Strain Name:
C57BL/6J-MtgxR5800Btlr
Stock Number:
043389-MU
Citation ID:
RRID:MMRRC_043389-MU
Other Names:
R5800 (G1)
Major Collection:

Gene Information

Abca12
Name: ATP-binding cassette, sub-family A (ABC1), member 12
Synonyms: 4832428G11Rik, 4833417A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74591
Homologene: 45441
Ephx2
Name: epoxide hydrolase 2, cytoplasmic
Synonyms: Eph2, sEP, sEH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13850
VEGA: 14
HGNC: HGNC:3402
Homologene: 37558
Kdm1a
Name: lysine (K)-specific demethylase 1A
Synonyms: 1810043O07Rik, LSD1, Aof2, Kdm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 99982
Homologene: 32240
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: E130319N12Rik, 2810017C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215351
Homologene: 9196
Drosha
Name: drosha, ribonuclease type III
Synonyms: 1110013A17Rik, Etohi2, Rnasen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14000
Homologene: 8293
Esyt2
Name: extended synaptotagmin-like protein 2
Synonyms: 2410017M09Rik, 4921504I16Rik, 2310058N22Rik, D12Ertd551e, Fam62b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 52635
VEGA: 12
Homologene: 32699
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: Tweek, FSA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229227
Homologene: 52105
Fip1l1
Name: FIP1 like 1 (S. cerevisiae)
Synonyms: Rje, 1300019H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66899
Homologene: 136254
Tmem234
Name: transmembrane protein 234
Synonyms: 1500002D11Rik, 4933407D05Rik, 2510006D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76799
Homologene: 41314
Zfyve27
Name: zinc finger, FYVE domain containing 27
Synonyms: 9530077C24Rik, 2210011N02Rik, protrudin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319740
Homologene: 16939
L1td1
Name: LINE-1 type transposase domain containing 1
Synonyms: ECAT11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381591
Homologene: 135709
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171395
Homologene: 51376
H2-T23
Name: histocompatibility 2, T region locus 23
Synonyms: H-2T23, T18c(37), T18c, 37c, 37b, T23d, T23b, Qed-1, Qa1, Qa-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15040
HGNC: HGNC:4962
Homologene: 134018
Efhc1
Name: EF-hand domain (C-terminal) containing 1
Synonyms: 1700029F22Rik, mRib72-1, myoclonin1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71877
Homologene: 10003
Pcdh7
Name: protocadherin 7
Synonyms: BH-protocadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54216
HGNC: HGNC:8659
Homologene: 36101
Prl8a6
Name: prolactin family 8, subfamily a, member 6
Synonyms: Prlpc, PLP-Ca, PLP-calpha, Prlpc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19112
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Ipcef1
Name: interaction protein for cytohesin exchange factors 1
Synonyms: A130090K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320495
Homologene: 32271
Tbc1d20
Name: TBC1 domain family, member 20
Synonyms: 1110028I04Rik, 2810442O16Rik, bs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67231
Homologene: 32574
Fyttd1
Name: forty-two-three domain containing 1
Synonyms: 4933423A17Rik, 2010005M05Rik, 3830411L18Rik, 3830421F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 69823
Homologene: 12334
Nynrin
Name: NYN domain and retroviral integrase containing
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 277154
VEGA: 14
Homologene: 19483
Scn5a
Name: sodium channel, voltage-gated, type V, alpha
Synonyms: Nav1.5c, Nav1.5, mH1, SkM2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20271
Homologene: 22738
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68553
Homologene: 130754
Slc19a1
Name: solute carrier family 19 (folate transporter), member 1
Synonyms: RFC1, RFC-1, reduced folate carrier
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20509
Homologene: 57139
Rap1gap
Name: Rap1 GTPase-activating protein
Synonyms: 2310004O14Rik, 1300019I11Rik, Rap1ga1, Gap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 110351
HGNC: HGNC:9858
Homologene: 2163
Vmn2r98
Name: vomeronasal 2, receptor 98
Synonyms: EG224552
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224552
Homologene: 115024
Mctp1
Name: multiple C2 domains, transmembrane 1
Synonyms: 2810465F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78771
Homologene: 75211
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
Olfr1474
Name: olfactory receptor 1474
Synonyms: GA_x6K02T2RE5P-3803583-3804527, MOR202-26P, MOR202-42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258123
Homologene: 79417
Cfap45
Name: cilia and flagella associated protein 45
Synonyms: 1700028D05Rik, Nesg1, Ccdc19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71870
Homologene: 71837
1520401A03Rik
Name: RIKEN cDNA 1520401A03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 320309
Lyg1
Name: lysozyme G-like 1
Synonyms: 2300002O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 69541
Homologene: 18376
Vmn1r237
Name: vomeronasal 1 receptor 237
Synonyms: V1rf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171234
Homologene: 64475
Sdc2
Name: syndecan 2
Synonyms: fibroglycan, Synd2, Hspg1, 4833414L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 15529
Homologene: 2253
Krt39
Name: keratin 39
Synonyms: 4732494G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237934
Homologene: 19078
Klk1b27
Name: kallikrein 1-related peptidase b27
Synonyms: mGK-27, Klk27, Klk21l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16619
HGNC: HGNC:6364
Homologene: 68141
Ero1b
Name: endoplasmic reticulum oxidoreductase 1 beta
Synonyms: 1700065B09Rik, 1300013B24Rik, Ero1lb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67475
VEGA: 13
Homologene: 8740
Gm7353
Name: predicted pseudogene 7353
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 664817
Adamts8
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
Synonyms: METH2, METH-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 30806
HGNC: HGNC:224
Homologene: 5108
Lrrc8b
Name: leucine rich repeat containing 8 family, member B
Synonyms: R75581, 2210408K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433926
Homologene: 9103
Gpr153
Name: G protein-coupled receptor 153
Synonyms: 1110065N12Rik, PGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100129
Homologene: 18662
Dnah7c
Name: dynein, axonemal, heavy chain 7C
Synonyms: Dnahc7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100101919
Homologene: 41287
Tmc7
Name: transmembrane channel-like gene family 7
Synonyms: C630024K23Rik, 1700030H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 209760
Homologene: 36424
Casp4
Name: caspase 4, apoptosis-related cysteine peptidase
Synonyms: ich-3, Caspase-11, Casp11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12363
HGNC: HGNC:1505
Homologene: 136493
Shisa5
Name: shisa family member 5
Synonyms: 2310008D10Rik, 6430628I05Rik, Scotin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66940
Homologene: 133951
Smim8
Name: small integral membrane protein 8
Synonyms: 2810406B13Rik, 1810030N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66291
Homologene: 10708
Gm12888
Name: predicted gene 12888
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 545677
Homologene: 111034
Ptcd1
Name: pentatricopeptide repeat domain 1
Synonyms: 1110069M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71799
Homologene: 33161
Gm34653
Name: predicted gene, 34653
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 102637973
Homologene: 131655
Ighv1-16
Name: immunoglobulin heavy variable 1-16
Synonyms: Gm7012
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 629866
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 20,978,781 bp
  • C to T, chromosome 1 at 37,946,953 bp
  • A to T, chromosome 1 at 46,647,015 bp
  • A to T, chromosome 1 at 71,321,432 bp
  • T to A, chromosome 1 at 172,538,600 bp
  • T to C, chromosome 2 at 34,838,642 bp
  • T to A, chromosome 2 at 152,308,325 bp
  • A to G, chromosome 3 at 37,052,443 bp
  • TTTAATGAAGAGCT to TT, chromosome 4 at 34,771,261 bp
  • T to C, chromosome 4 at 98,733,762 bp
  • T to A, chromosome 4 at 121,319,428 bp
  • T to C, chromosome 4 at 129,607,131 bp
  • T to A, chromosome 4 at 136,573,070 bp
  • C to A, chromosome 4 at 137,720,377 bp
  • C to T, chromosome 4 at 152,280,077 bp
  • T to A, chromosome 5 at 57,722,225 bp
  • T to A, chromosome 5 at 74,546,081 bp
  • C to T, chromosome 5 at 105,481,342 bp
  • T to A, chromosome 5 at 145,159,665 bp
  • A to T, chromosome 7 at 3,110,168 bp
  • A to T, chromosome 7 at 44,055,664 bp
  • A to G, chromosome 7 at 118,539,440 bp
  • T to C, chromosome 7 at 141,640,423 bp
  • G to A, chromosome 9 at 5,308,915 bp
  • A to T, chromosome 9 at 30,954,482 bp
  • A to T, chromosome 9 at 80,126,433 bp
  • A to G, chromosome 9 at 106,080,275 bp
  • G to A, chromosome 9 at 109,056,094 bp
  • A to G, chromosome 9 at 119,501,666 bp
  • T to A, chromosome 10 at 6,890,569 bp
  • A to G, chromosome 10 at 77,042,269 bp
  • T to A, chromosome 11 at 8,861,302 bp
  • A to T, chromosome 11 at 99,521,145 bp
  • T to A, chromosome 12 at 114,665,911 bp
  • A to T, chromosome 12 at 116,370,188 bp
  • T to A, chromosome 13 at 12,602,301 bp
  • G to T, chromosome 13 at 27,435,470 bp
  • A to G, chromosome 13 at 76,688,559 bp
  • T to C, chromosome 14 at 55,870,631 bp
  • T to C, chromosome 14 at 66,107,302 bp
  • C to T, chromosome 15 at 12,865,067 bp
  • C to A, chromosome 15 at 12,902,647 bp
  • A to T, chromosome 15 at 33,028,144 bp
  • C to T, chromosome 16 at 32,891,288 bp
  • A to T, chromosome 17 at 19,065,998 bp
  • C to G, chromosome 17 at 21,314,807 bp
  • G to A, chromosome 17 at 23,717,992 bp
  • G to T, chromosome 17 at 36,031,604 bp
  • T to C, chromosome 19 at 13,471,896 bp
  • T to C, chromosome 19 at 41,104,934 bp
  • T to C, chromosome 19 at 42,182,663 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5800 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043389-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.