 8915
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, 2310003F20Rik, Garnl1, Tulip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56784
VEGA: 12
Homologene: 84805
Cep135
Name: centrosomal protein 135
Synonyms: Cep4, LOC381644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381644
Homologene: 45709
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223435
VEGA: 15
Homologene: 20847
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: Zzank1, 2210008I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 76580
Homologene: 16062
Ccdc126
Name: coiled-coil domain containing 126
Synonyms: 6330407D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 57895
Homologene: 16342
Mpp3
Name: membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
Synonyms: Dlgh3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13384
HGNC: HGNC:7221
Homologene: 31065
Fbln1
Name: fibulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14114
HGNC: HGNC:3600
Homologene: 21295
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: 4432416O06Rik, DHC2, b2b414Clo, Dnchc2, m407Asp, m152Asp, D030010H02Rik, D330044F14Rik, DHC1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Tm9sf3
Name: transmembrane 9 superfamily member 3
Synonyms: Smbp, 1810073M23Rik, 2810031D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107358
VEGA: 19
Homologene: 10588
Smap2
Name: small ArfGAP 2
Synonyms: Smap2, Smap1l, 1810031K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69780
Homologene: 41489
Atad2
Name: ATPase family, AAA domain containing 2
Synonyms: 2610509G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 70472
VEGA: 15
Homologene: 6044
Mtmr4
Name: myotubularin related protein 4
Synonyms: ESTM44, FYVE-DSP2, ZFYVE11, FYVE zinc finger phosphatase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 170749
HGNC: HGNC:7452
Homologene: 3440
D230025D16Rik
Name: RIKEN cDNA D230025D16 gene
Synonyms: Lin10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234678
Homologene: 11864
Sh2d3c
Name: SH2 domain containing 3C
Synonyms: Nsp3, Shep1, Cas/HEF1-associated signal transducer, Chat, SH2-containing Eph receptor-binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27387
Homologene: 69145
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Mcc
Name: mutated in colorectal cancers
Synonyms: D18Ertd451e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 328949
HGNC: HGNC:6935
Homologene: 20539
Snrk
Name: SNF related kinase
Synonyms: SNRK, 2010012F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20623
Homologene: 9797
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Siah2
Name: siah E3 ubiquitin protein ligase 2
Synonyms: Sinh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20439
Homologene: 21053
Iigp1
Name: interferon inducible GTPase 1
Synonyms: 2900074L10Rik, Irga6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 60440
VEGA: 18
Cdc16
Name: CDC16 cell division cycle 16
Synonyms: 2810431D22Rik, 2700071J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 69957
HGNC: HGNC:1720
Homologene: 2899
Nlrp4b
Name: NLR family, pyrin domain containing 4B
Synonyms: Nalp-gamma, Nalp4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 210045
Homologene: 65242
Phxr4
Name: per-hexamer repeat gene 4
Synonyms: Sp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 18689
VEGA: 9
Tmem184c
Name: transmembrane protein 184C
Synonyms: 8430433H16Rik, Tmem34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234463
Homologene: 32403
Tmem132d
Name: transmembrane protein 132D
Synonyms: C630028F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243274
Homologene: 71684
Gm4922
Name: predicted gene 4922
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237300
VEGA: 10
Homologene: 50497
Hist1h1t
Name: histone cluster 1, H1t
Synonyms: H1ft
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 107970
HGNC: HGNC:4720
Homologene: 3889
Rad51ap2
Name: RAD51 associated protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 209550
VEGA: 12
Homologene: 85245
Cstdc6
Name: cystatin domain containing 6
Synonyms: BC117090, Gm1975
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 100038854
VEGA: 16
HGNC: HGNC:2481
Homologene: 104045
Micu2
Name: mitochondrial calcium uptake 2
Synonyms: 4833427E09Rik, Efha1, 1110008L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 68514
VEGA: 14
Homologene: 12516
Alox12
Name: arachidonate 12-lipoxygenase
Synonyms: P-12LO, 9930022G08Rik, Alox12p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11684
HGNC: HGNC:429
Homologene: 560
Luzp2
Name: leucine zipper protein 2
Synonyms: 9330154K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233271
Homologene: 45618
Upf3a
Name: UPF3 regulator of nonsense transcripts homolog A (yeast)
Synonyms: UPF3, 4930546M19Rik, 2600001C03Rik, RENT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67031
Homologene: 23395
Dpysl2
Name: dihydropyrimidinase-like 2
Synonyms: Ulip2, DRP2, TOAD-64, Crmp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12934
HGNC: HGNC:3014
Homologene: 74392
Tmem235
Name: transmembrane protein 235
Synonyms: Gm12581, Tmem235, Cldn27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 546519
Homologene: 53069
Rps27
Name: ribosomal protein S27
Synonyms: 3200001M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 57294
Homologene: 136393
Olfr551
Name: olfactory receptor 551
Synonyms: MOR29-1, GA_x6K02T2PBJ9-5307445-5306498
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258750
Homologene: 17381
Adamtsl5
Name: ADAMTS-like 5
Synonyms: Thsd6, 2010109H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66548
Homologene: 19803
Olfr809
Name: olfactory receptor 809
Synonyms: GA_x6K02T2PULF-11454600-11455541, MOR108-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258321
Homologene: 138308
Tmem267
Name: transmembrane protein 267
Synonyms: Gm7120
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 633640
Homologene: 49708
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 90,807,734 bp
  • G to A, chromosome 2 at 32,753,052 bp
  • G to A, chromosome 2 at 71,880,039 bp
  • A to T, chromosome 2 at 140,158,586 bp
  • G to A, chromosome 2 at 160,714,265 bp
  • A to G, chromosome 3 at 53,656,109 bp
  • T to C, chromosome 3 at 58,676,235 bp
  • A to G, chromosome 3 at 90,212,923 bp
  • G to A, chromosome 4 at 120,976,977 bp
  • G to A, chromosome 4 at 135,342,486 bp
  • A to G, chromosome 4 at 147,883,255 bp
  • C to T, chromosome 4 at 155,659,460 bp
  • A to G, chromosome 5 at 3,729,655 bp
  • T to A, chromosome 5 at 14,236,085 bp
  • A to T, chromosome 5 at 66,452,250 bp
  • G to A, chromosome 5 at 76,615,710 bp
  • G to T, chromosome 5 at 76,638,949 bp
  • C to T, chromosome 5 at 127,784,778 bp
  • T to C, chromosome 6 at 49,334,142 bp
  • A to G, chromosome 7 at 10,714,658 bp
  • A to G, chromosome 7 at 54,835,962 bp
  • T to C, chromosome 7 at 102,588,531 bp
  • A to T, chromosome 8 at 13,781,618 bp
  • A to G, chromosome 8 at 13,795,656 bp
  • A to T, chromosome 8 at 77,606,160 bp
  • T to A, chromosome 8 at 105,239,971 bp
  • A to T, chromosome 9 at 7,139,432 bp
  • A to T, chromosome 9 at 13,431,697 bp
  • C to T, chromosome 9 at 122,166,544 bp
  • T to A, chromosome 10 at 18,784,065 bp
  • A to G, chromosome 10 at 80,344,847 bp
  • T to G, chromosome 10 at 129,776,136 bp
  • T to A, chromosome 11 at 70,252,836 bp
  • T to A, chromosome 11 at 87,598,888 bp
  • T to G, chromosome 11 at 102,005,347 bp
  • A to T, chromosome 11 at 117,860,848 bp
  • A to G, chromosome 11 at 118,082,981 bp
  • T to A, chromosome 12 at 11,457,896 bp
  • A to T, chromosome 12 at 55,782,885 bp
  • G to T, chromosome 13 at 23,696,324 bp
  • C to A, chromosome 13 at 104,661,357 bp
  • A to T, chromosome 13 at 119,492,639 bp
  • A to G, chromosome 14 at 57,919,374 bp
  • A to T, chromosome 14 at 66,805,446 bp
  • T to C, chromosome 15 at 27,805,822 bp
  • C to A, chromosome 15 at 58,125,833 bp
  • T to A, chromosome 15 at 85,227,107 bp
  • C to A, chromosome 15 at 100,162,719 bp
  • A to T, chromosome 16 at 36,322,984 bp
  • T to A, chromosome 17 at 74,625,243 bp
  • A to G, chromosome 18 at 44,468,507 bp
  • G to A, chromosome 18 at 60,390,451 bp
  • A to G, chromosome 19 at 41,245,525 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0564 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038755-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.