Strain Name:
C57BL/6J-MtgxR5084Btlr/Mmmh
Stock Number:
042673-MU
Citation ID:
RRID:MMRRC_042673-MU
Other Names:
R5084 (G1), C57BL/6J-MtgxR5084Btlr
Major Collection:

Gene Information

Cd4
Name: CD4 antigen
Synonyms: L3T4, Ly-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12504
HGNC: HGNC:1678
Homologene: 513
Matr3
Name: matrin 3
Synonyms: D030046F20Rik, 2810017I02Rik, 1110061A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17184
HGNC: HGNC:6912
Homologene: 7830
Smarca4
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms: SNF2beta, Brg1, SW1/SNF, b2b692Clo, b2b508.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20586
Homologene: 135927
Plcb4
Name: phospholipase C, beta 4
Synonyms: A930039J07Rik, C230058B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18798
HGNC: HGNC:9059
Homologene: 8471
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, Zap3, A930013E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56531
Homologene: 87707
Ldlrad3
Name: low density lipoprotein receptor class A domain containing 3
Synonyms: Lrad3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241576
Homologene: 18377
Dapk3
Name: death-associated protein kinase 3
Synonyms: ZIP kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13144
VEGA: 10
HGNC: HGNC:2676
Homologene: 20353
Vcl
Name: vinculin
Synonyms: metavinculin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 22330
VEGA: 14
Homologene: 7594
Fbrsl1
Name: fibrosin-like 1
Synonyms: LOC381668, 2410025L10Rik, Gm29766
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381668
Homologene: 45966
Sipa1l3
Name: signal-induced proliferation-associated 1 like 3
Synonyms: 2610511M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74206
Homologene: 77938
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20624
Homologene: 3133
Crot
Name: carnitine O-octanoyltransferase
Synonyms: 1200003H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74114
HGNC: HGNC:2366
Homologene: 10899
Pip4k2b
Name: phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Synonyms: c11, PI5P4Kbeta, Pip5k2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 108083
HGNC: HGNC:8998
Homologene: 2634
Peg3
Name: paternally expressed 3
Synonyms: Pw1, Zfp102, End4, Gcap4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18616
HGNC: HGNC:8826
Homologene: 31363
2210016L21Rik
Name: RIKEN cDNA 2210016L21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72357
Homologene: 11285
Lpin1
Name: lipin 1
Synonyms: Lipin1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14245
VEGA: 12
Homologene: 9266
Olfm3
Name: olfactomedin 3
Synonyms: optimedin, B230206G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229759
Homologene: 17103
Nktr
Name: natural killer tumor recognition sequence
Synonyms: D9Wsu172e, 5330401F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Rbl2
Name: RB transcriptional corepressor like 2
Synonyms: Rb2, p130, retinoblastoma-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19651
HGNC: HGNC:9894
Homologene: 4098
Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Synonyms: LR11, mSorLA, 2900010L19Rik, Sorla
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20660
Homologene: 2336
Akap7
Name: A kinase (PRKA) anchor protein 7
Synonyms: Akap18, AKAP15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432442
HGNC: HGNC:377
Homologene: 49463
Zfp236
Name: zinc finger protein 236
Synonyms: LOC240456
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 329002
Homologene: 7198
Pask
Name: PAS domain containing serine/threonine kinase
Synonyms: Paskin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269224
Homologene: 9038
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171395
Homologene: 51376
Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
Synonyms: dapper2, 2900084M21Rik, Frd2, Dpr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240025
VEGA: 17
Homologene: 18237
Anpep
Name: alanyl (membrane) aminopeptidase
Synonyms: Cd13, aminopeptidase N, Apn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16790
HGNC: HGNC:500
Homologene: 68163
Spata31d1c
Name: spermatogenesis associated 31 subfamily D, member 1C
Synonyms: Fam75d1c, 4932441B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238683
VEGA: 13
Nell1
Name: NEL-like 1
Synonyms: B230343H07Rik, l7R6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 338352
HGNC: HGNC:7750
Homologene: 4486
Vmn2r57
Name: vomeronasal 2, receptor 57
Synonyms: EG269902
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269902
Homologene: 104832
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Aste1
Name: asteroid homolog 1
Synonyms: 1100001A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66595
Homologene: 130666
Flg
Name: filaggrin
Synonyms: profilaggrin, fillagrin, ft
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14246
VEGA: 3
Syde2
Name: synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
Synonyms: C430017H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214804
Homologene: 19035
Acpp
Name: acid phosphatase, prostate
Synonyms: PAP, A030005E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56318
HGNC: HGNC:125
Homologene: 55552
Topaz1
Name: testis and ovary specific PAZ domain containing 1
Synonyms: Gm9524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 671232
VEGA: 9
Homologene: 19835
A530053G22Rik
Name: RIKEN cDNA A530053G22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 208079
Or7g17
Name: olfactory receptor family 7 subfamily G member 17
Synonyms: GA_x6K02T2PVTD-12599710-12600648, MOR147-1, Olfr829
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 259070
Homologene: 138324
Vmn2r92
Name: vomeronasal 2, receptor 92
Synonyms: EG627111
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627111
Homologene: 115024
Taar5
Name: trace amine-associated receptor 5
Synonyms: LOC215854
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215854
Homologene: 20850
Hs3st4
Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 4
Synonyms: Gm6915
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628779
HGNC: HGNC:5200
Homologene: 82444
Fscn2
Name: fascin actin-bundling protein 2
Synonyms: C630046B20Rik, ahl8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 238021
HGNC: HGNC:3960
Homologene: 22722
Rasgef1c
Name: RasGEF domain family, member 1C
Synonyms: 9130006A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74563
Homologene: 17918
Or10ak11
Name: olfactory receptor family 10 subfamily AK member 11
Synonyms: GA_x6K02T2QD9B-18703033-18703986, MOR259-6, MOR259-11, Olfr1333
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258265
Homologene: 134082
Or2a20
Name: olfactory receptor family 2 subfamily A member 2
Synonyms: GA_x6K02T2P3E9-4341246-4340281, MOR261-10, Olfr434
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258366
Homologene: 133700
Opcml
Name: opioid binding protein/cell adhesion molecule-like
Synonyms: Obcam, LOC235104, 2900075O15Rik, B930023M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330908
HGNC: HGNC:8143
Homologene: 55663
H2-Ob
Name: histocompatibility 2, O region beta locus
Synonyms: Ob, H-2I, H2-IAb2, H2-Ab, H-2Ob, H2-Ab2, A-beta2, A-beta-2, vic1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15002
HGNC: HGNC:4937
Homologene: 1602
Timm44
Name: translocase of inner mitochondrial membrane 44
Synonyms: Tim44, Mimt44, D8Ertd118e, 0710005E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21856
Homologene: 4631
Or5h25
Name: olfactory receptor family 5 subfamily H member 25
Synonyms: GA_x54KRFPKG5P-55338697-55337768, MOR113-7P, MOR183-7P, MOR113-7P, Olfr1540-ps1, Olfr193
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 257972
Homologene: 128162
Plk5
Name: polo like kinase 5
Synonyms: 6330514A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216166
Homologene: 28072
Ston1
Name: stonin 1
Synonyms: 4921524J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77057
Homologene: 122152
Csn3
Name: casein kappa
Synonyms: CSN10, Csnk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12994
HGNC: HGNC:2446
Homologene: 3818
Ccdc183
Name: coiled-coil domain containing 183
Synonyms: Cccd183, 4921530D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77058
Homologene: 50023
Smpd1
Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Synonyms: A-SMase, aSMase, ASM, acid sphingomyelinase, Zn-SMase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20597
Homologene: 457
Or7e173
Name: olfactory receptor family 7 subfamily E member 173
Synonyms: GA_x6K02T2PVTD-13768406-13767468, MOR145-5, Olfr866
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258551
HGNC: HGNC:8396
Homologene: 133687
Zfp786
Name: zinc finger protein 786
Synonyms: A730012O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330301
Homologene: 51849
1700111E14Rik
Name: RIKEN cDNA 1700111E14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Tex37
Name: testis expressed 37
Synonyms: 1700011F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74221
Homologene: 17643
Pou4f3
Name: POU domain, class 4, transcription factor 3
Synonyms: Brn-3.1, Brn3.1, Brn3c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 18998
HGNC: HGNC:9220
Homologene: 2023
Tas2r114
Name: taste receptor, type 2, member 114
Synonyms: Tas2r14, T2R14, mGR14, mt2r46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387346
Homologene: 128355
Hmgcs1
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Synonyms: B130032C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 208715
VEGA: 13
HGNC: HGNC:5007
Homologene: 1609
Pcdha6
Name: protocadherin alpha 6
Synonyms: Cnr2, Crnr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12937
Homologene: 75098
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: G4.8, Dnl1ll, 2310005K03Rik, Dnase1ll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Gm6214
Name: predicted gene 6214
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 621343
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 93,322,097 bp
  • G to A, chromosome 2 at 25,608,790 bp
  • G to A, chromosome 2 at 102,069,984 bp
  • A to G, chromosome 2 at 136,002,651 bp
  • T to C, chromosome 3 at 93,277,615 bp
  • T to C, chromosome 3 at 114,904,553 bp
  • A to G, chromosome 3 at 140,839,123 bp
  • AGTTC to AGTTCGTTC, chromosome 3 at 146,001,409 bp
  • A to G, chromosome 4 at 118,829,570 bp
  • G to T, chromosome 5 at 8,969,994 bp
  • A to G, chromosome 5 at 87,928,243 bp
  • G to A, chromosome 5 at 110,379,406 bp
  • A to T, chromosome 5 at 114,946,402 bp
  • T to C, chromosome 6 at 36,974,886 bp
  • T to C, chromosome 6 at 43,217,660 bp
  • T to C, chromosome 6 at 47,820,019 bp
  • T to C, chromosome 6 at 60,402,152 bp
  • A to G, chromosome 6 at 70,915,704 bp
  • A to T, chromosome 6 at 124,870,439 bp
  • A to T, chromosome 6 at 131,689,288 bp
  • T to C, chromosome 7 at 6,707,849 bp
  • G to A, chromosome 7 at 29,348,575 bp
  • C to A, chromosome 7 at 41,426,550 bp
  • T to C, chromosome 7 at 50,249,666 bp
  • C to A, chromosome 7 at 79,826,870 bp
  • T to C, chromosome 7 at 105,556,978 bp
  • G to T, chromosome 7 at 124,397,295 bp
  • G to A, chromosome 8 at 4,266,634 bp
  • C to T, chromosome 8 at 91,115,131 bp
  • T to A, chromosome 9 at 18,857,336 bp
  • T to A, chromosome 9 at 20,027,255 bp
  • T to C, chromosome 9 at 21,660,763 bp
  • T to G, chromosome 9 at 28,675,299 bp
  • T to C, chromosome 9 at 41,976,377 bp
  • T to A, chromosome 9 at 104,326,917 bp
  • T to A, chromosome 9 at 105,397,687 bp
  • T to C, chromosome 9 at 121,748,110 bp
  • T to A, chromosome 9 at 122,748,818 bp
  • T to A, chromosome 10 at 23,970,938 bp
  • T to A, chromosome 10 at 25,279,742 bp
  • C to A, chromosome 10 at 80,358,889 bp
  • C to A, chromosome 10 at 81,190,318 bp
  • T to C, chromosome 11 at 8,942,004 bp
  • A to G, chromosome 11 at 49,969,505 bp
  • G to A, chromosome 11 at 97,719,743 bp
  • A to G, chromosome 11 at 102,869,158 bp
  • C to T, chromosome 11 at 115,984,157 bp
  • A to G, chromosome 11 at 120,361,860 bp
  • A to G, chromosome 12 at 16,576,982 bp
  • T to G, chromosome 12 at 85,029,321 bp
  • C to A, chromosome 13 at 65,035,130 bp
  • T to C, chromosome 13 at 119,699,984 bp
  • G to T, chromosome 14 at 21,008,959 bp
  • C to T, chromosome 16 at 59,110,073 bp
  • A to T, chromosome 17 at 14,197,952 bp
  • A to G, chromosome 17 at 18,185,177 bp
  • G to T, chromosome 17 at 34,241,128 bp
  • A to T, chromosome 17 at 88,636,574 bp
  • G to A, chromosome 18 at 35,582,082 bp
  • A to T, chromosome 18 at 36,968,963 bp
  • A to T, chromosome 18 at 42,395,868 bp
  • A to G, chromosome 18 at 82,609,431 bp
  • C to T, chromosome X at 74,277,038 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5084 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042673-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.