Strain Name:
C57BL/6J-MtgxR0891Btlr/Mmmh
Stock Number:
039054-MU
Citation ID:
RRID:MMRRC_039054-MU
Other Names:
R0891 (G1), C57BL/6J-MtgxR0891Btlr
Major Collection:

Gene Information

Pip5k1a
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
Synonyms: Pipk5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18720
HGNC: HGNC:8994
Homologene: 93492
Pik3r1
Name: phosphoinositide-3-kinase regulatory subunit 1
Synonyms: p85alpha, p50alpha, p55alpha, PI3K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18708
HGNC: HGNC:8979
Homologene: 7889
Arhgap12
Name: Rho GTPase activating protein 12
Synonyms: 2810011M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 75415
Homologene: 23089
Nup93
Name: nucleoporin 93
Synonyms: 2410008G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71805
Homologene: 40971
Ccnf
Name: cyclin F
Synonyms: CycF, Fbxo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12449
VEGA: 17
HGNC: HGNC:1591
Homologene: 1335
Lrrfip1
Name: leucine rich repeat (in FLII) interacting protein 1
Synonyms: FLAP (FLI LRR associated protein), Fliiap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16978
HGNC: HGNC:6702
Homologene: 48301
Angel2
Name: angel homolog 2
Synonyms: 5730410O10Rik, 2610307I21Rik, D1Ertd654e, D1Ertd396e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 52477
Homologene: 16932
Afap1
Name: actin filament associated protein 1
Synonyms: 9630044L16Rik, 2600003E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70292
Homologene: 11009
4930522L14Rik
Name: RIKEN cDNA 4930522L14 gene
Synonyms: Gm42152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100041734
Zfp57
Name: zinc finger protein 57
Synonyms: G19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22715
Homologene: 7603
Mbip
Name: MAP3K12 binding inhibitory protein 1
Synonyms: 4933408E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217588
VEGA: 12
Homologene: 9576
Nipal3
Name: NIPA-like domain containing 3
Synonyms: 9130020G22Rik, Npal3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74552
Homologene: 10722
Septin5
Name: septin 5
Synonyms: Cdcrel1, Pnutl1, Sept5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 18951
VEGA: 16
HGNC: HGNC:9164
Homologene: 74446
Cpne5
Name: copine V
Synonyms: A830083G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240058
HGNC: HGNC:2318
Homologene: 23266
Pigo
Name: phosphatidylinositol glycan anchor biosynthesis, class O
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56703
Homologene: 31761
Col27a1
Name: collagen, type XXVII, alpha 1
Synonyms: 5730512J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 373864
Homologene: 69400
Gen1
Name: GEN1, Holliday junction 5' flap endonuclease
Synonyms: 5830483C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 209334
VEGA: 12
Homologene: 35313
9930021J03Rik
Name: RIKEN cDNA 9930021J03 gene
Synonyms: Gm9832
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240613
Homologene: 19046
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546981
Homologene: 115466
Ankrd36
Name: ankyrin repeat domain 36
Synonyms: 1700012M14Rik, GC3, 1700008J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76389
Homologene: 137366
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: C430014K11Rik, Mll4, Mll2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Semp2l1
Name: SUMO/sentrin specific peptidase 2-like 1
Synonyms: Gm5415
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 408191
Homologene: 130042
Smarcal1
Name: SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Synonyms: Mharp, 6030401P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54380
Homologene: 8558
Pgbd1
Name: piggyBac transposable element derived 1
Synonyms: 4921509E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319207
Homologene: 130030
Fndc7
Name: fibronectin type III domain containing 7
Synonyms: E230011A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320181
Homologene: 18551
Olfr1347
Name: olfactory receptor 1347
Synonyms: GA_x6K02T2QGBW-3218686-3217748, MOR103-19_i, MOR103-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258383
Homologene: 128065
Kcnh8
Name: potassium voltage-gated channel, subfamily H (eag-related), member 8
Synonyms: Kv12.1, ELK1, C130090D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 211468
Homologene: 14332
Ano3
Name: anoctamin 3
Synonyms: B230324K02Rik, Tmem16c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228432
Homologene: 57147
Olfr524
Name: olfactory receptor 524
Synonyms: GA_x6K02T2PBJ9-42354580-42353624, MOR103-14P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258055
Homologene: 79347
Togaram1
Name: TOG array regulator of axonemal microtubules 1
Synonyms: A430041B07Rik, Fam179b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328108
VEGA: 12
Homologene: 15025
Brsk1
Name: BR serine/threonine kinase 1
Synonyms: LOC381979, SAD-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381979
Homologene: 57169
Dcst1
Name: DC-STAMP domain containing 1
Synonyms: A330106H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77772
Homologene: 14981
Ankrd45
Name: ankyrin repeat domain 45
Synonyms: 4933409K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 73844
Homologene: 19617
Calml3
Name: calmodulin-like 3
Synonyms: 2310068O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 70405
VEGA: 13
HGNC: HGNC:1452
Homologene: 133078
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 32,546,361 bp
  • T to C, chromosome 1 at 72,598,856 bp
  • T to A, chromosome 1 at 91,068,615 bp
  • A to G, chromosome 1 at 161,155,336 bp
  • G to T, chromosome 1 at 190,945,073 bp
  • T to C, chromosome 2 at 110,697,976 bp
  • G to A, chromosome 3 at 89,353,277 bp
  • A to G, chromosome 3 at 95,065,520 bp
  • A to G, chromosome 3 at 108,870,588 bp
  • G to A, chromosome 4 at 43,020,519 bp
  • A to C, chromosome 4 at 63,305,183 bp
  • A to T, chromosome 4 at 135,468,587 bp
  • G to A, chromosome 5 at 35,961,852 bp
  • A to T, chromosome 5 at 109,736,290 bp
  • A to G, chromosome 7 at 4,704,227 bp
  • T to A, chromosome 7 at 6,488,472 bp
  • A to T, chromosome 7 at 86,164,268 bp
  • A to G, chromosome 7 at 140,202,459 bp
  • T to A, chromosome 8 at 94,281,263 bp
  • A to G, chromosome 11 at 5,687,316 bp
  • A to G, chromosome 12 at 11,248,354 bp
  • A to T, chromosome 12 at 56,340,457 bp
  • A to G, chromosome 12 at 64,982,647 bp
  • A to G, chromosome 13 at 3,803,926 bp
  • T to C, chromosome 13 at 21,422,800 bp
  • A to T, chromosome 13 at 101,701,466 bp
  • A to G, chromosome 15 at 98,852,691 bp
  • G to C, chromosome 16 at 18,624,845 bp
  • G to T, chromosome 17 at 24,226,777 bp
  • A to G, chromosome 17 at 29,202,919 bp
  • A to G, chromosome 17 at 37,006,176 bp
  • A to T, chromosome 17 at 52,905,214 bp
  • T to C, chromosome 18 at 6,026,699 bp
  • G to A, chromosome 19 at 29,717,653 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0891 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039054-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.