Strain Name:
C57BL/6J-MtgxR0634Btlr/Mmmh
Stock Number:
038823-MU
Citation ID:
RRID:MMRRC_038823-MU
Other Names:
R0634 (G1), C57BL/6J-MtgxR0634Btlr
Major Collection:

Gene Information

Sox9
Name: SRY (sex determining region Y)-box 9
Synonyms: 2010306G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20682
Homologene: 294
Map2k6
Name: mitogen-activated protein kinase kinase 6
Synonyms: MAP kinase kinase 6, MKK6, SAPKK3, Prkmk6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 26399
HGNC: HGNC:6846
Homologene: 55686
Fbxo22
Name: F-box protein 22
Synonyms: 1600016C16Rik, 0610033L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71999
Homologene: 12433
Usp47
Name: ubiquitin specific peptidase 47
Synonyms: 4930502N04Rik, A630020C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74996
Homologene: 9929
Sephs1
Name: selenophosphate synthetase 1
Synonyms: SPS1, 1110046B24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 109079
Homologene: 56558
Dock6
Name: dedicator of cytokinesis 6
Synonyms: 2410095B20Rik, 4931431C02Rik, C330023D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319899
VEGA: 9
Homologene: 83291
Sap30bp
Name: SAP30 binding protein
Synonyms: 2700016D05Rik, Hcngp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57230
Homologene: 8308
Suco
Name: SUN domain containing ossification factor
Synonyms: osteopotentia, Opt, AI848100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226551
HGNC: HGNC:1240
Homologene: 32212
Gtf3c1
Name: general transcription factor III C 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233863
HGNC: HGNC:4664
Homologene: 31040
Fer
Name: fer (fms/fps related) protein kinase
Synonyms: Fert, C330004K01Rik, Fert2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14158
VEGA: 17
HGNC: HGNC:3655
Homologene: 74300
Ets2
Name: E26 avian leukemia oncogene 2, 3' domain
Synonyms: Ets-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 23872
HGNC: HGNC:3489
Homologene: 3838
Sspn
Name: sarcospan
Synonyms: Krag
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16651
Homologene: 3727
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: 5730509K17Rik, b2b1035Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231214
Homologene: 18159
Wdr62
Name: WD repeat domain 62
Synonyms: 2310038K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233064
Homologene: 15927
Adcy4
Name: adenylate cyclase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 104110
VEGA: 14
HGNC: HGNC:235
Homologene: 23149
Zfp592
Name: zinc finger protein 592
Synonyms: A730014M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233410
Homologene: 8759
Uimc1
Name: ubiquitin interaction motif containing 1
Synonyms: D630032M02Rik, D330018D10Rik, 9430016E08Rik, Rxrip110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20184
Homologene: 9455
Cenpe
Name: centromere protein E
Synonyms: N-7 kinesin, CENP-E, 312kDa, Kif10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Pes1
Name: pescadillo ribosomal biogenesis factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 64934
HGNC: HGNC:8848
Homologene: 5984
Nptx1
Name: neuronal pentraxin 1
Synonyms: Np1, D11Bwg1004e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18164
HGNC: HGNC:7952
Homologene: 1891
Gtf3c2
Name: general transcription factor IIIC, polypeptide 2, beta
Synonyms: 2610510G03Rik, TFIIIC-BETA, TFIIIC110, 1300004C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71752
HGNC: HGNC:4665
Homologene: 37490
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Vav1
Name: vav 1 oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22324
Homologene: 3961
Reln
Name: reelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: tigmin, FPC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 4833413O10Rik, D430029O09Rik, 1110021D17Rik, Polydom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64817
Homologene: 23386
Poteg
Name: POTE ankyrin domain family, member G
Synonyms: 4930456F22Rik, 4921537P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 70952
Homologene: 134158
Cntn1
Name: contactin 1
Synonyms: CNTN, F3cam, usl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12805
HGNC: HGNC:2171
Homologene: 7274
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Ighg2c
Name: immunoglobulin heavy constant gamma 2C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 404711
Zcchc4
Name: zinc finger, CCHC domain containing 4
Synonyms: 4930449I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 78796
Homologene: 14632
Myom2
Name: myomesin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17930
HGNC: HGNC:7614
Homologene: 2953
Crybg2
Name: crystallin beta-gamma domain containing 2
Synonyms: Aim1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230806
Homologene: 19232
Vmn1r68
Name: vomeronasal 1 receptor 68
Synonyms: Gm6898
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628580
Homologene: 120153
Sipa1l2
Name: signal-induced proliferation-associated 1 like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244668
Homologene: 18956
Meikin
Name: meiotic kinetochore factor
Synonyms: 4930404A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74847
Homologene: 54900
Ripk3
Name: receptor-interacting serine-threonine kinase 3
Synonyms: Rip3, 2610528K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56532
VEGA: 14
Homologene: 31410
Smg8
Name: smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
Synonyms: 1200011M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74133
Homologene: 32393
Lrmp
Name: lymphoid-restricted membrane protein
Synonyms: Jaw1, D6Int7, D6Int8, D6Int5, D6Int4, D6Int3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16970
HGNC: HGNC:6690
Homologene: 4483
Olfr1182
Name: olfactory receptor 1182
Synonyms: GA_x6K02T2Q125-49934557-49933640, MOR225-8P, MOR225-7P, MOR225-16_p, MOR225-8P, Olfr1536-ps1, Gm13757
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258167
Homologene: 86666
Hs6st3
Name: heparan sulfate 6-O-sulfotransferase 3
Synonyms: 6OST3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50787
VEGA: 14
Homologene: 89201
Mrc2
Name: mannose receptor, C type 2
Synonyms: novel lectin, Endo180, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17534
Homologene: 4408
Adam21
Name: a disintegrin and metallopeptidase domain 21
Synonyms: ADAM31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56622
HGNC: HGNC:200
Homologene: 68365
Mgst1
Name: microsomal glutathione S-transferase 1
Synonyms: 1500002K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56615
HGNC: HGNC:7061
Homologene: 10544
Zfp326
Name: zinc finger protein 326
Synonyms: ZAN75, 5730470H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54367
Homologene: 10297
C1ra
Name: complement component 1, r subcomponent A
Synonyms: mC1rA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 50909
HGNC: HGNC:1246
Homologene: 1313
Olfr490
Name: olfactory receptor 490
Synonyms: GA_x6K02T2PBJ9-10617173-10616229, MOR204-17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258491
Homologene: 73955
Rassf5
Name: Ras association (RalGDS/AF-6) domain family member 5
Synonyms: 1300019G20Rik, Nore1B, Nore1A, Rapl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54354
Homologene: 10296
Negr1
Name: neuronal growth regulator 1
Synonyms: Ntra, 5330422G01Rik, neurotractin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320840
Homologene: 41447
Olfr530
Name: olfactory receptor 530
Synonyms: GA_x6K02T2PBJ9-42523824-42522901, MOR252-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258512
Homologene: 128384
Creb3l2
Name: cAMP responsive element binding protein 3-like 2
Synonyms: BBF2H7, C530025K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 208647
Homologene: 18690
Pramel29
Name: PRAME like 29
Synonyms: C87977
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 97187
Homologene: 103830
Gm9774
Name: predicted pseudogene 9774
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100043022
Atp13a2
Name: ATPase type 13A2
Synonyms: 1110012E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74772
Homologene: 56940
Upk3b
Name: uroplakin 3B
Synonyms: PMS2L14, UpIIIb, P35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100647
Homologene: 18435
Trbv21
Name: T cell receptor beta, variable 21
Synonyms: Gm16778, Tcrb-V19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100124686
AC153855.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Sirt7
Name: sirtuin 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 209011
Homologene: 56152
Rhot2
Name: ras homolog family member T2
Synonyms: Miro2, Arht2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 214952
Homologene: 56038
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 20,117,474 bp
  • T to C, chromosome 1 at 131,244,956 bp
  • A to G, chromosome 1 at 161,838,804 bp
  • A to G, chromosome 2 at 4,899,560 bp
  • A to T, chromosome 2 at 88,446,617 bp
  • C to T, chromosome 3 at 92,428,809 bp
  • T to C, chromosome 3 at 135,246,827 bp
  • A to G, chromosome 3 at 157,016,266 bp
  • C to T, chromosome 4 at 58,070,661 bp
  • G to A, chromosome 4 at 134,075,304 bp
  • T to C, chromosome 4 at 141,006,929 bp
  • A to G, chromosome 4 at 144,209,340 bp
  • A to T, chromosome 5 at 22,018,869 bp
  • G to A, chromosome 5 at 31,159,806 bp
  • A to C, chromosome 5 at 43,681,381 bp
  • C to T, chromosome 5 at 52,783,208 bp
  • T to A, chromosome 5 at 105,886,203 bp
  • A to G, chromosome 5 at 136,040,076 bp
  • A to T, chromosome 6 at 37,334,348 bp
  • T to A, chromosome 6 at 41,203,050 bp
  • A to T, chromosome 6 at 70,406,779 bp
  • G to A, chromosome 6 at 124,517,505 bp
  • A to T, chromosome 6 at 138,156,331 bp
  • A to T, chromosome 6 at 145,174,628 bp
  • G to A, chromosome 6 at 145,961,151 bp
  • A to G, chromosome 7 at 10,527,235 bp
  • A to G, chromosome 7 at 30,270,174 bp
  • A to G, chromosome 7 at 81,038,071 bp
  • T to C, chromosome 7 at 108,286,296 bp
  • A to G, chromosome 7 at 112,108,655 bp
  • A to T, chromosome 7 at 125,657,477 bp
  • A to T, chromosome 7 at 140,373,397 bp
  • C to A, chromosome 8 at 15,119,216 bp
  • A to T, chromosome 8 at 16,226,391 bp
  • G to A, chromosome 8 at 27,473,587 bp
  • A to T, chromosome 8 at 125,422,624 bp
  • G to A, chromosome 9 at 21,841,527 bp
  • A to T, chromosome 9 at 55,214,960 bp
  • C to T, chromosome 11 at 3,977,794 bp
  • T to G, chromosome 11 at 3,977,795 bp
  • A to G, chromosome 11 at 9,314,491 bp
  • T to A, chromosome 11 at 54,390,483 bp
  • T to C, chromosome 11 at 87,086,108 bp
  • G to A, chromosome 11 at 105,347,692 bp
  • C to T, chromosome 11 at 110,494,343 bp
  • A to G, chromosome 11 at 112,784,942 bp
  • T to C, chromosome 11 at 115,957,403 bp
  • T to C, chromosome 11 at 119,543,301 bp
  • T to C, chromosome 11 at 120,622,129 bp
  • C to A, chromosome 12 at 81,560,352 bp
  • T to G, chromosome 12 at 113,287,964 bp
  • C to T, chromosome 13 at 55,060,266 bp
  • A to C, chromosome 13 at 68,727,945 bp
  • T to C, chromosome 14 at 55,781,597 bp
  • G to T, chromosome 14 at 55,788,391 bp
  • T to A, chromosome 14 at 119,869,062 bp
  • A to T, chromosome 15 at 92,314,563 bp
  • G to A, chromosome 16 at 95,716,156 bp
  • G to A, chromosome 17 at 25,842,028 bp
  • A to T, chromosome 17 at 57,303,862 bp
  • C to T, chromosome 17 at 64,035,508 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0634 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038823-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.