Strain Name:
C57BL/6J-MtgxR5640Btlr
Stock Number:
043289-MU
Citation ID:
RRID:MMRRC_043289-MU
Other Names:
R5640 (G1)
Major Collection:

Gene Information

Sez6
Name: seizure related gene 6
Synonyms: sez-6, D11Bhm177e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20370
Homologene: 10948
Prdm16
Name: PR domain containing 16
Synonyms: Mel1, 5730557K01Rik, line 27, csp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 70673
Homologene: 11139
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, 5430433L24Rik, D630035I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 108829
Homologene: 3129
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, XRCC7, DNA-PK, DOXNPH, dxnph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Fam110b
Name: family with sequence similarity 110, member B
Synonyms: 1700012H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242297
Homologene: 17518
Lrsam1
Name: leucine rich repeat and sterile alpha motif containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227738
Homologene: 44526
Eprs
Name: glutamyl-prolyl-tRNA synthetase
Synonyms: 2410081F06Rik, 3010002K18Rik, Qprs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 107508
HGNC: HGNC:3418
Homologene: 5870
Gse1
Name: genetic suppressor element 1, coiled-coil protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382034
Homologene: 40964
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, AD013, A330063D19Rik, 9030205D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109151
Homologene: 11844
Arntl
Name: aryl hydrocarbon receptor nuclear translocator-like
Synonyms: Arnt3, MOP3, Bmal1, bHLHe5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11865
HGNC: HGNC:701
Homologene: 910
Themis
Name: thymocyte selection associated
Synonyms: E430004N04Rik, Gasp, Tsepa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 210757
Homologene: 72287
Rad1
Name: RAD1 checkpoint DNA exonuclease
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19355
HGNC: HGNC:9806
Homologene: 37695
Fuca2
Name: fucosidase, alpha-L- 2, plasma
Synonyms: 5530401P20Rik, 0610025O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66848
HGNC: HGNC:4008
Homologene: 119
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Actl6a
Name: actin-like 6A
Synonyms: Actl6, Baf53a, 2810432C06Rik, ARP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56456
Homologene: 55811
Med6
Name: mediator complex subunit 6
Synonyms: 1500012F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 69792
Homologene: 3990
Tmem68
Name: transmembrane protein 68
Synonyms: 2010300G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72098
Homologene: 12440
Fads1
Name: fatty acid desaturase 1
Synonyms: 0710001O03Rik, A930006B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76267
VEGA: 19
HGNC: HGNC:3574
Homologene: 22753
Dpys
Name: dihydropyrimidinase
Synonyms: DHPase, 1300004I01Rik, 1200017I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64705
HGNC: HGNC:3013
Homologene: 20359
Nrbp1
Name: nuclear receptor binding protein 1
Synonyms: B230344L17Rik, Nrbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 192292
HGNC: HGNC:7993
Homologene: 8373
Pnpla7
Name: patatin-like phospholipase domain containing 7
Synonyms: E430013P11Rik, NRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241274
Homologene: 62431
Zfp418
Name: zinc finger protein 418
Synonyms: A230102I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232854
Homologene: 119890
Alx3
Name: aristaless-like homeobox 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11694
HGNC: HGNC:449
Homologene: 4737
Rnf135
Name: ring finger protein 135
Synonyms: U 2-3-0, MGC13061, 0610037N03Rik, 2410006N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71956
Homologene: 12427
Ptchd4
Name: patched domain containing 4
Synonyms: 3110082D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627626
VEGA: 17
Homologene: 78322
Nlrc5
Name: NLR family, CARD domain containing 5
Synonyms: AI451557
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 434341
Homologene: 88935
Gm8251
Name: predicted gene 8251
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Olfr1338
Name: olfactory receptor 1338
Synonyms: GA_x6K02T2QD9B-18795136-18796077, MOR259-4P, MOR259-4P, MOR259-9, Olfr1524-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258259
Homologene: 115537
Sik2
Name: salt inducible kinase 2
Synonyms: G630080D20Rik, Snf1lk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235344
Homologene: 22875
Atp13a4
Name: ATPase type 13A4
Synonyms: 4631413J11Rik, 9330174J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224079
Homologene: 75330
Pop7
Name: processing of precursor 7, ribonuclease P family, (S. cerevisiae)
Synonyms: 0610037N12Rik, Rpp20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74097
Homologene: 4262
Dlg5
Name: discs large MAGUK scaffold protein 5
Synonyms: 4933429D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71228
HGNC: HGNC:2904
Homologene: 3486
Lrrc66
Name: leucine rich repeat containing 66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231296
Homologene: 51944
Ppm1h
Name: protein phosphatase 1H (PP2C domain containing)
Synonyms: ARHCL1, A430075L18Rik, C030002B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 319468
Homologene: 18537
Lipo4
Name: lipase, member O4
Synonyms: Gm6857
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 628236
Homologene: 103863
Armc2
Name: armadillo repeat containing 2
Synonyms: 2610018I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213402
Homologene: 41848
Thsd7b
Name: thrombospondin, type I, domain containing 7B
Synonyms: 1700074E13Rik, D130067I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210417
Homologene: 18180
Kif19a
Name: kinesin family member 19A
Synonyms: N-8 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 286942
Homologene: 17709
Vwa5b2
Name: von Willebrand factor A domain containing 5B2
Synonyms: EG328644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 328643
Homologene: 28056
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 626596
Homologene: 75047
Vmn2r107
Name: vomeronasal 2, receptor 107
Synonyms: V2r6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22312
Homologene: 129750
Cyp3a16
Name: cytochrome P450, family 3, subfamily a, polypeptide 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13114
HGNC: HGNC:2638
Homologene: 133568
Ace
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Synonyms: CD143
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11421
HGNC: HGNC:2707
Homologene: 37351
Pde3a
Name: phosphodiesterase 3A, cGMP inhibited
Synonyms: A930022O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54611
HGNC: HGNC:8778
Homologene: 708
Sh3rf3
Name: SH3 domain containing ring finger 3
Synonyms: 4831416G18Rik, Sh3md4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237353
Homologene: 77551
Olfr739
Name: olfactory receptor 739
Synonyms: GA_x6K02T2PMLR-6121675-6122604, MOR106-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258663
Homologene: 121549
Dpysl2
Name: dihydropyrimidinase-like 2
Synonyms: Ulip2, Crmp2, TOAD-64, DRP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12934
HGNC: HGNC:3014
Homologene: 74392
Pgap6
Name: post-glycosylphosphatidylinositol attachment to proteins 6
Synonyms: M83, Rxylt1, Tmem8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 60455
Homologene: 10944
Gnas
Name: GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
Synonyms: Gnas1, Gs-alpha, Gs alpha, G alpha s, Nesp55, neuroendocrine-specific Golgi protein p55 isoform 1, XLalphas, P2, P3, P1, Gsa, Nesp, Gnasxl, Nespl, Oedsml, Galphas, SCG6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14683
HGNC: HGNC:4392
Homologene: 55534
Ipp
Name: IAP promoted placental gene
Synonyms: D4Jhu8, Mipp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16351
HGNC: HGNC:6108
Homologene: 4309
Brdt
Name: bromodomain, testis-specific
Synonyms: 7420412D09Rik, Brd6, Fsrg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 114642
HGNC: HGNC:1105
Homologene: 21064
Hoxc10
Name: homeobox C10
Synonyms: Hox-3.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 209448
HGNC: HGNC:5122
Homologene: 9680
Adamts8
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
Synonyms: METH2, METH-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 30806
HGNC: HGNC:224
Homologene: 5108
Ces3a
Name: carboxylesterase 3A
Synonyms: Es-male carboxylesterase, Es31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382053
HGNC: HGNC:1865
Homologene: 84407
Olfr1256
Name: olfactory receptor 1256
Synonyms: GA_x6K02T2Q125-51276848-51275928, MOR231-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258985
Homologene: 128157
B4galt2
Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 53418
HGNC: HGNC:925
Homologene: 2804
Atp10d
Name: ATPase, class V, type 10D
Synonyms: IMAGE:1069176, D5Buc24e, 9830145H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231287
Fbxl21
Name: F-box and leucine-rich repeat protein 21
Synonyms: FBXL3B, FBL3B, D630045D17Rik, Psttm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 213311
Homologene: 78724
Aga
Name: aspartylglucosaminidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11593
HGNC: HGNC:318
Homologene: 13
Prdm6
Name: PR domain containing 6
Synonyms: LOC225518, PRISM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225518
HGNC: HGNC:9350
Homologene: 79756
Rnft1
Name: ring finger protein, transmembrane 1
Synonyms: 0610013E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76892
Homologene: 41110
Agmat
Name: agmatine ureohydrolase (agmatinase)
Synonyms: 5033405N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75986
Homologene: 99855
Dhrs9
Name: dehydrogenase/reductase (SDR family) member 9
Synonyms: C730025I08Rik, Rdh15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241452
Homologene: 26079
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 44,061,927 bp
  • T to A, chromosome 1 at 130,116,671 bp
  • A to G, chromosome 1 at 185,374,184 bp
  • C to T, chromosome 2 at 25,003,001 bp
  • T to A, chromosome 2 at 32,945,852 bp
  • C to A, chromosome 2 at 69,394,478 bp
  • T to A, chromosome 2 at 89,835,938 bp
  • C to A, chromosome 2 at 174,284,971 bp
  • A to G, chromosome 3 at 32,718,050 bp
  • C to A, chromosome 3 at 107,600,661 bp
  • A to T, chromosome 4 at 3,569,512 bp
  • T to G, chromosome 4 at 5,798,689 bp
  • T to G, chromosome 4 at 116,520,689 bp
  • T to G, chromosome 4 at 117,873,998 bp
  • T to A, chromosome 4 at 118,753,789 bp
  • T to A, chromosome 4 at 141,755,823 bp
  • T to C, chromosome 4 at 154,341,910 bp
  • C to T, chromosome 5 at 31,249,585 bp
  • T to G, chromosome 5 at 72,247,209 bp
  • A to T, chromosome 5 at 73,608,634 bp
  • A to T, chromosome 5 at 107,359,308 bp
  • T to C, chromosome 5 at 137,502,059 bp
  • T to A, chromosome 5 at 145,452,823 bp
  • A to G, chromosome 6 at 141,483,915 bp
  • T to A, chromosome 7 at 7,181,981 bp
  • C to T, chromosome 7 at 113,308,681 bp
  • T to C, chromosome 8 at 53,511,884 bp
  • T to A, chromosome 8 at 91,036,562 bp
  • A to G, chromosome 8 at 94,475,793 bp
  • T to A, chromosome 8 at 105,051,745 bp
  • A to G, chromosome 8 at 120,562,677 bp
  • T to C, chromosome 9 at 30,956,500 bp
  • T to C, chromosome 9 at 50,915,506 bp
  • G to A, chromosome 10 at 13,507,430 bp
  • A to G, chromosome 10 at 28,863,376 bp
  • T to A, chromosome 10 at 42,011,898 bp
  • A to G, chromosome 10 at 58,813,947 bp
  • T to A, chromosome 10 at 67,226,078 bp
  • C to A, chromosome 10 at 122,782,278 bp
  • T to C, chromosome 11 at 77,973,759 bp
  • C to A, chromosome 11 at 80,193,907 bp
  • C to T, chromosome 11 at 86,486,493 bp
  • A to G, chromosome 11 at 105,970,685 bp
  • A to G, chromosome 11 at 114,779,215 bp
  • C to T, chromosome 12 at 81,581,854 bp
  • G to A, chromosome 13 at 56,537,381 bp
  • T to C, chromosome 14 at 24,170,461 bp
  • C to A, chromosome 14 at 50,424,654 bp
  • C to T, chromosome 14 at 66,834,368 bp
  • A to G, chromosome 15 at 10,495,923 bp
  • G to A, chromosome 15 at 36,106,955 bp
  • T to C, chromosome 15 at 39,842,066 bp
  • G to T, chromosome 15 at 102,967,267 bp
  • T to G, chromosome 16 at 15,829,769 bp
  • G to T, chromosome 16 at 20,597,542 bp
  • C to T, chromosome 16 at 29,415,831 bp
  • A to G, chromosome 17 at 20,375,164 bp
  • C to T, chromosome 17 at 26,118,872 bp
  • C to T, chromosome 17 at 30,803,108 bp
  • C to A, chromosome 17 at 42,503,135 bp
  • T to C, chromosome 18 at 53,536,741 bp
  • A to G, chromosome 19 at 10,186,403 bp
  • T to C, chromosome 19 at 33,501,586 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5640 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043289-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.