Strain Name:
C57BL/6J-MtgxR3956Btlr/Mmmh
Stock Number:
040833-MU
Citation ID:
RRID:MMRRC_040833-MU
Other Names:
R3956 (G1), C57BL/6J-MtgxR3956Btlr
Major Collection:

Gene Information

Mtmr3
Name: myotubularin related protein 3
Synonyms: ZFYVE10, 1700092A20Rik, FYVE-DSP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74302
HGNC: HGNC:7451
Homologene: 23662
Lmf1
Name: lipase maturation factor 1
Synonyms: 2400010G15Rik, Tmem112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76483
Homologene: 23384
Cyrib
Name: CYFIP related Rac1 interactor B
Synonyms: Fam49b, 0910001A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223601
VEGA: 15
Homologene: 9599
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 9530077A04Rik, 1810033J14Rik, D230038D11Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69188
Homologene: 18822
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77595
Homologene: 28122
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 321003
Sar1a
Name: secretion associated Ras related GTPase 1A
Synonyms: 1600019H17Rik, Sara1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20224
VEGA: 10
Homologene: 90897
Stim2
Name: stromal interaction molecule 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 116873
Homologene: 32490
Gfod1
Name: glucose-fructose oxidoreductase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 328232
VEGA: 13
Homologene: 49581
Ric1
Name: RAB6A GEF complex partner 1
Synonyms: C030046E11Rik, C130057E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226089
Homologene: 13806
Ccni
Name: cyclin I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12453
HGNC: HGNC:1595
Homologene: 4979
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Robo2
Name: roundabout guidance receptor 2
Synonyms: 9430089E08Rik, D230004I22Rik, 2600013A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268902
Homologene: 43188
B3gat1
Name: beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
Synonyms: 0710007K08Rik, GlcAT-P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76898
HGNC: HGNC:921
Homologene: 49551
Fkbp8
Name: FK506 binding protein 8
Synonyms: Fkbp38, 38kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14232
HGNC: HGNC:3724
Homologene: 7720
Creld1
Name: cysteine-rich with EGF-like domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171508
Homologene: 32265
Riok3
Name: RIO kinase 3
Synonyms: Sudd, D18Ertd331e, 1200013N13Rik, E130306C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 66878
VEGA: 18
Homologene: 2843
Aagab
Name: alpha- and gamma-adaptin binding protein
Synonyms: 2310007F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66939
VEGA: 9
Homologene: 11648
Tmem131l
Name: transmembrane 131 like
Synonyms: D930015E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229473
Homologene: 9057
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233810
Homologene: 132942
Ackr4
Name: atypical chemokine receptor 4
Synonyms: CCBP2, CCR11, A630091E18Rik, CCX-CKR, Ccrl1, PPR1, VSHK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 252837
HGNC: HGNC:1611
Homologene: 49474
Ttn
Name: titin
Synonyms: D830007G01Rik, 2310036G12Rik, 1100001C23Rik, L56, D330041I19Rik, connectin, mdm, shru, 2310074I15Rik, 2310057K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Efhc1
Name: EF-hand domain (C-terminal) containing 1
Synonyms: mRib72-1, myoclonin1, 1700029F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71877
Homologene: 10003
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnahc2, Dnhd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: RGC2, AS250, A230067G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241694
Homologene: 28131
Clspn
Name: claspin
Synonyms: E130314M08Rik, C85083
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269582
Homologene: 11138
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: E430001K23Rik, 2900055E17Rik, Dagk3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Acsl1
Name: acyl-CoA synthetase long-chain family member 1
Synonyms: Facl2, Acas1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14081
HGNC: HGNC:3569
Homologene: 37561
Pmfbp1
Name: polyamine modulated factor 1 binding protein 1
Synonyms: F77, 1700016D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56523
Homologene: 23182
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52020
VEGA: 17
Homologene: 45466
2210016F16Rik
Name: RIKEN cDNA 2210016F16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 70153
Homologene: 13005
Tbc1d9
Name: TBC1 domain family, member 9
Synonyms: 4933431N12Rik, C76116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71310
Homologene: 57079
Sgcz
Name: sarcoglycan zeta
Synonyms: C230085N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244431
Homologene: 26726
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 268527
Homologene: 8780
Olfr1042
Name: olfactory receptor 1042
Synonyms: GA_x6K02T2Q125-47629317-47628376, MOR185-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257941
Homologene: 133665
Adam2
Name: a disintegrin and metallopeptidase domain 2
Synonyms: fertilin beta, Ftnb, Ph30-beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11495
VEGA: 14
HGNC: HGNC:198
Homologene: 1127
Abca5
Name: ATP-binding cassette, sub-family A (ABC1), member 5
Synonyms: B930033A02Rik, ABC13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Mfsd2b
Name: major facilitator superfamily domain containing 2B
Synonyms: Gm1964
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 432628
Homologene: 47753
Sema5a
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Synonyms: 9130201M22Rik, M-Sema D, Semaf, semF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20356
VEGA: 15
Homologene: 2949
9330159F19Rik
Name: RIKEN cDNA 9330159F19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 212448
VEGA: 10
Homologene: 8804
Rsbn1
Name: rosbin, round spermatid basic protein 1
Synonyms: C230004D03Rik, Rsbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229675
Homologene: 10154
Evi5l
Name: ecotropic viral integration site 5 like
Synonyms: 2310039H16Rik, B130050I23Rik, 1700084G18Rik, 3110007G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 213027
Homologene: 134635
BC051076
Name: cDNA sequence BC051076
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243090
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: 4931400F03Rik, eb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74053
Homologene: 12938
Klk14
Name: kallikrein related-peptidase 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 317653
HGNC: HGNC:6362
Homologene: 69348
Veph1
Name: ventricular zone expressed PH domain-containing 1
Synonyms: 2810471M23Rik, Veph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72789
Homologene: 11624
Gm8882
Name: predicted gene 8882
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 667929
Tlcd5
Name: TLC domain containing 5
Synonyms: LOC235300, Tmem136
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235300
VEGA: 9
Homologene: 72560
Gm960
Name: predicted gene 960
Synonyms: Top6bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 381196
VEGA: 19
Homologene: 69381
Rasgrf2
Name: RAS protein-specific guanine nucleotide-releasing factor 2
Synonyms: 6330417G04Rik, Grf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19418
HGNC: HGNC:9876
Homologene: 2169
Olfr1039
Name: olfactory receptor 1039
Synonyms: MOR185-5, GA_x6K02T2Q125-47600809-47599850, MOR185-5, Olfr1517, MOR185-9P, MOR185-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257950
Homologene: 79382
Dipk1b
Name: divergent protein kinase domain 1B
Synonyms: PIP49, Fam69b, B230317C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56279
Homologene: 10516
Olfr199
Name: olfactory receptor 199
Synonyms: MOR182-14, GA_x54KRFPKG5P-55430495-55429569
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 404310
Homologene: 37011
Ptgir
Name: prostaglandin I receptor (IP)
Synonyms: prostacyclin receptor, IP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19222
HGNC: HGNC:9602
Homologene: 7496
Hbq1a
Name: hemoglobin, theta 1A
Synonyms: A230090E05Rik, Hbq1, LOC380691
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216635
HGNC: HGNC:4833
Ccnq
Name: cyclin Q
Synonyms: 1810009O10Rik, cyclin M, Fam58b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69109
Homologene: 13362
Tex37
Name: testis expressed 37
Synonyms: 1700011F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74221
Homologene: 17643
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 20,978,666 bp
  • C to T, chromosome 2 at 26,635,567 bp
  • C to T, chromosome 2 at 52,201,963 bp
  • A to G, chromosome 2 at 76,969,249 bp
  • C to T, chromosome 2 at 86,131,019 bp
  • A to G, chromosome 2 at 86,159,938 bp
  • C to T, chromosome 2 at 146,435,964 bp
  • A to G, chromosome 3 at 66,172,196 bp
  • C to A, chromosome 3 at 83,910,419 bp
  • A to T, chromosome 3 at 90,193,054 bp
  • A to G, chromosome 3 at 103,928,675 bp
  • ACGGCGGCGGC to A, chromosome 4 at 126,566,437 bp
  • A to G, chromosome 5 at 23,496,025 bp
  • G to T, chromosome 5 at 54,110,859 bp
  • A to G, chromosome 5 at 87,964,251 bp
  • A to G, chromosome 5 at 93,183,404 bp
  • A to G, chromosome 6 at 70,913,485 bp
  • A to G, chromosome 6 at 113,492,229 bp
  • G to T, chromosome 6 at 132,361,851 bp
  • A to G, chromosome 7 at 16,906,869 bp
  • G to A, chromosome 7 at 43,692,077 bp
  • A to G, chromosome 7 at 120,527,752 bp
  • T to C, chromosome 8 at 4,191,358 bp
  • A to G, chromosome 8 at 37,526,192 bp
  • T to A, chromosome 8 at 46,534,458 bp
  • T to G, chromosome 8 at 70,534,867 bp
  • C to T, chromosome 8 at 83,233,532 bp
  • A to G, chromosome 8 at 109,530,169 bp
  • A to G, chromosome 9 at 26,757,028 bp
  • C to A, chromosome 9 at 43,111,513 bp
  • A to G, chromosome 9 at 63,619,160 bp
  • A to G, chromosome 9 at 104,086,152 bp
  • A to G, chromosome 10 at 29,224,809 bp
  • A to T, chromosome 10 at 61,686,393 bp
  • A to T, chromosome 10 at 119,930,026 bp
  • A to T, chromosome 11 at 4,491,138 bp
  • T to C, chromosome 11 at 32,300,214 bp
  • T to A, chromosome 11 at 69,484,021 bp
  • C to A, chromosome 11 at 78,751,023 bp
  • T to A, chromosome 11 at 110,293,929 bp
  • A to T, chromosome 12 at 4,866,848 bp
  • G to T, chromosome 12 at 16,682,299 bp
  • A to T, chromosome 13 at 43,201,062 bp
  • A to G, chromosome 13 at 58,384,389 bp
  • A to G, chromosome 13 at 91,982,855 bp
  • G to A, chromosome 14 at 66,057,610 bp
  • T to C, chromosome 15 at 32,568,699 bp
  • T to C, chromosome 15 at 63,941,974 bp
  • A to G, chromosome 15 at 81,451,029 bp
  • A to G, chromosome 16 at 18,805,430 bp
  • T to A, chromosome 16 at 22,579,728 bp
  • G to A, chromosome 16 at 59,216,065 bp
  • T to G, chromosome 16 at 73,961,867 bp
  • G to A, chromosome 17 at 25,654,471 bp
  • A to G, chromosome 17 at 31,002,863 bp
  • T to A, chromosome 18 at 12,142,974 bp
  • T to A, chromosome 19 at 4,692,497 bp
  • C to A, chromosome 19 at 29,574,722 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3956 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040833-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.