Strain Name:
C57BL/6J-MtgxR3160Btlr/Mmmh
Stock Number:
040611-MU
Citation ID:
RRID:MMRRC_040611-MU
Other Names:
R3160 (G1), C57BL/6J-MtgxR3160Btlr
Major Collection:

Gene Information

Adcy9
Name: adenylate cyclase 9
Synonyms: D16Wsu65e, ACtp10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11515
HGNC: HGNC:240
Homologene: 868
Iqgap1
Name: IQ motif containing GTPase activating protein 1
Synonyms: D7Ertd237e, D7Ertd257e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 29875
HGNC: HGNC:6110
Homologene: 74514
Camk1g
Name: calcium/calmodulin-dependent protein kinase I gamma
Synonyms: CLICK-III, CaMKIgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215303
Homologene: 48706
Usp32
Name: ubiquitin specific peptidase 32
Synonyms: 6430526O11Rik, 2900074J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237898
Homologene: 13066
Yeats2
Name: YEATS domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208146
VEGA: 16
Homologene: 9967
Ptprg
Name: protein tyrosine phosphatase, receptor type, G
Synonyms: 5430405N12Rik, RPTPgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19270
HGNC: HGNC:9671
Homologene: 2129
Srbd1
Name: S1 RNA binding domain 1
Synonyms: D530025C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78586
VEGA: 17
Homologene: 9994
Naa25
Name: N(alpha)-acetyltransferase 25, NatB auxiliary subunit
Synonyms: 4833422K13Rik, C330023M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231713
Homologene: 6891
Urb1
Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Synonyms: 5730405K23Rik, 4921511H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207932
Homologene: 45941
Copa
Name: coatomer protein complex subunit alpha
Synonyms: xenin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12847
HGNC: HGNC:2230
Homologene: 3218
Cep350
Name: centrosomal protein 350
Synonyms: 6430546F08Rik, 4933409L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74081
Homologene: 8879
Mnat1
Name: menage a trois 1
Synonyms: MAT1, E130115E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17420
HGNC: HGNC:7181
Homologene: 1821
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, Tulip1, 2310003F20Rik, Garnl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: 2310001H13Rik, hyrt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67095
Homologene: 25103
Msh6
Name: mutS homolog 6
Synonyms: Msh6, GTBP, Gtmbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17688
VEGA: 17
HGNC: HGNC:7329
Homologene: 149
Nop2
Name: NOP2 nucleolar protein
Synonyms: 120kDa, Nol1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 110109
HGNC: HGNC:7867
Homologene: 135865
Hnrnpu
Name: heterogeneous nuclear ribonucleoprotein U
Synonyms: scaffold attachment factor A, Sp120, Hnrpu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 51810
HGNC: HGNC:5048
Homologene: 22991
Dnajc13
Name: DnaJ heat shock protein family (Hsp40) member C13
Synonyms: Rme8, LOC382100, D030002L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235567
Homologene: 13574
Dennd1c
Name: DENN/MADD domain containing 1C
Synonyms: 4432409M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70785
VEGA: 17
Homologene: 11773
Ccdc181
Name: coiled-coil domain containing 181
Synonyms: 4930455F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74895
Homologene: 10912
Irak2
Name: interleukin-1 receptor-associated kinase 2
Synonyms: 6330415L08Rik, IRAK-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108960
HGNC: HGNC:6113
Homologene: 1207
Tns2
Name: tensin 2
Synonyms: nep, nph, Tenc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Srgap3
Name: SLIT-ROBO Rho GTPase activating protein 3
Synonyms: Arhgap14, D130026O08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 259302
Homologene: 56686
Pde5a
Name: phosphodiesterase 5A, cGMP-specific
Synonyms: PDE5A1, Pde5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242202
HGNC: HGNC:8784
Homologene: 842
Itgb2l
Name: integrin beta 2-like
Synonyms: pactolus, 5033406G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16415
Tuba8
Name: tubulin, alpha 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53857
Homologene: 56766
Prss59
Name: protease, serine 59
Synonyms: Tryx5, 1700074P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73481
Homologene: 49905
Vmn1r48
Name: vomeronasal 1 receptor 48
Synonyms: V1ra3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113845
Homologene: 137651
Tulp4
Name: tubby like protein 4
Synonyms: 1110057P05Rik, 2210038L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68842
Homologene: 32467
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: EGF-TM7, D17Ertd479e, FIRE, Gpr127, Emr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52614
VEGA: 17
Homologene: 64640
Topaz1
Name: testis and ovary specific PAZ domain containing 1
Synonyms: Gm9524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 671232
VEGA: 9
Homologene: 19835
0610040J01Rik
Name: RIKEN cDNA 0610040J01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76261
Homologene: 49537
Myo18b
Name: myosin XVIIIb
Synonyms: 4932408L24Rik, 4933411E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74376
Homologene: 53435
Obsl1
Name: obscurin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98733
Epsti1
Name: epithelial stromal interaction 1 (breast)
Synonyms: 5033415K03Rik, BRESI1, 2310046K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 108670
VEGA: 14
Homologene: 12630
Zfp598
Name: zinc finger protein 598
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 213753
VEGA: 17
Homologene: 5672
Vmn2r117
Name: vomeronasal 2, receptor 117
Synonyms: EG619788, V2Rp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 619788
Homologene: 86604
Amer2
Name: APC membrane recruitment 2
Synonyms: 2600011E07Rik, Amer2, Fam123a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 72125
VEGA: 14
Homologene: 45141
Olfr1263
Name: olfactory receptor 1263
Synonyms: GA_x6K02T2Q125-51447049-51447969, MOR234-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258790
Homologene: 45043
Dapk2
Name: death-associated protein kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13143
HGNC: HGNC:2675
Homologene: 74940
Serinc2
Name: serine incorporator 2
Synonyms: FKSG84, TDE2, 2310004K20Rik, Tde2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230779
Homologene: 27797
Cdc14b
Name: CDC14 cell division cycle 14B
Synonyms: 2810432N10Rik, A530086E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218294
VEGA: 13
HGNC: HGNC:1719
Homologene: 104197
Olfr739
Name: olfactory receptor 739
Synonyms: GA_x6K02T2PMLR-6121675-6122604, MOR106-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258663
Homologene: 121549
Crbn
Name: cereblon
Synonyms: 2610203G15Rik, 2900045O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58799
Homologene: 9461
Decr1
Name: 2,4-dienoyl CoA reductase 1, mitochondrial
Synonyms: Decr, Nadph, 1200012F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67460
HGNC: HGNC:2753
Homologene: 68178
Olfr30
Name: olfactory receptor 30
Synonyms: MTPCR07, MOR281-1, GA_x6K02T2NKPP-957001-957948
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18329
Homologene: 131139
Btnl2
Name: butyrophilin-like 2
Synonyms: butyrophylin-like MHC class II associated, BTL-II, NG9, BTLN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 547431
HGNC: HGNC:1142
Homologene: 10482
Gm7337
Name: predicted gene 7337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 654494
Socs5
Name: suppressor of cytokine signaling 5
Synonyms: Cish5, SOCS-5, 1810018L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56468
VEGA: 17
Homologene: 10495
Disp1
Name: dispatched RND transporter family member 1
Synonyms: DispA, 1190008H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68897
Homologene: 14133
Vstm5
Name: V-set and transmembrane domain containing 5
Synonyms: 2200002K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69137
VEGA: 9
Homologene: 45982
Olfr156
Name: olfactory receptor 156
Synonyms: OR37B, mOR37b, Olfr37b, MOR262-6, GA_x6K02T2N78B-16125144-16126100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 29846
Homologene: 133652
Mill2
Name: MHC I like leukocyte 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243864
HGNC: HGNC:7091
Homologene: 88329
Mmp7
Name: matrix metallopeptidase 7
Synonyms: matrilysin, MAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17393
HGNC: HGNC:7174
Homologene: 37619
Rps2
Name: ribosomal protein S2
Synonyms: Rps2, Llrep3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16898
Homologene: 37714
Mlf1
Name: myeloid leukemia factor 1
Synonyms: HLS7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17349
HGNC: HGNC:7125
Homologene: 7839
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 75,491,082 bp
  • T to C, chromosome 1 at 155,863,164 bp
  • T to A, chromosome 1 at 164,280,296 bp
  • T to A, chromosome 1 at 172,091,233 bp
  • T to C, chromosome 1 at 178,331,125 bp
  • T to C, chromosome 1 at 183,087,242 bp
  • T to C, chromosome 1 at 193,359,807 bp
  • T to G, chromosome 2 at 90,015,021 bp
  • T to C, chromosome 3 at 67,384,539 bp
  • T to A, chromosome 3 at 122,781,628 bp
  • T to A, chromosome 4 at 15,930,972 bp
  • T to A, chromosome 4 at 43,820,544 bp
  • A to G, chromosome 4 at 130,260,735 bp
  • T to C, chromosome 5 at 63,896,490 bp
  • A to C, chromosome 5 at 87,851,557 bp
  • A to C, chromosome 5 at 112,692,728 bp
  • A to G, chromosome 5 at 121,435,072 bp
  • A to G, chromosome 6 at 40,926,069 bp
  • G to A, chromosome 6 at 90,036,378 bp
  • T to C, chromosome 6 at 106,790,866 bp
  • A to G, chromosome 6 at 112,729,658 bp
  • G to T, chromosome 6 at 113,672,760 bp
  • A to G, chromosome 6 at 121,222,738 bp
  • A to G, chromosome 6 at 125,134,592 bp
  • A to C, chromosome 7 at 18,856,174 bp
  • G to A, chromosome 7 at 80,752,338 bp
  • T to A, chromosome 9 at 7,696,189 bp
  • T to G, chromosome 9 at 15,257,298 bp
  • T to G, chromosome 9 at 66,254,611 bp
  • G to T, chromosome 9 at 104,219,898 bp
  • C to T, chromosome 9 at 121,451,734 bp
  • T to C, chromosome 9 at 122,749,381 bp
  • T to C, chromosome 11 at 58,455,227 bp
  • A to G, chromosome 11 at 85,025,536 bp
  • A to T, chromosome 12 at 55,709,586 bp
  • G to A, chromosome 12 at 73,179,321 bp
  • A to G, chromosome 13 at 64,246,608 bp
  • T to A, chromosome 14 at 12,091,192 bp
  • T to A, chromosome 14 at 50,425,031 bp
  • A to G, chromosome 14 at 60,378,551 bp
  • A to T, chromosome 14 at 77,974,513 bp
  • A to G, chromosome 15 at 102,113,336 bp
  • A to G, chromosome 16 at 4,311,588 bp
  • T to C, chromosome 16 at 20,193,645 bp
  • A to G, chromosome 16 at 90,797,903 bp
  • A to G, chromosome 16 at 96,437,389 bp
  • A to G, chromosome 17 at 6,198,708 bp
  • A to G, chromosome 17 at 23,460,378 bp
  • T to C, chromosome 17 at 24,678,725 bp
  • G to T, chromosome 17 at 24,720,978 bp
  • T to C, chromosome 17 at 34,358,065 bp
  • T to C, chromosome 17 at 55,802,218 bp
  • C to T, chromosome 17 at 57,066,562 bp
  • A to T, chromosome 17 at 86,130,215 bp
  • A to T, chromosome 17 at 87,134,718 bp
  • T to C, chromosome 17 at 87,985,481 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3160 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040611-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.