Strain Name:
C57BL/6J-MtgxR1055Btlr/Mmmh
Stock Number:
039145-MU
Citation ID:
RRID:MMRRC_039145-MU
Other Names:
R1055 (G1), C57BL/6J-MtgxR1055Btlr
Major Collection:

Gene Information

Dnmt3a
Name: DNA methyltransferase 3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13435
HGNC: HGNC:2978
Homologene: 7294
Srd5a3
Name: steroid 5 alpha-reductase 3
Synonyms: Srd5a2l, D730040M03Rik, 1110025P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57357
Homologene: 41385
Ilrun
Name: inflammation and lipid regulator with UBA-like and NBR1-like domains
Synonyms: D17Wsu92e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224647
Homologene: 32575
Gtf2i
Name: general transcription factor II I
Synonyms: BAP-135, TFII-I, 6030441I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14886
HGNC: HGNC:4659
Homologene: 7748
Rpa1
Name: replication protein A1
Synonyms: 5031405K23Rik, RP-A, 70kDa, RF-A, Rpa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68275
Homologene: 2208
Zfand6
Name: zinc finger, AN1-type domain 6
Synonyms: 3110005P07Rik, Za20d3, Awp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 65098
Homologene: 10372
Gfpt2
Name: glutamine fructose-6-phosphate transaminase 2
Synonyms: GFAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14584
HGNC: HGNC:4242
Homologene: 68439
Pard3
Name: par-3 family cell polarity regulator
Synonyms: ASIP, Par3, PAR-3, D8Ertd580e, Pard3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 93742
Homologene: 10489
Ahctf1
Name: AT hook containing transcription factor 1
Synonyms: Elys, 6230412P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226747
Homologene: 9142
Zfp280d
Name: zinc finger protein 280D
Synonyms: Suhw4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235469
Homologene: 17151
Rabgap1
Name: RAB GTPase activating protein 1
Synonyms: Gapcena
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227800
Homologene: 49301
Myo9a
Name: myosin IXa
Synonyms: C130068I12Rik, 4732465J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Dcdc2a
Name: doublecortin domain containing 2a
Synonyms: Dcdc2, RU2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 195208
Homologene: 9483
Adcy1
Name: adenylate cyclase 1
Synonyms: D11Bwg1392e, I-AC, AC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432530
HGNC: HGNC:232
Homologene: 41419
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Csn2
Name: casein beta
Synonyms: Csnb, CSN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12991
HGNC: HGNC:2447
Homologene: 1426
Pomt2
Name: protein-O-mannosyltransferase 2
Synonyms: A830009D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217734
VEGA: 12
Homologene: 5297
Marchf11
Name: membrane associated ring-CH-type finger 11
Synonyms: March11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 211147
Homologene: 45584
Tmprss2
Name: transmembrane protease, serine 2
Synonyms: epitheliasin, D16Ertd61e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 50528
VEGA: 16
Homologene: 4136
Nptxr
Name: neuronal pentraxin receptor
Synonyms: NPCD, 5730406O18Rik, NPR, D15Bwg0580e, 1700036C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 73340
HGNC: HGNC:7954
Homologene: 8620
Ebf1
Name: early B cell factor 1
Synonyms: Olf1, O/E-1, Olf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13591
HGNC: HGNC:3126
Homologene: 7297
Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Synonyms: Nav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20265
Homologene: 21375
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Sall3
Name: spalt like transcription factor 3
Synonyms: Salt, B130022O04Rik, Msal, Msal-1, Spalt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 20689
VEGA: 18
Homologene: 18142
Hsh2d
Name: hematopoietic SH2 domain containing
Synonyms: Hsh2, ALX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209488
Homologene: 13142
Chia1
Name: chitinase, acidic 1
Synonyms: AMCase, 2200003E03Rik, YNL, Chia
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 81600
Homologene: 75168
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 4632412F08Rik, 5330435L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237979
Homologene: 10406
Hoxc11
Name: homeobox C11
Synonyms: Hox-3.7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 109663
HGNC: HGNC:5123
Homologene: 130362
Clrn1
Name: clarin 1
Synonyms: clarin-1, USH3, A130002D11Rik, Ush3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229320
Homologene: 17738
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Cd244a
Name: CD244 molecule A
Synonyms: Nmrk, F730046O15Rik, 2B4, Cd244, C9.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18106
Homologene: 9493
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Khdrbs2
Name: KH domain containing, RNA binding, signal transduction associated 2
Synonyms: 6330586C16Rik, SLM-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 170771
Homologene: 15772
Nrp1
Name: neuropilin 1
Synonyms: NP-1, Npn1, NPN-1, Neuropilin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18186
HGNC: HGNC:8004
Homologene: 2876
Nhsl1
Name: NHS-like 1
Synonyms: D10Bwg0940e, A630035H13Rik, 5730409E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215819
Homologene: 27834
Arhgef11
Name: Rho guanine nucleotide exchange factor (GEF) 11
Synonyms: PDZ-RhoGEF, Prg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213498
Homologene: 11409
AC145553.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 268527
Homologene: 8780
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218165
VEGA: 13
Homologene: 125376
Shpk
Name: sedoheptulokinase
Synonyms: 4930431K22Rik, Carkl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74637
HGNC: HGNC:1492
Homologene: 8319
Ugt1a6a
Name: UDP glucuronosyltransferase 1 family, polypeptide A6A
Synonyms: UGT1.6, Ugt1a6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 94284
Homologene: 85959
Slc34a1
Name: solute carrier family 34 (sodium phosphate), member 1
Synonyms: renal Na+/Pi transporter, NaPi-IIa, Slc17a2, Npt2, Na/Pi cotransporter
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20505
VEGA: 13
Homologene: 20663
Sdr42e1
Name: short chain dehydrogenase/reductase family 42E, member 1
Synonyms: 4632417N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74032
Homologene: 23654
Wiz
Name: widely-interspaced zinc finger motifs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22404
Homologene: 7997
Olfr1126
Name: olfactory receptor 1126
Synonyms: GA_x6K02T2Q125-48959068-48960012, MOR264-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258834
Homologene: 133659
Adcy7
Name: adenylate cyclase 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11513
HGNC: HGNC:238
Homologene: 866
A1cf
Name: APOBEC1 complementation factor
Synonyms: 1810073H04Rik, apobec-1 complementation factor, ACF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69865
VEGA: 19
Homologene: 16363
4930578I06Rik
Name: RIKEN cDNA 4930578I06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67750
VEGA: 14
Homologene: 49859
Uap1
Name: UDP-N-acetylglucosamine pyrophosphorylase 1
Synonyms: ESTM38, AgX, AGX1, SPAG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 107652
Homologene: 2342
Actl10
Name: actin-like 10
Synonyms: 1700007I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70362
Homologene: 128516
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625109
Homologene: 129606
Lrrc23
Name: leucine rich repeat containing 23
Synonyms: 4921537K05Rik, Lrpb7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16977
Homologene: 5082
Gpank1
Name: G patch domain and ankyrin repeats 1
Synonyms: Bat4, D17H6S54E, G5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81845
Homologene: 13035
Qsox2
Name: quiescin Q6 sulfhydryl oxidase 2
Synonyms: Qscn6l1, QSOX2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227638
Homologene: 65608
Olfr1469
Name: olfactory receptor 1469
Synonyms: GA_x6K02T2RE5P-3743369-3744289, MOR202-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258690
HGNC: HGNC:8324
Homologene: 133675
Lix1l
Name: Lix1-like
Synonyms: D130027M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 280411
Homologene: 16014
Vmn2r32
Name: vomeronasal 2, receptor 32
Synonyms: V2r5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22311
Homologene: 113703
AC139244.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Clpsl2
Name: colipase-like 2
Synonyms: LOC328788, Gm749
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328788
Homologene: 86835
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 32,644,157 bp
  • A to G, chromosome 1 at 88,139,014 bp
  • G to T, chromosome 1 at 170,156,911 bp
  • T to A, chromosome 1 at 171,577,276 bp
  • G to A, chromosome 1 at 179,763,486 bp
  • A to G, chromosome 2 at 26,214,125 bp
  • A to G, chromosome 2 at 37,492,068 bp
  • T to C, chromosome 2 at 66,337,996 bp
  • ATTGCTACTC to A, chromosome 2 at 87,457,437 bp
  • A to T, chromosome 2 at 154,552,668 bp
  • T to A, chromosome 3 at 58,865,110 bp
  • A to C, chromosome 3 at 87,717,118 bp
  • G to T, chromosome 3 at 96,621,310 bp
  • A to C, chromosome 3 at 106,130,883 bp
  • A to G, chromosome 5 at 76,153,638 bp
  • G to A, chromosome 5 at 87,694,737 bp
  • A to T, chromosome 5 at 134,263,624 bp
  • T to C, chromosome 6 at 124,778,151 bp
  • C to T, chromosome 7 at 7,474,327 bp
  • G to T, chromosome 7 at 33,287,343 bp
  • A to G, chromosome 7 at 84,615,973 bp
  • G to A, chromosome 8 at 72,200,460 bp
  • T to C, chromosome 8 at 88,318,057 bp
  • T to G, chromosome 8 at 117,663,584 bp
  • T to C, chromosome 8 at 127,378,280 bp
  • A to G, chromosome 8 at 128,468,598 bp
  • A to T, chromosome 9 at 59,855,370 bp
  • G to A, chromosome 9 at 72,329,167 bp
  • T to A, chromosome 10 at 18,525,475 bp
  • T to A, chromosome 10 at 130,446,357 bp
  • T to C, chromosome 11 at 7,109,075 bp
  • A to G, chromosome 11 at 44,632,775 bp
  • A to C, chromosome 11 at 49,827,211 bp
  • A to T, chromosome 11 at 66,160,011 bp
  • A to T, chromosome 11 at 73,215,119 bp
  • A to T, chromosome 11 at 75,302,732 bp
  • C to T, chromosome 11 at 113,838,646 bp
  • T to A, chromosome 12 at 3,872,864 bp
  • G to A, chromosome 12 at 7,994,963 bp
  • T to C, chromosome 12 at 16,682,251 bp
  • C to T, chromosome 12 at 52,880,672 bp
  • G to A, chromosome 12 at 87,147,480 bp
  • T to A, chromosome 13 at 25,102,610 bp
  • C to T, chromosome 13 at 40,208,829 bp
  • G to T, chromosome 13 at 55,403,033 bp
  • A to G, chromosome 14 at 63,973,275 bp
  • A to T, chromosome 15 at 26,309,662 bp
  • A to G, chromosome 15 at 47,881,537 bp
  • T to C, chromosome 15 at 79,790,255 bp
  • T to A, chromosome 15 at 102,954,835 bp
  • C to A, chromosome 16 at 32,806,718 bp
  • T to C, chromosome 16 at 97,576,262 bp
  • T to C, chromosome 17 at 27,767,936 bp
  • C to T, chromosome 17 at 28,549,526 bp
  • A to G, chromosome 17 at 32,387,642 bp
  • T to A, chromosome 17 at 35,124,308 bp
  • A to C, chromosome 18 at 80,969,792 bp
  • G to A, chromosome 19 at 13,411,390 bp
  • C to A, chromosome 19 at 31,932,519 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1055 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039145-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.