Strain Name:
C57BL/6J-MtgxR2516Btlr/Mmmh
Stock Number:
040420-MU
Citation ID:
RRID:MMRRC_040420-MU
Other Names:
R2516 (G1), C57BL/6J-MtgxR2516Btlr
Major Collection:

Gene Information

Gsn
Name: gelsolin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227753
VEGA: 2
HGNC: HGNC:4620
Homologene: 147
Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 104245
VEGA: 7
Homologene: 37901
App
Name: amyloid beta (A4) precursor protein
Synonyms: Adap, Abeta, appican, betaAPP, E030013M08Rik, Cvap, protease nexin II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 11820
VEGA: 16
HGNC: HGNC:620
Homologene: 56379
Il4i1
Name: interleukin 4 induced 1
Synonyms: H-46, H-4, H4, Fig1, Fig1-ps, H46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14204
VEGA: 7
Homologene: 22567
Wdr47
Name: WD repeat domain 47
Synonyms: 1810073M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99512
VEGA: 3
Homologene: 8984
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: C630029C19Rik, nur14, NaCh6, med, seal, motor end-plate disease, nmf2, mnd-2, mnd2, NMF335, ataxia 3, nmf335, Nav1.6, nmf58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20273
VEGA: 15
Homologene: 7927
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: ARHGAP10, 5530401C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71435
VEGA: 2
Homologene: 10822
Drosha
Name: drosha, ribonuclease type III
Synonyms: Rnasen, Etohi2, 1110013A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14000
VEGA: 15
Homologene: 8293
Cep104
Name: centrosomal protein 104
Synonyms: BC046331
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230967
VEGA: 4
Homologene: 44919
Arfgef1
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
Synonyms: D130059B05Rik, BIG1, ARFGEP1, P200, D730028O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 211673
VEGA: 1
Homologene: 4687
Rif1
Name: replication timing regulatory factor 1
Synonyms: D2Ertd145e, 6530403D07Rik, 5730435J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 51869
VEGA: 2
Homologene: 41231
Laptm4a
Name: lysosomal-associated protein transmembrane 4A
Synonyms: Mtrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 17775
VEGA: 12
HGNC: HGNC:6924
Homologene: 7427
Aen
Name: apoptosis enhancing nuclease
Synonyms: 2700083B06Rik, Isg20l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68048
VEGA: 7
Homologene: 23382
Mnat1
Name: menage a trois 1
Synonyms: E130115E11Rik, MAT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 17420
VEGA: 12
HGNC: HGNC:7181
Homologene: 1821
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235380
VEGA: 9
HGNC: HGNC:2938
Homologene: 41022
Ptprj
Name: protein tyrosine phosphatase, receptor type, J
Synonyms: Byp, CD148, DEP-1, RPTPJ, Scc-1, Scc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19271
VEGA: 2
HGNC: HGNC:9673
Homologene: 2130
Uchl1
Name: ubiquitin carboxy-terminal hydrolase L1
Synonyms: PGP 9.5, PGP9.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22223
VEGA: 5
Homologene: 37894
Nars
Name: asparaginyl-tRNA synthetase
Synonyms: ASNRS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70223
VEGA: 18
HGNC: HGNC:7643
Homologene: 68404
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, 4921513O20Rik, D630001M17Rik, 9330188B09Rik, LOC381026
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 66725
VEGA: 15
Homologene: 18982
Slc10a4
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231290
VEGA: 5
Homologene: 15495
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 236266
VEGA: 6
HGNC: HGNC:428
Homologene: 49406
Zc3h18
Name: zinc finger CCCH-type containing 18
Synonyms: 5830416A07Rik, 1190001B23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76014
VEGA: 8
Homologene: 44894
Atf7
Name: activating transcription factor 7
Synonyms: 9430065F09Rik, C130020M04Rik, 1110012F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223922
VEGA: 15
HGNC: HGNC:792
Homologene: 4994
Lpl
Name: lipoprotein lipase
Synonyms: O 1-4-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16956
VEGA: 8
HGNC: HGNC:6677
Homologene: 200
Mfsd2a
Name: major facilitator superfamily domain containing 2A
Synonyms: Mfsd2, 1700018O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 76574
VEGA: 4
Homologene: 19229
Oit3
Name: oncoprotein induced transcript 3
Synonyms: EF-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18302
VEGA: 10
Homologene: 7870
Alas1
Name: aminolevulinic acid synthase 1
Synonyms: succinyl-CoA: glycine C-succinyl transferase, 5-aminolevulinate synthase, ALAS-N, Alas-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11655
VEGA: 9
HGNC: HGNC:396
Homologene: 55478
Gmds
Name: GDP-mannose 4, 6-dehydratase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218138
VEGA: 13
HGNC: HGNC:4369
Homologene: 75968
Afg3l1
Name: AFG3-like AAA ATPase 1
Synonyms: 3110061K15Rik, 1700047G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 114896
VEGA: 8
HGNC: HGNC:314
Homologene: 134198
Mtus1
Name: mitochondrial tumor suppressor 1
Synonyms: Atip1, MTSG1, B430305I03Rik, MD44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102103
VEGA: 8
Homologene: 100292
Rufy1
Name: RUN and FYVE domain containing 1
Synonyms: 3000002E04Rik, ZFYVE12, Rabip4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216724
VEGA: 11
Homologene: 23522
Exosc9
Name: exosome component 9
Synonyms: p6, RRP45, Pmscl1, PM/Scl-75, p5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 50911
VEGA: 3
HGNC: HGNC:9137
Homologene: 3693
Capn11
Name: calpain 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268958
VEGA: 17
HGNC: HGNC:1478
Homologene: 21392
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 80892
VEGA: 3
Homologene: 23477
Tab2
Name: TGF-beta activated kinase 1/MAP3K7 binding protein 2
Synonyms: Tak1 binding protein 2, A530078N03Rik, 1110030N06Rik, Map3k7ip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 68652
VEGA: 10
Homologene: 9019
Mmrn2
Name: multimerin 2
Synonyms: ENDOGLYX1, EndoGlyx-1, Emilin3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105450
VEGA: 14
Homologene: 11697
Slc1a1
Name: solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
Synonyms: D130048G10Rik, EAAT3, MEAAC1, EAAC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20510
VEGA: 19
Homologene: 20881
Khdrbs3
Name: KH domain containing, RNA binding, signal transduction associated 3
Synonyms: SLM-2, Etle, T-STAR, Salp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 13992
VEGA: 15
Homologene: 4780
Sycp1
Name: synaptonemal complex protein 1
Synonyms: SCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20957
VEGA: 3
Homologene: 2389
Ankrd65
Name: ankyrin repeat domain 65
Synonyms: E230028L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242805
VEGA: 4
Homologene: 28427
Abcb11
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Synonyms: sister of P-glycoprotein, Lith1, Bsep, PFIC2, ABC16, PGY4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27413
VEGA: 2
HGNC: HGNC:42
Homologene: 74509
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: Mtr1, Ltrpc5, 9430099A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56843
VEGA: 7
Homologene: 22818
Sos2
Name: SOS Ras/Rho guanine nucleotide exchange factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20663
VEGA: 12
Homologene: 38253
Msto1
Name: misato 1, mitochondrial distribution and morphology regulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229524
VEGA: 3
Homologene: 41228
Fbxw7
Name: F-box and WD-40 domain protein 7
Synonyms: Fbxw6, AGO, Cdc4, Fbw7, SEL-10, 1110001A17Rik, Fbxo30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 50754
VEGA: 3
Homologene: 117451
Pls1
Name: plastin 1 (I-isoform)
Synonyms: I-fimbrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102502
VEGA: 9
HGNC: HGNC:9090
Homologene: 68270
Unc5d
Name: unc-5 netrin receptor D
Synonyms: D930029E11Rik, Unc5h4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 210801
VEGA: 8
Homologene: 15450
Kcnv2
Name: potassium channel, subfamily V, member 2
Synonyms: KV11.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240595
VEGA: 19
Homologene: 26423
Fut1
Name: fucosyltransferase 1
Synonyms: H transferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14343
VEGA: 7
HGNC: HGNC:4012
Homologene: 120
Olfr801
Name: olfactory receptor 801
Synonyms: GA_x6K02T2PULF-11349138-11348182, MOR110-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258282
VEGA: 10
Homologene: 138306
Plekhn1
Name: pleckstrin homology domain containing, family N member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 231002
VEGA: 4
Homologene: 12949
P2rx1
Name: purinergic receptor P2X, ligand-gated ion channel, 1
Synonyms: RP-2, P2X1 receptor, P2x, Pdcd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18436
VEGA: 11
HGNC: HGNC:8533
Homologene: 1921
Clca3a1
Name: chloride channel accessory 3A1
Synonyms: Clca1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12722
VEGA: 3
Homologene: 77224
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: STEF, 3000002F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 24001
VEGA: 17
Homologene: 40796
Olfr1024
Name: olfactory receptor 1024
Synonyms: MOR197-1, GA_x6K02T2Q125-47384320-47383337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257900
VEGA: 2
Homologene: 128271
Sphkap
Name: SPHK1 interactor, AKAP domain containing
Synonyms: A930009L15Rik, SKIP, 4930544G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 77629
VEGA: 1
Homologene: 18172
Stom
Name: stomatin
Synonyms: stomatin, Epb7.2, protein 7.2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13830
VEGA: 2
HGNC: HGNC:3383
Homologene: 81681
Slc22a8
Name: solute carrier family 22 (organic anion transporter), member 8
Synonyms: mOat3, Roct, OAT3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 19879
VEGA: 19
Homologene: 20901
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 19309
VEGA: 19
HGNC: HGNC:9726
Homologene: 2145
Kndc1
Name: kinase non-catalytic C-lobe domain (KIND) containing 1
Synonyms: very-kind, 2410012C07Rik, B830014K08Rik, VKIND
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76484
VEGA: 7
Homologene: 45138
Best1
Name: bestrophin 1
Synonyms: mBest1, best macular dystrophy, Vmd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 24115
VEGA: 19
Homologene: 37895
Cyp3a25
Name: cytochrome P450, family 3, subfamily a, polypeptide 25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56388
VEGA: 5
Homologene: 135775
Irak1bp1
Name: interleukin-1 receptor-associated kinase 1 binding protein 1
Synonyms: AIP70, SIMPL, 4921528N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 65099
VEGA: 9
Homologene: 11300
Olfr1467
Name: olfactory receptor 1467
Synonyms: MOR202-15, GA_x6K02T2RE5P-3695694-3696620
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258686
VEGA: 19
Homologene: 133888
Vmn2r97
Name: vomeronasal 2, receptor 97
Synonyms: EG627367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627367
VEGA: 17
Homologene: 115024
Arhgap24
Name: Rho GTPase activating protein 24
Synonyms: 0610025G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231532
VEGA: 5
Homologene: 32754
Ctsm
Name: cathepsin M
Synonyms: 1600027J17Rik, Catm, Cat M
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 64139
VEGA: 13
Homologene: 75181
Gm572
Name: predicted gene 572
Synonyms: LOC230909, b2b1167Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230909
VEGA: 4
Homologene: 52134
Vmn1r232
Name: vomeronasal 1 receptor 232
Synonyms: V1re4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 171227
VEGA: 17
Homologene: 121611
Pecr
Name: peroxisomal trans-2-enoyl-CoA reductase
Synonyms: 2400003B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 111175
VEGA: 1
Homologene: 69255
Olfr728
Name: olfactory receptor 728
Synonyms: GA_x6K02T2PMLR-5831021-5830086, MOR246-1P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258039
VEGA: 14
Homologene: 74224
Shisa5
Name: shisa family member 5
Synonyms: 2310008D10Rik, 6430628I05Rik, Scotin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66940
VEGA: 9
Homologene: 133951
Gm9966
Name: predicted gene 9966
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 10,153,654 bp
  • A to T, chromosome 1 at 72,277,310 bp
  • A to T, chromosome 1 at 83,257,276 bp
  • G to A, chromosome 2 at 20,854,998 bp
  • G to A, chromosome 2 at 35,283,953 bp
  • G to A, chromosome 2 at 35,315,965 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • A to T, chromosome 2 at 69,329,329 bp
  • A to G, chromosome 2 at 85,904,556 bp
  • C to A, chromosome 2 at 90,474,996 bp
  • C to T, chromosome 3 at 5,403,358 bp
  • A to G, chromosome 3 at 36,563,162 bp
  • A to G, chromosome 3 at 84,952,643 bp
  • A to T, chromosome 3 at 88,911,893 bp
  • T to C, chromosome 3 at 102,845,066 bp
  • A to T, chromosome 3 at 108,614,429 bp
  • C to T, chromosome 3 at 144,737,858 bp
  • A to G, chromosome 4 at 122,950,487 bp
  • T to A, chromosome 4 at 148,664,384 bp
  • T to A, chromosome 4 at 153,989,146 bp
  • A to G, chromosome 4 at 155,791,411 bp
  • T to C, chromosome 4 at 156,222,659 bp
  • T to G, chromosome 5 at 66,682,613 bp
  • A to G, chromosome 5 at 73,008,505 bp
  • A to G, chromosome 5 at 102,891,910 bp
  • T to C, chromosome 5 at 146,003,027 bp
  • C to A, chromosome 6 at 85,667,963 bp
  • T to C, chromosome 7 at 44,839,891 bp
  • A to C, chromosome 7 at 45,619,198 bp
  • A to G, chromosome 7 at 49,956,462 bp
  • T to C, chromosome 7 at 78,905,868 bp
  • C to T, chromosome 7 at 95,958,528 bp
  • T to C, chromosome 7 at 139,921,822 bp
  • G to T, chromosome 7 at 143,074,517 bp
  • A to G, chromosome 8 at 28,759,135 bp
  • A to G, chromosome 8 at 41,082,739 bp
  • A to T, chromosome 8 at 68,887,518 bp
  • A to T, chromosome 8 at 122,403,165 bp
  • A to G, chromosome 8 at 123,501,954 bp
  • G to A, chromosome 9 at 54,400,094 bp
  • T to C, chromosome 9 at 82,830,320 bp
  • A to T, chromosome 9 at 95,776,563 bp
  • G to A, chromosome 9 at 106,238,660 bp
  • T to C, chromosome 9 at 109,056,507 bp
  • G to A, chromosome 10 at 7,907,481 bp
  • T to A, chromosome 10 at 59,428,345 bp
  • G to A, chromosome 10 at 59,441,685 bp
  • G to A, chromosome 10 at 129,670,286 bp
  • G to A, chromosome 11 at 50,392,004 bp
  • T to A, chromosome 11 at 73,013,013 bp
  • T to C, chromosome 12 at 8,938,151 bp
  • T to C, chromosome 12 at 69,650,659 bp
  • T to C, chromosome 12 at 73,181,776 bp
  • C to T, chromosome 13 at 32,100,473 bp
  • T to A, chromosome 13 at 61,539,780 bp
  • T to A, chromosome 14 at 34,398,802 bp
  • T to C, chromosome 14 at 50,139,983 bp
  • T to C, chromosome 15 at 12,859,465 bp
  • T to C, chromosome 15 at 69,024,695 bp
  • C to A, chromosome 15 at 91,755,927 bp
  • T to C, chromosome 15 at 100,969,162 bp
  • T to C, chromosome 15 at 102,529,004 bp
  • T to C, chromosome 16 at 84,978,229 bp
  • G to A, chromosome 17 at 3,453,382 bp
  • G to A, chromosome 17 at 18,947,552 bp
  • A to G, chromosome 17 at 20,914,026 bp
  • A to G, chromosome 17 at 45,633,799 bp
  • A to T, chromosome 18 at 64,505,016 bp
  • A to G, chromosome 19 at 6,397,601 bp
  • A to G, chromosome 19 at 8,610,195 bp
  • G to T, chromosome 19 at 9,993,311 bp
  • T to A, chromosome 19 at 13,365,193 bp
  • T to C, chromosome 19 at 27,333,633 bp
  • A to T, chromosome 19 at 28,892,912 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2516 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040420-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.