Strain Name:
C57BL/6J-MtgxR0881Btlr/Mmmh
Stock Number:
039048-MU
Citation ID:
RRID:MMRRC_039048-MU
Other Names:
R0881 (G1), C57BL/6J-MtgxR0881Btlr
Major Collection:

Gene Information

Ext1
Name: exostosin glycosyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14042
HGNC: HGNC:3512
Homologene: 30957
Itga8
Name: integrin alpha 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241226
HGNC: HGNC:6144
Homologene: 37396
Lars
Name: leucyl-tRNA synthetase
Synonyms: 3110009L02Rik, 2310045K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 107045
VEGA: 18
HGNC: HGNC:6512
Homologene: 7083
Rictor
Name: RPTOR independent companion of MTOR, complex 2
Synonyms: 6030405M08Rik, D530039E11Rik, 4921505C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78757
VEGA: 15
Homologene: 34317
Aasdh
Name: aminoadipate-semialdehyde dehydrogenase
Synonyms: A230062G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231326
Homologene: 71711
Pou5f1
Name: POU domain, class 5, transcription factor 1
Synonyms: Oct4, Oct3/4, Oct-3/4, Otf4, Otf3, Otf3g, Otf3-rs7, Otf-4, Otf-3, Oct-4, Oct-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18999
HGNC: HGNC:9221
Homologene: 8422
Usp47
Name: ubiquitin specific peptidase 47
Synonyms: 4930502N04Rik, A630020C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74996
Homologene: 9929
Bbx
Name: bobby sox HMG box containing
Synonyms: 5730403O13Rik, 5530401J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70508
Homologene: 10634
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Polr1c
Name: polymerase (RNA) I polypeptide C
Synonyms: RPA40, 40kDa, Rpo1-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20016
Homologene: 3586
Klhdc4
Name: kelch domain containing 4
Synonyms: G430025P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234825
Homologene: 69234
Nup98
Name: nucleoporin 98
Synonyms: Nup96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269966
HGNC: HGNC:8068
Homologene: 35472
Zeb1
Name: zinc finger E-box binding homeobox 1
Synonyms: Nil2, [delta]EF1, MEB1, Tcf8, Zfx1a, Tcf18, AREB6, ZEB, Zfhep, 3110032K11Rik, Zfhx1a, Tw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 21417
Homologene: 31779
Atxn2l
Name: ataxin 2-like
Synonyms: A2RP, A2LG, A2D, A2lp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233871
Homologene: 16513
Angel2
Name: angel homolog 2
Synonyms: 5730410O10Rik, 2610307I21Rik, D1Ertd654e, D1Ertd396e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 52477
Homologene: 16932
Polr3c
Name: polymerase (RNA) III (DNA directed) polypeptide C
Synonyms: RPC62, RPC3, 4933407E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74414
Homologene: 38185
Wnt2b
Name: wingless-type MMTV integration site family, member 2B
Synonyms: Wnt13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22414
Homologene: 22526
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Adam27, Dtgn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Cdan1
Name: congenital dyserythropoietic anemia, type I (human)
Synonyms: CDA-I, CDA1, 1500015A01Rik, codanin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68968
HGNC: HGNC:1713
Homologene: 16324
Itln1
Name: intelectin 1 (galactofuranose binding)
Synonyms: IntL, Itln2, mLfR, Itlna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16429
Homologene: 111044
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4921518A06Rik, 4933421G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Rrbp1
Name: ribosome binding protein 1
Synonyms: mRRp0, ES/130, p180, mRRp1.8, mRRp2, mRRp5.4, mRRp10, mRRp16.8, mRRp15b, mRRp15a, mRRp41, mRRp47, 1700087N07Rik, 5730465C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 81910
Homologene: 68138
Med20
Name: mediator complex subunit 20
Synonyms: 1110011O05Rik, 2410115I17Rik, Trfp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56771
Homologene: 3158
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328783
VEGA: 17
Homologene: 18633
Cacna1c
Name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyms: (alpha)1 subunit, Cchl1a1, Cav1.2, L-type Cav1.2, D930026N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12288
HGNC: HGNC:1390
Homologene: 55484
Dennd4a
Name: DENN/MADD domain containing 4A
Synonyms: F730015K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102442
VEGA: 9
Homologene: 55933
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Ptpro
Name: protein tyrosine phosphatase, receptor type, O
Synonyms: D28, PTPROt, PTP-phi, PTP-BK, PTP-U2, GLEPP1, PTP-oc, Ptpn15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Arhgap29
Name: Rho GTPase activating protein 29
Synonyms: 6720461J18Rik, Parg1, C76601, B130017I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214137
Homologene: 3539
Abcc9
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Synonyms: SUR2B, SUR2A, Sur2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Pth1r
Name: parathyroid hormone 1 receptor
Synonyms: PTH-related peptide receptor, PPR, PTH1R, PTH/PTHrP receptor, Pthr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19228
HGNC: HGNC:9608
Homologene: 267
Olfr340
Name: olfactory receptor 340
Synonyms: GA_x6K02T2NLDC-33147742-33148680, MOR136-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258953
Homologene: 74159
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637908
Homologene: 104040
Adam10
Name: a disintegrin and metallopeptidase domain 10
Synonyms: kuz, kuzbanian, 1700031C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11487
HGNC: HGNC:188
Homologene: 865
Tex48
Name: testis expressed 48
Synonyms: 1700018C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75524
Homologene: 87066
Kcna5
Name: potassium voltage-gated channel, shaker-related subfamily, member 5
Synonyms: Kv1.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16493
HGNC: HGNC:6224
Homologene: 1683
Bmp3
Name: bone morphogenetic protein 3
Synonyms: 9530029I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 110075
HGNC: HGNC:1070
Homologene: 927
Gm7647
Name: predicted gene 7647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108169099
B3glct
Name: beta-3-glucosyltransferase
Synonyms: LOC381694, B3galtl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381694
Homologene: 14978
Klhl25
Name: kelch-like 25
Synonyms: 2810402K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207952
Homologene: 32546
Pgm2
Name: phosphoglucomutase 2
Synonyms: Pgm-1, 3230402E02Rik, Pgm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66681
HGNC: HGNC:8906
Homologene: 6693
Piwil2
Name: piwi-like RNA-mediated gene silencing 2
Synonyms: Miwi like, mili
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57746
VEGA: 14
Homologene: 23071
C9
Name: complement component 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12279
HGNC: HGNC:1358
Homologene: 74406
Xirp1
Name: xin actin-binding repeat containing 1
Synonyms: Xin, mXin alpha, Cmya1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22437
VEGA: 9
Homologene: 7998
Steap4
Name: STEAP family member 4
Synonyms: Tiarp, Tnfaip9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 117167
Homologene: 36422
Olfr943
Name: olfactory receptor 943
Synonyms: GA_x6K02T2PVTD-32881408-32882343, MOR171-44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258323
VEGA: 9
Homologene: 110526
Skint1
Name: selection and upkeep of intraepithelial T cells 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 639781
Homologene: 87538
Atp13a2
Name: ATPase type 13A2
Synonyms: 1110012E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74772
Homologene: 56940
Tox2
Name: TOX high mobility group box family member 2
Synonyms: RxHMG1, LOC269389
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269389
Homologene: 13155
Olfr557
Name: olfactory receptor 557
Synonyms: GA_x6K02T2PBJ9-5414934-5415902, MOR18-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258358
Homologene: 123803
Scgb3a2
Name: secretoglobin, family 3A, member 2
Synonyms: UGRP1, LuLeu1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 117158
Homologene: 14274
Opalin
Name: oligodendrocytic myelin paranodal and inner loop protein
Synonyms: Tmp10, Tmem10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226115
VEGA: 19
Homologene: 13237
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 171,533,381 bp
  • G to A, chromosome 1 at 190,937,464 bp
  • C to T, chromosome 2 at 12,262,192 bp
  • T to G, chromosome 2 at 36,453,440 bp
  • C to A, chromosome 2 at 82,986,273 bp
  • A to T, chromosome 2 at 120,720,985 bp
  • T to A, chromosome 2 at 143,953,253 bp
  • T to A, chromosome 2 at 163,321,445 bp
  • A to G, chromosome 3 at 96,723,847 bp
  • A to G, chromosome 3 at 104,953,197 bp
  • A to G, chromosome 3 at 122,014,679 bp
  • A to G, chromosome 4 at 63,611,991 bp
  • G to A, chromosome 4 at 112,028,857 bp
  • T to A, chromosome 4 at 141,003,931 bp
  • A to T, chromosome 5 at 7,980,388 bp
  • A to T, chromosome 5 at 64,093,008 bp
  • G to A, chromosome 5 at 76,876,283 bp
  • T to C, chromosome 5 at 94,962,980 bp
  • A to G, chromosome 5 at 98,872,602 bp
  • T to A, chromosome 5 at 149,739,569 bp
  • C to T, chromosome 6 at 118,612,625 bp
  • T to A, chromosome 6 at 126,534,994 bp
  • T to A, chromosome 6 at 137,443,594 bp
  • T to A, chromosome 6 at 142,646,303 bp
  • T to C, chromosome 7 at 12,600,932 bp
  • A to G, chromosome 7 at 75,866,279 bp
  • T to A, chromosome 7 at 102,160,716 bp
  • T to A, chromosome 7 at 102,699,084 bp
  • T to A, chromosome 7 at 112,091,436 bp
  • A to G, chromosome 7 at 126,496,596 bp
  • A to T, chromosome 8 at 24,672,143 bp
  • A to T, chromosome 8 at 121,799,487 bp
  • A to G, chromosome 9 at 39,184,688 bp
  • T to C, chromosome 9 at 64,851,383 bp
  • T to C, chromosome 9 at 70,746,237 bp
  • C to T, chromosome 9 at 110,731,573 bp
  • T to C, chromosome 9 at 120,018,417 bp
  • A to C, chromosome 14 at 70,408,927 bp
  • T to C, chromosome 14 at 103,220,013 bp
  • G to A, chromosome 15 at 6,458,868 bp
  • A to T, chromosome 15 at 6,791,670 bp
  • A to C, chromosome 15 at 8,307,612 bp
  • A to G, chromosome 15 at 53,344,483 bp
  • A to G, chromosome 16 at 50,220,600 bp
  • A to T, chromosome 17 at 25,742,965 bp
  • C to T, chromosome 17 at 35,510,279 bp
  • T to C, chromosome 17 at 46,244,613 bp
  • T to C, chromosome 17 at 47,611,680 bp
  • T to C, chromosome 18 at 5,767,138 bp
  • C to T, chromosome 18 at 42,214,786 bp
  • T to G, chromosome 18 at 43,764,484 bp
  • T to C, chromosome 19 at 41,063,981 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0881 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039048-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.