Strain Name:
C57BL/6J-MtgxR0829Btlr/Mmmh
Stock Number:
039009-MU
Citation ID:
RRID:MMRRC_039009-MU
Other Names:
R0829 (G1), C57BL/6J-MtgxR0829Btlr
Major Collection:

Gene Information

Mitf
Name: melanogenesis associated transcription factor
Synonyms: mi, wh, BCC2, bHLHe32, Gsfbcc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17342
HGNC: HGNC:7105
Homologene: 4892
Tert
Name: telomerase reverse transcriptase
Synonyms: TR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21752
VEGA: 13
Homologene: 31141
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Rbm25
Name: RNA binding motif protein 25
Synonyms: 2610015J01Rik, A130095G20Rik, 2600011C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 67039
Srebf2
Name: sterol regulatory element binding factor 2
Synonyms: SREBP-2, nuc, SREBP2, SREBP2gc, bHLHd2, lop13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20788
VEGA: 15
Homologene: 20966
Nomo1
Name: nodal modulator 1
Synonyms: PM5, Nomo, D7Ertd156e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 211548
Homologene: 13810
Usp19
Name: ubiquitin specific peptidase 19
Synonyms: 8430421I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71472
Homologene: 41730
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: LOC381341, Dnahc7, Dnahc7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 627872
Homologene: 41287
Zbtb14
Name: zinc finger and BTB domain containing 14
Synonyms: ZF5, Zfp161, b2b1982Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22666
Homologene: 2560
Gfpt1
Name: glutamine fructose-6-phosphate transaminase 1
Synonyms: GFAT, GFA, GFAT1, 2810423A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14583
HGNC: HGNC:4241
Homologene: 68220
Dnajb6
Name: DnaJ heat shock protein family (Hsp40) member B6
Synonyms: Mrj, mDj4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 23950
Homologene: 38058
Stimate
Name: STIM activating enhancer
Synonyms: 1810038N08Rik, 2310014H19Rik, Tmem110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 69179
Homologene: 7082
Lemd3
Name: LEM domain containing 3
Synonyms: Man1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 380664
Homologene: 8633
Grin1
Name: glutamate receptor, ionotropic, NMDA1 (zeta 1)
Synonyms: NMDAR1, NR1, Nmdar, M100174, GluRzeta1, Rgsc174
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14810
HGNC: HGNC:4584
Homologene: 7187
Cercam
Name: cerebral endothelial cell adhesion molecule
Synonyms: CerCAM, Ceecam1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99151
Homologene: 22954
Lrrc74b
Name: leucine rich repeat containing 74B
Synonyms: 4930451C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74685
Homologene: 25894
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: MyHC-pn, Myhs-p, Myhsp, 4832426G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Olfr213
Name: olfactory receptor 213
Synonyms: GA_x54KRFPKN04-58174409-58175392, MOR119-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258020
Homologene: 74186
Olfr1186
Name: olfactory receptor 1186
Synonyms: GA_x6K02T2Q125-50012960-50013871, MOR230-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258523
Homologene: 110555
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320277
Homologene: 23371
Cpb1
Name: carboxypeptidase B1 (tissue)
Synonyms: 2210008M23Rik, 0910001A18Rik, 1810063F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76703
HGNC: HGNC:2299
Homologene: 68127
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: ojoplano, Opo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218165
VEGA: 13
Homologene: 125376
Scaf11
Name: SR-related CTD-associated factor 11
Synonyms: 1110061H03Rik, SRRP129, CASP11, SIP1, 2610510E10Rik, Sfrs2ip, Srsf2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72193
VEGA: 15
Homologene: 37957
Xkr4
Name: X-linked Kx blood group related 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 497097
Homologene: 45848
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192950
Homologene: 135717
Rasl10b
Name: RAS-like, family 10, member B
Synonyms: VTS58635, B230331P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276952
Homologene: 14108
Itgb5
Name: integrin beta 5
Synonyms: [b]5B, [b]5A, [b]-5, beta-5, beta5, [b]5, ESTM23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16419
HGNC: HGNC:6160
Homologene: 20511
Iqck
Name: IQ motif containing K
Synonyms: A230094G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434232
Homologene: 45162
Atp4b
Name: ATPase, H+/K+ exchanging, beta polypeptide
Synonyms: H+,K+-ATPase, H,K-ATPase-Beta, H+/K+-ATPase beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11945
HGNC: HGNC:820
Homologene: 20182
Potea
Name: POTE ankyrin domain family member A
Synonyms: 4930430A15Rik, A26c3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67575
Homologene: 69410
Plat
Name: plasminogen activator, tissue
Synonyms: t-PA, tPA, D8Ertd2e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18791
HGNC: HGNC:9051
Homologene: 717
Msgn1
Name: mesogenin 1
Synonyms: Msgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56184
VEGA: 12
Homologene: 10466
Ccdc177
Name: coiled-coil domain containing 177
Synonyms: LOC380768, Gm1568
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 380768
VEGA: 12
Homologene: 128326
Olfr724
Name: olfactory receptor 724
Synonyms: GA_x6K02T2PMLR-5645801-5644872, MOR247-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258485
Homologene: 71986
Adprh
Name: ADP-ribosylarginine hydrolase
Synonyms: Arh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11544
VEGA: 16
HGNC: HGNC:269
Homologene: 874
Olfr1496
Name: olfactory receptor 1496
Synonyms: GA_x6K02T2RE5P-4112771-4113718, MOR127-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258991
Homologene: 17458
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 3,671,246 bp
  • A to G, chromosome 1 at 34,163,220 bp
  • T to C, chromosome 1 at 53,504,079 bp
  • C to T, chromosome 2 at 25,298,448 bp
  • G to T, chromosome 2 at 29,871,067 bp
  • A to T, chromosome 2 at 88,526,228 bp
  • G to A, chromosome 2 at 111,198,105 bp
  • C to T, chromosome 3 at 20,251,943 bp
  • T to C, chromosome 5 at 29,785,022 bp
  • T to C, chromosome 6 at 87,053,865 bp
  • A to T, chromosome 6 at 98,003,908 bp
  • A to G, chromosome 6 at 116,541,265 bp
  • A to G, chromosome 7 at 46,076,172 bp
  • T to C, chromosome 7 at 118,899,888 bp
  • T to G, chromosome 8 at 13,390,098 bp
  • A to G, chromosome 8 at 22,772,257 bp
  • T to C, chromosome 9 at 108,493,801 bp
  • T to A, chromosome 10 at 74,502,766 bp
  • T to C, chromosome 10 at 120,979,083 bp
  • C to A, chromosome 11 at 6,601,158 bp
  • C to A, chromosome 11 at 66,005,176 bp
  • C to A, chromosome 11 at 67,283,500 bp
  • G to A, chromosome 11 at 83,417,839 bp
  • C to T, chromosome 12 at 11,208,524 bp
  • T to C, chromosome 12 at 80,759,479 bp
  • T to C, chromosome 12 at 83,660,376 bp
  • C to T, chromosome 13 at 40,208,829 bp
  • T to C, chromosome 13 at 73,644,385 bp
  • C to T, chromosome 14 at 30,862,885 bp
  • C to A, chromosome 14 at 49,961,046 bp
  • T to C, chromosome 15 at 9,687,813 bp
  • T to A, chromosome 15 at 82,177,589 bp
  • T to C, chromosome 15 at 96,418,689 bp
  • A to G, chromosome 16 at 17,558,390 bp
  • A to G, chromosome 16 at 33,944,201 bp
  • C to A, chromosome 16 at 38,445,788 bp
  • C to A, chromosome 17 at 69,388,502 bp
  • T to A, chromosome 19 at 13,781,192 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0829 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039009-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.