Strain Name:
C57BL/6J-MtgxR4977Btlr/Mmmh
Stock Number:
042572-MU
Citation ID:
RRID:MMRRC_042572-MU
Other Names:
R4977 (G1), C57BL/6J-MtgxR4977Btlr
Major Collection:

Strain Information

Hyal1
Name: hyaluronoglucosaminidase 1
Synonyms: Hyal-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15586
HGNC: HGNC:5320
Homologene: 5277
Runx1
Name: runt related transcription factor 1
Synonyms: Cbfa2, Pebp2a2, runt domain, alpha subunit 2, AML1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12394
Homologene: 1331
Plg
Name: plasminogen
Synonyms: Pg
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18815
VEGA: 17
HGNC: HGNC:9071
Homologene: 55452
Emx2
Name: empty spiracles homeobox 2
Synonyms: Pdo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13797
HGNC: HGNC:3341
Homologene: 3023
Lrrn1
Name: leucine rich repeat protein 1, neuronal
Synonyms: NLRR-1, 2810047E21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16979
Homologene: 32036
Il21
Name: interleukin 21
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 60505
HGNC: HGNC:6005
Homologene: 11032
Pex7
Name: peroxisomal biogenesis factor 7
Synonyms: peroxisome biogenesis factor 7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18634
HGNC: HGNC:8860
Homologene: 242
Plxnd1
Name: plexin D1
Synonyms: b2b1863Clo, b2b553Clo, 6230425C21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Cdyl2
Name: chromodomain protein, Y chromosome-like 2
Synonyms: 4930453I21Rik, 1700029M19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75796
Homologene: 41779
Nup62
Name: nucleoporin 62
Synonyms: D7Ertd649e, Nupc1, p62
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18226
HGNC: HGNC:8066
Homologene: 68773
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: Myhn-2, 5730504C04Rik, Myhn2, nonmuscle myosin heavy chain II-B, nonmuscle myosin heavy chain IIB, Myosin IIB, myosin IIB, NMHC-B, SMemb, Fltn, 9330167F11Rik, Fltn, NMHC II-B
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Baz1b
Name: bromodomain adjacent to zinc finger domain, 1B
Synonyms: WSTF, Wbscr9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22385
HGNC: HGNC:961
Homologene: 22651
Helb
Name: helicase (DNA) B
Synonyms: D10Ertd664e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 117599
Homologene: 50463
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, 9030205D12Rik, AD013, A330063D19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109151
Homologene: 11844
Zfp619
Name: zinc finger protein 619
Synonyms: 3000002G13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70227
Homologene: 133818
Rsf1
Name: remodeling and spacing factor 1
Synonyms: 4832420A03Rik, XAP8, Hbxap, C030033M12Rik, p325
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17847
Homologene: 40978
E2f8
Name: E2F transcription factor 8
Synonyms: 4432406C08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108961
Homologene: 11654
Jam3
Name: junction adhesion molecule 3
Synonyms: JAM-3, 1110002N23Rik, JAM-C, Jcam3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83964
Homologene: 11338
Xdh
Name: xanthine dehydrogenase
Synonyms: XO, Xox1, xanthine oxidase, Xox-1, Xor
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Lamb2
Name: laminin, beta 2
Synonyms: Lamb-2, npht, Lams
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16779
HGNC: HGNC:6487
Homologene: 1723
Syt9
Name: synaptotagmin IX
Synonyms: Sytv
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 60510
Homologene: 11062
T2
Name: brachyury 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21331
Homologene: 86977
Oprl1
Name: opioid receptor-like 1
Synonyms: MOR-C, morc, XOR1, NOP, nociceptin/ orphaninFQ receptor, LC132, N/OFQ receptor, ORL1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18389
HGNC: HGNC:8155
Homologene: 22609
Fbxo9
Name: f-box protein 9
Synonyms: 9030401P18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71538
Homologene: 8217
Fhip1b
Name: FHF complex subunit HOOK interacting protein 1B
Synonyms: Fam160a2, 4632419K20Rik, 6530415H11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74349
Homologene: 75329
Fbxl18
Name: F-box and leucine-rich repeat protein 18
Synonyms: B130019G13Rik, C330021B20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231863
Homologene: 41603
Mfsd2a
Name: MFSD2 lysolipid transporter A, lysophospholipid
Synonyms: major facilitator superfamily domain containing 2A, Mfsd2, 1700018O18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76574
Homologene: 19229
Mdh2
Name: malate dehydrogenase 2, NAD (mitochondrial)
Synonyms: Mor-1, Mor1, Mdh-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17448
HGNC: HGNC:6971
Homologene: 55938
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, Dnahc8, P1-Loop
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Midn
Name: midnolin
Synonyms: 3000003C15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 59090
Homologene: 32510
Tcf25
Name: transcription factor 25 (basic helix-loop-helix)
Synonyms: Nulp1, 1810041K11Rik, 1100001J13Rik, D8Ertd325e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66855
Homologene: 5701
Zswim4
Name: zinc finger SWIM-type containing 4
Synonyms: E130119J17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212168
Homologene: 18183
Smg5
Name: SMG5 nonsense mediated mRNA decay factor
Synonyms: Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229512
Homologene: 9095
Tmeff2
Name: transmembrane protein with EGF-like and two follistatin-like domains 2
Synonyms: 4832418D20Rik, 7630402F16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56363
Homologene: 9417
Ift172
Name: intraflagellar transport 172
Synonyms: wim, 4930553F24Rik, avc1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67661
Homologene: 15202
Amy1
Name: amylase 1, salivary
Synonyms: Amy-1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11722
Homologene: 20179
Lig1
Name: ligase I, DNA, ATP-dependent
Synonyms: mLigI, LigI
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16881
HGNC: HGNC:6598
Homologene: 197
Fstl5
Name: follistatin-like 5
Synonyms: 9130207J01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213262
Homologene: 10584
Ushbp1
Name: USH1 protein network component harmonin binding protein 1
Synonyms: 2210404N08Rik, MCC2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234395
Homologene: 12914
Tnn
Name: tenascin N
Synonyms: Tnw, tenascin-W
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329278
Homologene: 18634
Kcnh4
Name: potassium voltage-gated channel, subfamily H (eag-related), member 4
Synonyms: BEC2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380728
HGNC: HGNC:6253
Homologene: 8180
Tshz3
Name: teashirt zinc finger family member 3
Synonyms: Tsh3, A630038G13Rik, teashirt3, Zfp537
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243931
Homologene: 10835
Abca9
Name: ATP-binding cassette, sub-family A member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Slc8b1
Name: solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
Synonyms: NCLX, Slc24a6, NCKX6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 170756
Homologene: 41602
Dis3l
Name: DIS3 like exosome 3'-5' exoribonuclease
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 213550
Homologene: 15797
Rev3l
Name: REV3 like, DNA directed polymerase zeta catalytic subunit
Synonyms: Rev, Sez4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19714
HGNC: HGNC:9968
Homologene: 48147
Wdr91
Name: WD repeat domain 91
Synonyms: 9530020G05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101240
Homologene: 8562
Prkch
Name: protein kinase C, eta
Synonyms: Pkch
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18755
HGNC: HGNC:9403
Homologene: 84384
Zfp93
Name: zinc finger protein 93
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22755
Homologene: 117959
Zfp235
Name: zinc finger protein 235
Synonyms: 0610030O19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56525
Homologene: 122146
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329942
Homologene: 89034
Ggn
Name: gametogenetin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243897
Homologene: 45139
Slco1b2
Name: solute carrier organic anion transporter family, member 1b2
Synonyms: Oatp1b2, Slc21a10, mlst-1, Slc21a6, 7330442B20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28253
Homologene: 75119
Cyp3a57
Name: cytochrome P450, family 3, subfamily a, polypeptide 57
Synonyms: EG622127
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622127
Homologene: 135775
Serpina3f
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3F
Synonyms: antitrypsin, alpha-1 antiproteinasin, 2A1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238393
HGNC: HGNC:16
Homologene: 115927
Clcn4
Name: chloride channel, voltage-sensitive 4
Synonyms: Clc4-2, Clcn4-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12727
HGNC: HGNC:2022
Homologene: 68207
Sema5a
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Synonyms: 9130201M22Rik, Semaf, M-Sema D, semF
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20356
VEGA: 15
Homologene: 2949
Cadps2
Name: Ca2+-dependent activator protein for secretion 2
Synonyms: cpd2, Caps2, A230044C21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320405
Homologene: 23060
Ifi205
Name: interferon activated gene 205
Synonyms: D3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226695
Homologene: 115929
Psg26
Name: pregnancy-specific beta-1-glycoprotein 26
Synonyms: cea14, EG574429
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 574429
Homologene: 110989
Lilra6
Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
Synonyms: Pira3, 7M1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18726
Homologene: 134028
Mast1
Name: microtubule associated serine/threonine kinase 1
Synonyms: 9430008B02Rik, SAST170, SAST
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 56527
Homologene: 10543
Grik2
Name: glutamate receptor, ionotropic, kainate 2 (beta 2)
Synonyms: Glur6, Glurbeta2, C130030K03Rik, Glur-6
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14806
HGNC: HGNC:4580
Homologene: 40717
Mpped1
Name: metallophosphoesterase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223726
HGNC: HGNC:1306
Homologene: 15012
Sgce
Name: sarcoglycan, epsilon
Synonyms: e-SG
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20392
Homologene: 31205
Or2g7
Name: olfactory receptor family 2 subfamily G member 7
Synonyms: GA_x6K02T2PSCP-2515350-2516303, MOR256-19, Olfr130
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258480
Homologene: 105876
Smr3a
Name: submaxillary gland androgen regulated protein 3A
Synonyms: Smr1, Smr3, MSG3, MSG1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20599
Kcnk10
Name: potassium channel, subfamily K, member 10
Synonyms: 3010005K24Rik, Trek2, 1700024D23Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 72258
VEGA: 12
HGNC: HGNC:6273
Homologene: 11321
Or52ab7
Name: olfactory receptor family 52 subfamily AB member 7
Synonyms: GA_x6K02T2PBJ9-6037823-6038782, MOR23-5, MOR23-4P, Olfr598
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257975
Homologene: 132401
Or2t46
Name: olfactory receptor family 2 subfamily T member 46
Synonyms: MOR275-5, MOR275-11_p, GA_x6K02T2NKPP-844642-843680, Olfr325
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258261
Homologene: 133015
C1s2
Name: complement component 1, s subcomponent 2
Synonyms: Gm5077
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 317677
HGNC: HGNC:1247
Homologene: 1314
Cep112
Name: centrosomal protein 112
Synonyms: 8430407H02Rik, 1700029K01Rik, 1700001M19Rik, Ccdc46, Macoco
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76380
Homologene: 44915
Zfp663
Name: zinc finger protein 663
Synonyms: LOC381405, Gm1008
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381405
Homologene: 128277
Ulbp1
Name: UL16 binding protein 1
Synonyms: MULT1, A430108B07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77777
VEGA: 10
Homologene: 108274
Tmem184a
Name: transmembrane protein 184a
Synonyms: Sdmg1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231832
Homologene: 64815
Psg29
Name: pregnancy-specific beta-1-glycoprotein 29
Synonyms: cea17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 114872
Homologene: 83380
Sapcd1
Name: suppressor APC domain containing 1
Synonyms: Ng23, G7d
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78376
Homologene: 86703
Ighv1-43
Name: immunoglobulin heavy variable V1-43
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 629908
Mterf4
Name: mitochondrial transcription termination factor 4
Synonyms: Mterfd2, 4933412H03Rik, 1810059A23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 69821
Homologene: 45600
Mgam2-ps
Name: maltase-glucoamylase 2, pseudogene
Synonyms: Gm7254
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 638904
RP23-357H5.5
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
9130017K11Rik
Name: RIKEN cDNA 9130017K11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Dhx58os
Name: DExH-box helicase 58, opposite strand
Synonyms: Gm11547
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 50,979,556 bp
  • A to G, chromosome 1 at 93,305,873 bp
  • C to A, chromosome 1 at 160,120,618 bp
  • C to A, chromosome 1 at 174,015,008 bp
  • A to G, chromosome 2 at 165,353,811 bp
  • A to G, chromosome 2 at 181,715,718 bp
  • C to A, chromosome 3 at 37,232,504 bp
  • C to T, chromosome 3 at 76,410,494 bp
  • C to T, chromosome 3 at 88,355,725 bp
  • C to T, chromosome 3 at 113,569,377 bp
  • A to G, chromosome 4 at 122,950,509 bp
  • A to G, chromosome 4 at 128,338,522 bp
  • A to T, chromosome 5 at 31,272,116 bp
  • T to G, chromosome 5 at 88,008,103 bp
  • A to G, chromosome 5 at 120,524,287 bp
  • T to A, chromosome 5 at 135,216,904 bp
  • T to A, chromosome 5 at 135,783,409 bp
  • C to A, chromosome 5 at 139,808,002 bp
  • A to G, chromosome 5 at 142,886,085 bp
  • T to C, chromosome 5 at 145,349,426 bp
  • T to C, chromosome 6 at 4,674,534 bp
  • A to G, chromosome 6 at 23,599,479 bp
  • T to C, chromosome 6 at 34,910,791 bp
  • A to T, chromosome 6 at 40,825,993 bp
  • A to G, chromosome 6 at 107,568,707 bp
  • A to T, chromosome 6 at 115,994,376 bp
  • A to G, chromosome 6 at 124,635,639 bp
  • G to A, chromosome 6 at 141,657,557 bp
  • T to G, chromosome 7 at 3,914,383 bp
  • T to A, chromosome 7 at 7,291,437 bp
  • T to A, chromosome 7 at 13,311,318 bp
  • G to A, chromosome 7 at 17,208,631 bp
  • A to G, chromosome 7 at 18,475,310 bp
  • T to G, chromosome 7 at 24,142,184 bp
  • A to G, chromosome 7 at 24,275,411 bp
  • G to T, chromosome 7 at 29,172,196 bp
  • T to A, chromosome 7 at 36,771,190 bp
  • G to A, chromosome 7 at 39,537,387 bp
  • T to C, chromosome 7 at 44,829,025 bp
  • G to A, chromosome 7 at 48,875,170 bp
  • GCGGCGGCG to GCGGCGGCGTCGGCGGCG, chromosome 7 at 97,579,916 bp
  • A to T, chromosome 7 at 103,328,833 bp
  • A to T, chromosome 7 at 105,389,335 bp
  • G to A, chromosome 7 at 107,504,272 bp
  • C to T, chromosome 8 at 71,395,049 bp
  • C to T, chromosome 8 at 84,226,667 bp
  • T to C, chromosome 8 at 84,921,052 bp
  • T to C, chromosome 8 at 91,033,708 bp
  • A to G, chromosome 8 at 116,575,269 bp
  • T to C, chromosome 8 at 123,388,635 bp
  • A to G, chromosome 9 at 27,098,373 bp
  • A to C, chromosome 9 at 64,307,201 bp
  • G to A, chromosome 9 at 78,085,886 bp
  • A to G, chromosome 9 at 107,578,954 bp
  • G to A, chromosome 9 at 108,487,647 bp
  • G to A, chromosome 9 at 109,772,119 bp
  • C to T, chromosome 10 at 7,447,391 bp
  • T to C, chromosome 10 at 19,869,332 bp
  • T to A, chromosome 10 at 39,823,578 bp
  • T to C, chromosome 10 at 49,132,745 bp
  • T to A, chromosome 10 at 80,150,184 bp
  • A to G, chromosome 10 at 120,110,881 bp
  • G to C, chromosome 11 at 23,488,982 bp
  • A to G, chromosome 11 at 58,581,629 bp
  • GGCTGCTGCTGCTGCTGC to GGCTGCTGCTGCTGC, chromosome 11 at 67,946,231 bp
  • A to G, chromosome 11 at 68,798,371 bp
  • T to C, chromosome 11 at 100,697,071 bp
  • A to T, chromosome 11 at 100,746,833 bp
  • T to C, chromosome 11 at 108,434,236 bp
  • T to C, chromosome 11 at 110,136,073 bp
  • T to C, chromosome 12 at 73,702,893 bp
  • A to G, chromosome 12 at 98,440,687 bp
  • G to A, chromosome 12 at 104,217,055 bp
  • A to T, chromosome 12 at 114,946,225 bp
  • T to A, chromosome 15 at 32,679,186 bp
  • A to T, chromosome 15 at 83,796,706 bp
  • T to A, chromosome 16 at 92,644,347 bp
  • A to G, chromosome 17 at 8,413,069 bp
  • A to G, chromosome 17 at 12,403,089 bp
  • A to G, chromosome 17 at 30,663,301 bp
  • A to T, chromosome 17 at 35,026,451 bp
  • A to T, chromosome 17 at 38,067,747 bp
  • A to G, chromosome 17 at 67,737,682 bp
  • A to T, chromosome 17 at 73,898,970 bp
  • A to G, chromosome 19 at 59,459,246 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4977 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042572-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.