Strain Name:
C57BL/6J-MtgxR5903Btlr
Stock Number:
044101-MU
Citation ID:
RRID:MMRRC_044101-MU
Other Names:
R5903 (G1)
Major Collection:

Gene Information

Kif5a
Name: kinesin family member 5A
Synonyms: D10Bwg0738e, Kns, Khc, Kif5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16572
VEGA: 10
HGNC: HGNC:6323
Homologene: 55861
Atg7
Name: autophagy related 7
Synonyms: 1810013K23Rik, Apg7l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74244
Homologene: 4662
Ccdc88c
Name: coiled-coil domain containing 88C
Synonyms: Daple, 0610010D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68339
VEGA: 12
Homologene: 18903
Mta1
Name: metastasis associated 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 116870
HGNC: HGNC:7410
Homologene: 3442
Lrig3
Name: leucine-rich repeats and immunoglobulin-like domains 3
Synonyms: 9430095K15Rik, 9030421L11Rik, 9130004I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 320398
VEGA: 10
Homologene: 62452
B4galt1
Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Synonyms: B-1,4-GalT1, b1,4-Galactosyltransferase I, beta 1,4-Galactosyltransferase I, Ggtb2, Ggtb, beta-1,4-GalT1, GalT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14595
HGNC: HGNC:924
Homologene: 20378
Kdm3a
Name: lysine (K)-specific demethylase 3A
Synonyms: Jmjd1a, Tsga, 1700105C21Rik, C230043E16Rik, Jmjd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 104263
Homologene: 10196
Fzd6
Name: frizzled class receptor 6
Synonyms: Fz6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14368
VEGA: 15
HGNC: HGNC:4044
Homologene: 2617
Cep97
Name: centrosomal protein 97
Synonyms: 4932439K18Rik, 2810403B08Rik, E130116N02Rik, Lrriq2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74201
Homologene: 11579
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103554
Homologene: 113742
Hsf2
Name: heat shock factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15500
VEGA: 10
HGNC: HGNC:5225
Homologene: 37931
Sart3
Name: squamous cell carcinoma antigen recognized by T cells 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53890
Homologene: 40977
Ipo7
Name: importin 7
Synonyms: RanBP7, Imp7, A330055O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233726
HGNC: HGNC:9852
Homologene: 4659
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: IP3R1, opt, Pcp1, wblo, Pcp-1, Ip3r, P400, InsP3R type I, Itpr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Atg2b
Name: autophagy related 2B
Synonyms: C030004M05Rik, 2410024A21Rik, C630028L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 76559
VEGA: 12
Homologene: 9974
Cntrob
Name: centrobin, centrosomal BRCA2 interacting protein
Synonyms: 9830165K03Rik, Nip2, Lip8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216846
Homologene: 14205
Klf12
Name: Kruppel-like factor 12
Synonyms: D530033K05Rik, AP-2rep, 2700063E05Rik, B130052C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16597
VEGA: 14
HGNC: HGNC:6346
Homologene: 21417
Sez6l2
Name: seizure related 6 homolog like 2
Synonyms: Psk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233878
Homologene: 8237
Unc5a
Name: unc-5 netrin receptor A
Synonyms: Unc5h1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 107448
Homologene: 41474
Tubb4b
Name: tubulin, beta 4B class IVB
Synonyms: 4930542G03Rik, Tubb2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227613
Homologene: 68504
Cdcp1
Name: CUB domain containing protein 1
Synonyms: E030027H19Rik, 9030022E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 109332
Homologene: 11276
Hsd17b14
Name: hydroxysteroid (17-beta) dehydrogenase 14
Synonyms: Dhrs10, retSDR3, 0610039E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66065
Homologene: 133800
Gle1
Name: GLE1 RNA export mediator (yeast)
Synonyms: 4933405K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74412
HGNC: HGNC:4315
Homologene: 20379
Kctd10
Name: potassium channel tetramerisation domain containing 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330171
Homologene: 32652
Baz2b
Name: bromodomain adjacent to zinc finger domain, 2B
Synonyms: 5830435C13Rik, D2Ertd794e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 407823
HGNC: HGNC:963
Homologene: 8394
Edc4
Name: enhancer of mRNA decapping 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234699
Homologene: 40937
Clec4d
Name: C-type lectin domain family 4, member d
Synonyms: mcl, Mpcl, Clecsf8, mMCL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17474
Homologene: 7844
Itpkb
Name: inositol 1,4,5-trisphosphate 3-kinase B
Synonyms: 1110033J02Rik, E130307H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 320404
HGNC: HGNC:6179
Homologene: 1672
Cntn3
Name: contactin 3
Synonyms: Pang
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18488
HGNC: HGNC:2173
Homologene: 7461
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 672511
Homologene: 45439
Pdzd8
Name: PDZ domain containing 8
Synonyms: Pdzk8, A630041P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107368
VEGA: 19
Homologene: 14879
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22635
Homologene: 124417
Fam160b2
Name: family with sequence similarity 160, member B2
Synonyms: Rai16, G430067P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239170
VEGA: 14
Homologene: 23379
Actl7a
Name: actin-like 7a
Synonyms: t-actin 2, Tact2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11470
HGNC: HGNC:161
Homologene: 7613
Fmnl1
Name: formin-like 1
Synonyms: formin-related gene in leukocytes, 8030453N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 57778
HGNC: HGNC:1212
Homologene: 135620
Krt81
Name: keratin 81
Synonyms: Krt2-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 64818
VEGA: 15
HGNC: HGNC:6458
Homologene: 55645
Olfr618
Name: olfactory receptor 618
Synonyms: GA_x6K02T2PBJ9-6320148-6321104, MOR31-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259049
Homologene: 72966
Oas1h
Name: 2'-5' oligoadenylate synthetase 1H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 246729
HGNC: HGNC:8086
Homologene: 77345
Atp6v0a2
Name: ATPase, H+ transporting, lysosomal V0 subunit A2
Synonyms: TJ6s, ATP6a2, Atp6n2, 8430408C20Rik, Tj6, V-ATPase a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 21871
Homologene: 56523
Ugt1a6a
Name: UDP glucuronosyltransferase 1 family, polypeptide A6A
Synonyms: UGT1.6, Ugt1a6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 94284
Homologene: 85959
Slc9b1
Name: solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
Synonyms: 4933425K02Rik, 1700094G20Rik, Nhedc1, 4933424B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74446
Homologene: 49914
Thsd4
Name: thrombospondin, type I, domain containing 4
Synonyms: ADAMTSL6, B230114P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 207596
Homologene: 49796
Kcnh8
Name: potassium voltage-gated channel, subfamily H (eag-related), member 8
Synonyms: C130090D05Rik, Kv12.1, ELK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 211468
Homologene: 14332
9130230L23Rik
Name: RIKEN cDNA 9130230L23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231253
Ms4a1
Name: membrane-spanning 4-domains, subfamily A, member 1
Synonyms: Ly-44, Cd20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12482
HGNC: HGNC:7315
Homologene: 7259
Cyp2j8
Name: cytochrome P450, family 2, subfamily j, polypeptide 8
Synonyms: Cyp2j8-ps, OTTMUSG00000007938
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 665095
Homologene: 133819
Abraxas1
Name: BRCA1 A complex subunit
Synonyms: Fam175a, Ccdc98, 3830405G04Rik, 5630400M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70681
Homologene: 16376
Olfr95
Name: olfactory receptor 95
Synonyms: MOR263-6, GA_x6K02T2PSCP-1651760-1650822
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258506
HGNC: HGNC:8165
Homologene: 71990
P2rx3
Name: purinergic receptor P2X, ligand-gated ion channel, 3
Synonyms: P2X3, 4930513E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228139
HGNC: HGNC:8534
Homologene: 1922
Stmn3
Name: stathmin-like 3
Synonyms: Sclip, 9330161A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20262
Homologene: 7528
Trdv5
Name: T cell receptor delta variable 5
Synonyms: Gm6683
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 626545
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 88,215,123 bp
  • G to T, chromosome 1 at 180,413,975 bp
  • C to T, chromosome 2 at 25,223,981 bp
  • C to A, chromosome 2 at 29,940,281 bp
  • C to T, chromosome 2 at 59,959,889 bp
  • T to C, chromosome 2 at 85,000,727 bp
  • T to C, chromosome 2 at 181,308,780 bp
  • C to T, chromosome 3 at 135,392,894 bp
  • T to C, chromosome 4 at 40,807,760 bp
  • G to T, chromosome 4 at 56,743,827 bp
  • T to A, chromosome 4 at 96,507,277 bp
  • A to G, chromosome 5 at 65,988,318 bp
  • T to C, chromosome 5 at 100,817,958 bp
  • T to C, chromosome 5 at 113,751,239 bp
  • G to A, chromosome 5 at 114,380,462 bp
  • T to C, chromosome 5 at 120,870,977 bp
  • T to A, chromosome 5 at 124,712,279 bp
  • C to A, chromosome 5 at 137,442,134 bp
  • C to A, chromosome 6 at 71,632,250 bp
  • T to A, chromosome 6 at 102,242,133 bp
  • T to C, chromosome 6 at 108,489,797 bp
  • G to A, chromosome 6 at 114,706,293 bp
  • A to G, chromosome 6 at 123,267,061 bp
  • T to C, chromosome 7 at 45,565,962 bp
  • G to T, chromosome 7 at 103,597,921 bp
  • T to A, chromosome 7 at 110,050,813 bp
  • T to C, chromosome 7 at 126,970,133 bp
  • A to G, chromosome 8 at 105,890,587 bp
  • T to A, chromosome 9 at 60,394,106 bp
  • G to A, chromosome 9 at 123,173,772 bp
  • T to C, chromosome 10 at 57,504,723 bp
  • T to C, chromosome 10 at 126,008,478 bp
  • T to A, chromosome 10 at 127,230,578 bp
  • A to T, chromosome 11 at 30,841,589 bp
  • A to C, chromosome 11 at 69,309,375 bp
  • G to T, chromosome 11 at 103,171,444 bp
  • T to C, chromosome 11 at 119,421,369 bp
  • T to C, chromosome 12 at 100,930,542 bp
  • T to C, chromosome 12 at 105,639,359 bp
  • C to T, chromosome 12 at 113,136,619 bp
  • T to A, chromosome 13 at 54,999,690 bp
  • A to T, chromosome 14 at 54,148,785 bp
  • A to T, chromosome 14 at 70,591,681 bp
  • A to G, chromosome 14 at 100,022,688 bp
  • T to A, chromosome 15 at 39,007,388 bp
  • T to G, chromosome 15 at 101,460,202 bp
  • G to A, chromosome 16 at 55,919,526 bp
  • A to T, chromosome 17 at 37,211,021 bp
  • G to T, chromosome 17 at 52,803,336 bp
  • A to T, chromosome 19 at 11,258,248 bp
  • A to G, chromosome 19 at 59,345,286 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5903 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044101-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.