Strain Name:
C57BL/6J-MtgxR1117Btlr/Mmmh
Stock Number:
039190-MU
Citation ID:
RRID:MMRRC_039190-MU
Other Names:
R1117 (G1), C57BL/6J-MtgxR1117Btlr
Major Collection:

Gene Information

Sez6
Name: seizure related gene 6
Synonyms: sez-6, D11Bhm177e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20370
Homologene: 10948
Wdr43
Name: WD repeat domain 43
Synonyms: 2610318G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72515
VEGA: 17
Homologene: 38810
Cul3
Name: cullin 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26554
HGNC: HGNC:2553
Homologene: 2661
Slc19a2
Name: solute carrier family 19 (thiamine transporter), member 2
Synonyms: THTR1, DDA1, TRMA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 116914
Homologene: 38258
Gtf3c3
Name: general transcription factor IIIC, polypeptide 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98488
HGNC: HGNC:4666
Homologene: 40805
Casz1
Name: castor zinc finger 1
Synonyms: Cst, D4Ertd432e, 2410019P08Rik, castor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69743
Homologene: 9824
Crispld1
Name: cysteine-rich secretory protein LCCL domain containing 1
Synonyms: Cocoacrisp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 83691
Homologene: 12857
Nid2
Name: nidogen 2
Synonyms: entactin 2, entactin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18074
VEGA: 14
Homologene: 40575
Cntrl
Name: centriolin
Synonyms: 6720467O09Rik, Ma2a8, Cep1, b2b1468Clo, Cep110, IB3/5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26920
HGNC: HGNC:1858
Homologene: 38260
Zfyve19
Name: zinc finger, FYVE domain containing 19
Synonyms: 1500041L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72008
Homologene: 12435
Tcerg1
Name: transcription elongation regulator 1 (CA150)
Synonyms: p144, Taf2s, 2900090C16Rik, ca150, 2410022J09Rik, Fbp28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 56070
Homologene: 4879
Peak1
Name: pseudopodium-enriched atypical kinase 1
Synonyms: 1110049L02Rik, C230081A13Rik, NKF3 kinase family member
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244895
Homologene: 18259
Umod
Name: uromodulin
Synonyms: uromucoid, Tamm-Horsfall glycoprotein, Urehd1, urehr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22242
Homologene: 2522
Cpa1
Name: carboxypeptidase A1, pancreatic
Synonyms: 0910001L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 109697
HGNC: HGNC:2296
Homologene: 55609
Stat4
Name: signal transducer and activator of transcription 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20849
Homologene: 20679
Trim43a
Name: tripartite motif-containing 43A
Synonyms: Gm6021
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 547109
Homologene: 105432
Sel1l3
Name: sel-1 suppressor of lin-12-like 3 (C. elegans)
Synonyms: 2310045A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231238
Homologene: 9054
Tmem132c
Name: transmembrane protein 132C
Synonyms: 4632425D07Rik, 2810482M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208213
Homologene: 76567
Arpc1b
Name: actin related protein 2/3 complex, subunit 1B
Synonyms: SOP2Hs, L72, p41-ARC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11867
HGNC: HGNC:704
Homologene: 4179
Elp4
Name: elongator acetyltransferase complex subunit 4
Synonyms: A330107A17Rik, Paxneb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77766
HGNC: HGNC:1171
Homologene: 32433
Olfr63
Name: olfactory receptor 63
Synonyms: MOR267-1, M4, GA_x6K02T2NTC5-9778-8828
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258939
HGNC: HGNC:8174
Homologene: 130665
Mmrn1
Name: multimerin 1
Synonyms: 4921530G03Rik, Emilin4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 70945
HGNC: HGNC:7178
Homologene: 49134
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216188
Homologene: 51942
Etnppl
Name: ethanolamine phosphate phospholyase
Synonyms: Agxt2l1, 1300019H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71760
Homologene: 69440
Gm9573
Name: predicted gene 9573
Synonyms: Muc21, epiglycanin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 672682
AC154271.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Cyp2c68
Name: cytochrome P450, family 2, subfamily c, polypeptide 68
Synonyms: 9030012A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 433247
Homologene: 74936
Fmo4
Name: flavin containing monooxygenase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226564
HGNC: HGNC:3772
Homologene: 68219
Olfr311
Name: olfactory receptor 311
Synonyms: GA_x6K02T2NKPP-565870-564944, MOR222-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258530
Homologene: 77375
Slc36a3
Name: solute carrier family 36 (proton/amino acid symporter), member 3
Synonyms: PAT3, TRAMD2, tramdorin2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 215332
Homologene: 76175
Olfr981
Name: olfactory receptor 981
Synonyms: GA_x6K02T2PVTD-33720892-33721824, MOR223-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258283
VEGA: 9
Homologene: 64849
Klk1b22
Name: kallikrein 1-related peptidase b22
Synonyms: Egfbp1, mGk-22, Egfbp-1, Klk22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13646
HGNC: HGNC:6364
Homologene: 68141
Ccr4
Name: chemokine (C-C motif) receptor 4
Synonyms: CC CKR-4, Cmkbr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12773
VEGA: 9
HGNC: HGNC:1605
Homologene: 21135
Oxct1
Name: 3-oxoacid CoA transferase 1
Synonyms: 2610008O03Rik, Scot-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67041
HGNC: HGNC:8527
Homologene: 377
Kcnj15
Name: potassium inwardly-rectifying channel, subfamily J, member 15
Synonyms: 4930414N08Rik, IRKK, Kir4.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16516
HGNC: HGNC:6261
Homologene: 1690
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 17,749,622 bp
  • T to A, chromosome 1 at 52,013,942 bp
  • C to T, chromosome 1 at 54,417,778 bp
  • T to C, chromosome 1 at 80,280,924 bp
  • A to G, chromosome 1 at 162,803,663 bp
  • A to T, chromosome 1 at 164,263,456 bp
  • A to G, chromosome 2 at 35,127,973 bp
  • T to C, chromosome 2 at 105,842,311 bp
  • G to T, chromosome 2 at 119,215,536 bp
  • A to G, chromosome 3 at 130,634,563 bp
  • C to A, chromosome 4 at 148,934,595 bp
  • T to A, chromosome 5 at 53,172,607 bp
  • C to T, chromosome 5 at 127,554,623 bp
  • T to C, chromosome 5 at 145,125,754 bp
  • A to G, chromosome 6 at 30,645,261 bp
  • T to A, chromosome 6 at 60,976,325 bp
  • A to T, chromosome 7 at 44,116,859 bp
  • T to C, chromosome 7 at 119,477,306 bp
  • T to C, chromosome 9 at 40,022,762 bp
  • G to A, chromosome 9 at 56,258,418 bp
  • T to C, chromosome 9 at 88,844,977 bp
  • C to T, chromosome 9 at 114,492,017 bp
  • G to A, chromosome 10 at 83,508,623 bp
  • T to C, chromosome 11 at 55,146,180 bp
  • A to G, chromosome 11 at 58,841,815 bp
  • A to G, chromosome 11 at 77,974,514 bp
  • A to G, chromosome 13 at 85,127,318 bp
  • A to C, chromosome 14 at 19,763,664 bp
  • T to C, chromosome 15 at 4,057,788 bp
  • G to A, chromosome 16 at 95,295,625 bp
  • C to T, chromosome 17 at 33,268,966 bp
  • T to C, chromosome 17 at 35,620,028 bp
  • A to G, chromosome 17 at 71,616,387 bp
  • A to G, chromosome 18 at 42,574,652 bp
  • G to A, chromosome 19 at 39,712,459 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1117 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039190-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.