Strain Name:
C57BL/6J-MtgxR2257Btlr/Mmmh
Stock Number:
040257-MU
Citation ID:
RRID:MMRRC_040257-MU
Other Names:
R2257 (G1), C57BL/6J-MtgxR2257Btlr
Major Collection:

Gene Information

Dnajc3
Name: DnaJ heat shock protein family (Hsp40) member C3
Synonyms: Prkri, Dnajc3a, Dnajc3, mp58, Dnajc3b, p58IPK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100037258
VEGA: 14
HGNC: HGNC:9439
Homologene: 2486
Pias3
Name: protein inhibitor of activated STAT 3
Synonyms: Pias3L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229615
Homologene: 4447
Myo1e
Name: myosin IE
Synonyms: 2310020N23Rik, 9130023P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71602
VEGA: 9
HGNC: HGNC:7599
Homologene: 55864
Clasrp
Name: CLK4-associating serine/arginine rich protein
Synonyms: Sfrs16, Srsf16, SWAP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53609
Homologene: 134306
Ppp1r37
Name: protein phosphatase 1, regulatory subunit 37
Synonyms: Lrrc68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232947
Homologene: 17851
Kif4
Name: kinesin family member 4
Synonyms: N-5 kinesin, D330050K22Rik, Kns4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 16571
Homologene: 69022
Nphs1
Name: nephrosis 1, nephrin
Synonyms: nephrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54631
HGNC: HGNC:7908
Homologene: 20974
Fryl
Name: FRY like transcription coactivator
Synonyms: 2510002A14Rik, 9030227G01Rik, 2310004H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72313
Homologene: 103956
Eml4
Name: echinoderm microtubule associated protein like 4
Synonyms: 4930443C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78798
VEGA: 17
HGNC: HGNC:1316
Homologene: 56841
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Numa1
Name: nuclear mitotic apparatus protein 1
Synonyms: NuMA, 6720401E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101706
HGNC: HGNC:8059
Homologene: 38150
Rrp12
Name: ribosomal RNA processing 12 homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107094
VEGA: 19
Homologene: 22370
Copb1
Name: coatomer protein complex, subunit beta 1
Synonyms: Copb1, 2610019B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70349
HGNC: HGNC:2231
Homologene: 5664
Zc3h3
Name: zinc finger CCCH type containing 3
Synonyms: Smicl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223642
VEGA: 15
Homologene: 9029
Thoc1
Name: THO complex 1
Synonyms: NMP-84, 3110002N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225160
VEGA: 18
Homologene: 38012
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: MICAL-3, C130040D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194401
Homologene: 85288
Prrc2a
Name: proline-rich coiled-coil 2A
Synonyms: Bat-2, 3110039B05Rik, D17H6S51E, Bat2, Wbp12, G2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 53761
Homologene: 10567
Arhgap32
Name: Rho GTPase activating protein 32
Synonyms: p200RhoGAP, GC-GAP, PX-RICS, 3426406O18Rik, Grit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330914
Homologene: 8812
Mrps35
Name: mitochondrial ribosomal protein S35
Synonyms: MRPS28, MDSO23, MRP-S28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232536
Homologene: 11048
Rock1
Name: Rho-associated coiled-coil containing protein kinase 1
Synonyms: 1110055K06Rik, Rock-I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19877
VEGA: 18
Homologene: 55899
Ap1s1
Name: adaptor protein complex AP-1, sigma 1
Synonyms: AP19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11769
HGNC: HGNC:559
Homologene: 20342
Psen1
Name: presenilin 1
Synonyms: Ad3h, PS-1, PS1, S182, presenilin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19164
VEGA: 12
HGNC: HGNC:9508
Homologene: 7186
Mgat4a
Name: mannoside acetylglucosaminyltransferase 4, isoenzyme A
Synonyms: 9530018I07Rik, GnT-IVa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269181
HGNC: HGNC:7047
Homologene: 8153
Mybbp1a
Name: MYB binding protein (P160) 1a
Synonyms: p67MBP, p160MBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18432
HGNC: HGNC:7546
Homologene: 40954
Lmo7
Name: LIM domain only 7
Synonyms: LOC380928, FBXO20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Hdc
Name: histidine decarboxylase
Synonyms: Hdc-e, Hdc-a, L-histidine decarboxylase, Hdc-c, Hdc-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15186
HGNC: HGNC:4855
Homologene: 20490
Tmub1
Name: transmembrane and ubiquitin-like domain containing 1
Synonyms: Hops, 2010004O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 64295
Homologene: 11187
Rmdn3
Name: regulator of microtubule dynamics 3
Synonyms: 1200015F23Rik, Fam82a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67809
Homologene: 34926
Fcrls
Name: Fc receptor-like S, scavenger receptor
Synonyms: Msr2, 2810439C17Rik, moFcRH2sc, Fcrh2, IFGP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80891
Homologene: 57117
Ralbp1
Name: ralA binding protein 1
Synonyms: Rip1, RLIP76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19765
VEGA: 17
HGNC: HGNC:9841
Homologene: 4940
Fat1
Name: FAT atypical cadherin 1
Synonyms: Fath, 2310038E12Rik, mFat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Nob1
Name: NIN1/RPN12 binding protein 1 homolog
Synonyms: 1700021I09Rik, ART-4, Nob1p, Psmd8bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67619
Homologene: 31924
Wdr34
Name: WD repeat domain 34
Synonyms: 3200002I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71820
Homologene: 14156
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: D330038K10Rik, 4930543C13Rik, 4930516E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Mctp2
Name: multiple C2 domains, transmembrane 2
Synonyms: LOC244049
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244049
Homologene: 69254
Prss57
Name: protease, serine 57
Synonyms: Prssl1, 2900092M14Rik, UNQ782, GLGL782
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73106
Homologene: 133812
Hgsnat
Name: heparan-alpha-glucosaminide N-acetyltransferase
Synonyms: 9430010M12Rik, D8Ertd354e, Tmem76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 52120
Homologene: 15586
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Tmprss7
Name: transmembrane serine protease 7
Synonyms: matriptase-3, B230219I23Rik, LOC385645
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208171
Homologene: 18178
Dhx36
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 36
Synonyms: 2810407E23Rik, Ddx36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72162
Homologene: 6356
Slco1a6
Name: solute carrier organic anion transporter family, member 1a6
Synonyms: organic anion-transporting polypeptide, Oatp-5, 4930422F19Rik, Slc21a13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 28254
Homologene: 23416
Cyp2b9
Name: cytochrome P450, family 2, subfamily b, polypeptide 9
Synonyms: phenobarbitol inducible, type a, Cyp2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13094
Homologene: 74933
Atp7b
Name: ATPase, Cu++ transporting, beta polypeptide
Synonyms: Wilson protein, WND, Atp7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11979
HGNC: HGNC:870
Homologene: 20063
Cass4
Name: Cas scaffolding protein family member 4
Synonyms: F730031O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320664
Homologene: 75128
Cep162
Name: centrosomal protein 162
Synonyms: 4922501C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382090
Homologene: 8930
Vmn2r59
Name: vomeronasal 2, receptor 59
Synonyms: EG628444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628444
Homologene: 129683
Lrrc6
Name: leucine rich repeat containing 6 (testis)
Synonyms: LRTP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54562
Homologene: 34534
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381157
Homologene: 73393
Sla2
Name: Src-like-adaptor 2
Synonyms: SLAP-2, SLAP2, A930009E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77799
Homologene: 49989
Slc2a9
Name: solute carrier family 2 (facilitated glucose transporter), member 9
Synonyms: SLC2a9A, SLC2A9B, Glut9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 117591
Homologene: 69290
Cabs1
Name: calcium binding protein, spermatid specific 1
Synonyms: 4931407G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70977
Homologene: 13225
Grm8
Name: glutamate receptor, metabotropic 8
Synonyms: Gprc1h, mGluR8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14823
HGNC: HGNC:4600
Homologene: 654
Ranbp6
Name: RAN binding protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240614
HGNC: HGNC:9851
Homologene: 18935
Acp7
Name: acid phosphatase 7, tartrate resistant
Synonyms: Papl, C330005M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101744
Homologene: 23924
Abcc3
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Fam83e
Name: family with sequence similarity 83, member E
Synonyms: 4930403C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73813
Homologene: 9791
Iqca1l
Name: IQ motif containing with AAA domain 1 like
Synonyms: 4931409K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231045
Homologene: 18602
Fam228a
Name: family with sequence similarity 228, member A
Synonyms: 4930417G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74855
VEGA: 12
Homologene: 54902
Uap1
Name: UDP-N-acetylglucosamine pyrophosphorylase 1
Synonyms: AGX1, SPAG2, ESTM38, AgX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 107652
Homologene: 2342
Cfap100
Name: cilia and flagella associated protein 100
Synonyms: Ccdc37, C030041G11Rik, C230069K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243538
Homologene: 18456
Padi4
Name: peptidyl arginine deiminase, type IV
Synonyms: Pad4, PAD type IV, Pdi4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18602
Homologene: 7883
Fam90a1a
Name: family with sequence similarity 90, member A1A
Synonyms: C86695
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 97476
Homologene: 135718
Cdk14
Name: cyclin-dependent kinase 14
Synonyms: Pftk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18647
HGNC: HGNC:8883
Homologene: 7888
Olfr845
Name: olfactory receptor 845
Synonyms: MOR150-2, MOR150-1P, Olfr1522-ps1, MOR150-1P, GA_x6K02T2PVTD-13076685-13077623, MOR150-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258249
Homologene: 133689
Nom1
Name: nucleolar protein with MIF4G domain 1
Synonyms: D5Kng1, LOC381627, Gm1040
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433864
Homologene: 39776
Aifm1
Name: apoptosis-inducing factor, mitochondrion-associated 1
Synonyms: AIF, apoptosis-inducing factor, AIFsh2, Pdcd8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 26926
HGNC: HGNC:8768
Homologene: 3100
1700001C19Rik
Name: RIKEN cDNA 1700001C19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75462
Homologene: 129540
Lat2
Name: linker for activation of T cells family, member 2
Synonyms: Wbscr15, Wbscr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56743
Homologene: 11297
4930567H17Rik
Name: RIKEN cDNA 4930567H17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 619303
Homologene: 134521
Olfr676
Name: olfactory receptor 676
Synonyms: GA_x6K02T2PBJ9-7664016-7664969, MOR32-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259099
Homologene: 64955
Ugdh
Name: UDP-glucose dehydrogenase
Synonyms: Udpgdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22235
Homologene: 2520
Tmem121b
Name: transmembrane protein 121B
Synonyms: Cecr6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 94047
HGNC: HGNC:1844
Homologene: 12893
Lipt2
Name: lipoyl(octanoyl) transferase 2 (putative)
Synonyms: 2610209A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67164
Homologene: 41659
Atg4a
Name: autophagy related 4A, cysteine peptidase
Synonyms: Apg4a, autophagin 2, Autl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 666468
Homologene: 70873
Magea2
Name: MAGE family member A2
Synonyms: Mage-a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 17138
Homologene: 23188
Hsf3
Name: heat shock transcription factor 3
Synonyms: B230358A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245525
Homologene: 138407
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 37,490,313 bp
  • A to T, chromosome 1 at 170,158,743 bp
  • A to G, chromosome 2 at 30,032,737 bp
  • A to G, chromosome 2 at 119,139,103 bp
  • G to A, chromosome 2 at 126,616,080 bp
  • G to A, chromosome 2 at 156,875,942 bp
  • T to C, chromosome 2 at 172,427,470 bp
  • C to T, chromosome 2 at 172,432,558 bp
  • C to T, chromosome 3 at 62,477,643 bp
  • T to C, chromosome 3 at 87,259,621 bp
  • C to T, chromosome 3 at 96,699,646 bp
  • G to A, chromosome 4 at 140,759,940 bp
  • T to A, chromosome 5 at 4,888,924 bp
  • C to A, chromosome 5 at 24,446,924 bp
  • C to T, chromosome 5 at 24,552,040 bp
  • T to A, chromosome 5 at 29,437,752 bp
  • T to C, chromosome 5 at 38,453,199 bp
  • A to T, chromosome 5 at 65,417,115 bp
  • T to A, chromosome 5 at 73,072,844 bp
  • T to C, chromosome 5 at 87,980,215 bp
  • T to A, chromosome 5 at 124,761,237 bp
  • T to C, chromosome 5 at 134,602,627 bp
  • T to C, chromosome 5 at 137,041,779 bp
  • A to T, chromosome 6 at 27,760,225 bp
  • C to G, chromosome 6 at 90,413,820 bp
  • A to T, chromosome 6 at 120,492,069 bp
  • A to G, chromosome 6 at 120,492,071 bp
  • A to T, chromosome 6 at 121,033,735 bp
  • A to T, chromosome 6 at 142,091,016 bp
  • A to G, chromosome 6 at 147,070,627 bp
  • G to T, chromosome 7 at 19,562,018 bp
  • A to G, chromosome 7 at 19,586,585 bp
  • G to A, chromosome 7 at 26,173,605 bp
  • A to C, chromosome 7 at 28,614,413 bp
  • A to T, chromosome 7 at 30,467,992 bp
  • A to T, chromosome 7 at 42,012,245 bp
  • A to T, chromosome 7 at 45,728,769 bp
  • A to T, chromosome 7 at 45,728,770 bp
  • A to G, chromosome 7 at 72,185,820 bp
  • C to T, chromosome 7 at 100,159,394 bp
  • A to G, chromosome 7 at 102,000,791 bp
  • A to G, chromosome 7 at 105,035,819 bp
  • T to A, chromosome 7 at 114,253,875 bp
  • T to A, chromosome 8 at 21,963,517 bp
  • T to G, chromosome 8 at 21,998,266 bp
  • A to G, chromosome 8 at 25,971,177 bp
  • A to G, chromosome 8 at 44,950,371 bp
  • A to G, chromosome 8 at 107,417,097 bp
  • A to G, chromosome 9 at 19,338,493 bp
  • T to C, chromosome 9 at 32,247,497 bp
  • A to C, chromosome 9 at 67,952,946 bp
  • G to A, chromosome 9 at 70,378,373 bp
  • C to A, chromosome 9 at 87,206,914 bp
  • C to T, chromosome 10 at 79,787,370 bp
  • T to A, chromosome 11 at 72,446,195 bp
  • C to T, chromosome 11 at 94,363,594 bp
  • T to C, chromosome 12 at 4,737,775 bp
  • C to T, chromosome 12 at 83,714,820 bp
  • T to C, chromosome 14 at 101,900,130 bp
  • C to G, chromosome 14 at 118,972,702 bp
  • T to A, chromosome 15 at 66,437,587 bp
  • G to T, chromosome 15 at 75,839,566 bp
  • A to T, chromosome 16 at 45,686,333 bp
  • G to A, chromosome 17 at 35,161,068 bp
  • AC to A, chromosome 17 at 47,433,423 bp
  • C to T, chromosome 17 at 65,852,255 bp
  • A to G, chromosome 17 at 83,477,760 bp
  • C to A, chromosome 18 at 9,993,466 bp
  • A to T, chromosome 18 at 10,150,329 bp
  • A to G, chromosome 18 at 10,503,307 bp
  • G to A, chromosome 19 at 16,682,174 bp
  • A to G, chromosome 19 at 29,811,549 bp
  • A to G, chromosome 19 at 41,883,529 bp
  • A to G, chromosome X at 48,497,468 bp
  • A to T, chromosome X at 70,394,406 bp
  • A to T, chromosome X at 96,320,322 bp
  • A to T, chromosome X at 100,726,131 bp
  • A to G, chromosome X at 140,990,235 bp
  • A to T, chromosome X at 155,027,859 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2257 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040257-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.