Strain Name:
C57BL/6J-MtgxR0573Btlr/Mmmh
Stock Number:
038763-MU
Citation ID:
RRID:MMRRC_038763-MU
Other Names:
R0573 (G1), C57BL/6J-MtgxR0573Btlr
Major Collection:

Gene Information

Il21r
Name: interleukin 21 receptor
Synonyms: NILR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 60504
HGNC: HGNC:6006
Homologene: 11040
Dgka
Name: diacylglycerol kinase, alpha
Synonyms: Dagk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13139
VEGA: 10
HGNC: HGNC:2849
Homologene: 1028
Trp53bp1
Name: transformation related protein 53 binding protein 1
Synonyms: p53BP1, 53BP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27223
Homologene: 4137
Gpr21
Name: G protein-coupled receptor 21
Synonyms: C230004C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 338346
HGNC: HGNC:4476
Homologene: 74546
Dlgap4
Name: DLG associated protein 4
Synonyms: DAP4, SAP90/PSD-95-associated protein 4, PSD-95/SAP90 binding protein 4, Sapap4, WBP16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228836
Homologene: 8935
Orc4
Name: origin recognition complex, subunit 4
Synonyms: Orc4P, Orc4, Orc4l, mMmORC4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26428
HGNC: HGNC:8490
Homologene: 8059
Rexo1
Name: REX1, RNA exonuclease 1
Synonyms: 2610511M11Rik, 1700021P10Rik, Rex1, Tceb3bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66932
Homologene: 41391
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: 3110031G15Rik, 6030460N08Rik, 2610511G22Rik, GMAP-210, TRIP230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109181
Homologene: 20897
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: A330063D19Rik, 1810014J18Rik, AD013, 9030205D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109151
Homologene: 11844
Fnbp1
Name: formin binding protein 1
Synonyms: FBP1, FBP17, 1110057E06Rik, 2210010H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14269
Homologene: 100983
Prpf8
Name: pre-mRNA processing factor 8
Synonyms: DBF3/PRP8, Prp8, D11Bwg0410e, Sfprp8l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192159
Homologene: 4706
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: 2610301F02Rik, ENSMUSG00000075261, CAMDI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545428
Homologene: 52149
Stx3
Name: syntaxin 3
Synonyms: Syn-3, syntaxin 3A, syntaxin 3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20908
Homologene: 80191
Basp1
Name: brain abundant, membrane attached signal protein 1
Synonyms: Ckap3, CAP-23, CAP23, 2610024P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70350
VEGA: 15
HGNC: HGNC:957
Homologene: 38168
Mmadhc
Name: methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
Synonyms: 2010311D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 109129
Homologene: 9248
Pwp2
Name: PWP2 periodic tryptophan protein homolog (yeast)
Synonyms: 6530411D08Rik, Pwp2h, Pwp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 110816
VEGA: 10
HGNC: HGNC:9711
Homologene: 3702
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: 2610100B16Rik, Ten-m3, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Trim33
Name: tripartite motif-containing 33
Synonyms: Tif1g, 8030451N04Rik, ectodermin, Ecto
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 94093
Homologene: 9296
Eml5
Name: echinoderm microtubule associated protein like 5
Synonyms: C130068M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319670
VEGA: 12
Homologene: 26807
Colec12
Name: collectin sub-family member 12
Synonyms: Scara4, SRCL, CL-P1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 140792
VEGA: 18
Homologene: 34248
Zp2
Name: zona pellucida glycoprotein 2
Synonyms: Zp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22787
Homologene: 48194
Asic4
Name: acid-sensing (proton-gated) ion channel family member 4
Synonyms: Accn4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241118
Homologene: 11166
Col4a3
Name: collagen, type IV, alpha 3
Synonyms: tumstatin, alpha3(IV)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12828
HGNC: HGNC:2204
Homologene: 68033
Morn1
Name: MORN repeat containing 1
Synonyms: 4930417P05Rik, 2900057D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76866
Homologene: 11757
Clcn1
Name: chloride channel, voltage-sensitive 1
Synonyms: SMCC1, nmf355, NMF355, Clc-1, Clc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12723
HGNC: HGNC:2019
Homologene: 63
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Dchs1
Name: dachsous cadherin related 1
Synonyms: 3110041P15Rik, C130033F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Gm5422
Name: predicted pseudogene 5422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432448
VEGA: 10
Myoc
Name: myocilin
Synonyms: TIGR, GLC1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17926
HGNC: HGNC:7610
Homologene: 220
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Adcy8
Name: adenylate cyclase 8
Synonyms: AC8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11514
VEGA: 15
HGNC: HGNC:239
Homologene: 37443
Egflam
Name: EGF-like, fibronectin type III and laminin G domains
Synonyms: nectican, pikachurin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 268780
Homologene: 65044
Nlrp4b
Name: NLR family, pyrin domain containing 4B
Synonyms: Nalp-gamma, Nalp4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210045
Homologene: 65242
Olfr1105
Name: olfactory receptor 1105
Synonyms: GA_x6K02T2Q125-48521031-48520093, MOR0-6P, MOR172-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258085
Homologene: 121541
Zcchc4
Name: zinc finger, CCHC domain containing 4
Synonyms: 4930449I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 78796
Homologene: 14632
Ptprt
Name: protein tyrosine phosphatase, receptor type, T
Synonyms: RPTPrho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19281
HGNC: HGNC:9682
Homologene: 56924
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 628870
Homologene: 46008
Osbpl6
Name: oxysterol binding protein-like 6
Synonyms: ORP-6, 1110062M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99031
Homologene: 101447
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, BIG3, D10Bwg1379e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Psd2
Name: pleckstrin and Sec7 domain containing 2
Synonyms: 6330404E20Rik, EFA6C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 74002
Homologene: 12522
Gfra3
Name: glial cell line derived neurotrophic factor family receptor alpha 3
Synonyms: GFR alpha-3, GFRalpha3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 14587
VEGA: 18
HGNC: HGNC:4245
Homologene: 1146
Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Synonyms: 5830428L06Rik, PI3Kgamma, PI(3)Kgamma, PI3Kgamma, p110gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 30955
HGNC: HGNC:8978
Homologene: 68269
B020004J07Rik
Name: RIKEN cDNA B020004J07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 545662
Homologene: 128627
Col16a1
Name: collagen, type XVI, alpha 1
Synonyms: A530052M23Rik, 2700007F12Rik, [a]1 (XVI) collagen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 107581
HGNC: HGNC:2193
Homologene: 1397
Ceacam20
Name: carcinoembryonic antigen-related cell adhesion molecule 20
Synonyms: 9130012D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71601
Homologene: 19010
Dsg1c
Name: desmoglein 1 gamma
Synonyms: Dsg6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 211924
HGNC: HGNC:3048
Adam6b
Name: a disintegrin and metallopeptidase domain 6B
Synonyms: 4930523C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238405
Homologene: 128362
Nags
Name: N-acetylglutamate synthase
Synonyms: 1700120E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217214
Homologene: 77363
Olfr1449
Name: olfactory receptor 1449
Synonyms: MOR202-34, GA_x6K02T2RE5P-3264213-3265157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258300
Homologene: 17184
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Nalp5, Op1, Mater
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23968
Homologene: 65105
Setd4
Name: SET domain containing 4
Synonyms: ORF21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224440
HGNC: HGNC:1258
Homologene: 41173
Cbll1
Name: Casitas B-lineage lymphoma-like 1
Synonyms: c-Cbl-like, Hakai
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104836
Homologene: 11734
Pde3a
Name: phosphodiesterase 3A, cGMP inhibited
Synonyms: A930022O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54611
HGNC: HGNC:8778
Homologene: 708
Tuba4a
Name: tubulin, alpha 4A
Synonyms: Tuba4, M[a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22145
Homologene: 68496
Pnliprp1
Name: pancreatic lipase related protein 1
Synonyms: Plrp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18946
VEGA: 19
HGNC: HGNC:9156
Homologene: 21253
Ccdc65
Name: coiled-coil domain containing 65
Synonyms: 4933417K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105833
VEGA: 15
Homologene: 13226
Tas2r102
Name: taste receptor, type 2, member 102
Synonyms: mt2r51, Tas2r2, mGR02, STC 9-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387339
Homologene: 41543
Rgs20
Name: regulator of G-protein signaling 20
Synonyms: 2900073E09Rik, Rgsz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 58175
Homologene: 2745
Tmem33
Name: transmembrane protein 33
Synonyms: 5430406L04Rik, 2700052H22Rik, 1110006G02Rik, 2410089A21Rik, 1600019D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67878
Homologene: 10018
Rassf4
Name: Ras association (RalGDS/AF-6) domain family member 4
Synonyms: 3830411C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213391
Homologene: 12926
Hspb2
Name: heat shock protein 2
Synonyms: 2810021G24Rik, 27kDa, HSP27, MKBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69253
VEGA: 9
HGNC: HGNC:5247
Homologene: 68189
Asb3
Name: ankyrin repeat and SOCS box-containing 3
Synonyms: 2400011J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 65257
Homologene: 9391
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 5,020,814 bp
  • T to C, chromosome 1 at 75,216,373 bp
  • T to A, chromosome 1 at 75,469,102 bp
  • C to A, chromosome 1 at 82,716,363 bp
  • T to C, chromosome 1 at 105,653,177 bp
  • T to C, chromosome 1 at 162,648,674 bp
  • C to A, chromosome 2 at 31,058,978 bp
  • T to A, chromosome 2 at 37,517,544 bp
  • C to T, chromosome 2 at 48,917,273 bp
  • T to A, chromosome 2 at 50,292,835 bp
  • A to T, chromosome 2 at 76,590,391 bp
  • A to T, chromosome 2 at 77,039,493 bp
  • A to G, chromosome 2 at 87,033,468 bp
  • A to G, chromosome 2 at 121,228,172 bp
  • G to A, chromosome 2 at 125,389,249 bp
  • A to G, chromosome 2 at 156,746,191 bp
  • T to C, chromosome 2 at 161,551,748 bp
  • A to G, chromosome 3 at 103,351,990 bp
  • A to C, chromosome 4 at 101,835,414 bp
  • A to T, chromosome 4 at 130,068,475 bp
  • T to A, chromosome 4 at 155,111,016 bp
  • A to G, chromosome 5 at 52,795,979 bp
  • T to C, chromosome 5 at 67,264,260 bp
  • T to A, chromosome 6 at 42,313,045 bp
  • C to T, chromosome 6 at 116,647,555 bp
  • T to A, chromosome 6 at 132,762,673 bp
  • G to T, chromosome 6 at 141,492,231 bp
  • A to G, chromosome 7 at 10,714,215 bp
  • T to A, chromosome 7 at 19,986,668 bp
  • T to A, chromosome 7 at 23,417,631 bp
  • T to C, chromosome 7 at 105,758,778 bp
  • C to T, chromosome 7 at 120,135,470 bp
  • A to G, chromosome 7 at 125,625,285 bp
  • T to C, chromosome 8 at 48,674,399 bp
  • T to A, chromosome 8 at 90,998,595 bp
  • G to T, chromosome 9 at 50,751,364 bp
  • T to A, chromosome 10 at 18,599,288 bp
  • T to A, chromosome 10 at 31,250,160 bp
  • G to A, chromosome 10 at 78,182,686 bp
  • A to G, chromosome 10 at 80,544,850 bp
  • A to C, chromosome 10 at 107,780,988 bp
  • A to G, chromosome 10 at 128,737,007 bp
  • T to A, chromosome 11 at 31,061,406 bp
  • G to A, chromosome 11 at 59,036,079 bp
  • A to G, chromosome 11 at 75,490,654 bp
  • A to G, chromosome 11 at 102,146,979 bp
  • A to T, chromosome 12 at 31,490,540 bp
  • C to A, chromosome 12 at 32,197,197 bp
  • A to C, chromosome 12 at 98,824,772 bp
  • A to G, chromosome 12 at 101,886,860 bp
  • A to T, chromosome 12 at 113,491,658 bp
  • A to T, chromosome 15 at 7,242,425 bp
  • G to T, chromosome 15 at 25,364,862 bp
  • A to T, chromosome 15 at 64,822,195 bp
  • T to C, chromosome 15 at 98,721,049 bp
  • A to G, chromosome 16 at 93,589,946 bp
  • C to A, chromosome 18 at 9,858,650 bp
  • T to A, chromosome 18 at 20,279,241 bp
  • T to A, chromosome 18 at 34,691,615 bp
  • T to A, chromosome 18 at 35,980,493 bp
  • G to T, chromosome 19 at 11,785,746 bp
  • T to C, chromosome 19 at 12,935,260 bp
  • C to T, chromosome 19 at 58,734,882 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0573 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038763-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.