Strain Name:
C57BL/6J-MtgxR5899Btlr
Stock Number:
044098-MU
Citation ID:
RRID:MMRRC_044098-MU
Other Names:
R5899 (G1)
Major Collection:

Gene Information

Grm1
Name: glutamate receptor, metabotropic 1
Synonyms: rcw, nmf373, mGluR1, Grm1, Gprc1a, 4930455H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14816
HGNC: HGNC:4593
Homologene: 649
Dst
Name: dystonin
Synonyms: A830042E19Rik, 2310001O04Rik, Macf2, bullous pemphigoid antigen 1, BPAG1-n, BPAG1, athetoid, Bpag, ah, bullous pemphigoid antigen 1, Bpag1, nmf339, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Rfx3
Name: regulatory factor X, 3 (influences HLA class II expression)
Synonyms: C230093O12Rik, MRFX3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 19726
HGNC: HGNC:9984
Homologene: 7917
Ddx50
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
Synonyms: 8430408E17Rik, 4933429B04Rik, GU2, RH-II/Gubeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 94213
VEGA: 10
Homologene: 56986
Clcn6
Name: chloride channel, voltage-sensitive 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 26372
HGNC: HGNC:2024
Homologene: 985
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: 2810017C20Rik, E130319N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 215351
Homologene: 9196
Fxr2
Name: fragile X mental retardation, autosomal homolog 2
Synonyms: Fxr2h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 23879
HGNC: HGNC:4024
Homologene: 21014
Racgap1
Name: Rac GTPase-activating protein 1
Synonyms: MgcRacGAP, gtl11, Band25, GTPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 26934
HGNC: HGNC:9804
Homologene: 8077
Cdk5rap2
Name: CDK5 regulatory subunit associated protein 2
Synonyms: 2900018K03Rik, an
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 214444
Homologene: 49533
Map3k11
Name: mitogen-activated protein kinase kinase kinase 11
Synonyms: Mlk3, 2610017K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 26403
VEGA: 19
HGNC: HGNC:6850
Homologene: 37618
Pdcd11
Name: programmed cell death 11
Synonyms: ALG-4, 1110021I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18572
VEGA: 19
Homologene: 74968
Ttc37
Name: tetratricopeptide repeat domain 37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218343
VEGA: 13
Homologene: 40966
Igf2bp3
Name: insulin-like growth factor 2 mRNA binding protein 3
Synonyms: Koc13, 2610101N11Rik, IMP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 140488
Homologene: 4773
Samd7
Name: sterile alpha motif domain containing 7
Synonyms: 4930597A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75953
Homologene: 18802
Ahi1
Name: Abelson helper integration site 1
Synonyms: 1700015F03Rik, Ahi-1, Jouberin, D10Bwg0629e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 52906
VEGA: 10
Homologene: 9762
Dock7
Name: dedicator of cytokinesis 7
Synonyms: m, 3110056M06Rik, LOC242555
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67299
Homologene: 23566
Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Synonyms: spastic paraplegia 11, 6030465E24Rik, C530005A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 214585
Homologene: 41614
Rplp0
Name: ribosomal protein, large, P0
Synonyms: Arbp, 36B4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11837
Homologene: 6517
Il2ra
Name: interleukin 2 receptor, alpha chain
Synonyms: CD25, IL-2R alpha chain, Il2r, Ly-43
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16184
HGNC: HGNC:6008
Homologene: 360
Strip2
Name: striatin interacting protein 2
Synonyms: D330017J20Rik, Fam40b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320609
Homologene: 66198
Hsd17b13
Name: hydroxysteroid (17-beta) dehydrogenase 13
Synonyms: Pan1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243168
Homologene: 71549
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4933421G18Rik, 4921518A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 71175
VEGA: 15
Homologene: 15850
Scpep1
Name: serine carboxypeptidase 1
Synonyms: 2410018F01Rik, Risc, 4833411K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74617
Homologene: 41443
Atp12a
Name: ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Synonyms: Atp1al1, cHKA, HKalpha2, ATPase H+K+-transporting, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 192113
VEGA: 14
Homologene: 68197
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 665700
Homologene: 90772
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1537Clo, b2b1565Clo, b2b3491Clo, b2b1154Clo, Mdnah5, Dnahc5, b2b1134Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Olfr395
Name: olfactory receptor 395
Synonyms: MOR135-10, GA_x6K02T2P1NL-4062605-4061667
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 259007
HGNC: null
Homologene: null
Bpifb2
Name: BPI fold containing family B, member 2
Synonyms: 2310034L21Rik, Bpil1, 2310069A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66557
Homologene: 11884
Vmn2r77
Name: vomeronasal 2, receptor 77
Synonyms: EG546983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 546983
HGNC: null
Homologene: 115466
Ptgfr
Name: prostaglandin F receptor
Synonyms: PGF, FP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 19220
HGNC: HGNC:9600
Homologene: 741
Morn3
Name: MORN repeat containing 3
Synonyms: 4930438O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74890
Homologene: 42069
Gm5155
Name: predicted gene 5155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381852
HGNC: null
Homologene: 115938
Gbp7
Name: guanylate binding protein 7
Synonyms: 9830147J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229900
Homologene: 138296
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Spire2
Name: spire type actin nucleation factor 2
Synonyms: Spir-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234857
Homologene: 72212
Cnga1
Name: cyclic nucleotide gated channel alpha 1
Synonyms: Cncg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12788
HGNC: HGNC:2148
Homologene: 55432
Wnt11
Name: wingless-type MMTV integration site family, member 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22411
Homologene: 20970
Fbxw15
Name: F-box and WD-40 domain protein 15
Synonyms: Fbxo12J
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382105
Homologene: 110776
Ano3
Name: anoctamin 3
Synonyms: Tmem16c, B230324K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228432
Homologene: 57147
Olfr168
Name: olfactory receptor 168
Synonyms: GA_x54KRFPKG5P-15979009-15978071, MOR271-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258354
Homologene: 128057
Klk15
Name: kallikrein related-peptidase 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 317652
Homologene: 77571
Anks1b
Name: ankyrin repeat and sterile alpha motif domain containing 1B
Synonyms: C030032C09Rik, Gm10937, LOC380650, AIDA-1b, E530015N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 77531
Homologene: 51570
Sesn1
Name: sestrin 1
Synonyms: SEST1, 1110002G11Rik, PA26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 140742
Homologene: 8697
Olfr825
Name: olfactory receptor 825
Synonyms: MOR210-1, GA_x6K02T2PULF-11834065-11833103
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258672
Homologene: 121503
Serpinb2
Name: serine (or cysteine) peptidase inhibitor, clade B, member 2
Synonyms: ovalbumin, PAI-2, Planh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18788
HGNC: HGNC:8584
Homologene: 20571
Cflar
Name: CASP8 and FADD-like apoptosis regulator
Synonyms: Casper, 2310024N18Rik, c-Flip, Cash, A430105C05Rik, Flip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12633
HGNC: HGNC:1876
Homologene: 7652
Zbp1
Name: Z-DNA binding protein 1
Synonyms: mZaDLM, Dai, 2010010H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 58203
Homologene: 10972
B230104I21Rik
Name: RIKEN cDNA B230104I21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
E130208F15Rik
Name: RIKEN cDNA E130208F15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 34,295,289 bp
  • A to G, chromosome 1 at 58,752,768 bp
  • G to T, chromosome 1 at 107,519,716 bp
  • A to G, chromosome 2 at 11,684,437 bp
  • A to T, chromosome 2 at 31,354,673 bp
  • G to A, chromosome 2 at 76,867,175 bp
  • T to G, chromosome 2 at 110,862,887 bp
  • T to C, chromosome 2 at 122,098,199 bp
  • A to G, chromosome 2 at 153,891,130 bp
  • T to A, chromosome 2 at 173,210,547 bp
  • T to G, chromosome 3 at 30,756,734 bp
  • A to G, chromosome 3 at 142,546,542 bp
  • C to T, chromosome 3 at 151,835,101 bp
  • T to C, chromosome 4 at 70,243,593 bp
  • A to T, chromosome 4 at 98,991,423 bp
  • A to G, chromosome 4 at 148,017,592 bp
  • G to T, chromosome 4 at 154,349,529 bp
  • C to T, chromosome 5 at 72,619,061 bp
  • T to A, chromosome 5 at 103,965,864 bp
  • T to A, chromosome 5 at 115,561,430 bp
  • A to G, chromosome 5 at 123,041,103 bp
  • T to A, chromosome 6 at 29,956,958 bp
  • A to G, chromosome 6 at 49,117,150 bp
  • A to G, chromosome 7 at 17,917,444 bp
  • T to C, chromosome 7 at 30,322,301 bp
  • G to T, chromosome 7 at 43,938,823 bp
  • A to G, chromosome 7 at 86,811,716 bp
  • T to A, chromosome 7 at 98,839,176 bp
  • A to C, chromosome 8 at 123,354,094 bp
  • T to C, chromosome 9 at 80,142,070 bp
  • T to C, chromosome 9 at 109,555,673 bp
  • T to C, chromosome 10 at 10,689,348 bp
  • T to C, chromosome 10 at 21,000,566 bp
  • T to C, chromosome 10 at 41,811,193 bp
  • T to A, chromosome 10 at 62,640,817 bp
  • T to A, chromosome 10 at 90,923,517 bp
  • T to A, chromosome 10 at 130,162,673 bp
  • A to G, chromosome 11 at 69,652,685 bp
  • A to G, chromosome 11 at 73,906,929 bp
  • A to G, chromosome 11 at 88,934,576 bp
  • A to G, chromosome 13 at 76,111,819 bp
  • T to C, chromosome 14 at 56,373,344 bp
  • A to G, chromosome 15 at 8,334,844 bp
  • T to C, chromosome 15 at 28,448,367 bp
  • T to C, chromosome 15 at 99,623,628 bp
  • C to T, chromosome 16 at 19,530,801 bp
  • G to A, chromosome 17 at 30,656,685 bp
  • T to G, chromosome 19 at 5,695,909 bp
  • T to C, chromosome 19 at 27,830,765 bp
  • A to G, chromosome 19 at 47,104,759 bp
  • A to T, chromosome 19 at 56,340,574 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5899 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044098-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.