Strain Name:
C57BL/6J-MtgxR1650Btlr/Mmmh
Stock Number:
039686-MU
Citation ID:
RRID:MMRRC_039686-MU
Other Names:
R1650 (G1), C57BL/6J-MtgxR1650Btlr
Major Collection:

Gene Information

Htr5b
Name: 5-hydroxytryptamine (serotonin) receptor 5B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 15564
Homologene: 74951
Olr1
Name: oxidized low density lipoprotein (lectin-like) receptor 1
Synonyms: SR-EI, Scare1, LOX-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 108078
HGNC: HGNC:8133
Homologene: 1910
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11426
Homologene: 136191
Actn4
Name: actinin alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 60595
HGNC: HGNC:166
Homologene: 55857
Acly
Name: ATP citrate lyase
Synonyms: A730098H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 104112
HGNC: HGNC:115
Homologene: 854
Tyw1
Name: tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Synonyms: Rsafd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100929
Homologene: 7068
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: 1200014O24Rik, Usp52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103135
VEGA: 10
Homologene: 5918
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67074
VEGA: 10
Homologene: 44309
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: skam26Jus, skax26, Cd, ska26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Arl5a
Name: ADP-ribosylation factor-like 5A
Synonyms: Arl5, 2410015N24Rik, 2810410P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75423
HGNC: HGNC:696
Homologene: 100572
Nek1
Name: NIMA (never in mitosis gene a)-related expressed kinase 1
Synonyms: kat, kidney, anemia and testis, D8Ertd790e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18004
HGNC: HGNC:7744
Homologene: 14376
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: Jmjd1b, 5830462I21Rik, JHDM2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Clca2
Name: chloride channel accessory 2
Synonyms: Clca5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229933
HGNC: HGNC:2016
Homologene: 4765
Podxl2
Name: podocalyxin-like 2
Synonyms: PODLX2, Endoglycan, D130074J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 319655
Homologene: 9254
Ppp4r3a
Name: protein phosphatase 4 regulatory subunit 3A
Synonyms: Smek1, 1110034C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68734
VEGA: 12
Homologene: 69510
Zfp592
Name: zinc finger protein 592
Synonyms: A730014M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233410
Homologene: 8759
Rnf165
Name: ring finger protein 165
Synonyms: LOC225743, Ark2c, 2900024M11Rik, G630064H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225743
Homologene: 79757
Shld2
Name: shieldin complex subunit 2
Synonyms: Fam35a, 3110001K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 75698
VEGA: 14
Homologene: 56840
Tle3
Name: transducin-like enhancer of split 3
Synonyms: Grg3a, 2610103N05Rik, Grg3b, ESG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21887
Homologene: 21059
Fgf22
Name: fibroblast growth factor 22
Synonyms: 2210414E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67112
VEGA: 10
HGNC: HGNC:3679
Homologene: 10770
Ctsc
Name: cathepsin C
Synonyms: DPPI, dipeptidylpeptidase 1, DPP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13032
HGNC: HGNC:2528
Homologene: 1373
Itsn2
Name: intersectin 2
Synonyms: Ese2, Eh domain, SH3 domain regulator of endocytosis 2, Sh3d1B, Sh3p18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20403
VEGA: 12
HGNC: HGNC:6184
Homologene: 22627
Ola1
Name: Obg-like ATPase 1
Synonyms: 2810409H07Rik, 2510025G09Rik, 2810405J23Rik, Gtpbp9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67059
Homologene: 5361
Lmbrd1
Name: LMBR1 domain containing 1
Synonyms: 0910001K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68421
Homologene: 10156
Wrnip1
Name: Werner helicase interacting protein 1
Synonyms: 4833444L21Rik, WHIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 78903
Homologene: 10592
Pot1a
Name: protection of telomeres 1A
Synonyms: Pot1, 1500031H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101185
Homologene: 32263
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: Ic, FIC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Nesp2g, nesprin-2, syne-2, dice, Cpfl8, 6820443O06Rik, diminished cone electroretinogram
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319565
Homologene: 56700
Proser3
Name: proline and serine rich 3
Synonyms: BC053749
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 333193
Homologene: 116064
Cyp2c70
Name: cytochrome P450, family 2, subfamily c, polypeptide 70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226105
Homologene: 120027
Sis
Name: sucrase isomaltase (alpha-glucosidase)
Synonyms: sucrase-isomaltase, 2010204N08Rik, Si-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69983
Homologene: 37424
Ccser1
Name: coiled-coil serine rich 1
Synonyms: Fam190a, 6230405M12Rik, C130092O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232035
Homologene: 28086
Strc
Name: stereocilin
Synonyms: DFNB16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 140476
Homologene: 15401
Vmn2r115
Name: vomeronasal 2, receptor 115
Synonyms: V2Rp4, EG638102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 638102
Homologene: 86604
Plekhs1
Name: pleckstrin homology domain containing, family S member 1
Synonyms: 9930023K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226245
VEGA: 19
Homologene: 11770
Dbt
Name: dihydrolipoamide branched chain transacylase E2
Synonyms: D3Wsu60e, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, dihydrolipoyl transacylase, BCKAD E2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 13171
HGNC: HGNC:2698
Homologene: 1444
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22635
Homologene: 124417
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380698
Homologene: 70869
Poteg
Name: POTE ankyrin domain family, member G
Synonyms: 4930456F22Rik, 4921537P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 70952
Homologene: 134158
Unc79
Name: unc-79 homolog
Synonyms: Mlca3, 9030205A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217843
Homologene: 41397
Gm11360
Name: predicted gene 11360
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100041036
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: CMF608, Adlican2, 6530405F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242050
Homologene: 18712
Olfr1280
Name: olfactory receptor 1280
Synonyms: MOR248-1, GA_x6K02T2Q125-72366920-72367837
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258910
Homologene: 121540
Phlpp2
Name: PH domain and leucine rich repeat protein phosphatase 2
Synonyms: C130044A18Rik, Phlppl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244650
Homologene: 71015
Krt84
Name: keratin 84
Synonyms: Krt2-3, Krt2-16, HRb-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16680
VEGA: 15
HGNC: HGNC:6461
Homologene: 22473
1110012J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
Trim28
Name: tripartite motif-containing 28
Synonyms: MommeD9, KRIP-1, Tif1b, KAP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 21849
Homologene: 21175
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Abtb2
Name: ankyrin repeat and BTB (POZ) domain containing 2
Synonyms: BPOZ-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99382
Homologene: 15904
Cdh20
Name: cadherin 20
Synonyms: Cdh7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 23836
HGNC: HGNC:1760
Homologene: 8015
Plin4
Name: perilipin 4
Synonyms: S3-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 57435
Homologene: 69311
Cfhr3
Name: complement factor H-related 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 624286
Homologene: 138664
Dll4
Name: delta like canonical Notch ligand 4
Synonyms: Delta4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 54485
HGNC: HGNC:2910
Homologene: 10411
Pgm1
Name: phosphoglucomutase 1
Synonyms: Pgm1a, 2610020G18Rik, Pgm-2, Pgm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72157
HGNC: HGNC:8905
Homologene: 1979
Lax1
Name: lymphocyte transmembrane adaptor 1
Synonyms: E430019B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240754
Homologene: 49504
Olfr141
Name: olfactory receptor 141
Synonyms: MOR179-5, K17, GA_x6K02T2Q125-48299679-48298702
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257913
Homologene: 28042
Bag4
Name: BCL2-associated athanogene 4
Synonyms: 2410112I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67384
HGNC: HGNC:940
Homologene: 31270
Lca5l
Name: Leber congenital amaurosis 5-like
Synonyms: 4921526F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 385668
HGNC: HGNC:1255
Homologene: 47978
Olfr845
Name: olfactory receptor 845
Synonyms: GA_x6K02T2PVTD-13076685-13077623, Olfr1522-ps1, MOR150-2, MOR150-1P, MOR150-1P, MOR150-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258249
Homologene: 133689
Olfr1366
Name: olfactory receptor 1366
Synonyms: MOR130-2, GA_x6K02T2QHY8-11707053-11707994
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 258280
Homologene: 105872
Olfr1158
Name: olfactory receptor 1158
Synonyms: MOR173-3, GA_x6K02T2Q125-49480812-49481753
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258639
Dyrk4
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
Synonyms: Dyrk4b, Dyrk4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101320
HGNC: HGNC:3095
Homologene: 37858
Ggt5
Name: gamma-glutamyltransferase 5
Synonyms: GGT-REL, Ggtla1, gamma-glutamyl leukotrienase, GGL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 23887
HGNC: HGNC:4260
Homologene: 55802
Cenpn
Name: centromere protein N
Synonyms: 2610510J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72155
Homologene: 12450
Ubox5
Name: U box domain containing 5
Synonyms: UIP5, 1500010O06Rik, C330018L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 140629
Homologene: 8972
Ubqln3
Name: ubiquilin 3
Synonyms: 4933400K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244178
Homologene: 9700
Syce1
Name: synaptonemal complex central element protein 1
Synonyms: 4933406J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74075
Homologene: 77044
Dlg2
Name: discs large MAGUK scaffold protein 2
Synonyms: LOC382816, A330103J02Rik, B230218P12Rik, Gm21505, Dlgh2, B330007M19Rik, PSD93, Chapsyn-110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23859
HGNC: HGNC:2901
Homologene: 1046
Olfr1128
Name: olfactory receptor 1128
Synonyms: GA_x6K02T2Q125-49048592-49047657, MOR176-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258346
Zcchc10
Name: zinc finger, CCHC domain containing 10
Synonyms: D11Ertd416e, 2410141K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67966
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 24,711,558 bp
  • A to T, chromosome 1 at 104,942,230 bp
  • T to A, chromosome 1 at 121,528,162 bp
  • A to G, chromosome 1 at 133,683,992 bp
  • A to G, chromosome 1 at 139,593,826 bp
  • C to A, chromosome 2 at 27,922,159 bp
  • A to T, chromosome 2 at 52,412,105 bp
  • A to T, chromosome 2 at 73,156,894 bp
  • A to T, chromosome 2 at 86,806,747 bp
  • C to A, chromosome 2 at 87,545,428 bp
  • C to T, chromosome 2 at 87,990,801 bp
  • T to G, chromosome 2 at 103,702,402 bp
  • C to T, chromosome 2 at 111,316,295 bp
  • T to C, chromosome 2 at 119,331,130 bp
  • T to C, chromosome 2 at 121,380,885 bp
  • G to A, chromosome 2 at 130,600,425 bp
  • T to C, chromosome 3 at 59,326,162 bp
  • T to A, chromosome 3 at 72,952,418 bp
  • A to G, chromosome 3 at 116,534,732 bp
  • T to A, chromosome 3 at 145,092,212 bp
  • A to G, chromosome 4 at 99,962,070 bp
  • C to A, chromosome 4 at 99,962,079 bp
  • A to T, chromosome 4 at 123,456,600 bp
  • A to G, chromosome 5 at 130,288,911 bp
  • A to T, chromosome 5 at 137,394,601 bp
  • A to T, chromosome 6 at 25,745,965 bp
  • A to G, chromosome 6 at 61,638,490 bp
  • G to A, chromosome 6 at 88,849,919 bp
  • T to C, chromosome 6 at 126,899,829 bp
  • T to A, chromosome 6 at 129,507,089 bp
  • T to C, chromosome 6 at 134,468,769 bp
  • G to A, chromosome 7 at 13,030,849 bp
  • G to A, chromosome 7 at 28,898,266 bp
  • G to A, chromosome 7 at 30,540,326 bp
  • T to A, chromosome 7 at 81,038,100 bp
  • T to A, chromosome 7 at 88,281,426 bp
  • T to C, chromosome 7 at 92,431,051 bp
  • C to T, chromosome 7 at 104,141,021 bp
  • C to A, chromosome 7 at 140,778,387 bp
  • T to A, chromosome 8 at 25,777,424 bp
  • A to G, chromosome 8 at 27,463,785 bp
  • A to T, chromosome 8 at 61,036,076 bp
  • T to C, chromosome 8 at 109,933,955 bp
  • A to G, chromosome 8 at 116,934,759 bp
  • T to G, chromosome 9 at 19,338,647 bp
  • T to C, chromosome 9 at 61,412,253 bp
  • A to G, chromosome 10 at 75,604,761 bp
  • A to T, chromosome 10 at 79,755,189 bp
  • T to C, chromosome 10 at 122,995,777 bp
  • G to A, chromosome 10 at 128,317,899 bp
  • A to T, chromosome 11 at 53,327,402 bp
  • G to T, chromosome 11 at 59,009,678 bp
  • G to A, chromosome 11 at 100,520,367 bp
  • T to A, chromosome 12 at 4,637,767 bp
  • A to T, chromosome 12 at 75,904,259 bp
  • A to T, chromosome 12 at 101,044,619 bp
  • A to G, chromosome 12 at 103,112,793 bp
  • T to C, chromosome 13 at 21,537,079 bp
  • C to T, chromosome 13 at 27,956,396 bp
  • C to A, chromosome 13 at 32,805,379 bp
  • T to A, chromosome 14 at 34,259,617 bp
  • G to A, chromosome 15 at 101,525,963 bp
  • T to C, chromosome 16 at 96,178,940 bp
  • ATCTTCT to ATCT, chromosome 17 at 23,359,988 bp
  • G to A, chromosome 17 at 56,104,931 bp
  • T to A, chromosome 17 at 66,385,876 bp
  • T to C, chromosome 18 at 34,809,115 bp
  • A to G, chromosome 18 at 64,571,549 bp
  • A to C, chromosome 18 at 77,462,417 bp
  • A to G, chromosome 19 at 40,165,477 bp
  • G to T, chromosome 19 at 56,471,042 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1650 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039686-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.