Strain Name:
C57BL/6J-MtgxR2279Btlr/Mmmh
Stock Number:
040278-MU
Citation ID:
RRID:MMRRC_040278-MU
Other Names:
R2279 (G1), C57BL/6J-MtgxR2279Btlr
Major Collection:

Gene Information

Dspp
Name: dentin sialophosphoprotein
Synonyms: Dmp3, Dpp, Dsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 666279
HGNC: HGNC:3054
En1
Name: engrailed 1
Synonyms: engrailed-1, Mo-en.1, En-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13798
HGNC: HGNC:3342
Homologene: 50663
Ints6
Name: integrator complex subunit 6
Synonyms: Notch2l, DICE1, 2900075H24Rik, Ddx26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18130
VEGA: 14
Homologene: 8121
Map2k6
Name: mitogen-activated protein kinase kinase 6
Synonyms: SAPKK3, Prkmk6, MKK6, MAP kinase kinase 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 26399
HGNC: HGNC:6846
Homologene: 55686
Arfgef2
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99371
Homologene: 111880
Slc1a6
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms: EAAT4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20513
VEGA: 10
Homologene: 21055
Cnot7
Name: CCR4-NOT transcription complex, subunit 7
Synonyms: Caf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18983
Homologene: 49011
Cdk18
Name: cyclin-dependent kinase 18
Synonyms: Pctk3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18557
HGNC: HGNC:8751
Homologene: 1949
Cltc
Name: clathrin, heavy polypeptide (Hc)
Synonyms: CHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67300
HGNC: HGNC:2092
Homologene: 3572
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: Gtar, A130069E23Rik, 4933425K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 81702
Homologene: 82403
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: ARHGAP10, 5530401C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71435
Homologene: 10822
Ddx42
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Synonyms: SF3b125, B430002H05Rik, 1810047H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72047
Homologene: 49137
Cabin1
Name: calcineurin binding protein 1
Synonyms: Cain, Ppp3in, A330070M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 104248
VEGA: 10
Homologene: 49307
Txlna
Name: taxilin alpha
Synonyms: Txln, IL14, 2600010N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 109658
Homologene: 14062
Epb41l3
Name: erythrocyte membrane protein band 4.1 like 3
Synonyms: NBL3, Epb4.1l3, 4.1B, DAL1P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13823
HGNC: HGNC:3380
Homologene: 49308
Tasor
Name: transcription activation suppressor
Synonyms: D14Abb1e, 4933409E02Rik, MommeD6, Fam208a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218850
VEGA: 14
Homologene: 9062
Tcof1
Name: treacle ribosome biogenesis factor 1
Synonyms: treacle
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 21453
Homologene: 68049
Arhgap42
Name: Rho GTPase activating protein 42
Synonyms: 9030420J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71544
Homologene: 28446
Dbf4
Name: DBF4 zinc finger
Synonyms: Ask
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 27214
Homologene: 40892
Npc1
Name: NPC intracellular cholesterol transporter 1
Synonyms: lcsd, nmf164, D18Ertd723e, C85354, A430089E03Rik, D18Ertd139e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 18145
HGNC: HGNC:7897
Homologene: 228
Nktr
Name: natural killer tumor recognition sequence
Synonyms: D9Wsu172e, 5330401F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Rpn2
Name: ribophorin II
Synonyms: Rpn-2, 1300012C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20014
Homologene: 2214
Mrpl48
Name: mitochondrial ribosomal protein L48
Synonyms: D4Ertd786e, CGI-118, 1810030E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 52443
Homologene: 32294
Dbr1
Name: debranching RNA lariats 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 83703
Homologene: 9428
Kifc5b
Name: kinesin family member C5B
Synonyms: kinesin family c-terminal 5B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16580
VEGA: 17
HGNC: HGNC:6389
Homologene: 83229
Zmiz1
Name: zinc finger, MIZ-type containing 1
Synonyms: Rai17, Zimp10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 328365
Homologene: 10667
Lrrc4c
Name: leucine rich repeat containing 4C
Synonyms: netrin g1 ligand, 6430556C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241568
Homologene: 18696
Spink5
Name: serine peptidase inhibitor, Kazal type 5
Synonyms: LEKT1, 2310065D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 72432
Homologene: 4987
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26875
Homologene: 69111
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: A930014J19Rik, DMPK-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Nesp2g, nesprin-2, syne-2, dice, Cpfl8, 6820443O06Rik, diminished cone electroretinogram
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319565
Homologene: 56700
Gh
Name: growth hormone
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14599
Homologene: 47932
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Gm11639
Name: predicted gene 11639
Synonyms: Efcab15, Gm11639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 105242472
Eogt
Name: EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
Synonyms: A130022J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101351
Homologene: 65276
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20192
Homologene: 68151
Vwf
Name: Von Willebrand factor
Synonyms: B130011O06Rik, 6820430P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 22371
Homologene: 466
Madd
Name: MAP-kinase activating death domain
Synonyms: Rab3 GEP, 9630059K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228355
HGNC: HGNC:6766
Homologene: 14249
Cyp4b1
Name: cytochrome P450, family 4, subfamily b, polypeptide 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13120
HGNC: HGNC:2644
Homologene: 128045
Hcn3
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 3
Synonyms: Hac3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 15168
Homologene: 22453
Rnf32
Name: ring finger protein 32
Synonyms: 1700009J01Rik, Lmbr2, 2700025B22Rik, 4930542N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56874
Homologene: 10986
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75777
Homologene: 44907
Htra1
Name: HtrA serine peptidase 1
Synonyms: insulin-like growth factor binding protein 5 protease, RSPP11, L56, HtrA1, Prss11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56213
HGNC: HGNC:9476
Homologene: 31114
Phactr1
Name: phosphatase and actin regulator 1
Synonyms: 9630030F18Rik, Rpel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218194
Homologene: 33597
Tgm7
Name: transglutaminase 7
Synonyms: TGz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 640543
Homologene: 14192
Olfr786
Name: olfactory receptor 786
Synonyms: MOR111-5, GA_x6K02T2PULF-11116958-11117896
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258542
HGNC: HGNC:8355
Homologene: 133582
Stk-ps2
Name: serine/threonine kinase 2
Synonyms: Gm4776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 212225
AC132131.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Slc25a29
Name: solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29
Synonyms: mCACL, CACL, C030003J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 214663
Homologene: 5385
Cfap410
Name: cilia and flagella associated protein 410
Synonyms: 1810043G02Rik, D10Jhu13e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67884
HGNC: HGNC:1260
Homologene: 3619
Cdh20
Name: cadherin 20
Synonyms: Cdh7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 23836
HGNC: HGNC:1760
Homologene: 8015
Olfr1046
Name: olfactory receptor 1046
Synonyms: MOR194-1, GA_x6K02T2Q125-47692494-47691544
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258575
Homologene: 17301
Dpep1
Name: dipeptidase 1
Synonyms: MBD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13479
HGNC: HGNC:3002
Homologene: 80192
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 277360
Homologene: 10821
Cnga1
Name: cyclic nucleotide gated channel alpha 1
Synonyms: Cncg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12788
HGNC: HGNC:2148
Homologene: 55432
Sorcs2
Name: sortilin-related VPS10 domain containing receptor 2
Synonyms: VPS10 domain receptor protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 81840
Homologene: 56899
Neu1
Name: neuraminidase 1
Synonyms: Bat-7, Bat7, Apl, G9, Neu-1, Aglp, lysosomal sialidase, sialidase 1, Map-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18010
HGNC: HGNC:7758
Homologene: 375
Zfp709
Name: zinc finger protein 709
Synonyms: GIOT-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 236193
Homologene: 136795
Fam50b
Name: family with sequence similarity 50, member B
Synonyms: XAP-5-like, X5L, D0H6S2654E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 108161
VEGA: 13
Homologene: 101669
Mpp2
Name: membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
Synonyms: Dlgh2, Pals4, Dlg2, D11Bwg0652e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 50997
HGNC: HGNC:7220
Homologene: 3920
Gask1a
Name: golgi associated kinase 1A
Synonyms: Fam198a, C730027P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 245050
VEGA: 9
Homologene: 18620
Rhebl1
Name: Ras homolog enriched in brain like 1
Synonyms: 1810036J22Rik, Rheb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69159
Homologene: 5477
Sirt7
Name: sirtuin 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 209011
Homologene: 56152
Gm6994
Name: predicted gene 6994
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 629678
Rsl1d1
Name: ribosomal L1 domain containing 1
Synonyms: 2410005K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66409
Homologene: 41052
Slc30a2
Name: solute carrier family 30 (zinc transporter), member 2
Synonyms: Znt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230810
Homologene: 40855
Sytl3
Name: synaptotagmin-like 3
Synonyms: Slp3, Slp3-a, Slp3-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 83672
Homologene: 12855
Tmem45a
Name: transmembrane protein 45a
Synonyms: C630002M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 56277
Homologene: 41215
Olfr6
Name: olfactory receptor 6
Synonyms: MOR103-16, GA_x6K02T2PBJ9-9337331-9336381, M50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233670
Homologene: 28439
Ifna13
Name: interferon alpha 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230396
HGNC: HGNC:5425
Homologene: 68536
Cptp
Name: ceramide-1-phosphate transfer protein
Synonyms: Gltpd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 79554
Homologene: 11550
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 46,030,071 bp
  • C to A, chromosome 1 at 104,947,414 bp
  • T to A, chromosome 1 at 120,607,187 bp
  • A to T, chromosome 1 at 132,115,952 bp
  • A to G, chromosome 1 at 180,036,919 bp
  • T to C, chromosome 2 at 20,863,226 bp
  • T to C, chromosome 2 at 86,216,804 bp
  • A to T, chromosome 2 at 91,143,683 bp
  • C to T, chromosome 2 at 97,630,505 bp
  • A to T, chromosome 2 at 112,649,319 bp
  • A to G, chromosome 2 at 121,098,564 bp
  • A to G, chromosome 2 at 157,310,288 bp
  • A to T, chromosome 2 at 166,577,955 bp
  • G to C, chromosome 2 at 166,865,759 bp
  • C to A, chromosome 3 at 89,147,861 bp
  • T to A, chromosome 4 at 88,643,919 bp
  • T to A, chromosome 4 at 115,640,360 bp
  • T to C, chromosome 4 at 129,632,142 bp
  • G to T, chromosome 4 at 134,348,546 bp
  • A to G, chromosome 4 at 155,866,421 bp
  • T to C, chromosome 5 at 8,421,333 bp
  • T to A, chromosome 5 at 14,714,273 bp
  • G to T, chromosome 5 at 29,225,280 bp
  • A to T, chromosome 5 at 36,042,086 bp
  • C to T, chromosome 5 at 72,619,061 bp
  • G to T, chromosome 5 at 90,264,717 bp
  • G to A, chromosome 5 at 104,178,384 bp
  • G to T, chromosome 6 at 97,134,301 bp
  • T to C, chromosome 6 at 125,684,143 bp
  • G to A, chromosome 7 at 100,565,264 bp
  • A to T, chromosome 7 at 106,956,627 bp
  • A to T, chromosome 7 at 130,962,022 bp
  • T to C, chromosome 8 at 40,510,012 bp
  • T to C, chromosome 8 at 71,889,090 bp
  • A to T, chromosome 8 at 123,194,144 bp
  • T to C, chromosome 9 at 9,035,511 bp
  • G to T, chromosome 9 at 99,580,147 bp
  • A to G, chromosome 9 at 121,731,537 bp
  • T to C, chromosome 9 at 121,965,602 bp
  • T to C, chromosome 10 at 75,753,461 bp
  • T to C, chromosome 10 at 77,981,642 bp
  • A to T, chromosome 10 at 78,789,048 bp
  • T to C, chromosome 10 at 90,050,096 bp
  • A to T, chromosome 10 at 129,437,657 bp
  • A to G, chromosome 11 at 86,737,283 bp
  • T to C, chromosome 11 at 102,064,301 bp
  • C to A, chromosome 11 at 104,738,359 bp
  • T to A, chromosome 11 at 106,242,939 bp
  • T to C, chromosome 11 at 106,300,787 bp
  • T to C, chromosome 11 at 110,499,464 bp
  • T to C, chromosome 11 at 118,096,561 bp
  • T to C, chromosome 11 at 120,624,495 bp
  • A to G, chromosome 12 at 75,927,466 bp
  • T to C, chromosome 12 at 108,826,926 bp
  • C to T, chromosome 13 at 34,746,840 bp
  • A to T, chromosome 13 at 43,077,789 bp
  • T to C, chromosome 14 at 25,645,652 bp
  • A to C, chromosome 14 at 27,442,495 bp
  • A to G, chromosome 14 at 62,704,682 bp
  • A to G, chromosome 14 at 77,485,995 bp
  • A to G, chromosome 15 at 10,523,592 bp
  • A to T, chromosome 15 at 98,878,286 bp
  • A to T, chromosome 16 at 11,202,306 bp
  • A to T, chromosome 16 at 56,823,519 bp
  • A to G, chromosome 17 at 6,708,874 bp
  • A to G, chromosome 17 at 26,925,541 bp
  • A to G, chromosome 17 at 34,934,374 bp
  • A to G, chromosome 17 at 69,270,650 bp
  • T to C, chromosome 18 at 12,197,179 bp
  • A to G, chromosome 18 at 43,986,329 bp
  • A to G, chromosome 18 at 60,831,685 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2279 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040278-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.