Strain Name:
C57BL/6J-MtgxR1199Btlr/Mmmh
Stock Number:
039269-MU
Citation ID:
RRID:MMRRC_039269-MU
Other Names:
R1199 (G1), C57BL/6J-MtgxR1199Btlr
Major Collection:

Gene Information

Camk2a
Name: calcium/calmodulin-dependent protein kinase II alpha
Synonyms: alpha-CaMKII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 12322
VEGA: 18
HGNC: HGNC:1460
Homologene: 56577
Vcan
Name: versican
Synonyms: PG-M, Cspg2, DPEAAE, heart defect, hdf, 5430420N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13003
VEGA: 13
HGNC: HGNC:2464
Homologene: 3228
Sez6
Name: seizure related gene 6
Synonyms: sez-6, D11Bhm177e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20370
VEGA: 11
Homologene: 10948
Gpr37l1
Name: G protein-coupled receptor 37-like 1
Synonyms: CAG-18, D0Kist8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 171469
VEGA: 1
Homologene: 3500
Pomt1
Name: protein-O-mannosyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99011
VEGA: 2
HGNC: HGNC:9202
Homologene: 68548
Lpp
Name: LIM domain containing preferred translocation partner in lipoma
Synonyms: 9430020K16Rik, B130055L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 210126
VEGA: 16
HGNC: HGNC:6679
Homologene: 4075
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: Dhm2, mXrn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 24127
VEGA: 9
Homologene: 5894
Aco2
Name: aconitase 2, mitochondrial
Synonyms: Aco3, Aco-2, D10Wsu183e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 11429
VEGA: 15
HGNC: HGNC:118
Homologene: 856
Agrn
Name: agrin
Synonyms: Agrin, nmf380, NMF380
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11603
VEGA: 4
HGNC: HGNC:329
Homologene: 27907
Srrm2
Name: serine/arginine repetitive matrix 2
Synonyms: 5033413A03Rik, SRm300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 75956
VEGA: 17
Ccdc14
Name: coiled-coil domain containing 14
Synonyms: G630039H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239839
VEGA: 16
Homologene: 32549
Gtf2ird1
Name: general transcription factor II I repeat domain-containing 1
Synonyms: Alb-c-myc line 166.8, binding factor for early enhancer, ESTM9, WBSCR11, c-myc line 166.8, Tg(Alb1-Myc)166.8Sst, Cream1, GTF3, Alb/c-myc line 166.8, BEN, MusTRD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 57080
VEGA: 5
HGNC: HGNC:4661
Homologene: 4158
Btnl9
Name: butyrophilin-like 9
Synonyms: D330012D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237754
VEGA: 11
Homologene: 68540
Amph
Name: amphiphysin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218038
VEGA: 13
HGNC: HGNC:471
Homologene: 121585
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: 2610100B16Rik, Odz3, Ten-m3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 23965
VEGA: 8
Homologene: 22673
Tsc1
Name: TSC complex subunit 1
Synonyms: hamartin, tuberous sclerosis 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 64930
VEGA: 2
Homologene: 314
Deptor
Name: DEP domain containing MTOR-interacting protein
Synonyms: Depdc6, D15Ertd597e, 9130412E02Rik, 4731402B04Rik, D15Ertd336e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 97998
VEGA: 15
Homologene: 32551
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225115
VEGA: 18
Homologene: 25090
Dennd1a
Name: DENN/MADD domain containing 1A
Synonyms: 6030446I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227801
VEGA: 2
Homologene: 17141
Kel
Name: Kell blood group
Synonyms: CD238
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 23925
VEGA: 6
HGNC: HGNC:6308
Homologene: 362
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC1, NBC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54403
VEGA: 5
Homologene: 55776
Cp
Name: ceruloplasmin
Synonyms: D3Ertd555e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12870
VEGA: 3
HGNC: HGNC:2295
Homologene: 75
Pkd2l2
Name: polycystic kidney disease 2-like 2
Synonyms: TRPP5, Polycystin - L2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 53871
VEGA: 18
HGNC: HGNC:9012
Homologene: 22812
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Ttn
Name: titin
Synonyms: D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, mdm, 1100001C23Rik, shru, connectin, L56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
VEGA: 2
Homologene: 130650
Ush2a
Name: usherin
Synonyms: MUSH2A, Ushrn, Ush2a, LOC269160, A930037M10Rik, LOC381317, A930011D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22283
VEGA: 1
Homologene: 66151
Slc46a2
Name: solute carrier family 46, member 2
Synonyms: TSO-1C12, Ly110, Tscot, 5430429N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 30936
VEGA: 4
Homologene: 23273
A1bg
Name: alpha-1-B glycoprotein
Synonyms: C44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 117586
VEGA: 15
HGNC: HGNC:5
Homologene: 11167
Zfp251
Name: zinc finger protein 251
Synonyms: 9130001M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 71591
VEGA: 15
Homologene: 87789
Irs1
Name: insulin receptor substrate 1
Synonyms: G972R, IRS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16367
VEGA: 1
HGNC: HGNC:6125
Homologene: 4049
Stard9
Name: START domain containing 9
Synonyms: 4831403C07Rik, E230025N21Rik, Kif16a, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668880
VEGA: 2
Homologene: 130712
Fgd5
Name: FYVE, RhoGEF and PH domain containing 5
Synonyms: ZFYVE23, C330025N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232237
VEGA: 6
Homologene: 27798
Vmn2r110
Name: vomeronasal 2, receptor 110
Synonyms: EG224582
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224582
Homologene: 129678
Spata6
Name: spermatogenesis associated 6
Synonyms: Hash, 1700062C23Rik, KRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67946
VEGA: 4
Homologene: 10410
Cntn4
Name: contactin 4
Synonyms: Axcam, BIG-2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 269784
VEGA: 6
HGNC: HGNC:2174
Homologene: 14257
Olfr1025-ps1
Name: olfactory receptor 1025, pseudogene 1
Synonyms: MOR196-5P, GA_x6K02T2Q125-47397266-47398205, MOR196-6_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258083
VEGA: 2
Pcnx2
Name: pecanex homolog 2
Synonyms: Pcnxl2, E330039K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270109
VEGA: 8
HGNC: HGNC:8736
Homologene: 8987
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: C230094A16Rik, 2900083P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237711
VEGA: 11
Homologene: 104282
Olfr68
Name: olfactory receptor 68
Synonyms: MOR22-3, GA_x6K02T2PBJ9-6504436-6503489, 3'[b]2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18369
VEGA: 7
Homologene: 130658
Crygn
Name: crystallin, gamma N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 214301
VEGA: 5
Homologene: 16986
Vmn1r60
Name: vomeronasal 1 receptor 60
Synonyms: Gm7184
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 636697
Homologene: 41799
Cpt1b
Name: carnitine palmitoyltransferase 1b, muscle
Synonyms: M-CPTI, M-CPT I, Cpt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12895
VEGA: 15
HGNC: HGNC:2329
Homologene: 22548
Klhdc10
Name: kelch domain containing 10
Synonyms: 2410127E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 76788
VEGA: 6
Homologene: 15267
Samhd1
Name: SAM domain and HD domain, 1
Synonyms: E330031J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56045
VEGA: 2
Homologene: 9160
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 625109
Homologene: 129606
Vmn1r189
Name: vomeronasal 1 receptor 189
Synonyms: V1rh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 252906
VEGA: 13
Homologene: 110880
Kif1c
Name: kinesin family member 1C
Synonyms: D11Bwg1349e, Orch3, B430105J22Rik, N-3 kinsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16562
VEGA: 11
HGNC: HGNC:6317
Homologene: 4821
Pcsk1
Name: proprotein convertase subtilisin/kexin type 1
Synonyms: PC3, SPC3, Phpp-1, Nec-1, PC1, prohormone convertase 1/3, Nec1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18548
VEGA: 13
HGNC: HGNC:8743
Homologene: 379
Mettl27
Name: methyltransferase like 27
Synonyms: Wbscr27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 79565
VEGA: 5
Homologene: 11553
Gm5174
Name: predicted gene 5174
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 382395
VEGA: 10
Homologene: 141143
Slc25a44
Name: solute carrier family 25, member 44
Synonyms: B430110G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229517
VEGA: 3
Homologene: 14000
Fgfbp1
Name: fibroblast growth factor binding protein 1
Synonyms: FGF-BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14181
VEGA: 5
Homologene: 3766
1700102P08Rik
Name: RIKEN cDNA 1700102P08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 112418
VEGA: 9
Homologene: 14230
Ftcd
Name: formiminotransferase cyclodeaminase
Synonyms: glutamate formiminotransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14317
VEGA: 10
HGNC: HGNC:3974
Homologene: 4848
Dnajc28
Name: DnaJ heat shock protein family (Hsp40) member C28
Synonyms: ORF28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 246738
VEGA: 16
HGNC: HGNC:1297
Homologene: 9869
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 82,289,626 bp
  • A to T, chromosome 1 at 135,166,972 bp
  • G to A, chromosome 1 at 188,759,795 bp
  • G to A, chromosome 2 at 28,665,626 bp
  • A to G, chromosome 2 at 32,250,492 bp
  • A to T, chromosome 2 at 37,961,716 bp
  • A to G, chromosome 2 at 76,908,756 bp
  • G to A, chromosome 2 at 76,950,044 bp
  • A to G, chromosome 2 at 85,918,035 bp
  • C to A, chromosome 2 at 120,673,636 bp
  • A to T, chromosome 2 at 157,109,461 bp
  • T to G, chromosome 3 at 19,977,152 bp
  • A to G, chromosome 3 at 88,420,986 bp
  • T to C, chromosome 4 at 59,914,189 bp
  • T to A, chromosome 4 at 111,799,145 bp
  • T to A, chromosome 4 at 156,172,299 bp
  • T to C, chromosome 5 at 24,751,148 bp
  • A to G, chromosome 5 at 43,979,597 bp
  • G to A, chromosome 5 at 89,215,794 bp
  • A to G, chromosome 5 at 134,411,064 bp
  • A to G, chromosome 5 at 134,933,616 bp
  • T to A, chromosome 6 at 30,449,494 bp
  • C to T, chromosome 6 at 41,688,591 bp
  • T to A, chromosome 6 at 91,986,978 bp
  • T to C, chromosome 6 at 106,353,597 bp
  • A to C, chromosome 7 at 5,544,972 bp
  • A to T, chromosome 7 at 103,777,985 bp
  • G to T, chromosome 8 at 48,235,582 bp
  • G to T, chromosome 8 at 125,887,314 bp
  • A to G, chromosome 9 at 95,981,761 bp
  • A to T, chromosome 9 at 108,393,477 bp
  • G to A, chromosome 10 at 76,579,819 bp
  • A to T, chromosome 10 at 86,657,325 bp
  • T to A, chromosome 10 at 130,448,574 bp
  • G to A, chromosome 11 at 29,755,044 bp
  • A to T, chromosome 11 at 49,180,747 bp
  • A to G, chromosome 11 at 70,708,601 bp
  • A to G, chromosome 11 at 77,953,885 bp
  • T to C, chromosome 12 at 52,796,190 bp
  • G to A, chromosome 13 at 19,142,028 bp
  • A to T, chromosome 13 at 22,102,658 bp
  • A to T, chromosome 13 at 75,096,413 bp
  • A to G, chromosome 13 at 89,679,794 bp
  • T to C, chromosome 15 at 55,252,010 bp
  • A to T, chromosome 15 at 60,919,635 bp
  • C to T, chromosome 15 at 76,854,236 bp
  • C to T, chromosome 15 at 81,895,193 bp
  • G to A, chromosome 15 at 89,419,010 bp
  • C to T, chromosome 16 at 24,681,860 bp
  • C to T, chromosome 16 at 34,723,828 bp
  • C to A, chromosome 16 at 91,618,642 bp
  • A to G, chromosome 17 at 20,583,263 bp
  • A to T, chromosome 17 at 23,817,751 bp
  • T to A, chromosome 18 at 5,059,217 bp
  • T to C, chromosome 18 at 34,438,216 bp
  • T to A, chromosome 18 at 60,952,324 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1199 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039269-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.