Strain Name:
C57BL/6J-MtgxR4608Btlr/Mmmh
Stock Number:
041819-MU
Citation ID:
RRID:MMRRC_041819-MU
Other Names:
R4608 (G1), C57BL/6J-MtgxR4608Btlr
Major Collection:

Gene Information

Col2a1
Name: collagen, type II, alpha 1
Synonyms: Col2, Col2a, Lpk, Col2a-1, M100856, M100413, Rgsc413, Del1, Rgsc856
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12824
HGNC: HGNC:2200
Homologene: 55607
Slc12a5
Name: solute carrier family 12, member 5
Synonyms: KCC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57138
Homologene: 10665
Tlr9
Name: toll-like receptor 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 81897
Homologene: 68126
Ints6
Name: integrator complex subunit 6
Synonyms: Notch2l, 2900075H24Rik, Ddx26, DICE1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18130
VEGA: 14
Homologene: 8121
Fastk
Name: Fas-activated serine/threonine kinase
Synonyms: 0610011K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66587
Homologene: 4884
Uba2
Name: ubiquitin-like modifier activating enzyme 2
Synonyms: Uble1b, SAE2, Arx, anthracycline-associated resistance, UBA2, Sumo-1 activating enzyme subunit 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 50995
Homologene: 4018
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: G1-419-52, 4930523M17Rik, 1500002J22Rik, eIF4GII, repro8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Ints1
Name: integrator complex subunit 1
Synonyms: 1110015K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68510
Homologene: 53111
Lrch4
Name: leucine-rich repeats and calponin homology (CH) domain containing 4
Synonyms: 2810008P14Rik, LRN, 2900069C24Rik, SAP25, LRRN4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231798
HGNC: HGNC:6691
Homologene: 20532
Ints9
Name: integrator complex subunit 9
Synonyms: D14Ertd231e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 210925
VEGA: 14
Homologene: 10096
Wdr7
Name: WD repeat domain 7
Synonyms: TGF-beta resistance associated gene, TRAG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 104082
VEGA: 18
Homologene: 11408
Fancc
Name: Fanconi anemia, complementation group C
Synonyms: Facc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14088
HGNC: HGNC:3584
Homologene: 109
Gls
Name: glutaminase
Synonyms: B230365M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14660
HGNC: HGNC:4331
Homologene: 22726
Adrm1
Name: adhesion regulating molecule 1
Synonyms: ARM-1, 2510006J17Rik, Rpn13, 1110063P18Rik, Gp110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56436
Homologene: 10513
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Dcdc2a
Name: doublecortin domain containing 2a
Synonyms: RU2, Dcdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 195208
Homologene: 9483
Lef1
Name: lymphoid enhancer binding factor 1
Synonyms: Lef-1, lymphoid enhancer factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 16842
HGNC: HGNC:6551
Homologene: 7813
Nrip1
Name: nuclear receptor interacting protein 1
Synonyms: 6030458L20Rik, 8430438I05Rik, RIP140
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268903
HGNC: HGNC:8001
Homologene: 2606
Uty
Name: ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
Synonyms: Hydb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22290
Leng8
Name: leukocyte receptor cluster (LRC) member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232798
Homologene: 13612
Hhip
Name: Hedgehog-interacting protein
Synonyms: Hip, Hip1, Hhip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 15245
Homologene: 32469
Pms1
Name: PMS1 homolog 1, mismatch repair system component
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227099
HGNC: HGNC:9121
Homologene: 449
Nxf1
Name: nuclear RNA export factor 1
Synonyms: TAP, Mvb1, Tip associated protein, Mex67
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 53319
HGNC: HGNC:8071
Homologene: 38176
Fmnl2
Name: formin-like 2
Synonyms: 5430425K04Rik, man
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71409
Homologene: 70871
Stimate
Name: STIM activating enhancer
Synonyms: Tmem110, 1810038N08Rik, 2310014H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 69179
Homologene: 7082
Memo1
Name: mediator of cell motility 1
Synonyms: D930048L02Rik, 0610016J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76890
VEGA: 17
Homologene: 6272
Ythdc1
Name: YTH domain containing 1
Synonyms: A730098D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231386
Homologene: 15796
Aqp4
Name: aquaporin 4
Synonyms: aquaporin-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11829
VEGA: 18
HGNC: HGNC:637
Homologene: 37507
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
F5
Name: coagulation factor V
Synonyms: Cf5, Cf-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Gckr
Name: glucokinase regulatory protein
Synonyms: GKRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231103
HGNC: HGNC:4196
Homologene: 1139
Ints10
Name: integrator complex subunit 10
Synonyms: 4921521J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 70885
Homologene: 10029
Zfand4
Name: zinc finger, AN1-type domain 4
Synonyms: 2810002D23Rik, Anubl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67492
VEGA: 6
Homologene: 18373
Kif1a
Name: kinesin family member 1A
Synonyms: C630002N23Rik, Kns1, ATSV, LOC381283, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Zfp804b
Name: zinc finger protein 804B
Synonyms: LOC207618
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 207618
Homologene: 52304
Acss3
Name: acyl-CoA synthetase short-chain family member 3
Synonyms: 8430416H19Rik, LOC380660
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 380660
Homologene: 11587
Adamts7
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
Synonyms: ADAM-TS7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108153
HGNC: HGNC:223
Homologene: 22803
Xab2
Name: XPA binding protein 2
Synonyms: 0610041O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67439
Homologene: 5738
Ggt6
Name: gamma-glutamyltransferase 6
Synonyms: 9030405D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71522
Homologene: 51918
Slc1a4
Name: solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Synonyms: ASCT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 55963
Homologene: 20655
Krtap4-8
Name: keratin associated protein 4-8
Synonyms: OTTMUSG00000002541
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 665992
Nod1
Name: nucleotide-binding oligomerization domain containing 1
Synonyms: F830007N14Rik, Nlrc1, Card4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 107607
Homologene: 4440
Bbs10
Name: Bardet-Biedl syndrome 10 (human)
Synonyms: 1300007O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71769
VEGA: 10
Homologene: 49781
Adam10
Name: a disintegrin and metallopeptidase domain 10
Synonyms: kuzbanian, kuz, 1700031C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11487
HGNC: HGNC:188
Homologene: 865
Fes
Name: feline sarcoma oncogene
Synonyms: c-fes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14159
HGNC: HGNC:3657
Homologene: 37563
Adamts18
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
Synonyms: E130314N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 208936
Homologene: 65241
Rxfp1
Name: relaxin/insulin-like family peptide receptor 1
Synonyms: Lgr7, LOC381489
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 381489
Homologene: 11007
Fam187b
Name: family with sequence similarity 187, member B
Synonyms: Tmem162, 1700020B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76415
Homologene: 138431
Aqp1
Name: aquaporin 1
Synonyms: CHIP28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11826
HGNC: HGNC:633
Homologene: 68051
B130006D01Rik
Name: RIKEN cDNA B130006D01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 320616
VEGA: 11
Kif21b
Name: kinesin family member 21B
Synonyms: 2610511N21Rik, N-5 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16565
Homologene: 56868
P2ry6
Name: pyrimidinergic receptor P2Y, G-protein coupled, 6
Synonyms: P2Y6, 2010204J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233571
HGNC: HGNC:8543
Homologene: 14289
Klk13
Name: kallikrein related-peptidase 13
Synonyms: mGk-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 626834
HGNC: HGNC:6361
Homologene: 56714
Nostrin
Name: nitric oxide synthase trafficker
Synonyms: mDaIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329416
Homologene: 43142
Itih4
Name: inter alpha-trypsin inhibitor, heavy chain 4
Synonyms: Itih-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16427
HGNC: HGNC:6169
Homologene: 1670
Olfr31
Name: olfactory receptor 31
Synonyms: MTPCR53, GA_x6K02T2PLTE-6714644-6715597, MOR274-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18330
HGNC: HGNC:8277
Homologene: 74028
Pgghg
Name: protein glucosylgalactosylhydroxylysine glucosidase
Synonyms: 5730511L01Rik, Athl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212974
Homologene: 16023
Crocc2
Name: ciliary rootlet coiled-coil, rootletin family member 2
Synonyms: LOC381284, E030010N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381284
Homologene: 141152
Olfr1219
Name: olfactory receptor 1219
Synonyms: MOR233-6, GA_x6K02T2Q125-50555603-50554668
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258901
Homologene: 27292
Gsg1l
Name: GSG1-like
Synonyms: C230098I05Rik, G630023A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269994
Homologene: 78152
Qars
Name: glutaminyl-tRNA synthetase
Synonyms: 1200016L19Rik, 1110018N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 97541
HGNC: HGNC:9751
Homologene: 133975
Olfr538
Name: olfactory receptor 538
Synonyms: Olfr1523-ps1, GA_x6K02T2PBJ9-42723314-42724246, MOR253-13P, MOR253-12P, MOR253-13P, MOR253-12P, Olfr1553-ps1, MOR253-10P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258201
Homologene: 110491
Gm6588
Name: predicted gene 6588
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 625464
Homologene: 116059
Olfr365
Name: olfactory receptor 365
Synonyms: GA_x6K02T2NLDC-33885305-33886243, MOR138-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258656
Homologene: 74156
Tmem74
Name: transmembrane protein 74
Synonyms: B230382K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239408
VEGA: 15
Homologene: 17684
9930022D16Rik
Name: RIKEN cDNA 9930022D16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Olfr303
Name: olfactory receptor 303
Synonyms: MOR104-2, GA_x6K02T2NHDJ-9712819-9713778
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258612
Homologene: 105157
Ccnl1
Name: cyclin L1
Synonyms: 2610030E23Rik, ania-6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56706
Homologene: 10541
Fpgt
Name: fucose-1-phosphate guanylyltransferase
Synonyms: 1700016E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75540
HGNC: HGNC:3825
Homologene: 2847
Osgep
Name: O-sialoglycoprotein endopeptidase
Synonyms: 1500019L24Rik, GCPL-1, PRSMG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66246
Homologene: 6395
Pcdha7
Name: protocadherin alpha 7
Synonyms: Crnr4, Cnr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12939
HGNC: HGNC:8673
Homologene: 117962
Olfr753-ps1
Name: olfactory receptor 753, pseudogene 1
Synonyms: MOR256-38, GA_x6K02T2PSCP-1611898-1610960
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258052
Gm26657
Name: predicted gene, 26657
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Zfp367
Name: zinc finger protein 367
Synonyms: ZFF29b, ZFF29a, 8030486J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238673
Homologene: 17802
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 52,232,768 bp
  • T to A, chromosome 1 at 53,194,938 bp
  • C to A, chromosome 1 at 93,024,646 bp
  • G to A, chromosome 1 at 93,168,794 bp
  • C to T, chromosome 1 at 136,148,186 bp
  • C to T, chromosome 1 at 164,209,029 bp
  • T to A, chromosome 2 at 37,202,082 bp
  • T to A, chromosome 2 at 53,103,716 bp
  • G to A, chromosome 2 at 69,183,899 bp
  • G to T, chromosome 2 at 89,074,312 bp
  • A to C, chromosome 2 at 125,306,500 bp
  • A to T, chromosome 2 at 164,973,765 bp
  • A to G, chromosome 2 at 180,174,855 bp
  • C to T, chromosome 3 at 65,946,710 bp
  • T to C, chromosome 3 at 79,686,889 bp
  • T to C, chromosome 3 at 131,184,733 bp
  • G to A, chromosome 3 at 155,086,696 bp
  • C to A, chromosome 4 at 56,741,114 bp
  • C to T, chromosome 4 at 104,731,751 bp
  • G to T, chromosome 4 at 138,126,458 bp
  • C to T, chromosome 5 at 6,772,584 bp
  • G to T, chromosome 5 at 24,443,119 bp
  • A to G, chromosome 5 at 31,307,797 bp
  • T to C, chromosome 5 at 86,822,808 bp
  • A to G, chromosome 5 at 112,449,898 bp
  • T to A, chromosome 5 at 137,639,146 bp
  • C to T, chromosome 5 at 139,759,844 bp
  • C to A, chromosome 6 at 54,943,756 bp
  • T to C, chromosome 6 at 55,336,639 bp
  • T to A, chromosome 6 at 116,328,234 bp
  • T to A, chromosome 7 at 4,144,797 bp
  • T to A, chromosome 7 at 30,977,745 bp
  • T to C, chromosome 7 at 34,154,596 bp
  • C to A, chromosome 7 at 43,713,860 bp
  • G to A, chromosome 7 at 80,387,211 bp
  • A to T, chromosome 7 at 86,394,510 bp
  • A to G, chromosome 7 at 100,938,304 bp
  • T to A, chromosome 7 at 125,958,549 bp
  • A to G, chromosome 7 at 140,574,641 bp
  • T to C, chromosome 7 at 140,943,433 bp
  • A to G, chromosome 8 at 3,618,105 bp
  • G to A, chromosome 8 at 68,810,619 bp
  • C to T, chromosome 8 at 79,997,563 bp
  • A to T, chromosome 8 at 113,737,613 bp
  • T to C, chromosome 9 at 70,743,891 bp
  • T to G, chromosome 9 at 90,174,540 bp
  • T to A, chromosome 9 at 106,224,974 bp
  • T to A, chromosome 9 at 108,509,426 bp
  • T to A, chromosome 10 at 106,967,029 bp
  • T to G, chromosome 10 at 111,300,820 bp
  • A to G, chromosome 10 at 111,301,134 bp
  • G to T, chromosome 11 at 20,304,348 bp
  • T to C, chromosome 11 at 72,437,943 bp
  • A to T, chromosome 11 at 95,726,240 bp
  • C to T, chromosome 11 at 99,780,495 bp
  • A to G, chromosome 11 at 109,418,029 bp
  • T to A, chromosome 13 at 25,061,240 bp
  • C to A, chromosome 13 at 63,331,823 bp
  • C to T, chromosome 13 at 64,135,424 bp
  • A to G, chromosome 14 at 14,328,887 bp
  • C to A, chromosome 14 at 30,872,533 bp
  • G to A, chromosome 14 at 30,901,669 bp
  • T to C, chromosome 14 at 50,917,921 bp
  • T to G, chromosome 14 at 62,703,229 bp
  • T to A, chromosome 14 at 65,032,280 bp
  • G to T, chromosome 15 at 43,867,158 bp
  • A to G, chromosome 15 at 98,000,404 bp
  • T to C, chromosome 16 at 76,293,032 bp
  • A to T, chromosome 17 at 37,170,282 bp
  • G to A, chromosome 17 at 74,258,461 bp
  • T to C, chromosome 18 at 15,398,126 bp
  • A to T, chromosome 18 at 36,975,817 bp
  • C to T, chromosome 18 at 63,777,580 bp
  • A to G, chromosome 19 at 8,762,763 bp
  • C to T, chromosome Y at 1,131,134 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4608 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041819-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.