Strain Name:
C57BL/6J-MtgxR3056Btlr/Mmmh
Stock Number:
040565-MU
Citation ID:
RRID:MMRRC_040565-MU
Other Names:
R3056 (G1), C57BL/6J-MtgxR3056Btlr
Major Collection:

Gene Information

Ltbp3
Name: latent transforming growth factor beta binding protein 3
Synonyms: Ltbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16998
VEGA: 19
HGNC: HGNC:6716
Homologene: 7405
Rictor
Name: RPTOR independent companion of MTOR, complex 2
Synonyms: 4921505C17Rik, 6030405M08Rik, D530039E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78757
VEGA: 15
Homologene: 34317
Mrpl20
Name: mitochondrial ribosomal protein L20
Synonyms: 2610008D01Rik, 4930425I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66448
Homologene: 9941
Fxr1
Name: fragile X mental retardation gene 1, autosomal homolog
Synonyms: 9530073J07Rik, 1110050J02Rik, Fxr1h, Fxr1p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14359
HGNC: HGNC:4023
Homologene: 3573
Bard1
Name: BRCA1 associated RING domain 1
Synonyms: ENSMUSG00000060893, ENSMUSG00000073653
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12021
HGNC: HGNC:952
Homologene: 400
Abca1
Name: ATP-binding cassette, sub-family A (ABC1), member 1
Synonyms: ABC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11303
HGNC: HGNC:29
Homologene: 21130
Ints12
Name: integrator complex subunit 12
Synonyms: A230056J18Rik, 2810027J24Rik, Phf22, 1110020M19Rik, 4930529N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71793
Homologene: 32474
C6
Name: complement component 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12274
HGNC: HGNC:1339
Homologene: 47
Xrcc4
Name: X-ray repair complementing defective repair in Chinese hamster cells 4
Synonyms: 2310057B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 108138
Homologene: 2555
Tnks1bp1
Name: tankyrase 1 binding protein 1
Synonyms: TAB182
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228140
Homologene: 14117
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54403
Homologene: 55776
Peg10
Name: paternally expressed 10
Synonyms: Rtl2, Mart2, Edr, MyEF-3 like, MyEF-3, HB-1, MEF3L, Mar2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 170676
Homologene: 116067
Nlgn1
Name: neuroligin 1
Synonyms: Nlg1, 6330415N05Rik, NL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 192167
Homologene: 56690
Fat3
Name: FAT atypical cadherin 3
Synonyms: 9430076A06Rik, D430038H04Rik, LOC382129, LOC234973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Vmn2r110
Name: vomeronasal 2, receptor 110
Synonyms: EG224582
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224582
Homologene: 129678
Epas1
Name: endothelial PAS domain protein 1
Synonyms: hypoxia inducible transcription factor 2alpha, bHLHe73, HRF, HLF, HIF2A, HIF-2alpha, MOP2, Hif like protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13819
VEGA: 17
HGNC: HGNC:3374
Homologene: 1095
Timm29
Name: translocase of inner mitochondrial membrane 29
Synonyms: 1810026J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69773
Homologene: 34702
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78016
Homologene: 15814
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 268527
Homologene: 8780
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 435626
Homologene: 52359
Tctn2
Name: tectonic family member 2
Synonyms: 4432405B04Rik, Tect2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67978
Homologene: 11729
Tnfrsf8
Name: tumor necrosis factor receptor superfamily, member 8
Synonyms: CD30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21941
Homologene: 949
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Wiz
Name: widely-interspaced zinc finger motifs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22404
Homologene: 7997
Catsper3
Name: cation channel, sperm associated 3
Synonyms: 4921522D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76856
Homologene: 12658
Cntn5
Name: contactin 5
Synonyms: 6720426O10Rik, A830025P08Rik, LOC244683, NB-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
A830018L16Rik
Name: RIKEN cDNA A830018L16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320492
Homologene: 14194
Aadacl4fm4
Name: AADACL4 family member 4
Synonyms: Gm436, LOC230890
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230890
Homologene: 135765
Cxcr6
Name: chemokine (C-X-C motif) receptor 6
Synonyms: STRL33, BONZO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80901
VEGA: 9
Homologene: 38197
Pccb
Name: propionyl Coenzyme A carboxylase, beta polypeptide
Synonyms: 1300012P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66904
HGNC: HGNC:8654
Homologene: 447
Utp14b
Name: UTP14B small subunit processome component
Synonyms: jsd, 4932411L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 195434
Homologene: 78703
Pttg1ip2
Name: PTTG1IP family member 2
Synonyms: LOC381716, 1700015F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381716
Homologene: 136447
Asb14
Name: ankyrin repeat and SOCS box-containing 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 142687
Homologene: 15445
Olfr1163
Name: olfactory receptor 1163
Synonyms: GA_x6K02T2Q125-49563265-49562315, MOR174-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258638
Homologene: 17328
Olfr1087
Name: olfactory receptor 1087
Synonyms: GA_x6K02T2Q125-48182406-48181465, MOR188-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258843
Gpatch11
Name: G patch domain containing 11
Synonyms: Ccdc75, 2310002B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 53951
VEGA: 17
Homologene: 44687
Tmem92
Name: transmembrane protein 92
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544806
Homologene: 136274
Lmx1b
Name: LIM homeobox transcription factor 1 beta
Synonyms: Icst, LMX1.2, GENA 191
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16917
HGNC: HGNC:6654
Homologene: 55648
Micos13
Name: mitochondrial contact site and cristae organizing system subunit 13
Synonyms: 2410015M20Rik, QIL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224904
VEGA: 17
Homologene: 17699
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 11,933,601 bp
  • A to G, chromosome 1 at 46,268,709 bp
  • A to G, chromosome 1 at 54,288,842 bp
  • A to G, chromosome 1 at 71,088,231 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • T to A, chromosome 1 at 78,664,725 bp
  • G to A, chromosome 2 at 33,567,285 bp
  • T to A, chromosome 2 at 85,070,000 bp
  • C to A, chromosome 2 at 86,690,552 bp
  • T to A, chromosome 2 at 88,071,239 bp
  • T to C, chromosome 3 at 25,433,696 bp
  • A to G, chromosome 3 at 34,049,184 bp
  • G to A, chromosome 3 at 133,109,365 bp
  • A to T, chromosome 4 at 53,127,626 bp
  • A to G, chromosome 4 at 144,674,698 bp
  • C to T, chromosome 4 at 145,285,325 bp
  • G to T, chromosome 4 at 155,803,872 bp
  • A to T, chromosome 5 at 5,457,283 bp
  • T to C, chromosome 5 at 89,225,948 bp
  • T to A, chromosome 5 at 124,627,144 bp
  • G to A, chromosome 6 at 4,755,029 bp
  • A to G, chromosome 9 at 10,419,071 bp
  • C to T, chromosome 9 at 15,960,496 bp
  • T to C, chromosome 9 at 21,593,591 bp
  • C to T, chromosome 9 at 101,030,197 bp
  • A to T, chromosome 9 at 123,810,464 bp
  • C to T, chromosome 11 at 94,779,047 bp
  • G to T, chromosome 12 at 16,688,591 bp
  • T to C, chromosome 13 at 55,808,896 bp
  • T to C, chromosome 13 at 90,062,077 bp
  • A to G, chromosome 14 at 26,914,189 bp
  • T to C, chromosome 15 at 4,739,873 bp
  • G to A, chromosome 15 at 6,778,231 bp
  • T to A, chromosome 17 at 20,583,098 bp
  • A to G, chromosome 17 at 32,357,697 bp
  • A to G, chromosome 17 at 56,608,889 bp
  • A to G, chromosome 17 at 78,843,843 bp
  • T to C, chromosome 17 at 86,830,981 bp
  • C to A, chromosome 19 at 5,751,406 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3056 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040565-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.