Strain Name:
C57BL/6J-MtgxR2332Btlr/Mmmh
Stock Number:
040322-MU
Citation ID:
RRID:MMRRC_040322-MU
Other Names:
R2332 (G1), C57BL/6J-MtgxR2332Btlr
Major Collection:

Gene Information

Fga
Name: fibrinogen alpha chain
Synonyms: ENSMUSG00000059807, Fib
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14161
HGNC: HGNC:3661
Homologene: 428
Cdk13
Name: cyclin-dependent kinase 13
Synonyms: 2310015O17Rik, Cdc2l5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 69562
VEGA: 13
HGNC: HGNC:1733
Homologene: 135707
Synj2
Name: synaptojanin 2
Synonyms: SJ2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20975
Homologene: 117703
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: Bwf1, 2610509D04Rik, Alfy, Bchs, Ggtb3, D5Ertd66e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72145
Homologene: 22855
Patj
Name: PATJ, crumbs cell polarity complex component
Synonyms: Inadl, Cipp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12695
Homologene: 72199
Setx
Name: senataxin
Synonyms: Als4, A930037J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Pds5a
Name: PDS5 cohesin associated factor A
Synonyms: E230024D05Rik, 9030416H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71521
Homologene: 22877
Dnaja2
Name: DnaJ heat shock protein family (Hsp40) member A2
Synonyms: PRO3015, 1500017M13Rik, 2010206B19Rik, HIRIP4, DNJ3, mDj3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56445
Homologene: 21193
Uhrf1
Name: ubiquitin-like, containing PHD and RING finger domains, 1
Synonyms: ICBP90, Np95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18140
Homologene: 7866
Hoxa5
Name: homeobox A5
Synonyms: Hox-1.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15402
HGNC: HGNC:5106
Homologene: 40726
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230895
Homologene: 15583
Hjurp
Name: Holliday junction recognition protein
Synonyms: 6430706D22Rik, A730008H23Rik, C330011F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Rmdn3
Name: regulator of microtubule dynamics 3
Synonyms: 1200015F23Rik, Fam82a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67809
Homologene: 34926
Apc
Name: APC, WNT signaling pathway regulator
Synonyms: adenomatosis polyposis coli, CC1, Min
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11789
HGNC: HGNC:583
Homologene: 30950
Wtap
Name: WT1 associating protein
Synonyms: 2810408K05Rik, 9430038B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 60532
Homologene: 68422
Trhde
Name: TRH-degrading enzyme
Synonyms: 9330155P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237553
Homologene: 75007
Iqcb1
Name: IQ calmodulin-binding motif containing 1
Synonyms: 6820449I09Rik, NPHP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320299
Homologene: 8766
Hps6
Name: HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
Synonyms: Hermansky-Pudlak syndrome 6, BLOC-2, 5330434M19Rik, ruby eye, ru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20170
VEGA: 19
Homologene: 11691
Ghr
Name: growth hormone receptor
Synonyms: GHR/BP, GHBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14600
HGNC: HGNC:4263
Homologene: 134
Ttn
Name: titin
Synonyms: 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, mdm, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru, connectin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Depdc1a
Name: DEP domain containing 1a
Synonyms: 5830484J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76131
Homologene: 9834
Apoa4
Name: apolipoprotein A-IV
Synonyms: Apoa-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11808
HGNC: HGNC:602
Homologene: 47927
Sh3rf1
Name: SH3 domain containing ring finger 1
Synonyms: Posh, 2200003J05Rik, Sh3md2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 59009
Homologene: 10988
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269356
Homologene: 12931
Rhobtb3
Name: Rho-related BTB domain containing 3
Synonyms: 1700040C17Rik, 2610033K01Rik, 4930503C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 73296
Homologene: 8932
Ppp1r9b
Name: protein phosphatase 1, regulatory subunit 9B
Synonyms: spinophilin, SPL, Spn, neurabin II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217124
HGNC: HGNC:9298
Homologene: 32787
Map3k13
Name: mitogen-activated protein kinase kinase kinase 13
Synonyms: C130026N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71751
VEGA: 16
HGNC: HGNC:6852
Homologene: 37958
Ddx60
Name: DExD/H box helicase 60
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234311
Homologene: 23031
Or10ag53
Name: olfactory receptor family 10 subfamily AG member 53
Synonyms: MOR273-4P, Olfr1115, MOR273-4P, MOR264-20, GA_x6K02T2Q125-48736906-48737886, Olfr1530-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258294
Homologene: 27114
Speer4f1
Name: spermatogenesis associated glutamate (E)-rich protein 4F1
Synonyms: SPEER-4F, Speer4f, 4922502J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70935
Homologene: 69402
Rimbp2
Name: RIMS binding protein 2
Synonyms: A930033C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231760
Homologene: 14672
Fut9
Name: fucosyltransferase 9
Synonyms: mFUT9, mFuc-TIX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14348
HGNC: HGNC:4020
Homologene: 4800
Wnt4
Name: wingless-type MMTV integration site family, member 4
Synonyms: Wnt-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22417
Homologene: 22529
Cep250
Name: centrosomal protein 250
Synonyms: B230210E21Rik, Cep2, Inmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Sstr4
Name: somatostatin receptor 4
Synonyms: Smstr4, sst4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20608
Homologene: 20286
Pacsin1
Name: protein kinase C and casein kinase substrate in neurons 1
Synonyms: A830061D09Rik, Syndapin I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 23969
HGNC: HGNC:8570
Homologene: 22674
Fam186b
Name: family with sequence similarity 186, member B
Synonyms: EG545136
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 545136
VEGA: 15
Homologene: 69502
Ap3m2
Name: adaptor-related protein complex 3, mu 2 subunit
Synonyms: 5830445E16Rik, AP-3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 64933
HGNC: HGNC:570
Homologene: 4950
Or52d13
Name: olfactory receptor family 52 subfamily D member 13
Synonyms: Gm15121, EG546989, GA_x6K02T2PBJ9-6182881-6181898, MOR33-3P, Olfr607
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546989
Homologene: 78211
Zfp322a
Name: zinc finger protein 322A
Synonyms: 9630054P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218100
Homologene: 23460
Ugdh
Name: UDP-glucose dehydrogenase
Synonyms: Udpgdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22235
Homologene: 2520
Crygs
Name: crystallin, gamma S
Synonyms: Opj
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12970
VEGA: 16
HGNC: HGNC:2417
Homologene: 40695
Gm10287
Name: predicted gene 10287
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Rpl31-ps17
Name: ribosomal protein L31, pseudogene 17
Synonyms: Gm16382
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 673582
Gm5444
Name: predicted gene 5444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Banf1
Name: BAF nuclear assembly factor 1
Synonyms: Bcrp1, barrier to autointegration factor 1, C78287
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 23825
VEGA: 19
Homologene: 2866
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to C, chromosome 1 at 88,277,215 bp
  • GTGGCT to GT, chromosome 2 at 29,154,061 bp
  • A to T, chromosome 2 at 76,781,139 bp
  • T to C, chromosome 2 at 87,252,873 bp
  • A to T, chromosome 2 at 119,153,527 bp
  • A to T, chromosome 2 at 130,684,459 bp
  • A to T, chromosome 2 at 148,396,410 bp
  • A to G, chromosome 2 at 155,990,607 bp
  • T to C, chromosome 3 at 83,031,397 bp
  • T to C, chromosome 3 at 149,224,940 bp
  • C to A, chromosome 3 at 159,523,866 bp
  • C to T, chromosome 4 at 25,619,823 bp
  • G to A, chromosome 4 at 98,687,318 bp
  • C to A, chromosome 4 at 137,296,520 bp
  • G to T, chromosome 4 at 145,148,686 bp
  • C to A, chromosome 5 at 17,479,524 bp
  • C to T, chromosome 5 at 65,427,484 bp
  • A to G, chromosome 5 at 65,627,079 bp
  • A to G, chromosome 5 at 101,888,323 bp
  • A to G, chromosome 5 at 128,789,641 bp
  • T to C, chromosome 6 at 52,202,679 bp
  • A to G, chromosome 7 at 103,461,086 bp
  • A to G, chromosome 8 at 22,797,231 bp
  • C to T, chromosome 8 at 61,226,287 bp
  • A to G, chromosome 8 at 62,037,091 bp
  • G to A, chromosome 8 at 85,540,136 bp
  • G to A, chromosome 9 at 46,242,355 bp
  • T to A, chromosome 10 at 114,592,165 bp
  • A to T, chromosome 11 at 94,996,609 bp
  • C to T, chromosome 12 at 54,701,612 bp
  • A to T, chromosome 13 at 4,833,625 bp
  • A to G, chromosome 13 at 17,718,695 bp
  • A to T, chromosome 13 at 23,357,324 bp
  • A to G, chromosome 13 at 75,910,852 bp
  • T to C, chromosome 15 at 3,320,409 bp
  • T to A, chromosome 15 at 99,280,428 bp
  • G to A, chromosome 16 at 21,898,677 bp
  • C to T, chromosome 16 at 22,805,551 bp
  • A to G, chromosome 16 at 36,843,439 bp
  • A to G, chromosome 17 at 6,023,794 bp
  • C to T, chromosome 17 at 12,967,538 bp
  • A to G, chromosome 17 at 27,704,911 bp
  • C to A, chromosome 17 at 56,310,671 bp
  • T to C, chromosome 18 at 34,317,059 bp
  • C to T, chromosome 19 at 5,365,030 bp
  • T to C, chromosome 19 at 46,004,491 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2332 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040322-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.