Strain Name:
C57BL/6J-MtgxR5352Btlr/Mmmh
Stock Number:
042931-MU
Citation ID:
RRID:MMRRC_042931-MU
Other Names:
R5352 (G1), C57BL/6J-MtgxR5352Btlr
Major Collection:

Gene Information

Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Ank-2, Ankyrin-2, Ankyrin-B, Gm4392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Snx2
Name: sorting nexin 2
Synonyms: 0610030A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67804
VEGA: 18
Homologene: 2332
Thbs4
Name: thrombospondin 4
Synonyms: TSP-4, TSP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21828
Homologene: 20691
Pdxdc1
Name: pyridoxal-dependent decarboxylase domain containing 1
Synonyms: 2210010A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 94184
Homologene: 22858
Uhrf1bp1
Name: UHRF1 (ICBP90) binding protein 1
Synonyms: 1110020K19Rik, F830021D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224648
Homologene: 9816
Rprd1b
Name: regulation of nuclear pre-mRNA domain containing 1B
Synonyms: 2810446G03Rik, 2610304G08Rik, Crept
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70470
Homologene: 41426
Gm12183
Name: predicted gene 12183
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432554
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: 5730509K17Rik, b2b1035Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231214
Homologene: 18159
Zfp160
Name: zinc finger protein 160
Synonyms: 6720480D16Rik, 6720480D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224585
VEGA: 17
Homologene: 137372
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Iws1
Name: IWS1, SUPT6 interacting protein
Synonyms: 1700069O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 73473
Homologene: 134421
Med13
Name: mediator complex subunit 13
Synonyms: Trap240, 1110067M05Rik, Thrap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327987
Homologene: 21067
Zfp981
Name: zinc finger protein 981
Synonyms: Gm13247
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100041433
Homologene: 133076
Rasa3
Name: RAS p21 protein activator 3
Synonyms: GAPIII activator 3, Ras GTPase-activating protein III, GAPIII, R-Ras gap, scat, hlb381
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19414
Homologene: 7217
Btnl9
Name: butyrophilin-like 9
Synonyms: D330012D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237754
Homologene: 68540
Hk1
Name: hexokinase 1
Synonyms: Hk-1, mHk1-s, Hk1-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Man2a1
Name: mannosidase 2, alpha 1
Synonyms: Mana-2, Mana2, Map-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17158
HGNC: HGNC:6824
Homologene: 1777
Ola1
Name: Obg-like ATPase 1
Synonyms: 2510025G09Rik, 2810405J23Rik, 2810409H07Rik, Gtpbp9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67059
Homologene: 5361
Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
Synonyms: Plekhe1, Phlpp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98432
Homologene: 11015
Slc39a6
Name: solute carrier family 39 (metal ion transporter), member 6
Synonyms: Ermelin, Zip6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 106957
Homologene: 8199
Agtpbp1
Name: ATP/GTP binding protein 1
Synonyms: Nna1, 2900054O13Rik, 1700020N17Rik, 5730402G09Rik, 4930445M19Rik, 2310001G17Rik, Ccp1, atms
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67269
Homologene: 9067
Sag
Name: S-antigen, retina and pineal gland (arrestin)
Synonyms: A930001K18Rik, rod arrestin, Arr1, arrestin 1, visual arrestin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20215
Homologene: 455
Chst1
Name: carbohydrate sulfotransferase 1
Synonyms: KSGAL6ST, C6ST, 2610008E20Rik, GST-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76969
HGNC: HGNC:1969
Homologene: 2711
Zfpm2
Name: zinc finger protein, multitype 2
Synonyms: FOG-2, FOG2, B330005D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22762
VEGA: 15
Homologene: 8008
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Tnni1
Name: troponin I, skeletal, slow 1
Synonyms: 2700018B22Rik, ssTnI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21952
Homologene: 2462
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mass1, Mgr1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: oxygen-regulated protein 1, Orp1, mG145, Dcdc3, Rp1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19888
Homologene: 4564
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Vmn1r48
Name: vomeronasal 1 receptor 48
Synonyms: V1ra3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113845
Homologene: 137651
F830045P16Rik
Name: RIKEN cDNA F830045P16 gene
Synonyms: Sirpb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228592
Homologene: 136180
Tmem208
Name: transmembrane protein 208
Synonyms: 2610030K20Rik, 1700006C06Rik, Hspc171
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66320
Homologene: 40930
Corin
Name: corin, serine peptidase
Synonyms: Lrp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 53419
Homologene: 4804
Grm5
Name: glutamate receptor, metabotropic 5
Synonyms: mGluR5, Gprc1e, 6430542K11Rik, Glu5R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 108071
HGNC: HGNC:4597
Homologene: 37354
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68553
Homologene: 130754
Ppp1r36
Name: protein phosphatase 1, regulatory subunit 36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 210762
VEGA: 12
Homologene: 52094
Nup210
Name: nucleoporin 210
Synonyms: gp210, gp190, Pom210
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54563
Homologene: 41286
Flnc
Name: filamin C, gamma
Synonyms: Fln2, 1110055E19Rik, actin binding protein 280
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Tmf1
Name: TATA element modulatory factor 1
Synonyms: LOC232286, 7030402D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232286
Homologene: 133801
Kdm4d
Name: lysine (K)-specific demethylase 4D
Synonyms: Jmjd2d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244694
Homologene: 69244
Blk
Name: B lymphoid kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12143
VEGA: 14
HGNC: HGNC:1057
Homologene: 1297
Meioc
Name: meiosis specific with coiled-coil domain
Synonyms: LOC380729, LOC268491, Gm1564
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268491
Homologene: 19559
Sec14l4
Name: SEC14-like lipid binding 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103655
Homologene: 68807
Iqca
Name: IQ motif containing with AAA domain
Synonyms: 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74918
Homologene: 49784
Foxj1
Name: forkhead box J1
Synonyms: Hfh4, FKHL-13, HFH-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15223
HGNC: HGNC:3816
Homologene: 1117
Nlrp4e
Name: NLR family, pyrin domain containing 4E
Synonyms: Nalp-epsilon, Nalp4e, 4930406H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 446099
Homologene: 75315
Dlgap1
Name: DLG associated protein 1
Synonyms: SAPAP1, DAP-1 beta, D17Bwg0511e, GKAP/SAPAP, Sapap1, 4933422O14Rik, Gkap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224997
HGNC: HGNC:2905
Homologene: 31258
Atp6ap1l
Name: ATPase, H+ transporting, lysosomal accessory protein 1-like
Synonyms: EG435376
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 435376
Homologene: 28130
Mrgpre
Name: MAS-related GPR, member E
Synonyms: MrgE, C130069N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244238
Homologene: 18469
A630010A05Rik
Name: RIKEN cDNA A630010A05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 545280
Vmn1r89
Name: vomeronasal 1 receptor 89
Synonyms: V1rj2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171260
Homologene: 74345
Trim31
Name: tripartite motif-containing 31
Synonyms: HCG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224762
Homologene: 17137
Lipi
Name: lipase, member I
Synonyms: D930038D03Rik, lpd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320355
Homologene: 77864
Slc9a3r2
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
Synonyms: Nherf2, Octs2, Tka-1, Sip-1, E3karp, 1200011K07Rik, Sip1, 2010007A20Rik, 0610011L07Rik, Sryip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 65962
VEGA: 17
Homologene: 56962
Dusp29
Name: dual specificity phosphatase 29
Synonyms: EG435391, Dupd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 435391
VEGA: 14
Homologene: 51120
Tor3a
Name: torsin family 3, member A
Synonyms: Adir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 30935
Homologene: 23359
Gm27047
Name: predicted gene, 27047
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Dnal1
Name: dynein, axonemal, light chain 1
Synonyms: E330027P08Rik, 1700010H15Rik, Dnal1, Dnalc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 105000
Homologene: 34623
Sat2
Name: spermidine/spermine N1-acetyl transferase 2
Synonyms: SSAT2, SSAT-2, 2610016A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69215
Homologene: 44215
Gm28557
Name: predicted gene 28557
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Mir6965
Name: microRNA 6965
Synonyms: mmu-mir-6965
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 102465582
VEGA: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 4,347,098 bp
  • G to T, chromosome 1 at 87,812,993 bp
  • A to T, chromosome 1 at 90,130,196 bp
  • A to G, chromosome 1 at 106,172,725 bp
  • A to G, chromosome 1 at 135,805,592 bp
  • T to G, chromosome 1 at 156,674,193 bp
  • T to C, chromosome 2 at 73,099,330 bp
  • A to G, chromosome 2 at 92,613,365 bp
  • T to A, chromosome 2 at 129,472,901 bp
  • A to G, chromosome 2 at 158,058,736 bp
  • C to A, chromosome 3 at 127,498,991 bp
  • C to A, chromosome 4 at 146,537,005 bp
  • G to T, chromosome 5 at 43,706,213 bp
  • C to T, chromosome 5 at 72,305,033 bp
  • A to G, chromosome 6 at 29,449,318 bp
  • G to T, chromosome 6 at 90,036,147 bp
  • A to T, chromosome 6 at 91,069,316 bp
  • A to G, chromosome 6 at 97,176,809 bp
  • G to A, chromosome 6 at 130,631,019 bp
  • T to G, chromosome 7 at 13,219,357 bp
  • T to C, chromosome 7 at 23,353,173 bp
  • A to G, chromosome 7 at 88,074,850 bp
  • T to A, chromosome 7 at 141,864,558 bp
  • A to C, chromosome 7 at 143,781,094 bp
  • A to C, chromosome 8 at 13,631,778 bp
  • A to G, chromosome 8 at 105,328,431 bp
  • A to G, chromosome 9 at 14,464,358 bp
  • G to A, chromosome 9 at 106,061,544 bp
  • A to C, chromosome 9 at 108,961,411 bp
  • A to T, chromosome 10 at 62,304,770 bp
  • C to T, chromosome 11 at 4,043,868 bp
  • T to C, chromosome 11 at 48,752,162 bp
  • T to C, chromosome 11 at 49,178,840 bp
  • A to T, chromosome 11 at 69,622,315 bp
  • T to A, chromosome 11 at 86,301,468 bp
  • A to G, chromosome 11 at 102,668,427 bp
  • A to T, chromosome 11 at 102,675,313 bp
  • T to C, chromosome 11 at 116,334,079 bp
  • A to T, chromosome 12 at 52,796,097 bp
  • T to C, chromosome 12 at 76,428,083 bp
  • T to C, chromosome 12 at 84,136,548 bp
  • G to A, chromosome 13 at 59,473,746 bp
  • T to A, chromosome 13 at 67,074,162 bp
  • T to C, chromosome 13 at 81,494,657 bp
  • A to C, chromosome 13 at 90,883,756 bp
  • T to C, chromosome 13 at 92,763,590 bp
  • G to A, chromosome 14 at 21,677,023 bp
  • A to G, chromosome 14 at 63,375,971 bp
  • T to A, chromosome 15 at 40,870,542 bp
  • T to C, chromosome 16 at 13,840,311 bp
  • T to G, chromosome 16 at 14,618,701 bp
  • C to T, chromosome 16 at 18,795,897 bp
  • C to A, chromosome 16 at 75,562,333 bp
  • A to G, chromosome 17 at 21,026,852 bp
  • A to G, chromosome 17 at 24,243,273 bp
  • C to T, chromosome 17 at 24,642,255 bp
  • G to A, chromosome 17 at 27,887,515 bp
  • T to A, chromosome 17 at 36,899,918 bp
  • T to C, chromosome 17 at 64,731,246 bp
  • A to T, chromosome 17 at 70,718,203 bp
  • A to T, chromosome 18 at 24,601,036 bp
  • A to T, chromosome 18 at 32,083,404 bp
  • A to G, chromosome 18 at 53,197,925 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5352 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042931-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.