Strain Name:
C57BL/6J-MtgxR4093Btlr/Mmmh
Stock Number:
041627-MU
Citation ID:
RRID:MMRRC_041627-MU
Other Names:
R4093 (G1), C57BL/6J-MtgxR4093Btlr
Major Collection:

Gene Information

Htr2a
Name: 5-hydroxytryptamine (serotonin) receptor 2A
Synonyms: 5-HT2A receptor, Htr-2, Htr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 15558
VEGA: 14
HGNC: HGNC:5293
Homologene: 68073
Zdbf2
Name: zinc finger, DBF-type containing 2
Synonyms: 9330107J05Rik, 4930431J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 73884
Homologene: 52868
Wfs1
Name: wolframin ER transmembrane glycoprotein
Synonyms: wolframin, Wolfram syndrome 1 homolog (human)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22393
Homologene: 4380
Ltbp4
Name: latent transforming growth factor beta binding protein 4
Synonyms: 2310046A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 108075
HGNC: HGNC:6717
Homologene: 2645
Sfswap
Name: splicing factor SWAP
Synonyms: Sfrs8, 6330437E22Rik, 1190005N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231769
Homologene: 134548
Proser1
Name: proline and serine rich 1
Synonyms: 2810046L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 212127
Homologene: 13463
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: mei2-5, G1-448-15, 5730481H23Rik, AKAP450, repro12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Zfp64
Name: zinc finger protein 64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22722
Homologene: 7604
Med27
Name: mediator complex subunit 27
Synonyms: Crsp8, 1500015J03Rik, 2310042P07Rik, D2Ertd434e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68975
HGNC: HGNC:2377
Homologene: 3152
Cip2a
Name: cell proliferation regulating inhibitor of protein phosphatase 2A
Synonyms: C330027C09Rik, Cip2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224171
Homologene: 10842
Pygo2
Name: pygopus 2
Synonyms: 1190004M21Rik, mpygo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68911
Homologene: 44519
Myt1
Name: myelin transcription factor 1
Synonyms: NZF-2a, Nztf2, Nzf2, NZF-2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17932
HGNC: HGNC:7622
Homologene: 3332
Lrig1
Name: leucine-rich repeats and immunoglobulin-like domains 1
Synonyms: Img, LIG-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16206
Homologene: 7380
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 2810040A01Rik, 5630401D06Rik, 2810013C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: Doc4, ELM2, l7Rn3, Odz4, Ten-m4, l(7)-3Rn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23966
Homologene: 8034
Kansl3
Name: KAT8 regulatory NSL complex subunit 3
Synonyms: 4632411B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226976
Homologene: 9949
Recql5
Name: RecQ protein-like 5
Synonyms: Recql5b, Recq5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 170472
HGNC: HGNC:9950
Homologene: 31232
Alas1
Name: aminolevulinic acid synthase 1
Synonyms: succinyl-CoA: glycine C-succinyl transferase, 5-aminolevulinate synthase, ALAS-N, Alas-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11655
HGNC: HGNC:396
Homologene: 55478
Ppp1r12c
Name: protein phosphatase 1, regulatory subunit 12C
Synonyms: Mbs85, 2410197A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232807
Homologene: 75071
Trpc1
Name: transient receptor potential cation channel, subfamily C, member 1
Synonyms: Mtrp1, Trrp1, Trp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22063
Homologene: 2478
Nlrc4
Name: NLR family, CARD domain containing 4
Synonyms: 9530011P19Rik, Card12, Ipaf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268973
VEGA: 17
Homologene: 10924
Cfap70
Name: cilia and flagella associated protein 70
Synonyms: 5330402L21Rik, Ttc18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 76670
Homologene: 17048
Npy4r
Name: neuropeptide Y receptor Y4
Synonyms: Y4, NYYR-D, Ppyr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19065
VEGA: 14
HGNC: HGNC:9329
Homologene: 38119
Kcnab1
Name: potassium voltage-gated channel, shaker-related subfamily, beta member 1
Synonyms: Kvbeta1.1, Akr8a8, mKv(beta)1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16497
HGNC: HGNC:6228
Homologene: 56491
Zfp943
Name: zinc finger prtoein 943
Synonyms: 4930432O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74670
Homologene: 134342
Hc
Name: hemolytic complement
Synonyms: C5, C5a, Hfib2, He
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Atp2c2
Name: ATPase, Ca++ transporting, type 2C, member 2
Synonyms: 1810010G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 69047
Homologene: 73463
Slc4a5
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5
Synonyms: C330016K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232156
Homologene: 31125
Serpina12
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
Synonyms: vaspin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68054
Homologene: 23588
Vmn2r110
Name: vomeronasal 2, receptor 110
Synonyms: EG224582
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224582
Homologene: 129678
Tbx3
Name: T-box 3
Synonyms: D5Ertd189e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 21386
Homologene: 4371
Taok2
Name: TAO kinase 2
Synonyms: TAO2, TAO1, 1110033K02Rik, PSK1, MAP3K17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381921
Homologene: 74531
Cadm2
Name: cell adhesion molecule 2
Synonyms: SynCAM2, Igsf4d, A830029E02Rik, Necl3, 2900078E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239857
Homologene: 17705
Trim60
Name: tripartite motif-containing 60
Synonyms: Rnf33, 2czf45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234329
Homologene: 51876
Kcnt1
Name: potassium channel, subfamily T, member 1
Synonyms: slo2, C030030G16Rik, Slack
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227632
Homologene: 11055
Chrnd
Name: cholinergic receptor, nicotinic, delta polypeptide
Synonyms: Acrd, Achr-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11447
HGNC: HGNC:1965
Homologene: 37340
Unc5d
Name: unc-5 netrin receptor D
Synonyms: D930029E11Rik, Unc5h4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 210801
Homologene: 15450
Hoxb3
Name: homeobox B3
Synonyms: Hox-2.7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15410
HGNC: HGNC:5114
Homologene: 1617
Olfr904
Name: olfactory receptor 904
Synonyms: MOR167-3, GA_x6K02T2PVTD-32156773-32157705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258797
VEGA: 9
Homologene: 133629
Traf3ip3
Name: TRAF3 interacting protein 3
Synonyms: 6030423D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 215243
Homologene: 11885
Gsdma2
Name: gasdermin A2
Synonyms: 2200001G21Rik, 2210411P14Rik, Gsdml2, 2210009F20Rik, 2210006M16Rik, Gsdm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76758
Mfsd2b
Name: major facilitator superfamily domain containing 2B
Synonyms: Gm1964
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 432628
Homologene: 47753
Vstm2a
Name: V-set and transmembrane domain containing 2A
Synonyms: Vstm2, 9330184N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 211739
Homologene: 17123
Vmn1r185
Name: vomeronasal 1 receptor 185
Synonyms: V1re12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171265
Homologene: 74353
Angpt1
Name: angiopoietin 1
Synonyms: Ang-1, Angiopoietin-1, 1110046O21Rik, ang1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 11600
VEGA: 15
HGNC: HGNC:484
Homologene: 37447
Spag6l
Name: sperm associated antigen 6-like
Synonyms: PF16, Spag6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 50525
Homologene: 8252
Lrrc31
Name: leucine rich repeat containing 31
Synonyms: E230002P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 320352
Lcn2
Name: lipocalin 2
Synonyms: NRL, neu-related lipocalin, 24p3, NGAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16819
HGNC: HGNC:6526
Homologene: 4064
Olfr672
Name: olfactory receptor 672
Synonyms: MOR32-4, GA_x6K02T2PBJ9-7625746-7624808
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258755
Homologene: 138317
Lrp8
Name: low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Synonyms: apoER2, 4932703M08Rik, Lr8b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16975
HGNC: HGNC:6700
Homologene: 31250
Vmn1r62
Name: vomeronasal 1 receptor 62
Synonyms: V1rd2, V3R2, V1rd8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 81016
Homologene: 41799
Tubgcp4
Name: tubulin, gamma complex associated protein 4
Synonyms: D2Ertd435e, 4932441P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 51885
Homologene: 8690
Slc22a2
Name: solute carrier family 22 (organic cation transporter), member 2
Synonyms: Orct2, Oct2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20518
VEGA: 17
Homologene: 68293
Vmn2r71
Name: vomeronasal 2, receptor 71
Synonyms: EG233445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233445
Homologene: 115466
Srl
Name: sarcalumenin
Synonyms: sar, 9830004M20Rik, sarcalumenin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 106393
Homologene: 45500
Klk15
Name: kallikrein related-peptidase 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 317652
Homologene: 77571
Olfr282
Name: olfactory receptor 282
Synonyms: GA_x6K02T2NBG7-5293798-5292872, MOR160-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 258449
Homologene: 133621
Zfp61
Name: zinc finger protein 61
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22719
Homologene: 74923
Smpd2
Name: sphingomyelin phosphodiesterase 2, neutral
Synonyms: nSMase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20598
Homologene: 31129
Gm20388
Name: predicted gene 20388
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
Olfr224
Name: olfactory receptor 224
Synonyms: Olfr327-ps1, MOR275-3, GA_x6K02T2NKPP-858022-858862, GA_x6K02T00261-652-347, MOR275-10_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258198
Homologene: 133015
Tagap
Name: T cell activation Rho GTPase activating protein
Synonyms: TRD, Tcd1a, tcs1, tcs-1, Tcd-1, Tcd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72536
Homologene: 44943
Cym
Name: chymosin
Synonyms: Gm131, LOC229697
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229697
Homologene: 129841
Vmn1r57
Name: vomeronasal 1 receptor 57
Synonyms: Gm7519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 665150
Homologene: 41799
Psme2
Name: proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Synonyms: PA28b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19188
HGNC: HGNC:9569
Homologene: 86889
Rab11b
Name: RAB11B, member RAS oncogene family
Synonyms: A730055L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19326
HGNC: HGNC:9761
Homologene: 68691
Vmn2r-ps36
Name: vomeronasal 2, receptor, pseudogene 36
Synonyms: EG665442
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 665442
RP23-455B5.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
Fam115c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
Vmn2r48
Name: vomeronasal 2, receptor 48
Synonyms: EG625580
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 625580
Homologene: 113703
D030068K23Rik
Name: RIKEN cDNA D030068K23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 628686
Ighv1-19
Name: immunoglobulin heavy variable V1-19
Synonyms: Gm16855
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 382692
Gm3650
Name: predicted gene 3650
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 100042074
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 36,344,954 bp
  • T to C, chromosome 1 at 63,309,781 bp
  • C to T, chromosome 1 at 87,191,007 bp
  • T to C, chromosome 1 at 193,181,364 bp
  • A to T, chromosome 2 at 25,877,915 bp
  • G to A, chromosome 2 at 29,377,908 bp
  • A to T, chromosome 2 at 32,387,716 bp
  • A to T, chromosome 2 at 34,983,807 bp
  • T to A, chromosome 2 at 121,195,477 bp
  • T to C, chromosome 2 at 168,925,935 bp
  • A to T, chromosome 2 at 181,811,398 bp
  • C to A, chromosome 3 at 30,695,522 bp
  • T to C, chromosome 3 at 53,479,712 bp
  • T to C, chromosome 3 at 65,299,614 bp
  • C to A, chromosome 3 at 89,433,264 bp
  • A to T, chromosome 3 at 93,727,237 bp
  • A to G, chromosome 3 at 107,214,266 bp
  • T to A, chromosome 4 at 107,843,271 bp
  • A to G, chromosome 5 at 4,043,996 bp
  • T to C, chromosome 5 at 36,967,465 bp
  • T to A, chromosome 5 at 119,680,748 bp
  • A to G, chromosome 5 at 129,560,741 bp
  • A to G, chromosome 6 at 42,642,838 bp
  • T to C, chromosome 6 at 83,289,164 bp
  • T to C, chromosome 6 at 94,613,578 bp
  • T to C, chromosome 7 at 4,483,367 bp
  • G to T, chromosome 7 at 5,220,857 bp
  • T to A, chromosome 7 at 5,675,944 bp
  • A to G, chromosome 7 at 7,430,337 bp
  • C to A, chromosome 7 at 9,942,258 bp
  • T to A, chromosome 7 at 9,942,259 bp
  • A to G, chromosome 7 at 24,291,275 bp
  • A to T, chromosome 7 at 26,611,783 bp
  • A to G, chromosome 7 at 27,325,216 bp
  • A to T, chromosome 7 at 43,938,780 bp
  • C to T, chromosome 7 at 73,501,016 bp
  • T to C, chromosome 7 at 85,621,234 bp
  • A to T, chromosome 7 at 96,895,772 bp
  • C to T, chromosome 7 at 104,996,635 bp
  • A to G, chromosome 7 at 126,866,871 bp
  • T to C, chromosome 8 at 28,844,837 bp
  • A to T, chromosome 8 at 65,001,378 bp
  • A to G, chromosome 8 at 109,251,459 bp
  • G to A, chromosome 8 at 119,749,871 bp
  • A to C, chromosome 8 at 122,501,160 bp
  • T to A, chromosome 9 at 38,464,083 bp
  • T to C, chromosome 9 at 95,706,865 bp
  • G to T, chromosome 9 at 106,241,801 bp
  • T to C, chromosome 10 at 41,486,937 bp
  • A to G, chromosome 11 at 16,259,884 bp
  • A to T, chromosome 11 at 58,566,829 bp
  • C to A, chromosome 11 at 96,346,100 bp
  • T to A, chromosome 11 at 98,650,851 bp
  • A to G, chromosome 11 at 115,904,888 bp
  • A to G, chromosome 12 at 4,865,241 bp
  • A to G, chromosome 12 at 104,037,924 bp
  • G to A, chromosome 12 at 114,708,730 bp
  • A to T, chromosome 14 at 20,409,113 bp
  • T to C, chromosome 14 at 34,147,141 bp
  • A to T, chromosome 14 at 55,588,277 bp
  • G to A, chromosome 14 at 74,706,349 bp
  • T to C, chromosome 15 at 42,523,545 bp
  • T to C, chromosome 15 at 98,437,682 bp
  • A to G, chromosome 16 at 4,497,452 bp
  • A to C, chromosome 16 at 16,829,024 bp
  • T to C, chromosome 16 at 49,000,976 bp
  • A to G, chromosome 16 at 66,784,788 bp
  • A to T, chromosome 17 at 7,929,423 bp
  • C to T, chromosome 17 at 12,612,394 bp
  • T to C, chromosome 17 at 20,583,380 bp
  • T to A, chromosome 17 at 21,992,982 bp
  • T to C, chromosome 17 at 33,749,789 bp
  • T to C, chromosome 17 at 74,445,958 bp
  • A to T, chromosome 18 at 43,475,126 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4093 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041627-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.