Strain Name:
C57BL/6J-MtgxR4049Btlr/Mmmh
Stock Number:
041616-MU
Citation ID:
RRID:MMRRC_041616-MU
Other Names:
R4049 (G1), C57BL/6J-MtgxR4049Btlr
Major Collection:

Gene Information

Ncor1
Name: nuclear receptor co-repressor 1
Synonyms: A230020K14Rik, 5730405M06Rik, N-CoR, Rxrip13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20185
HGNC: HGNC:7672
Homologene: 38166
Rasgrp2
Name: RAS, guanyl releasing protein 2
Synonyms: Caldaggef1, CalDAG-GEFI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19395
HGNC: HGNC:9879
Homologene: 4250
Csf2
Name: colony stimulating factor 2 (granulocyte-macrophage)
Synonyms: MGI-IGM, Gm-CSf, Csfgm, GMCSF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12981
HGNC: HGNC:2434
Homologene: 600
Herc3
Name: hect domain and RLD 3
Synonyms: 5730409F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73998
HGNC: HGNC:4876
Homologene: 57095
Blm
Name: Bloom syndrome, RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12144
HGNC: HGNC:1058
Homologene: 47902
Mad1l1
Name: MAD1 mitotic arrest deficient 1-like 1
Synonyms: Mad1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17120
HGNC: HGNC:6762
Homologene: 74500
Rai14
Name: retinoic acid induced 14
Synonyms: 1700008J19Rik, 1700020L11Rik, Norpeg, Ankycorbin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75646
VEGA: 15
Homologene: 9199
Arhgef10
Name: Rho guanine nucleotide exchange factor (GEF) 10
Synonyms: 6430549H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234094
Homologene: 22827
Vps54
Name: VPS54 GARP complex subunit
Synonyms: wr, Vps54l, mSLP8, 5330404P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245944
Homologene: 5605
Ppp1r1a
Name: protein phosphatase 1, regulatory inhibitor subunit 1A
Synonyms: inhibitor-1, protein phosphatase inhibitor-1, I-1, 0610038N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 58200
VEGA: 15
HGNC: HGNC:9286
Homologene: 4905
Slc7a7
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
Synonyms: my+lat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 20540
Homologene: 88701
Brwd1
Name: bromodomain and WD repeat domain containing 1
Synonyms: D530019K20Rik, repro5, 5330419I02Rik, Wdr9, G1-403-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 93871
Homologene: 23130
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: PEPP2, Tg(AMH-cre)1Flor, 2810431N21Rik, Ayu21-9, Gt(Ayu21)9Imeg, AMH-Cre
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 109135
Homologene: 10377
Tcof1
Name: treacle ribosome biogenesis factor 1
Synonyms: treacle
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 21453
Homologene: 68049
Oprm1
Name: opioid receptor, mu 1
Synonyms: MOP-R, Oprm, mor, MOP receptor, muOR, MOR-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18390
HGNC: HGNC:8156
Homologene: 37368
Ctr9
Name: CTR9 homolog, Paf1/RNA polymerase II complex component
Synonyms: Tsp, Tsbp, Sh2bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22083
Homologene: 40668
Ube3b
Name: ubiquitin protein ligase E3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 117146
Homologene: 13775
Pphln1
Name: periphilin 1
Synonyms: CR, 1110063K05Rik, 1600022A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223828
VEGA: 15
Homologene: 9533
Zfp980
Name: zinc finger protein 980
Synonyms: Gm13242
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100041379
Homologene: 133076
Srsf4
Name: serine and arginine-rich splicing factor 4
Synonyms: 5730499P16Rik, MNCb-2616, SRp75, Sfrs4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 57317
Homologene: 25624
Tcf20
Name: transcription factor 20
Synonyms: stromelysin 1 PDGF responsive element binding protein, SPBP, 2810438H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21411
VEGA: 15
Homologene: 4131
Prokr2
Name: prokineticin receptor 2
Synonyms: PKR2, Gpcr73l1, B830005M06Rik, EG-VEGRF2, Gpr73l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 246313
Homologene: 16368
Snrpd2
Name: small nuclear ribonucleoprotein D2
Synonyms: 1810009A06Rik, SMD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 107686
Homologene: 3381
Zfp933
Name: zinc finger protein 933
Synonyms: 2810408P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242747
Homologene: 138474
Trim37
Name: tripartite motif-containing 37
Synonyms: 1110032A10Rik, MUL, 2810004E07Rik, TEF3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68729
HGNC: HGNC:7523
Homologene: 9084
Map4k3
Name: mitogen-activated protein kinase kinase kinase kinase 3
Synonyms: 9530052P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225028
VEGA: 17
HGNC: HGNC:6865
Homologene: 2683
Pcolce2
Name: procollagen C-endopeptidase enhancer 2
Synonyms: Pcpe2, 2400001O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76477
HGNC: HGNC:8739
Homologene: 8357
Thsd1
Name: thrombospondin, type I, domain 1
Synonyms: 4833423O18Rik, Tmtsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56229
Homologene: 10264
Map1lc3a
Name: microtubule-associated protein 1 light chain 3 alpha
Synonyms: 1010001H21Rik, 4922501H04Rik, LC3a, LC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66734
HGNC: HGNC:6838
Homologene: 12021
Cep57l1
Name: centrosomal protein 57-like 1
Synonyms: 2410017P07Rik, 4930484D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103268
Homologene: 12254
Ttll5
Name: tubulin tyrosine ligase-like family, member 5
Synonyms: STAMP, 2310009M18Rik, D630041K24Rik, 1700048H13Rik, 4930556H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320244
Homologene: 9013
Mov10l1
Name: Mov10 like RISC complex RNA helicase 1
Synonyms: CHAMP, Csm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 83456
HGNC: HGNC:7201
Homologene: 56835
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: C130041O22Rik, Zfh-4, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Gdf15
Name: growth differentiation factor 15
Synonyms: MIC-1, NAG-1, macrophage inhibiting cytokine-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23886
Homologene: 3576
Elf3
Name: E74-like factor 3
Synonyms: ESX, ESE-1, jen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13710
HGNC: HGNC:3318
Homologene: 3265
Egfem1
Name: EGF-like and EMI domain containing 1
Synonyms: 6130401L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75740
Homologene: 135950
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: tigmin, FPC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Eral1
Name: Era (G-protein)-like 1 (E. coli)
Synonyms: 2610524P08Rik, MERA-S, 9130407C09Rik, MERA-W
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57837
HGNC: HGNC:3424
Homologene: 4167
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Olfr1251
Name: olfactory receptor 1251
Synonyms: GA_x6K02T2Q125-51109312-51108356, MOR231-15P, MOR231-24_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259145
Homologene: 74065
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Il23r
Name: interleukin 23 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 209590
Homologene: 16930
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, OTTMUSG00000020804, Heatr7b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040766
Homologene: 85300
Wdr64
Name: WD repeat domain 64
Synonyms: 4930415O10Rik, 4930511H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75820
Homologene: 51634
Arhgef10l
Name: Rho guanine nucleotide exchange factor (GEF) 10-like
Synonyms: 2810441C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72754
Homologene: 10017
Abcb5
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Dennd3
Name: DENN/MADD domain containing 3
Synonyms: E030003N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105841
Homologene: 28254
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: C230094A16Rik, 2900083P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237711
Homologene: 104282
Col16a1
Name: collagen, type XVI, alpha 1
Synonyms: [a]1 (XVI) collagen, 2700007F12Rik, A530052M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 107581
HGNC: HGNC:2193
Homologene: 1397
Tmc6
Name: transmembrane channel-like gene family 6
Synonyms: EVER1, D11Ertd204e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217353
Homologene: 5258
Enthd1
Name: ENTH domain containing 1
Synonyms: LOC383075
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 383075
VEGA: 15
Homologene: 45131
Ccdc63
Name: coiled-coil domain containing 63
Synonyms: 4921511C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330188
Homologene: 45136
Olfr1212
Name: olfactory receptor 1212
Synonyms: MOR233-17, MOR233-20, GA_x6K02T2Q125-50437014-50437949
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258241
Homologene: 66154
Pfpl
Name: pore forming protein-like
Synonyms: Epcs50, Epcs5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56093
VEGA: 19
Homologene: 130704
Ggps1
Name: geranylgeranyl diphosphate synthase 1
Synonyms: 9530089B04Rik, 1810026C22Rik, GGPP synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14593
VEGA: 13
HGNC: HGNC:4249
Homologene: 31267
Olfr653
Name: olfactory receptor 653
Synonyms: GA_x6K02T2PBJ9-7206970-7207923, MOR33-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57250
Homologene: 115518
Ccn5
Name: cellular communication network factor 5
Synonyms: Crgr4, Wisp2, CCN5, rCop1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22403
Homologene: 2882
Slc23a2
Name: solute carrier family 23 (nucleobase transporters), member 2
Synonyms: SVCT2, YSPL3, Slc23a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54338
Homologene: 68440
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625109
Homologene: 129606
Spire1
Name: spire type actin nucleation factor 1
Synonyms: Spir-1, 6030430B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68166
VEGA: 18
Homologene: 35507
Timm44
Name: translocase of inner mitochondrial membrane 44
Synonyms: D8Ertd118e, Mimt44, 0710005E20Rik, Tim44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21856
Homologene: 4631
Cyp3a41a
Name: cytochrome P450, family 3, subfamily a, polypeptide 41A
Synonyms: Cyp3a41, steroid inducible
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 53973
HGNC: HGNC:2638
Homologene: 133568
Nfe2
Name: nuclear factor, erythroid derived 2
Synonyms: p45NFE2, NF-E2, p45nf-e2, p45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18022
HGNC: HGNC:7780
Homologene: 4491
Clstn2
Name: calsyntenin 2
Synonyms: CSTN2, 2900042C18Rik, Cst-2, CS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 64085
Homologene: 49698
Zfp703
Name: zinc finger protein 703
Synonyms: Csmn1, 1110032O19Rik, End2, Zeppo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 353310
Homologene: 81391
Gm8074
Name: predicted gene 8074
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Olfr1177-ps
Name: olfactory receptor 1177, pseudogene
Synonyms: GA_x6K02T2Q125-49829472-49828534, MOR174-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545443
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 20,553,608 bp
  • A to G, chromosome 1 at 88,258,664 bp
  • T to C, chromosome 1 at 135,254,277 bp
  • T to G, chromosome 1 at 175,805,856 bp
  • T to C, chromosome 2 at 88,343,800 bp
  • A to G, chromosome 2 at 88,959,273 bp
  • T to C, chromosome 2 at 89,667,662 bp
  • C to T, chromosome 2 at 132,060,683 bp
  • T to C, chromosome 2 at 132,381,494 bp
  • G to T, chromosome 2 at 155,277,542 bp
  • A to G, chromosome 2 at 163,828,984 bp
  • C to T, chromosome 3 at 5,398,859 bp
  • A to C, chromosome 3 at 29,686,731 bp
  • C to T, chromosome 4 at 130,068,752 bp
  • T to C, chromosome 4 at 131,900,543 bp
  • T to A, chromosome 4 at 140,515,451 bp
  • A to G, chromosome 4 at 145,702,600 bp
  • T to C, chromosome 4 at 147,826,512 bp
  • T to A, chromosome 5 at 62,827,165 bp
  • T to C, chromosome 5 at 114,412,870 bp
  • T to A, chromosome 5 at 122,122,750 bp
  • A to G, chromosome 5 at 140,132,816 bp
  • A to G, chromosome 5 at 145,713,540 bp
  • A to G, chromosome 6 at 58,876,837 bp
  • A to T, chromosome 6 at 67,466,433 bp
  • T to C, chromosome 6 at 140,583,871 bp
  • T to A, chromosome 7 at 19,151,307 bp
  • T to A, chromosome 7 at 80,502,862 bp
  • T to C, chromosome 7 at 104,580,368 bp
  • C to T, chromosome 7 at 111,055,543 bp
  • A to G, chromosome 8 at 4,260,561 bp
  • A to G, chromosome 8 at 14,979,998 bp
  • T to A, chromosome 8 at 22,243,164 bp
  • A to G, chromosome 8 at 26,979,085 bp
  • A to T, chromosome 8 at 70,629,955 bp
  • G to A, chromosome 9 at 78,322,336 bp
  • A to T, chromosome 9 at 95,638,755 bp
  • T to G, chromosome 9 at 97,457,560 bp
  • G to A, chromosome 10 at 6,829,087 bp
  • G to T, chromosome 10 at 41,729,360 bp
  • A to T, chromosome 10 at 130,447,097 bp
  • C to A, chromosome 11 at 21,300,183 bp
  • C to T, chromosome 11 at 29,838,577 bp
  • A to G, chromosome 11 at 54,249,333 bp
  • G to T, chromosome 11 at 62,329,668 bp
  • A to G, chromosome 11 at 78,075,602 bp
  • T to A, chromosome 11 at 87,140,603 bp
  • G to A, chromosome 11 at 117,778,261 bp
  • A to C, chromosome 11 at 119,482,448 bp
  • T to C, chromosome 12 at 86,012,799 bp
  • T to A, chromosome 12 at 118,868,669 bp
  • T to C, chromosome 13 at 14,053,699 bp
  • T to C, chromosome 14 at 54,373,091 bp
  • T to C, chromosome 15 at 10,592,212 bp
  • G to A, chromosome 15 at 44,498,557 bp
  • T to C, chromosome 15 at 73,522,215 bp
  • T to C, chromosome 15 at 80,560,039 bp
  • A to G, chromosome 15 at 82,853,429 bp
  • T to A, chromosome 15 at 88,995,032 bp
  • C to A, chromosome 15 at 93,465,106 bp
  • C to T, chromosome 15 at 103,250,937 bp
  • A to G, chromosome 15 at 103,532,454 bp
  • A to T, chromosome 16 at 96,013,885 bp
  • A to G, chromosome 17 at 80,605,965 bp
  • C to A, chromosome 18 at 60,832,903 bp
  • G to T, chromosome 18 at 67,529,031 bp
  • T to C, chromosome 19 at 6,404,727 bp
  • T to A, chromosome 19 at 12,429,689 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4049 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041616-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.