Strain Name:
C57BL/6J-MtgxR2356Btlr/Mmmh
Stock Number:
040338-MU
Citation ID:
RRID:MMRRC_040338-MU
Other Names:
R2356 (G1), C57BL/6J-MtgxR2356Btlr
Major Collection:

Gene Information

Itga8
Name: integrin alpha 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241226
HGNC: HGNC:6144
Homologene: 37396
Apoa5
Name: apolipoprotein A-V
Synonyms: 1300007O05Rik, RAP3, Apoav
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66113
Homologene: 14197
Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Synonyms: Her4, ErbB4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13869
HGNC: HGNC:3432
Homologene: 21084
Zfp809
Name: zinc finger protein 809
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235047
VEGA: 9
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DOXNPH, DNAPDcs, DNA-PK, slip, dxnph, XRCC7, DNA-PKcs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Matk
Name: megakaryocyte-associated tyrosine kinase
Synonyms: HYL, Csk homologous kinase, Ntk, CHK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17179
HGNC: HGNC:6906
Homologene: 48104
Cxcr4
Name: chemokine (C-X-C motif) receptor 4
Synonyms: Cmkar4, PB-CKR, fusin, Sdf1r, b2b220Clo, CD184
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12767
HGNC: HGNC:2561
Homologene: 20739
Dapp1
Name: dual adaptor for phosphotyrosine and 3-phosphoinositides 1
Synonyms: Bam32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26377
Homologene: 32138
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216860
Homologene: 13029
Ppp4r1
Name: protein phosphatase 4, regulatory subunit 1
Synonyms: 3110001J10Rik, Pp4r1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70351
HGNC: HGNC:9320
Homologene: 81737
Cdc6
Name: cell division cycle 6
Synonyms: CDC18L, cell division cycle 18 homolog (S.pombe)-like, CDC18(S.pombe)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23834
HGNC: HGNC:1744
Homologene: 68172
En2
Name: engrailed 2
Synonyms: En-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13799
HGNC: HGNC:3343
Homologene: 55579
Sec23ip
Name: Sec23 interacting protein
Synonyms: p125, D7Ertd373e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207352
Homologene: 38288
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320365
Homologene: 113770
Exoc5
Name: exocyst complex component 5
Synonyms: SEC10, Sec10l1, PRO1912
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105504
Homologene: 38195
Rnf40
Name: ring finger protein 40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233900
Homologene: 8856
Psmd14
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Synonyms: 2610312C03Rik, Pad1, 3200001M20Rik, POH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 59029
Homologene: 4240
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: tbl, D130015N03Rik, 2810449H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Map3k20
Name: mitogen-activated protein kinase kinase kinase 20
Synonyms: MLTKalpha, Zak, MLTKbeta, B230120H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65964
Homologene: 32331
Psip1
Name: PC4 and SFRS1 interacting protein 1
Synonyms: Psip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 101739
HGNC: HGNC:9527
Homologene: 13242
Rnf114
Name: ring finger protein 114
Synonyms: Znf228, 1110008J21Rik, Zfp313
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 81018
Homologene: 10265
Nbn
Name: nibrin
Synonyms: Nbs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 27354
HGNC: HGNC:7652
Homologene: 1858
Dusp11
Name: dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Synonyms: 2010300F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 72102
HGNC: HGNC:3066
Homologene: 31183
Ipo9
Name: importin 9
Synonyms: 0710008K06Rik, Imp9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226432
Homologene: 5874
Rcor1
Name: REST corepressor 1
Synonyms: D12Wsu95e, 6720480E22Rik, Rocr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217864
Homologene: 32246
Lmo7
Name: LIM domain only 7
Synonyms: LOC380928, FBXO20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Cyp4a30-ps
Name: cytochrome P450, family 4, subfamily a, member 30, pseudogene
Synonyms: Gm12836
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 546842
Atp13a5
Name: ATPase type 13A5
Synonyms: C630015F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268878
Homologene: 77451
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Foxk1
Name: forkhead box K1
Synonyms: Mnf, A630048H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17425
Homologene: 82414
Abcf3
Name: ATP-binding cassette, sub-family F (GCN20), member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27406
HGNC: HGNC:72
Homologene: 22784
Psmd11
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Synonyms: P44.5, C78232, 2610024G20Rik, 1700089D09Rik, S9, 1810019E17Rik, 2810055C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69077
HGNC: HGNC:9556
Homologene: 2108
Arhgap44
Name: Rho GTPase activating protein 44
Synonyms: AU040829
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216831
Homologene: 65284
Cdk10
Name: cyclin-dependent kinase 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234854
HGNC: HGNC:1770
Homologene: 55769
Scgb3a1
Name: secretoglobin, family 3A, member 1
Synonyms: UGRP2, HIN-1, LuLeu2, 1110030K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68662
Homologene: 14160
Trhde
Name: TRH-degrading enzyme
Synonyms: 9330155P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237553
Homologene: 75007
Mst1r
Name: macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Synonyms: CDw136, friend virus susceptibility 2, PTK8, Fv-2, Ron, Fv2, STK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19882
HGNC: HGNC:7381
Homologene: 1835
Ank1
Name: ankyrin 1, erythroid
Synonyms: Ank-1, pale
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11733
HGNC: HGNC:492
Homologene: 55427
Prkaa2
Name: protein kinase, AMP-activated, alpha 2 catalytic subunit
Synonyms: AMPKalpha2, 2310008I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 108079
HGNC: HGNC:9377
Homologene: 4551
Clcn1
Name: chloride channel, voltage-sensitive 1
Synonyms: Clc1, SMCC1, nmf355, Clc-1, NMF355
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12723
HGNC: HGNC:2019
Homologene: 63
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Zfp429
Name: zinc finger protein 429
Synonyms: 2810487A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72807
Homologene: 110878
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: 1810073P09Rik, X83337, ESTM15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75607
Homologene: 19155
Arhgap5
Name: Rho GTPase activating protein 5
Synonyms: p190-B, p190B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11855
VEGA: 12
HGNC: HGNC:675
Homologene: 907
Tulp2
Name: tubby-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56734
Homologene: 2492
Pik3r5
Name: phosphoinositide-3-kinase regulatory subunit 5
Synonyms: p101, Foap2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 320207
Homologene: 8627
Shroom1
Name: shroom family member 1
Synonyms: 1300007L22Rik, Shrm1, Apx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71774
Homologene: 12411
4932415D10Rik
Name: RIKEN cDNA 4932415D10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Plekhn1
Name: pleckstrin homology domain containing, family N member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 231002
VEGA: 4
Homologene: 12949
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 2310021P13Rik, 4832404P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268721
VEGA: 14
Homologene: 34313
Dlg5
Name: discs large MAGUK scaffold protein 5
Synonyms: 4933429D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71228
HGNC: HGNC:2904
Homologene: 3486
Ces2h
Name: carboxylesterase 2H
Synonyms: Gm5744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 436059
HGNC: HGNC:1864
Homologene: 128645
Ncln
Name: nicalin
Synonyms: 3100002P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103425
Homologene: 10604
Serpina3f
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3F
Synonyms: alpha-1 antiproteinasin, antitrypsin, 2A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238393
HGNC: HGNC:16
Homologene: 115927
Adcy6
Name: adenylate cyclase 6
Synonyms: AC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11512
VEGA: 15
HGNC: HGNC:237
Homologene: 22400
Smg8
Name: smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
Synonyms: 1200011M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74133
Homologene: 32393
Gpx5
Name: glutathione peroxidase 5
Synonyms: Arep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14780
HGNC: HGNC:4557
Homologene: 1155
Klf11
Name: Kruppel-like factor 11
Synonyms: Tieg3, Tieg2b, Tieg2, D12Ertd427e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 194655
Homologene: 2668
Prss40
Name: protease, serine 40
Synonyms: Tesp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21756
Homologene: 69043
Itih4
Name: inter alpha-trypsin inhibitor, heavy chain 4
Synonyms: Itih-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16427
HGNC: HGNC:6169
Homologene: 1670
Mcmdc2
Name: minichromosome maintenance domain containing 2
Synonyms: 6030422M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240697
Homologene: 18309
Dnaaf1
Name: dynein, axonemal assembly factor 1
Synonyms: m4Bei, 4930457P18Rik, Lrrc50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 68270
Homologene: 12256
Dnaaf2
Name: dynein, axonemal assembly factor 2
Synonyms: Ktu, 2810020C19Rik, 1110034A24Rik, kintoun
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109065
Homologene: 10026
Gm9573
Name: predicted gene 9573
Synonyms: Muc21, epiglycanin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 672682
Cyp3a11
Name: cytochrome P450, family 3, subfamily a, polypeptide 11
Synonyms: Cyp3a, IIIAm1, Pcn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13112
HGNC: HGNC:2638
Homologene: 133568
Setd4
Name: SET domain containing 4
Synonyms: ORF21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224440
HGNC: HGNC:1258
Homologene: 41173
Dhrs7
Name: dehydrogenase/reductase (SDR family) member 7
Synonyms: 2310016E22Rik, 5730564L20Rik, retDSR4, retSDR4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66375
VEGA: 12
Homologene: 9350
Prx
Name: periaxin
Synonyms: L-Periaxin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19153
Homologene: 76542
Gata6
Name: GATA binding protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 14465
VEGA: 18
HGNC: HGNC:4174
Homologene: 68449
Slc30a3
Name: solute carrier family 30 (zinc transporter), member 3
Synonyms: Znt3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22784
Homologene: 74470
Nlrp4g
Name: NLR family, pyrin domain containing 4G
Synonyms: nalp4g
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235779
VEGA: 9
Vmn1r212
Name: vomeronasal 1 receptor 212
Synonyms: V1rh18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171275
Homologene: 110880
Krtap8-1
Name: keratin associated protein 8-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16703
VEGA: 16
Nipa2
Name: non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
Synonyms: 2600017P10Rik, 3830408P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 93790
Homologene: 11368
Olfr768
Name: olfactory receptor 768
Synonyms: GA_x6K02T2PULF-10779441-10778503, MOR114-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258863
Homologene: 17159
Aph1a
Name: aph1 homolog A, gamma secretase subunit
Synonyms: 6530402N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 226548
Homologene: 9345
Olfr657
Name: olfactory receptor 657
Synonyms: GA_x6K02T2PBJ9-7263864-7264823, MOR40-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258309
Homologene: 17189
Ceacam11
Name: carcinoembryonic antigen-related cell adhesion molecule 11
Synonyms: Ceacam11-C1, Ceacam11-C4, Ceacam11-C3, 1600015D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66996
Homologene: 135962
Gm8225
Name: predicted gene 8225
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 666668
VEGA: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 9,930,801 bp
  • A to T, chromosome 1 at 34,559,903 bp
  • T to A, chromosome 1 at 68,078,596 bp
  • A to G, chromosome 1 at 128,589,514 bp
  • A to T, chromosome 1 at 135,406,817 bp
  • T to C, chromosome 2 at 12,200,141 bp
  • A to T, chromosome 2 at 61,800,007 bp
  • A to G, chromosome 2 at 72,435,216 bp
  • C to A, chromosome 2 at 167,512,636 bp
  • T to C, chromosome 3 at 95,894,232 bp
  • A to G, chromosome 3 at 137,937,749 bp
  • T to A, chromosome 4 at 15,970,863 bp
  • A to G, chromosome 4 at 83,460,148 bp
  • C to T, chromosome 4 at 105,039,721 bp
  • C to A, chromosome 4 at 115,344,261 bp
  • T to G, chromosome 4 at 156,222,701 bp
  • G to T, chromosome 5 at 28,166,332 bp
  • C to T, chromosome 5 at 31,088,594 bp
  • G to T, chromosome 5 at 124,821,211 bp
  • A to G, chromosome 5 at 142,455,409 bp
  • C to A, chromosome 5 at 145,862,521 bp
  • G to A, chromosome 5 at 150,471,432 bp
  • G to A, chromosome 6 at 42,291,625 bp
  • A to G, chromosome 6 at 85,953,365 bp
  • A to G, chromosome 7 at 17,972,316 bp
  • C to T, chromosome 7 at 27,507,859 bp
  • A to T, chromosome 7 at 45,518,628 bp
  • G to A, chromosome 7 at 55,932,966 bp
  • G to T, chromosome 7 at 104,636,627 bp
  • T to G, chromosome 7 at 127,591,576 bp
  • T to A, chromosome 7 at 128,766,286 bp
  • A to T, chromosome 8 at 23,085,672 bp
  • G to A, chromosome 8 at 105,015,938 bp
  • T to A, chromosome 8 at 119,588,287 bp
  • T to C, chromosome 8 at 123,229,169 bp
  • C to A, chromosome 9 at 22,243,040 bp
  • T to A, chromosome 9 at 46,270,043 bp
  • T to C, chromosome 9 at 66,414,406 bp
  • T to A, chromosome 9 at 107,917,870 bp
  • A to G, chromosome 9 at 124,349,306 bp
  • G to A, chromosome 10 at 81,261,543 bp
  • A to G, chromosome 10 at 81,492,922 bp
  • A to G, chromosome 10 at 82,283,955 bp
  • T to C, chromosome 10 at 114,401,516 bp
  • T to C, chromosome 10 at 129,093,892 bp
  • A to T, chromosome 11 at 49,664,362 bp
  • A to T, chromosome 11 at 53,466,447 bp
  • T to C, chromosome 11 at 65,010,025 bp
  • T to C, chromosome 11 at 68,492,917 bp
  • T to A, chromosome 11 at 69,904,520 bp
  • T to A, chromosome 11 at 80,428,704 bp
  • G to C, chromosome 11 at 87,085,728 bp
  • A to G, chromosome 11 at 98,919,292 bp
  • T to C, chromosome 12 at 24,653,583 bp
  • C to T, chromosome 12 at 52,519,147 bp
  • A to G, chromosome 12 at 69,198,218 bp
  • A to C, chromosome 12 at 72,652,381 bp
  • G to T, chromosome 12 at 104,217,367 bp
  • T to C, chromosome 12 at 111,109,792 bp
  • G to C, chromosome 13 at 21,291,368 bp
  • A to T, chromosome 13 at 22,883,950 bp
  • A to T, chromosome 13 at 49,039,168 bp
  • A to G, chromosome 13 at 67,390,627 bp
  • A to T, chromosome 14 at 20,710,634 bp
  • A to G, chromosome 14 at 24,170,428 bp
  • C to T, chromosome 14 at 30,890,634 bp
  • T to C, chromosome 14 at 49,016,281 bp
  • T to C, chromosome 14 at 101,886,945 bp
  • C to T, chromosome 15 at 44,533,019 bp
  • A to T, chromosome 15 at 98,597,016 bp
  • T to A, chromosome 16 at 15,684,204 bp
  • G to T, chromosome 16 at 20,560,499 bp
  • A to T, chromosome 16 at 29,281,069 bp
  • A to T, chromosome 16 at 89,487,901 bp
  • G to T, chromosome 16 at 89,487,902 bp
  • G to A, chromosome 16 at 93,590,983 bp
  • T to C, chromosome 17 at 26,543,404 bp
  • A to G, chromosome 17 at 35,621,671 bp
  • T to A, chromosome 17 at 65,833,050 bp
  • T to A, chromosome 17 at 67,810,114 bp
  • A to T, chromosome 18 at 11,084,310 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2356 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040338-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.