Strain Name:
C57BL/6J-MtgxR3872Btlr/Mmmh
Stock Number:
040790-MU
Citation ID:
RRID:MMRRC_040790-MU
Other Names:
R3872 (G1), C57BL/6J-MtgxR3872Btlr
Major Collection:

Gene Information

Vps33a
Name: VPS33A CORVET/HOPS core subunit
Synonyms: bf, 3830421M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77573
Homologene: 11294
Epha2
Name: Eph receptor A2
Synonyms: Sek-2, Eck, Sek2, Myk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13836
HGNC: HGNC:3386
Homologene: 20929
Dlx5
Name: distal-less homeobox 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13395
HGNC: HGNC:2918
Homologene: 3825
Plin3
Name: perilipin 3
Synonyms: 1300012C15Rik, Tip47, M6prbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66905
VEGA: 17
Homologene: 4247
Dlgap4
Name: DLG associated protein 4
Synonyms: WBP16, SAP90/PSD-95-associated protein 4, PSD-95/SAP90 binding protein 4, DAP4, Sapap4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228836
Homologene: 8935
Plxna1
Name: plexin A1
Synonyms: NOV, Plxn1, 2600013D04Rik, PlexA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18844
HGNC: HGNC:9099
Homologene: 56426
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Tip5, Walp3, C030005G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Cry1
Name: cryptochrome 1 (photolyase-like)
Synonyms: Phll1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12952
VEGA: 10
HGNC: HGNC:2384
Homologene: 7042
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57752
Homologene: 5087
Akap12
Name: A kinase (PRKA) anchor protein (gravin) 12
Synonyms: SSeCKS, Tsga12, Srcs5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 83397
VEGA: 10
HGNC: HGNC:370
Homologene: 3740
Fbxo21
Name: F-box protein 21
Synonyms: 2810425J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231670
Homologene: 14145
Epcam
Name: epithelial cell adhesion molecule
Synonyms: Ep-CAM, panepithelial glycoprotein 314, GA733-2, TROP1, Ly74, Egp314, EpCAM, gp40, CD326, EGP-2, Tacstd1, EpCAM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17075
VEGA: 17
Homologene: 1764
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17847
Homologene: 40978
Scfd1
Name: Sec1 family domain containing 1
Synonyms: 3110021P21Rik, STXBP1L2, RA410
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76983
VEGA: 12
Homologene: 5650
Rnf17
Name: ring finger protein 17
Synonyms: MMIP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 30054
VEGA: 14
Homologene: 23727
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71722
Homologene: 87637
Car12
Name: carbonic anhydrase 12
Synonyms: 2310047E01Rik, CA XII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76459
HGNC: HGNC:1371
Homologene: 20327
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: 4432409B16Rik, Sofa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Itpa
Name: inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Synonyms: Itp, 2010016I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16434
HGNC: HGNC:6176
Homologene: 6289
BC055324
Name: cDNA sequence BC055324
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381306
Homologene: 10058
Tdo2
Name: tryptophan 2,3-dioxygenase
Synonyms: TDO, TO, chky
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56720
Homologene: 4132
Septin5
Name: septin 5
Synonyms: Pnutl1, Cdcrel1, Sept5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 18951
VEGA: 16
HGNC: HGNC:9164
Homologene: 74446
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1154Clo, b2b1134Clo, b2b1537Clo, b2b1565Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Klhl1
Name: kelch-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 93688
HGNC: HGNC:6352
Homologene: 56903
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Myo1g
Name: myosin IG
Synonyms: E430002D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246177
Homologene: 27996
Krt34
Name: keratin 34
Synonyms: 4733401E01Rik, Krt1-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16672
HGNC: HGNC:6452
Homologene: 31083
Mroh2b
Name: maestro heat-like repeat family member 2B
Synonyms: 4930455B06Rik, Heatr7b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223825
VEGA: 15
Homologene: 128807
Olfr1310
Name: olfactory receptor 1310
Synonyms: GA_x6K02T2Q125-73056609-73055671, MOR245-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258441
Homologene: 74053
Col19a1
Name: collagen, type XIX, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12823
HGNC: HGNC:2196
Homologene: 55608
Stk35
Name: serine/threonine kinase 35
Synonyms: CLP-36 interacting kinase, CLIK1, 1700054C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67333
Homologene: 15441
Dpp6
Name: dipeptidylpeptidase 6
Synonyms: Dpp-6, Peplb, In(5)6H-p, Rw, LOC384168, B930011P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13483
HGNC: HGNC:3010
Homologene: 22560
Cabcoco1
Name: ciliary associated calcium binding coiled-coil 1
Synonyms: 1700040L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73287
Homologene: 12495
Hecw2
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms: D030049F17Rik, Nedl2, A730039N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329152
Homologene: 66192
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50720
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68553
Homologene: 130754
Aatk
Name: apoptosis-associated tyrosine kinase
Synonyms: AATYK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11302
HGNC: HGNC:21
Homologene: 74861
Abca5
Name: ATP-binding cassette, sub-family A (ABC1), member 5
Synonyms: ABC13, B930033A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Krt26
Name: keratin 26
Synonyms: 4732407F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 320864
Homologene: 37118
Dsc3
Name: desmocollin 3
Synonyms: 5430426I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13507
VEGA: 18
HGNC: HGNC:3037
Homologene: 1462
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67607
Homologene: 137363
Olfr1156
Name: olfactory receptor 1156
Synonyms: GA_x6K02T2Q125-49433499-49432537, MOR174-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258814
HGNC: HGNC:8351
Homologene: 72031
Vmn2r60
Name: vomeronasal 2, receptor 60
Synonyms: Casr-rs3, EG637898, Gprc2a-rs3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637898
Homologene: 129683
Iqca
Name: IQ motif containing with AAA domain
Synonyms: 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74918
Homologene: 49784
Bhmt-ps1
Name: betaine-homocysteine methyltransferase, pseudogene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 57421
Eya4
Name: EYA transcriptional coactivator and phosphatase 4
Synonyms: B130023L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14051
VEGA: 10
HGNC: HGNC:3522
Homologene: 3025
Sod3
Name: superoxide dismutase 3, extracellular
Synonyms: EC-SOD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20657
Homologene: 2334
Sgsh
Name: N-sulfoglucosamine sulfohydrolase (sulfamidase)
Synonyms: sulphamidase, 4632406A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27029
Homologene: 167
Septin1
Name: septin 1
Synonyms: PNUTL3, Diff6, Sept1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54204
HGNC: HGNC:2879
Homologene: 23009
Phb2
Name: prohibitin 2
Synonyms: Bap37, Bcap37, repressor of estrogen receptor activity, REA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12034
Homologene: 5263
Msmo1
Name: methylsterol monoxygenase 1
Synonyms: ERG25, DESP4, 1500001G16Rik, C78600, Sc4mol
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66234
Homologene: 133932
Slc35f1
Name: solute carrier family 35, member F1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215085
Homologene: 33552
Igfals
Name: insulin-like growth factor binding protein, acid labile subunit
Synonyms: ALS, Albs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16005
VEGA: 17
HGNC: HGNC:5468
Homologene: 37987
CAAA01083517.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Olfr101
Name: olfactory receptor 101
Synonyms: MOR250-2, GA_x6K02T2PSCP-1761617-1760691
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258831
HGNC: HGNC:8178
Homologene: 133728
Frg2f1
Name: FSHD region gene 2 family member 1
Synonyms: AA415398
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433752
Homologene: 86332
CT030687.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Tmem150b
Name: transmembrane protein 150B
Synonyms: Tmem224
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330460
Homologene: 19603
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 24,575,327 bp
  • A to T, chromosome 1 at 53,832,757 bp
  • A to T, chromosome 1 at 90,089,481 bp
  • A to T, chromosome 1 at 163,986,964 bp
  • T to C, chromosome 1 at 183,356,998 bp
  • T to A, chromosome 2 at 87,949,530 bp
  • T to C, chromosome 2 at 112,008,323 bp
  • T to C, chromosome 2 at 129,810,575 bp
  • T to G, chromosome 2 at 130,681,010 bp
  • T to C, chromosome 2 at 156,749,347 bp
  • T to C, chromosome 3 at 81,968,086 bp
  • T to C, chromosome 4 at 26,369,201 bp
  • T to A, chromosome 4 at 119,530,958 bp
  • T to C, chromosome 4 at 141,308,405 bp
  • A to G, chromosome 5 at 27,721,058 bp
  • A to G, chromosome 5 at 52,368,289 bp
  • G to A, chromosome 5 at 118,000,329 bp
  • C to T, chromosome 5 at 123,531,192 bp
  • G to T, chromosome 6 at 6,878,209 bp
  • C to A, chromosome 6 at 89,332,692 bp
  • G to A, chromosome 6 at 124,716,431 bp
  • A to T, chromosome 7 at 4,724,361 bp
  • T to C, chromosome 7 at 25,271,699 bp
  • T to A, chromosome 7 at 41,649,444 bp
  • C to T, chromosome 7 at 42,136,454 bp
  • T to C, chromosome 7 at 127,215,275 bp
  • C to T, chromosome 7 at 130,622,422 bp
  • T to C, chromosome 7 at 141,640,600 bp
  • C to T, chromosome 8 at 64,722,463 bp
  • C to A, chromosome 9 at 66,717,552 bp
  • T to C, chromosome 9 at 106,013,659 bp
  • G to A, chromosome 10 at 4,357,590 bp
  • A to T, chromosome 10 at 23,155,972 bp
  • A to G, chromosome 10 at 53,021,910 bp
  • T to C, chromosome 10 at 68,516,278 bp
  • T to C, chromosome 10 at 85,133,160 bp
  • T to A, chromosome 10 at 128,124,110 bp
  • C to T, chromosome 11 at 6,514,886 bp
  • C to T, chromosome 11 at 23,489,033 bp
  • T to C, chromosome 11 at 69,000,263 bp
  • A to G, chromosome 11 at 69,429,348 bp
  • T to C, chromosome 11 at 99,334,744 bp
  • T to C, chromosome 11 at 100,041,417 bp
  • T to A, chromosome 11 at 110,310,233 bp
  • A to G, chromosome 11 at 119,350,947 bp
  • T to C, chromosome 11 at 120,010,219 bp
  • A to G, chromosome 12 at 51,392,196 bp
  • T to C, chromosome 12 at 88,249,706 bp
  • G to T, chromosome 14 at 56,475,413 bp
  • C to T, chromosome 14 at 61,148,068 bp
  • A to G, chromosome 14 at 96,518,179 bp
  • A to T, chromosome 15 at 4,925,061 bp
  • A to G, chromosome 15 at 28,411,510 bp
  • A to G, chromosome 16 at 18,622,973 bp
  • G to A, chromosome 17 at 24,881,605 bp
  • T to A, chromosome 17 at 37,299,979 bp
  • A to G, chromosome 17 at 56,284,181 bp
  • C to A, chromosome 17 at 87,639,926 bp
  • C to A, chromosome 18 at 19,971,508 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3872 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040790-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.